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Rural electrification using renewable energy resources and its environmental impact assessment.

Environ Sci Pollut Res Int 2022 Aug 17. Epub 2022 Aug 17.

Department of Electrical Engineering, Indian Institute of Technology, Roorkee, 247667, Uttarakhand, India.

Integrating a group of generation units and loads into a microgrid improves power supply sustainability, decreases greenhouse gas emissions, and lowers generating costs. However, this integration necessitates the development of an improved energy management system. The microgrid distributes electricity among energy resources to optimize either the generating cost or the quantity of greenhouse gas emissions, or both at the same time. Read More

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Development and psychometric testing of burn inpatient nursing dependency assessment scale.

J Adv Nurs 2022 Aug 16. Epub 2022 Aug 16.

Department of Nursing Administration, The First Affiliated Hospital of Naval Medical University (Changhai Hospital), Shanghai, China.

Aims: The aim was to develop and psychometrically test the burn inpatient nursing dependency assessment scale (BINDAS).

Design: This was a scale development study.

Methods: This study was conducted in four phases from November 2019 to November 2021. Read More

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Regulated synthesis of Zr-metal-organic frameworks with variable hole size and its influence on the performance of novel MOF-based heterogeneous amino acid-thiourea catalysts.

RSC Adv 2022 Jul 3;12(33):21574-21581. Epub 2022 Aug 3.

Research Institute of Membrane Separation Technology of Shaanxi Province Co., Ltd Xi'an 710055 China.

We present an efficient and easy synthesis method for incorporating organocatalytic moieties into Zr-metal organic frameworks (Zr-MOFs). The catalytic activity and selectivity of the new chiral catalysts were improved by adjusting the aperture of the MOF cavities. The hole size of the Zr-MOF was modulated by adding acid and replacing bridge ligands during synthesis. Read More

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Prevention of muscle atrophy in ICU patients without nerve injury by neuromuscular electrical stimulation: a randomized controlled study.

BMC Musculoskelet Disord 2022 Aug 16;23(1):780. Epub 2022 Aug 16.

Department of Rehabilitation Medicine, Shanghai Jiao Tong University affiliated Sixth People's Hospital, Shanghai, China.

Background: Extensive muscle atrophy is a common occurrence in orthopaedics patients who are bedridden or immobilized. The incidence is higher in intensive care unit (ICU) inpatients. There is still controversy about how to use neuromuscular electrical stimulation (NMES) in ICU patients. Read More

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Incidence, early case fatality and determinants of stroke in Iran: Golestan Cohort Study.

J Stroke Cerebrovasc Dis 2022 Aug 13;31(10):106658. Epub 2022 Aug 13.

Digestive Disease Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Objectives: While few studies investigated the incidence of stroke in Iran, no Iranian cohort has estimated the standardized-incidence rate and early fatality of first-ever-stroke subtypes along with associated factors.

Methods: Golestan Cohort Study is a prospective study launched in northeastern Iran in 2004, including 50,045 individuals aged 40-75 at baseline. Age-standardized incidence rate of first-ever-stroke was calculated per 100,000 person-years, according to World Standard Population. Read More

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Factors associated with the progression of myosteatosis in patients with cirrhosis.

Nutrition 2022 Jun 17;103-104:111777. Epub 2022 Jun 17.

Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Nagoya, Japan.

Objectives: The presence of myosteatosis is one factor associated with poor prognosis for patients with cirrhosis; however, the factors contributing to worsening myosteatosis are, to our knowledge, unknown. The aim of this study was to clarify the changes in myosteatosis, and the factors involved in these changes.

Methods: The present study enrolled 178 patients with cirrhosis who underwent computed tomography twice to measure changes in skeletal muscle attenuation (SMA) at the L3 level. Read More

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Role of Transfusion Volume and Transfusion Rate as Markers of Futility During Ultramassive Blood Transfusion in Trauma.

J Am Coll Surg 2022 Sep 10;235(3):468-480. Epub 2022 Aug 10.

From the Division of Trauma, Emergency Surgery, and Surgical Critical Care (Dorken Gallastegi, Saillant, Hwabejire, Fawley, Parks, Kaafarani, Velmahos).

Background: Using a large national database, we evaluated the relationship between RBC transfusion volume, RBC transfusion rate, and in-hospital mortality to explore the presence of a futility threshold in trauma patients receiving ultramassive blood transfusion.

