116,006 results match your criteria area january


Development and validation of a nomogram for further decision of radical surgery in pT1 colorectal cancer after local resection.

Int J Colorectal Dis 2021 Apr 17. Epub 2021 Apr 17.

Department of Gastrointestinal Surgery, Capital Medical University Affiliated Beijing Friendship Hospital, Beijing, People's Republic of China.

Purpose: The aim of this study was to develop and validate a nomogram to assist physicians making further decisions on the requirement of a radical surgery for T1 colorectal cancer (CRC) after local excision through preoperative prediction of lymph node metastasis (LNM).

Methods: A total of 141 T1 CRC patients were enrolled from January 2013 to August 2020. The independent predictive parameters were determined in multivariate analyses. Read More

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[Teledermatology in the Health Center West Area of Granada: From primary to specialized care].

Semergen 2021 Apr 13. Epub 2021 Apr 13.

Servicio de Dermatología, Hospital Universitario San Cecilio, Granada, España; Instituto biosanitario de Granada, Ibs, Granada, Spain. Electronic address:

Introduction: Teledermatology (TD) is a health tool based on the application of information and communication technologies (ICT) for the care of skin diseases at a distance, allowing a better connection between primary care professionals (PCP) and specialized care. The objective of this study was to analyze the characteristics of the teleconsultations made to our service in a period of 2years (January 1, 2018 to December 31, 2019).

Material And Methods: The data was obtained from a TD system with dermoscopy that allows teleconsultations to be carried out asynchronously. Read More

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Survival and predictors of mortality among severe acute malnourished under-five children admitted at Felege-Hiwot comprehensive specialized hospital, northwest, Ethiopia: a retrospective cohort study.

BMC Pediatr 2021 Apr 16;21(1):176. Epub 2021 Apr 16.

Department of Pediatrics and Child Health Nursing, College of Health Sciences, Debre Tabor University, P.O.Box:272, Debre Tabor, Ethiopia.

Background: Malnutrition is still a global public health problem contributing for under-five morbidity and mortality. The case is similar in Ethiopia in which severe acute malnutrition is the major contributor to mortality being an underlying cause for nearly 45% of under-five deaths. However, there is no recent evidence that shows the time to death and public health importance of oxygen saturation and chest in drawing in the study area. Read More

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Development and validation of a simple-to-use nomogram to predict the deterioration and survival of patients with COVID-19.

BMC Infect Dis 2021 Apr 16;21(1):356. Epub 2021 Apr 16.

Department of Neurosurgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, 350005, China.

Background: COVID-19 pandemic has forced physicians to quickly determine the patient's condition and choose treatment strategies. This study aimed to build and validate a simple tool that can quickly predict the deterioration and survival of COVID-19 patients.

Methods: A total of 351 COVID-19 patients admitted to the Third People's Hospital of Yichang between 9 January to 25 March 2020 were retrospectively analyzed. Read More

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SARS-CoV-2 infection in schools in a northern French city: a retrospective serological cohort study in an area of high transmission, France, January to April 2020.

Euro Surveill 2021 Apr;26(15)

Direction de la recherche médicale, Institut Pasteur, Paris, France.

BackgroundChildren's role in SARS-CoV-2 epidemiology remains unclear. We investigated an initially unnoticed SARS-CoV-2 outbreak linked to schools in northern France, beginning as early as mid-January 2020.AimsThis retrospective observational study documents the extent of SARS-CoV-2 transmission, linked to an affected high school (n = 664 participants) and primary schools (n = 1,340 study participants), in the context of unsuspected SARS-CoV-2 circulation and limited control measures. Read More

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Estimation of carbon dioxide emissions from the megafires of Australia in 2019-2020.

Sci Rep 2021 Apr 15;11(1):8267. Epub 2021 Apr 15.

Center for Global Environmental Research, Earth System Division, National Institute for Environmental Studies (NIES), 16-2 Onogawa, Tsukuba, Ibaraki, 305-8506, Japan.

Catastrophic fires occurred in Australia between 2019 and 2020. These fires burned vast areas and caused extensive damage to the environment and wildlife. In this study, we estimated the carbon dioxide (CO) emissions from these fires using a bottom-up method involving the improved burnt area approach and up-to-date remote sensing datasets to create monthly time series distribution maps for Australia from January 2019 to February 2020. Read More

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Do clinicians in areas of declining malaria transmission adhere to malaria diagnosis guidelines? A cross-sectional study from Kampala, Uganda.

