23,933 results match your criteria areas investigation


A numerical study of arsenic contamination at the Bagnoli bay seabed by a semi-anthropogenic source. Analysis of current regime.

Sci Total Environ 2021 Apr 5;782:146811. Epub 2021 Apr 5.

Italian Institute of Geophysics and Vulcanology (INGV), Italy; CNR-IRISS, Naples, Italy. Electronic address:

Bagnoli Coroglio is an urban district of the City of Naples (South Italy), which fronts the Tyrrhenian Sea for nearly 3 km. It is part of the Campi Flegrei caldera, one of the most explosive volcanic areas in Europe. The need for redeveloping the site after the intense industrial activities of the twentieth century has prompted a remarkable research effort to investigate the pollution's degree, nature, and extent at both the land and seafloor. Read More

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Chemical fingerprinting strategies based on comprehensive two-dimensional gas chromatography combined with gas chromatography-olfactometry to capture the unique signature of Piemonte peppermint essential oil (Mentha x piperita var Italo-Mitcham).

J Chromatogr A 2021 Mar 26;1645:462101. Epub 2021 Mar 26.

Soremartec Italia srl, Alba, Cuneo Italy.

Accurate, reliable, and informative mapping of untargeted and targeted components across many samples is here performed by combining off-line GC-Olfactometry (GC-O) and comprehensive two-dimensional gas chromatography (GC×GC) coupled to time-of-flight mass spectrometry with variable ionization energy (TOF MS featuring Tandem Ionization™). In particular, untargeted and targeted (UT) features patterns are processed by chromatographic fingerprinting, giving differential priority to potent odorants' retention-times regions. Distinguishing peppermint essential oil (EO) from Piedmont (Italy - Mentha × piperita L. Read More

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Ileal Crohn's Disease Exhibits Similar Transmural Fibrosis Irrespective of Phenotype.

Clin Transl Gastroenterol 2021 Apr 13;12(4):e00330. Epub 2021 Apr 13.

Unit of Pharmacology and Therapeutics, Department of Biomedicine, Faculty of Medicine, University of Porto, Portugal.

Introduction: In Crohn's disease (CD), the assessment of transmural inflammation and fibrosis is of utmost importance. This study aimed to quantify these parameters in CD ileal specimens and correlate them with disease progression.

Methods: This is a retrospective unicentric study based on the analysis of archived specimens (n = 103) of primary ileal resection. Read More

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Use of alternative care sites during the COVID-19 pandemic in the city of Buenos Aires, Argentina.

Public Health 2021 Mar 5;194:14-16. Epub 2021 Mar 5.

Ministry of Health, Ciudad Autónoma de Buenos Aires, Argentina.

Objectives: In large cities, where a large proportion of the population live in poverty and overcrowding, orders to stay home to comply with isolation requirements are difficult to fulfil. In this article, the use of alternative care sites (ACSs) for the isolation of patients with confirmed COVID-19 or persons under investigation (PUI) in the City of Buenos Aires during the first wave of COVID-19 are described.

Study Design: This is a cross-sectional study. Read More

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Anomaly detection for the individual analysis of brain PET images.

J Med Imaging (Bellingham) 2021 Mar 5;8(2):024003. Epub 2021 Apr 5.

Paris Brain Institute, Hôpital Pitié-Salpêtrière, Paris, France.

In clinical practice, positron emission tomography (PET) images are mostly analyzed visually, but the sensitivity and specificity of this approach greatly depend on the observer's experience. Quantitative analysis of PET images would alleviate this problem by helping define an objective limit between normal and pathological findings. We present an anomaly detection framework for the individual analysis of PET images. Read More

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Human cutaneous B cells: what do we really know?

Ann Transl Med 2021 Mar;9(5):440

Department of Dermatology, University of Rochester Medical Center, Rochester, NY, USA.

B cells play many critical roles in the systemic immune response, including antibody secretion, antigen presentation, T cell co-stimulation, and pro- and anti-inflammatory cytokine production. However, the contribution of B cells to the local immune response in many non-lymphoid tissues, such as the skin, is incompletely understood. Cutaneous B cells are scarce except in certain malignant and inflammatory conditions, and as such, have been poorly characterized until recently. Read More

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Climate and habitat configuration limit range expansion and patterns of dispersal in a non-native lizard.

Ecol Evol 2021 Apr 22;11(7):3332-3346. Epub 2021 Feb 22.

Faculty of Biological Sciences School of Biology University of Leeds Leeds LS2 9JT UK.

Invasive species are one of the main causes of biodiversity loss worldwide. As introduced, populations increase in abundance and geographical range, so does the potential for negative impacts on native communities. As such, there is a need to better understand the processes driving range expansion as species become established in recipient landscapes. Read More

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The Role of Parvalbumin Interneuron GIRK Signaling in the Regulation of Affect and Cognition in Male and Female Mice.

Front Behav Neurosci 2021 26;15:621751. Epub 2021 Mar 26.

Department of Biomedical Sciences, Marquette University, Milwaukee, WI, United States.

Pathological impairments in the regulation of affect (i.e., emotion) and flexible decision-making are commonly observed across numerous neuropsychiatric disorders and are thought to reflect dysfunction of cortical and subcortical circuits that arise in part from imbalances in excitation and inhibition within these structures. Read More

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