Study Design: The ACS-TQIP 2013 to 2018 database was analyzed. Adult patients who received ultramassive blood transfusion (≥20 units of RBC/24 hours) were included. Read More

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September 2022

Depth control in Follicular Unit Excision: a new classification from a detailed analysis of 30 patients undergoing FUE technique for hair restoration.

J Cosmet Dermatol 2022 Aug 16. Epub 2022 Aug 16.

Centro Goiano Transplante Capilar - CGTC.

Background: In Follicular Unit Excision (FUE), the concept of Depth Control (DC) has been created to minimize the risk of hair follicle damage.

Aim: To analyze DC variation in different parts of the safe donor area of scalp; to propose Boaventura's new DC classification for hair restoration surgery using the FUE technique.

Patients/methods: Thirty male patients underwent hair restoration surgery. Read More

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[Estimation of Agricultural Non-point Source TN and TP Export Coefficients Based on Soil Loss].

Huan Jing Ke Xue 2022 Aug;43(8):4032-4041

State Key Laboratory of Resources and Environmental Information System, Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences, Beijing 100101, China.

Taking the Yellow River Delta as a typical research area, we constructed a coastal agricultural TN and TP non-point source pollution estimating model by analyzing the relationship between the surface soil pollutant loss risks and the monitored pollutant flux into the sea. On this basis, TN and TP non-point source export coefficients of paddy fields, irrigated land, and dry land were calculated, and the verification showed that the estimated export coefficients were acceptable. In the study area, the TN and TP export coefficients into the sea of arable land were 18. Read More

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[Evaluation and Source Analysis of Heavy Metal Pollution in Sediments of the Yellow River Basin Based on Monte Carlo Simulation and PMF Model].

Huan Jing Ke Xue 2022 Aug;43(8):4008-4017

College of Environmental Science and Engineering, Beijing Forestry University, Beijing 100083, China.

As sediment is an essential component of rivers, the enrichment of heavy metals in sediment presents a serious threat to the aquatic environment. Many industrial cities are located along the Yellow River, and heavy metal pollution is a prominent problem in these areas. Thus, the study of heavy metal pollution in sediments of the Yellow River basin is of vital significance to the safety of the Yellow River basin ecosystem. Read More

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Towards a validated definition of the clinical transition to secondary progressive multiple sclerosis: A study from the Italian MS Register.

Mult Scler 2022 Aug 15:13524585221114007. Epub 2022 Aug 15.

Novartis Italia, Origgio, Lombardia, Italy.

Background: Definitions for reliable identification of transition from relapsing-remitting multiple sclerosis (MS) to secondary progressive (SP)MS in clinical cohorts are not available.

Objectives: To compare diagnostic performances of two different data-driven SPMS definitions.

Methods: Data-driven SPMS definitions based on a version of Lorscheider's algorithm (DDA) and on the EXPAND trial inclusion criteria were compared, using the neurologist's definition (ND) as gold standard, in terms of sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), Akaike information criterion (AIC) and area under the curve (AUC). Read More

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Infectious disease specialists and teamwork strategies worldwide: the World Association against Infection in Orthopedics and Trauma (WAIOT) and SICOT continue to cooperate in fighting musculoskeletal infections.

SICOT J 2022 15;8:E1. Epub 2022 Aug 15.

First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, 11527 Athens, Greece.

Bone and joint infections are associated with a devastating global burden. The successful treatment of these infections requires a multidisciplinary approach between orthopedic surgeons and experts of different disciplines. This multidisciplinary approach has gained ground over the past decades in modern infection units as a more effective treatment strategy, yielding better outcomes regarding infection eradication rates, length of hospital stay, and overall cost of treatments. Read More

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Contribution of Two-Dose Vaccination Toward the Reduction of COVID-19 Cases, ICU Hospitalizations and Deaths in Chile Assessed Through Explanatory Generalized Additive Models for Location, Scale, and Shape.

Front Public Health 2022 27;10:815036. Epub 2022 Jul 27.

Millennium Institute on Immunology and Immunotherapy, Departamento de Genética Molecular y Microbiología, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago, Chile.

Objectives: To assess the impact of the initial two-dose-schedule mass vaccination campaign in Chile toward reducing adverse epidemiological outcomes due to SARS-CoV-2 infection.

Methods: Publicly available epidemiological data ranging from 3 February 2021 to 30 September 2021 were used to construct GAMLSS models that explain the beneficial effect of up to two doses of vaccination on the following COVID-19-related outcomes: new cases per day, daily active cases, daily occupied ICU beds and daily deaths.