Malar J 2021 Apr 15;20(1):187. Epub 2021 Apr 15.

Department of Internal Medicine, School of Medicine, Makerere University College of Health Science, P.O Box 7072, Kampala, Uganda.

Background: Uganda's clinical management guidelines recommend a malaria laboratory test in all patients presenting with fever (history of fever or an axillary temperature ≥ 37.5 °C), and only those with a positive test receive anti-malarial treatment. However, the current practice in areas with declining malaria transmission remains unknown. Read More

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Effects of air pollution, land-use type, and maternal mental health on child development in the first two years of life in the Greater Taipei area.

Environ Res 2021 Apr 12:111168. Epub 2021 Apr 12.

School of Public Health, College of Public Health, Taipei Medical University, Taipei, Taiwan; Neuroscience Research Center, Taipei Medical University, Taipei, Taiwan. Electronic address:

Introduction: Few studies have investigated the associations of child development with air pollution, land-use type, and maternal mental health simultaneously. Therefore, we evaluated the effect of exposure to air pollutants during several critical periods of life, with adjustment for land-use type and maternal mental status, on child development at 6, 12, and 24 months of age in the Greater Taipei area.

Methods: Participants were selected from an ongoing Taiwanese birth cohort study. Read More

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Risk Factors and Patterns of Locoregional Recurrence After Radical Nephrectomy for Locally Advanced Renal Cell Carcinoma.

Cancer Res Treat 2021 Apr 15. Epub 2021 Apr 15.

Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Purpose: We aimed to investigate the risk factors and patterns of locoregional recurrence (LRR) after radical nephrectomy (RN) in patients with locally advanced renal cell carcinoma (RCC).

Materials And Methods: We retrospectively analyzed 245 patients who underwent RN for non-metastatic pathologic T3-4 RCC from January 2006 to January 2016. We analyzed the risk factors associated with poor locoregional control using Cox regression. Read More

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Update: COVID-19 Pandemic-Associated Changes in Emergency Department Visits - United States, December 2020-January 2021.

MMWR Morb Mortal Wkly Rep 2021 Apr 16;70(15):552-556. Epub 2021 Apr 16.

During March 29-April 25, 2020, emergency department (ED) visits in the United States declined by 42% after the declaration of a national emergency for COVID-19 on March 13, 2020. Among children aged ≤10 years, ED visits declined by 72% compared with prepandemic levels (1). To assess the continued impact of the COVID-19 pandemic on EDs, CDC examined trends in visits since December 30, 2018, and compared the numbers and types of ED visits by patient demographic and geographic factors during a COVID-19 pandemic period (December 20, 2020-January 16, 2021) with a prepandemic period 1 year earlier (December 15, 2019-January 11, 2020). Read More

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Factors Associated with Participation in Elementary School-Based SARS-CoV-2 Testing - Salt Lake County, Utah, December 2020-January 2021.

MMWR Morb Mortal Wkly Rep 2021 Apr 16;70(15):557-559. Epub 2021 Apr 16.

During December 3, 2020-January 31, 2021, CDC, in collaboration with the University of Utah Health and Economic Recovery Outreach Project,* Utah Department of Health (UDOH), Salt Lake County Health Department, and one Salt Lake county school district, offered free, in-school, real-time reverse transcription-polymerase chain reaction (RT-PCR) saliva testing as part of a transmission investigation of SARS-CoV-2, the virus that causes COVID-19, in elementary school settings. School contacts of persons with laboratory-confirmed SARS-CoV-2 infection, including close contacts, were eligible to participate (1). Investigators approached parents or guardians of student contacts by telephone, and during January, using school phone lines to offer in-school specimen collection; the testing procedures were explained in the preferred language of the parent or guardian. Read More

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Source apportionment of PM at IMPROVE monitoring sites within and outside of marine vessel fuel sulfur emissions control areas.

J Air Waste Manag Assoc 2021 Apr 15. Epub 2021 Apr 15.

U.S. Environmental Protection Agency Region 10, Laboratory Services & Applied Science Division, Environmental Characterization Branch, 1200 Sixth Avenue, Suite 155 (Mailstop 14-D12), Seattle WA, 98101-3188, USA.

