16,202 results match your criteria apparent diffusion

Evaluation of amide proton transfer-weighted imaging for endometrial carcinoma histological features: a comparative study with diffusion kurtosis imaging.

Eur Radiol 2021 Apr 21. Epub 2021 Apr 21.

Department of Medical Imaging, Zhengzhou University People's Hospital & Henan Provincial People's Hospital, Zhengzhou, Henan, China.

Objectives: To investigate whether amide proton transfer-weighted imaging (APTWI) and diffusion kurtosis imaging (DKI) can be used to evaluate endometrial carcinoma (EC) in terms of clinical type, histological grade, subtype, and Ki-67 index.

Methods: Eighty-eight patients with EC underwent pelvic DKI and APTWI. The non-Gaussian diffusion coefficient (D), apparent kurtosis coefficient (K), and magnetization transfer ratio asymmetry (MTRasym (3. Read More

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Differentiating Liver Hemangioma from Metastatic Tumor Using T2-enhanced Spin-echo Imaging with a Time-reversed Gradient-echo Sequence in the Hepatobiliary Phase of Gadoxetic Acid-enhanced MR Imaging.

Magn Reson Med Sci 2021 Apr 20. Epub 2021 Apr 20.

Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University.

Purpose: To evaluate the utility of T2-enhanced spin-echo imaging using the time-reversed gradient echo sequence (T2FFE imaging) in the hepatobiliary phase (HBP) of gadoxetic acid-enhanced MRI (Gd-EOB-MRI) for differentiating hemangiomas from metastatic tumors.

Methods: A total of 61 patients with 133 liver lesions, including 37 hemangiomas and 96 metastatic tumors, were scanned by Gd-EOB-MRI. Four data sets were independently analyzed by two readers: (1) 3D fat-suppressed T2-weighted imaging (FS-T2WI) alone; (2) the combination of 3D FS-T2WI and T2FFE imaging in the HBP of Gd-EOB-MRI; (3) the combination of 3D FS-T2WI, diffusion-weighted imaging (DWI) with the b-value of 1000 s/mm and the apparent diffusion coefficient (ADC); and (4) a dynamic study of Gd-EOB-MRI. Read More

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Serial magnetic resonance imaging findings during severe attacks of familial hemiplegic migraine type 2: a case report.

BMC Neurol 2021 Apr 21;21(1):173. Epub 2021 Apr 21.

Department of Neurology, Neuroscience Institute, Geisinger Health System, 100 N Academy Ave, PA, Danville, USA.

Background: Hemiplegic migraines represent a heterogeneous disorder with various presentations. Hemiplegic migraines are classified as sporadic or familial based on the presence of family history, but both subtypes have an underlying genetic etiology. Mutations in the ATP1A2 gene are responsible for Familial Hemiplegic type 2 (FHM2) or the sporadic hemiplegic migraine (SHM) counterpart if there is no family history of the disorder. Read More

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Electrochemical reduction of O2 in Ca2+ containing DMSO - Role of roughness and single crystal structure.

ChemSusChem 2021 Apr 21. Epub 2021 Apr 21.

University of Bonn, Inst. f. Physikalische u.Theoret. Chemie, R�merstra�e 164, -Abteilung Elektrochemie-, 53117, Bonn, GERMANY.

This work compares the oxygen reduction reaction (ORR) in Ca2+ containing dimethyl sulfoxide (DMSO) at well-ordered and rough electrode surfaces using cyclic voltammetry, differential electrochemical mass spectrometry (DEMS), rotating ring disk electrode (RRDE) and atomic force microscopy (AFM). Slightly soluble CaO2 is the main product during early ORR on gold electrodes; after completion of a monolayer of CaO and/or CaO2, which is formed in parallel and in competition to the peroxide, only superoxide is formed. When the monolayer is completely closed on smooth annealed Au no further reduction occurs, whereas on rough Au a defect - rich layer allows for continuous formation of superoxide. Read More

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Penumbra quantification from MR SWI-DWI mismatch and its comparison with MR ASL PWI-DWI mismatch in patients with acute ischemic stroke.

NMR Biomed 2021 Apr 20:e4526. Epub 2021 Apr 20.

Centre for Biomedical Engineering, Indian Institute of Technology Delhi, New Delhi, India.