Results: Administered first and second vaccine doses, and the statistical interaction between the two, are strong, statistically significant predictors for COVID-19-related new cases per day (R = 0. Read More

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The optimal oral body temperature cutoff and other factors predictive of sepsis diagnosis in elderly patients.

Ann Thorac Med 2022 Jul-Sep;17(3):159-165. Epub 2022 Jul 9.

King Abdullah International Medical Research Center, Riyadh, Kingdom of Saudi Arabia.

Introduction: The aim of this study was to identify the optimal oral temperature cut-off value and other factors predictive of sepsis in elderly patients presenting to emergency department.

Methods: A hospital-based retrospective study was performed on all elderly patients who presented to the Adult Emergency Department at King Abdulaziz Medical City in Riyadh (January to December 31, 2018).

Results: Of total of 13,856 patients, 2170 (15. Read More

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Coupling analysis of population aging and economic growth with spatial-temporal variation: a case study in China.

Int J Equity Health 2022 Aug 13;21(1):107. Epub 2022 Aug 13.

Population Development and Policy Research Center, Chongqing Technology and Business University, Chongqing, China.

Background: China now faces an increasingly aging society which may exert economic pressure in the long run. This study illustrates the spatial pattern and evolution of population aging and economic development in China. The coupling coordination degree of population aging and economic development at the national and provincial levels are calculated and demonstrated, and the spatial patterns and characteristics are investigated. Read More

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The effects of the covid-19 pandemic on puberty: a cross-sectional, multicenter study from Turkey.

Ital J Pediatr 2022 Aug 13;48(1):144. Epub 2022 Aug 13.

Department of Pediatric Endocrinology and Diabetes, Koç University School of Medicine, Koç Üniversitesi Hastanesi, Davutpaşa Cd. No:4, Topkapı, 34010, Turkey.

Backgrounds: During the Coronavirus-19 disease (Covid-19) pandemic it was observed that the number of girls presenting with early puberty had increased. The aim of this study was to carry out a retrospective evaluation of the characteristics of girls who had been referred for evaluation of precocious puberty in five different pediatric endocrinology units, before and during the pandemic.

Methods: The study participants comprised 359 girls who were assigned into 2 groups a pre-pandemic group (n:214) and a pandemic group (n:145). Read More

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Tracking of menstrual cycles and prediction of the fertile window via measurements of basal body temperature and heart rate as well as machine-learning algorithms.

Reprod Biol Endocrinol 2022 Aug 13;20(1):118. Epub 2022 Aug 13.

Obstetrics and Gynecology Hospital, Institute of Reproduction and Development, Fudan University, No. 419, Fangxie Rd, Shanghai, 200011, China.

Background: Fertility awareness and menses prediction are important for improving fecundability and health management. Previous studies have used physiological parameters, such as basal body temperature (BBT) and heart rate (HR), to predict the fertile window and menses. However, their accuracy is far from satisfactory. Read More

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Safety and efficacy of prophylactic levetiracetam for prevention of epileptic seizures in the acute phase of intracerebral haemorrhage (PEACH): a randomised, double-blind, placebo-controlled, phase 3 trial.

Lancet Neurol 2022 09;21(9):781-791

Stroke Centre, Lyon University Hospital, Lyon, France; University Claude Bernard Lyon 1, Research on Healthcare Performance (RESHAPE), INSERM U1290, Lyon, France.

Background: The incidence of early seizures (occurring within 7 days of stroke onset) after intracerebral haemorrhage reaches 30% when subclinical seizures are diagnosed by continuous EEG. Early seizures might be associated with haematoma expansion and worse neurological outcomes. Current guidelines do not recommend prophylactic antiseizure treatment in this setting. Read More

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September 2022

Women's experience and perspectives toward genital cosmetic surgery in Erbil city/Iraq: a qualitative study.

BMC Womens Health 2022 08 12;22(1):340. Epub 2022 Aug 12.

School of Nursing and Midwifery, Hawler Medical University, Arbīl, Iraq.

Background: Nowadays, Female Genital Cosmetic Surgery is quite prevalent, resulting in a wide range of medical and cultural implications. The majority of women who undergo this operation suffer from anxiety, depression, and other emotional symptoms. The present study was carried out in order to explore women's perspective on and experience of genital cosmetic surgery given their special context and cultural aspects. Read More

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Loci and motifs of the GalNAcα1 → 3/O related glycotopes in the mammalian glycoconjugates and their lectin recognition roles.

Albert M Wu

Glycoconj J 2022 Aug 13. Epub 2022 Aug 13.