Fuel sulfur emissions control areas have been established in a few marine coastal regions to reduce environmental impacts from combustion of high sulfur residual fuel oil (RFO). For example, in August of 2012 the U.S. Read More

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Management of incontinence-associated dermatitis with topical antibiotics and antifungal medication.

J Wound Care 2021 Apr;30(Sup4):S24-S27

Division of Plastic Surgery, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Dalin, Taiwan.

Objective: The primary goals of managing incontinence-associated dermatitis (IAD) are to control the incontinence and to stop the progress of dermatitis. This study evaluated the effectiveness of using a combination of topical antibiotic and topical antifungal medication to manage IAD.

Method: Patients with grade 2 IAD treated with a combination of topical antibiotic Biomycin (CBC Biotechnological and Pharmaceutical, Taiwan) and antifungal clotrimazole (Sinphar Group, Taiwan) between January 2017 and January 2019 were included in this retrospective study. Read More

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Clinical implications of the invagination of an interwoven nitinol stent: a single-center retrospective analysis.

Cardiovasc Interv Ther 2021 Apr 15. Epub 2021 Apr 15.

Department of Cardiology, Tokyo Bay Medical Center, 3-4-32, Todaijima, Urayasu, Chiba, 279-0001, Japan.

Stent invagination (SIV) sometimes occurs during interwoven nitinol stent (IWS) placement due to its complex deployment system. It may cause stent malapposition and reduce the minimum stent area. However, the clinical implications of SIV remain unclear. Read More

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An Integrative Review of the Role of the Oral and Gut Microbiome in Oral Health Symptomatology During Cancer Therapy.

Oncol Nurs Forum 2021 05;48(3):317-331

University of Connecticut.

Problem Identification: Both chemotherapy and radiation therapy cause considerable symptom burden on patients' oral health, influencing nutritional status and quality of life. The role of the oral and gut microbiome in oral health alterations during cancer therapy is an emerging area of science in symptom management.

Literature Search: PubMed®, CINAHL®, and Scopus® were searched for articles published from January 2000 through July 2020. Read More

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[Comparison of effectiveness between plate and screw internal fixation in treatment of posterior malleolus fractures through posterolateral approach].

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2021 Apr;35(4):431-438

Guizhou Medical University, Guizhou Guiyang, 550004, P.R.China.

Objective: To compare the effectiveness of posterior malleolus fractures treated by plate and screw internal fixation through posterolateral approach.

Methods: The clinical data of 95 patients with posterior malleolus fractures who were admitted between January 2016 and December 2019 and met the selection criteria were retrospectively analysed. They were divided into plate group (44 cases, treated with posterolateral plate internal fixation) and screw group (51 cases, treated with posterolateral screw internal fixation) according to different treatment methods. Read More

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Employment of Artificial Intelligence Based on Routine Laboratory Results for the Early Diagnosis of Multiple Myeloma.

Front Oncol 2021 29;11:608191. Epub 2021 Mar 29.

Haematology Department of Shengjing Hospital, China Medical University, Shenyang, China.

Objective: In order to enhance the detection rate of multiple myeloma and execute an early and more precise disease management, an artificial intelligence assistant diagnosis system is developed.

Methods: 4,187 routine blood and biochemical examination records were collected from Shengjing Hospital affiliated to China Medical University from January 2010 to January 2020, which include 1,741 records of multiple myeloma (MM) and 2,446 records of non-myeloma (infectious diseases, rheumatic immune system diseases, hepatic diseases and renal diseases). The data set was split into training and test subsets with the ratio of 4:1 while connecting hemoglobin, serum creatinine, serum calcium, immunoglobulin (A, G and M), albumin, total protein, and the ratio of albumin to globulin data. Read More

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Assessment of delayed tuberculosis diagnosis preceding diagnostic confirmation among tuberculosis patients attending Isiolo County level four hospital, Kenya.

Pan Afr Med J 2021 18;38:51. Epub 2021 Jan 18.

Jomo Kenyatta University of Agriculture and Technology (JKUAT), College of Health Sciences (COHES), School of Public Health (SoPH), Nairobi, Kenya.

Introduction: delayed diagnosis of Mycobacterium tuberculosis infection leads to accelerated individual to individual transmission. This study evaluated this aspect of delayed diagnosis among patients visiting Isiolo level four hospital in northern Kenya.