In acute-ischemic-stroke patients, penumbra assessment plays a significant role in treatment outcome. MR perfusion-weighted imaging (PWI) and diffusion-weighted imaging (DWI) mismatch ratio can provide penumbra assessment. Recently reported studies have shown the potential of susceptibility-weighted imaging (SWI) in the qualitative assessment of penumbra. Read More

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Low conductivity on electrical properties tomography demonstrates unique tumor habitats indicating progression in glioblastoma.

Eur Radiol 2021 Apr 20. Epub 2021 Apr 20.

Department of Tomographic Imaging, Philips Research Laboratories, Hamburg, Germany.

Objectives: Tissue conductivity measurements made with electrical properties tomography (EPT) can be used to define temporal changes in tissue habitats on longitudinal multiparametric MRI. We aimed to demonstrate the added insights for identifying tumor habitats obtained by including EPT with diffusion- and perfusion-weighted MRI, and to evaluate the use of these tumor habitats for determining tumor treatment response in post-treatment glioblastoma.

Methods: Tumor habitats were developed from EPT, diffusion-weighted, and perfusion-weighted MRI in 60 patients with glioblastoma who underwent concurrent chemoradiotherapy. Read More

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[Predictive value of combination of MRI tumor regression grade and apparent diffusion coefficient for pathological complete remission after neoadjuvant treatment of locally advanced rectal cancer].

Zhonghua Wei Chang Wai Ke Za Zhi 2021 Apr;24(4):359-365

Medical Imaging Center, the First Affiliate Hospital, Kunming Medical University, Kunming 650032, China.

Pelvic high-resolution magnetic resonance imaging (MRI) has now become a standard method for evaluating the efficacy of neoadjuvant treatment for locally advanced rectal cancer (LARC). However, this traditional morphological qualitative assessment method based on T2-weighted imaging (T2WI) is not effective in predicting pathological complete remission (pCR). The purpose of this study is to investigate whether combining the magnetic resonance tumor regression grade (mrTRG) with apparent diffusion coefficient (ADC) can improve diagnostic value for pCR after preoperative neoadjuvant chemoradiotherapy (nCRT) of LARC. Read More

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Diffusion-weighted magnetic resonance imaging of mandibular bone marrow: do apparent diffusion coefficient values of the cervical vertebrae and mandible correlate with age?

Oral Radiol 2021 Apr 20. Epub 2021 Apr 20.

Department of Stomatology, School of Dentistry, University of São Paulo, 2227 Lineu Prestes Avenue, São Paulo, SP, 05508-000, Brazil.

Objectives: The objective of this investigation was to assess the correlation between the mandible and cervical vertebrae bone marrow apparent diffusion coefficient (ADC), obtained by diffusion-weighted magnetic resonance imaging (DWI), with age; to verify the correlation between ADC values from the mandible and the cervical vertebrae; to describe and assess the differences between ADC values obtained from DWI examinations of distinct mandible areas as well as cervical vertebrae.

Methods: Thirty imaging examinations with DWI for that included the mandible and C1, C2, C3, and C4 vertebrae in the same examination were included. ADC values were collected from 7 distinct areas in the mandible and the cervical vertebrae. Read More

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Identifying lumbosacral plexus nerve root abnormalities in patients with sciatica using 3T readout-segmented echo-planar diffusion weighted MR neurography.

Insights Imaging 2021 Apr 20;12(1):54. Epub 2021 Apr 20.

Department of Radiology, Mater Misericordiae University Hospital, Eccles Street, Dublin7, Dublin, Ireland.

Objectives: To investigate the accuracy of Diffusion Weighted Imaging (DWI) using the Readout Segmentation of Long Variable Echo-trains (RESOLVE) sequence in detecting lumbosacral nerve abnormalities.

Methods: Following institutional ethics committee approval, patients with sciatica-type lower limb radicular symptoms (n = 110) were recruited and prospectively scanned using 3T MRI. Additional participants (n = 17) who underwent neurophysiological testing (EMG/NCV), were also prospectively studied. Read More

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Diffusion-weighted imaging in differentiating mid-course responders to chemotherapy for long-bone osteosarcoma compared to the histologic response: an update.

Pediatr Radiol 2021 Apr 20. Epub 2021 Apr 20.

Division of Pediatric Radiology, Hôpital Timone Enfants, Assistance publique - Hôpitaux de Marseille, 264 Rue Sainte Pierre, 13385, Marseille Cedex 05, France.

Background: Diffusion-weighted imaging (DWI) has been described to correlate with tumoural necrosis in response to preoperative chemotherapy for osteosarcoma.

Objective: To assess the accuracy of DWI in evaluating the response to neoadjuvant chemotherapy at the mid-course treatment of long-bone osteosarcoma and in predicting survival.

