Neuroimage 2021 Apr 18:118072. Epub 2021 Apr 18.
Department of Psychiatry, Boston University School of Medicine, Massachusetts, United States, 02118.; Boston Attention and Learning Laboratory, VA Boston Healthcare System, Massachusetts, United States, 02130.; National Center for PTSD, VA Boston Healthcare System, Massachusetts, United States, 02130.
In the search for brain markers of optimal attentional focus, the mainstream approach has been to first define attentional states based on behavioral performance, and to subsequently investigate "neural correlates" associated with these performance variations. However, this approach constrains the range of contexts in which attentional states can be operationalized by relying on overt behavior, and assumes a one-to-one correspondence between behavior and brain state. Here, we reversed the logic of these previous studies and sought to identify behaviorally-relevant brain states based solely on brain activity, agnostic to behavioral performance. Read More