Glycome Research Laboratory, Institute of Molecular and Cellular Biology, College of Medicine, Chang-Gung University, Tao-yuan, 33302, Taiwan.

Galα1 → and GalNAcα1 → are the two essential key sugars in human blood group AB active glycotopes, in which GalNAcα1 → related sequences are located at both sides of the nonreducing and the reducing ends of human blood group A active O-glycans. It is also found at the nonreducing ends of GlcNAc N-glycans and glycosphingolipid(GSL) of human blood group A active glycotopes (A) and Forssman antigen (F). When monosaccharides and their α, β anomers are involved in basic units to express the complex size of the combining sites of the GalNAcα1 → specific lectins, they can be divided into a cavity site to accommodate the GalNAcα → key sugar and a subsite with a wide and broad range of recognition area to adopt the rest part of sugar sequences or glycotopes. Read More

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Association between obesity and COVID-19 mortality and length of stay in intensive care unit patients in Brazil: a retrospective cohort study.

Sci Rep 2022 Aug 12;12(1):13737. Epub 2022 Aug 12.

Hospital Vitória e Samaritano Barra, Américas Serviços Médicos, UnitedHealth Group Brazil, Rio de Janeiro, RJ, Brazil.

The present study aimed to evaluate the association between obesity and COVID-19 mortality and length of stay in ICU patients, and how these associations were modified by age groups. We performed a retrospective multicenter cohort study with data obtained from a hospital-based registry. The sample consisted of 8183 ICU hospitalized patients who tested positive for SARS-CoV-2. Read More

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Towards a North Pacific long-term monitoring program for ocean plastic pollution: A systematic review and recommendations for shorelines.

Environ Pollut 2022 Aug 9:119862. Epub 2022 Aug 9.

Department of Commerce, National Oceanic and Atmospheric Administration, National Marine Fisheries Service, Southeast Fisheries Science Center, Fisheries Statistics Division, Miami, FL, 33149, USA.

Increased organized monitoring is key to improving our understanding of marine debris on shorelines. Shorelines are demonstrated sinks for marine debris but efforts to quantify debris often fail to capture and report core variables and survey design techniques necessary to ensure study repeatability, comparability and to provide meaningful results. Here, we systematically review the available literature regarding marine debris distribution and abundance on shorelines of countries bordering the North Pacific Ocean (NPO), which are demonstrated to have unusually high marine debris abundance and diversity both at the ocean surface and stranded on shorelines. Read More

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The CORCOBIA study: Cut-off points of Alzheimer's disease CSF biomarkers in a clinical cohort.

Neurologia (Engl Ed) 2022 Aug 9. Epub 2022 Aug 9.

Unitat de Deteriorament Cognitiu i Transtorns del Moviment, Servei de Neurologia, Hospital del Mar, Parc de Salut Mar, Barcelona, Spain; Farmacologia Integrada i Neurociència de Sistemes, Programa de Neurociències, Institut Hospital del Mar d'Investigacions Mèdiques (IMIM), Barcelona, Spain. Electronic address:

Introduction: The analysis of the core biomarkers of Alzheimer's Disease (AD) in the cerebrospinal fluid (CSF) is recommended in the clinical units where it is available. Because of the absence of universal validated values, the determination of specific cut-off points for each center and its population is recommended. The main objective of the CORCOBIA study was to determine the cut-off points of core AD CSF biomarkers for several centers (Parc de Salut Mar, Barcelona and Hospital General de Granollers), which work with the same reference laboratory (Laboratori de Referència de Catalunya). Read More

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Safety and immunogenicity of a typhoid conjugate vaccine among children aged 9 months to 12 years in Malawi: a nested substudy of a double-blind, randomised controlled trial.

Lancet Glob Health 2022 Sep;10(9):e1326-e1335

Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, MD, USA. Electronic address:

Background: Typhoid fever is a substantial public health problem in Africa, yet there are few clinical trials of typhoid conjugate vaccine (TCV). We assessed immunogenicity and safety of Typbar TCV in Malawi.

Methods: This substudy was nested within a phase 3, double-blind, parallel design, randomised controlled trial of TCV in children from Ndirande Health Centre in Ndirande township, Blantyre, Malawi. Read More

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September 2022

Enhanced bedside mortality prediction combining point-of-care lactate and the quick Sequential Organ Failure Assessment (qSOFA) score in patients hospitalised with suspected infection in southeast Asia: a cohort study.