Materials And Methods: We conducted a prospective single-centre study over a continuous period of 11 years. Read More

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Prognostic Value of Apparent Diffusion Coefficient in Oropharyngeal Carcinoma.

Clin Neuroradiol 2021 Apr 20. Epub 2021 Apr 20.

Radiology, HUS Diagnostic Center, University of Helsinki and Helsinki University Hospital, Haartmaninkatu 4, 00029 HUS, Helsinki, Finland.

Purpose: To investigate clinical and radiological factors predicting worse outcome after (chemo)radiotherapy ([C]RT) in oropharyngeal squamous cell carcinoma (OPSCC) with a focus on apparent diffusion coefficient (ADC).

Methods: This retrospective study included 67 OPSCC patients, treated with (C)RT with curative intent and diagnosed during 2013-2017. Human papilloma virus (HPV) association was detected with p16 immunohistochemistry. Read More

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Nomogram development and validation to predict hepatocellular carcinoma tumor behavior by preoperative gadoxetic acid-enhanced MRI.

Eur Radiol 2021 Apr 20. Epub 2021 Apr 20.

Department of Radiology, The First Affiliated Hospital, Sun Yat-sen University, 58 Zhongshan Road 2, Guangzhou, 510080, China.

Objectives: Pretreatment evaluation of tumor biology and microenvironment is important to predict prognosis and plan treatment. We aimed to develop nomograms based on gadoxetic acid-enhanced MRI to predict microvascular invasion (MVI), tumor differentiation, and immunoscore.

Methods: This retrospective study included 273 patients with HCC who underwent preoperative gadoxetic acid-enhanced MRI. Read More

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Tissue clearing techniques for three-dimensional optical imaging of intact human prostate and correlations with multi-parametric MRI.

Prostate 2021 Apr 20. Epub 2021 Apr 20.

Medical Artificial Intelligence Laboratory Program, The University of Hong Kong, Hong Kong, Hong Kong SAR.

Background: Tissue clearing technologies have enabled remarkable advancements for in situ characterization of tissues and exploration of the three-dimensional (3D) relationships between cells, however, these studies have predominantly been performed in non-human tissues and correlative assessment with clinical imaging has yet to be explored. We sought to evaluate the feasibility of tissue clearing technologies for 3D imaging of intact human prostate and the mapping of structurally and molecularly preserved pathology data with multi-parametric volumetric MR imaging (mpMRI).

Methods: Whole-mount prostates were processed with either hydrogel-based CLARITY or solvent-based iDISCO. Read More

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Stem and root nodules on the tropical wetland legume Aeschynomene fluminensis.

New Phytol 1995 Aug;130(4):531-544

CNPAB/EMBRAPA, Seropédica, Itaguai, RJ 23851-970, Brazil.

Aeschynomene fluminensis Veil., originally obtained from flooded areas of the Pantanal Matogrossense region of Brazil, was grown under stem-flooded or non-flooded conditions for 70 d after inoculation with isolates of photosynthetic stem nodule rhizobia obtained from native A. fluminensis. Read More

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Carbohydrate transport in discs of storage parenchyma of celery petioles: 2. Uptake of mannitol.

Felix Keller

New Phytol 1991 Mar;117(3):423-429

Institute of Plant Biology, University of Zürich, Zollikerstr. 107 CH-8008 Zürich, Switzerland.

The sugar alcohol mannitol is, together with glucose and fructose, the main soluble carbohydrate of celery petioles. It is accumulated in the storage parenchyma of mature petioles and remobilized during senescence. The mechanisms of mannitol uptake into discs isolated from petiole parenchyma was studied. Read More

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Carbohydrate transport in discs of storage parenchyma of celery petioles: I. Uptake of glucose and fructose.

New Phytol 1991 Mar;117(3):413-422

Institute of Plant Biology, University of Zürich, Zollikerstr. 107 CH-8008 Zürich, Switzerland.

Petioles of celery leaves function successively as net importing (sink) and net exporting (source) organs during ontogeny. The parenchyma of these petioles is the main store for large amounts of D-glucose, D-fructose and mannitol. The mechanism of uptake of glucose and fructose into discs isolated from storage parenchyma of celery petioles was investigated. Read More

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Investigating DWI changes in white matter of meningioma patients treated with proton therapy.

Phys Med 2021 Apr 16;84:72-79. Epub 2021 Apr 16.