Methods: this was a cross-sectional cohort study conducted during January, 2018-January, 2019 with systematically sampled 172 tuberculosis (TB) patients. Read More

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January 2021

An association between visceral or subcutaneous fat accumulation and diabetes mellitus among Japanese subjects.

Diabetol Metab Syndr 2021 Apr 14;13(1):44. Epub 2021 Apr 14.

Department of General Medicine, Juntendo University Faculty of Medicine, Hongo 2-1-1, Bunkyo-ku, Tokyo, 113-8421, Japan.

Background: The impact of subcutaneous fat accumulation remains controversial. This study assessed the association between visceral or subcutaneous fat area (VFA and SFA, respectively) and diabetes mellitus (DM) among Japanese subjects.

Methods: This was a cross-sectional study involving 1907 eligible participants (men, 1050; women, 857) who participated in a voluntary health check-up conducted at Juntendo University Hospital from January 2017 to December 2018, in Tokyo, Japan. Read More

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A modified anterior drawer test for anterior cruciate ligament ruptures.

J Orthop Surg Res 2021 Apr 14;16(1):260. Epub 2021 Apr 14.

Department of Orthopaedic Surgery, Huashan Hospital Fudan University, 12th Wulumuqi Middle Road, Jing'an District, Shanghai, China.

Objective: This study was aimed to utilize a modified anterior drawer test (MADT) to detect the anterior cruciate ligament (ACL) ruptures and investigate its accuracy compares with three traditional tests.

Methods: Four hundred patients were prospectively enrolled between January 2015 and September 2017 preoperatively to undergo knee arthroscopic surgeries. The MADT, anterior drawer test, Lachman test, and pivot shift test were used in the outpatient clinical setting and were compared statistically for their accuracy in terms of ACL ruptures, with arthroscopic findings as the gold standard. Read More

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Listeriosis - an analysis of human cases in the Czech Republic in 2008-2018.

Epidemiol Mikrobiol Imunol 2021 ;70(1):42-51

Aim: The aim of our work was to summarize the most important knowledge about listeriosis in humans and to analyse available epidemiological data on this disease in the Czech Republic in 2008-2018.

Methods: We conducted a literature search and descriptive epidemiological analysis of all human Listeria cases reported to the national surveillance system of infectious diseases (EpiDat until 2017, ISIN for 2018) in the Czech Republic in 2008-2018. For data management and analysis, MS Excel 2010 was used. Read More

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Atrial fibrillation and comorbidities: Clinical characteristics and antithrombotic treatment in GLORIA-AF.

PLoS One 2021 14;16(4):e0249524. Epub 2021 Apr 14.

Liverpool Centre for Cardiovascular Science, University of Liverpool and Liverpool Heart & Chest Hospital, Liverpool, United Kingdom.

Background: Patients with AF often have multimorbidity (the presence of ≥2 concomitant chronic conditions).

Objective: To describe baseline characteristics, patterns of antithrombotic therapy, and factors associated with oral anticoagulant (OAC) prescription in patients with AF and ≥2 concomitant, chronic, comorbid conditions.

Methods: Phase III of the GLORIA-AF Registry enrolled consecutive patients from January 2014 through December 2016 with recently diagnosed AF and CHA2DS2-VASc score ≥1 to assess the safety and effectiveness of antithrombotic treatment. Read More

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Does Bariatric Surgery Improve Faecal Incontinence? A Systematic Review and Meta-analysis.

Obes Surg 2021 Apr 14. Epub 2021 Apr 14.

Counties Manukau Health, 100 Hospital Road, Onehunga, Auckland, 2025, New Zealand.

Introduction: Obesity increases the risk of pelvic floor disorders in individuals with obesity, including faecal incontinence. Faecal incontinence (FI) is a condition with important clinical and psychosocial consequences. Though it is associated with obesity, the effect of bariatric surgery on the prevalence and severity of FI is not well reported. Read More

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Oral dryness and moisture degree at the lingual but not buccal mucosa predict prognosis in end-of-life cancer patients.

Support Care Cancer 2021 Apr 14. Epub 2021 Apr 14.

Division of Preventive Medicine, Clinical Research Institute, National Hospital Organization Kyoto Medical Center, Kyoto, Japan.