Lancet Glob Health 2022 Sep;10(9):e1281-e1288

Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Department of Tropical Hygiene, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

Background: Simple, bedside prediction of infection-related mortality in low-resource settings is crucial for triage and resource-utilisation decisions. We aimed to evaluate mortality prediction by combining point-of-care venous lactate with the quick Sequential Organ Failure Assessment (qSOFA) score in adult patients admitted to hospital with suspected infection in southeast Asia.

Methods: We performed a cohort study by prospectively enrolling patients aged 18 years or older who had been admitted to hospital within the previous 24 h for suspected infection (with at least three documented systemic manifestations of infection according to the 2012 Surviving Sepsis Campaign) at Sunpasitthiprasong Hospital in Ubon Ratchathani, Thailand (derivation cohort). Read More

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September 2022

Distributed wastewater treatment offers an environmentally preferable alternative to conventional septic systems in Central Florida.

Water Sci Technol 2022 Aug;86(3):432-444

OnSyte Performance, LLC., 2282 Killearn Center Blvd., Tallahassee, Florida 32309, USA.

Wastewater management is a critical issue globally. In Florida, the importance of this issue is heightened by the proximity to sensitive ecosystems. Distributed wastewater treatment units (DWTU) are a recent, state-approved alternative to septic system conversions to centralized sewer infrastructure. Read More

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The health-preserving culture of family of Russian serviceman.

Probl Sotsialnoi Gig Zdravookhranenniiai Istor Med 2022 Jul;30(4):616-620

The Federal State Public Military Educational Institution of Higher Education "The Jhukov Order Saratov Red Banner Institute of National Guard Forces of The Russian Federation", 410023, Saratov, Russia.

The article considers specifics of health-preserving culture of family members of serviceman and parameters of its sociological assessment. It is proved that military personnel consider family as social element of military collective and at the same time as sociocultural subsystem of military unit. The latter determines subordination of sociocultural interests of serviceman family to interests of development of military organization, which manifests itself as a factor complicating development, strengthening contradictions in system of health-preserving culture of this family. Read More

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Georgian Med News 2022 Jun(327):7-12

National Pirogov memorial medical university, Vinnytsya, Ukraine.

Objective was to to analyze the protein components of extracts of diagnostic allergens made in Ukraine in order to determine the next steps for their standardization. Electrophoresis in polyacrylamide gel was used to obtain electrophoregrams of Acarus siro, Dermatophagoides farinae, Dermatophagoides pteronyssinus, Alnus glutinosa, Betula pendula, Carpinus betulus, Ambrosia artemisiifolia, Artemisia absinthium, Dactylis glomerata, Festuca pratensis, Helianthus annuus, Lolium perenle, Poa pratensis, Secale cereale, Zea mays, cat hair, dog hair, sheep allergens, and allergen of feather pillows. The official site for the systematic nomenclature of allergens approved by the World Health Organization and the International Union of Immunological Societies was used to identify allergenic components. Read More

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Combined effects of calcium-alginate coating and essential oil on chicken breast meat quality.

Food Sci Nutr 2022 Aug 7;10(8):2505-2515. Epub 2022 Apr 7.

Centro Tecnológico de la Carne de Galicia Parque Tecnológico de Galicia Ourense Spain.

The objective of the present study was to evaluate the effects of calcium-alginate (CA) containing essential oils (AFEOs) as a potential antioxidant and antimicrobial coating on quality attributes and shelf life of chicken meat throughout keeping period (4°C). Five treatments were produced as follows: T1 (distilled water as control), T2 (2% CA), T3 (2% CA +500 ppm AFEOs), T4 (2% CA +1000 ppm AFEOs), and T5 (2% CA +1500 ppm AFEOs). The chicken meats packaged in polyethylene bags at atmospheric condition and physicochemical, microbiological, and organoleptic properties were assessed at days 1, 4, 8, and 12. Read More

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Dynamic prediction of mortality in COVID-19 patients in the intensive care unit: A retrospective multi-center cohort study.

Intell Based Med 2022 Aug 6:100071. Epub 2022 Aug 6.

Dept. of Intensive Care, Ziekenhuisgroep Twente, Almelo, the Netherlands.

Background: The COVID-19 pandemic continues to overwhelm intensive care units (ICUs) worldwide, and improved prediction of mortality among COVID-19 patients could assist decision making in the ICU setting. In this work, we report on the development and validation of a dynamic mortality model specifically for critically ill COVID-19 patients and discuss its potential utility in the ICU.

Methods: We collected electronic medical record (EMR) data from 3222 ICU admissions with a COVID-19 infection from 25 different ICUs in the Netherlands. Read More

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