Vet Immunol Immunopathol 2013 Jul 6;154(1-2):8-16. Epub 2013 May 6.
Universidad Autónoma de Nuevo León, Departamento de Microbiología e Inmunología, Laboratorio de Inmunología y Virología, Facultad de Ciencias Biológicas, Av. Pedro de Alba S/N, Cd. Universitaria, C.P. 66451 San Nicolás de los Garza, Nuevo León, Mexico.
It is known that macrophages from naturally resistant animals possess a strong immune response against bovine tuberculosis to control mycobacterial infections. In the present study, the macrophage phagocytic activity, intracellular bacterial survival, and cytokine gene expression induced by classical and alternative activators against Mycobacterium bovis in naturally resistant or susceptible bovines, were evaluated. Animals were classified as naturally resistant or susceptible based on the capacity of their macrophages to allow M. Read More