Purpose: The aim of this study is to investigate the association of oral dryness with overall survival and determine the threshold points of moisture degree for predicting 7-day survival in palliative care patients.

Methods: A total of 147 consecutive palliative care patients were included between January 2017 and November 2018. Oral dryness at the lingual and buccal mucosa was measured using an oral moisture-checking device. Read More

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Demographic, clinical, and anthropometric profiles and postoperative outcomes in patients with chronic limb threatening ischemia: A prospective descriptive study.

Niger J Clin Pract 2021 Apr;24(4):511-516

Department of Surgery, University of Cape Town, Groote Schuur Hospital, Vascular Surgery Unit, Cape Town, South Africa.

Background: Chronic limb-threatening ischemia (CLTI) is a complex disease caused by peripheral artery disease. It is associated with ischemic foot pain (rest pain) and tissue loss in the form of chronic nonhealing foot ulcers or gangrene. CLTI has a high short-term risk of limb amputations, postoperative sepsis, and cardiovascular-related events. Read More

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Preauricular Aging: A Three-Point Grading System to Guide Treatment in Facial Rejuvenation.

Aesthetic Plast Surg 2021 Apr 13. Epub 2021 Apr 13.

The Plastic Reconstructive Surgery Department, Tel Aviv Sourasky Medical Center, 6 Weizman Street, 642906, Tel Aviv, Israel.

Background: Aging affects the face in all its dimensions. However, more has been published about the improvement of the periocular, midface, and perioral aging changes. We believe the profile view, particularly the preauricular area, is of great value when assessing the need for facial contouring procedures, as well as their effectiveness. Read More

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Value of circulating tumor cells in the diagnosis and treatment of solitary pulmonary nodules.

Ann Transl Med 2021 Mar;9(6):501

Department of Thoracic Surgery, The First Affiliated Hospital of Soochow University, Suzhou, China.

Background: Lung cancer has become the most common malignant tumor worldwide, with the highest rates of morbidity and mortality. The detection of circulating tumor cells (CTCs) can be simple, rapid, and minimally invasive, thus endowing them with a high value in the diagnosis of malignant tumors. We aimed to explore the correlation between CTCs in peripheral blood and benign or malignant solitary pulmonary nodules (SPNs). Read More

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Intra-abdominal infection in acute pancreatitis in eastern China: microbiological features and a prediction model.

Ann Transl Med 2021 Mar;9(6):477

Department of Emergency, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Background: This study aimed to investigate the microbiol distribution of intra-abdominal infection in patients with acute pancreatitis, and to develop a reliable prediction model to guide the use of antibiotics.

Methods: Inpatient with acute pancreatitis between January 2015 and June 2020 were enrolled in the study. Participants were divided into the intra-abdominal infection group and non-infection group. Read More

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Risk factors for lymph node metastasis of the left recurrent laryngeal nerve in patients with esophageal squamous cell carcinoma.

Ann Transl Med 2021 Mar;9(6):476

Department of Minimally Invasive Esophagus Surgery, Key Laboratory of Prevention and Therapy, National Clinical Research Center of Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China.

Background: The factors for left recurrent laryngeal nerve (RLN) lymph node (LN) metastasis have important guiding significance for whether the left RLN LNs should be dissected in patients with esophageal squamous cell carcinoma (ESCC), but few studies are currently available. To analyze the risk factors of LN metastasis of the left RLN area and to assess which LNs should be dissected in ESCC.

Methods: This was a retrospective study of patients who underwent McKeown minimally invasive esophagectomy (MIE) (no neoadjuvant therapy) at Tianjin Medical University Cancer Institute and Hospital (from January 2016 to December 2019). Read More

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Repair of unilateral combined orbital floor and medial wall fracture using two titanium mesh plates: a modified technique.

Ann Transl Med 2021 Mar;9(6):463

Department of Ophthalmology, Tianjin Medical University General Hospital, Tianjin, China.

Background: Compared to isolated orbital wall fracture, combined orbital floor and medial wall fractures are more likely to be required surgical correction due to a higher possibility of complications. However, it remains a challenge to repair concomitant orbital fracture using a one-piece implant due to the complex anatomic structures of the orbit. Aiming to reduce surgical difficulties and enhance therapeutic effects, we repaired unilateral combined orbital floor and medial wall fractures using two separated modified titanium mesh plates in this study. Read More

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