Department of Electronics, Information and Bioengineering, Politecnico di Milano, Piazza Leonardo da Vinci 32, 20133 Milan, Italy. Electronic address:

Purpose: To evaluate changes in diffusion and perfusion-related properties of white matter (WM) induced by proton therapy, which is capable of a greater dose sparing to organs at risk with respect to conventional X-ray radiotherapy, and to eventually expose early manifestations of delayed neuro-toxicities.

Methods: Apparent diffusion coefficient (ADC) and IVIM parameters (D, D* and f) were estimated from diffusion-weighted MRI (DWI) in 46 patients affected by meningioma and treated with proton therapy. The impact on changes in diffusion and perfusion-related WM properties of dose and time, as well as the influence of demographic and pre-treatment clinical information, were investigated through linear mixed-effects models. Read More

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Intermuscular Fat Content in Young Chinese Men With Newly Diagnosed Type 2 Diabetes: Based on MR mDIXON-Quant Quantitative Technique.

Front Endocrinol (Lausanne) 2021 30;12:536018. Epub 2021 Mar 30.

Department of Radiology, Shengjing Hospital of China Medical University, Shenyang, China.

Objective: Skeletal muscle fat content is one of the important contributors to insulin resistance (IR), but its diagnostic value remains unknown, especially in the Chinese population. Therefore, we aimed to analyze differences in skeletal muscle fat content and various functional MRI parameters between diabetic patients and control subjects to evaluate the early indicators of diabetes. In addition, we aimed to investigate the associations among skeletal muscle fat content, magnetic resonance parameters of skeletal muscle function and IR in type 2 diabetic patients and control subjects. Read More

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Role of diffusion-weighted MRI in differentiating between benign and malignant bone lesions: a prospective study.

Clin Radiol 2021 Apr 14. Epub 2021 Apr 14.

Radio-diagnosis Department, Faculty of Medicine, South Valley University, Qena, Egypt.

Aim: To evaluate the ability of diffusion-weighted magnetic resonance imaging (DW-MRI) to differentiate between benign and malignant bony tumours.

Materials And Methods: This prospective study was conducted from October, 2018 to December, 2019. The study included 62 patients (37 male and 25 female) with clinically suspected bony lesions referred to the Radiology Department. Read More

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MRI diffusion phantoms: ADC and relaxometric measurement comparisons between polyacrylamide and agarose gels.

Eur J Radiol 2021 Apr 8;139:109696. Epub 2021 Apr 8.

Department of Medical Physics, University of Crete, Heraklion, Crete, Greece; Computational BioMedicine Laboratory, Institute of Computer Science, Foundation for Research and Technology-Hellas (FORTH), Heraklion, Crete, Greece. Electronic address:

Purpose: The aim of this study is to compare polyacrylamide and agarose gels, as components of a simple MRI phantom, for the measurements of Apparent Diffusion Coefficient (ADC), T1 and T2 relaxation times.

Materials And Methods: Five (5) test tubes with polyacrylamide gels of different monomer concentrations and six (6) test tubes of different agarose gel concentrations were used as a phantom for ADC, T1 and T2 measurements, which were expressed as 2D color parametric maps, on a 1.5 T clinical MRI system. Read More

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SARS-CoV-2-associated first episode of acute mania with psychotic features.

J Clin Neurosci 2021 May 1;87:29-31. Epub 2021 Mar 1.

Department of Psychiatry, Bakirkoy Prof Mazhar Osman Training and Research Hospital for Psychiatry, Neurology, and Neurosurgery, Istanbul, Turkey. Electronic address:

Despite neuropsychiatric outcomes of SARS-CoV-2 infection are now under close scrutiny, psychoneuroimmunological characteristics of COVID-19 and precise pathophysiology of neuropsychiatric manifestations of the infection are still obscure. Moreover, there still exists a shortfall in demonstrating specific clinical manifestations of the brain involvement of the virus. Here, we presented a 33-year-old female patient with COVID-19, reporting acute-onset paranoid delusions symptoms, insomnia and irritability. Read More

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Prognostic prediction of resectable colorectal liver metastasis using the apparent diffusion coefficient from diffusion-weighted magnetic resonance imaging.

Ann Gastroenterol Surg 2021 Mar 5;5(2):252-258. Epub 2020 Oct 5.

Department of Surgery Institute of Biomedical Sciences University of Tokushima Tokushima Japan.

Aim: Diffusion-weighted magnetic resonance imaging (DWI-MRI) is used to predict tumor malignancy. Here we explored the role of apparent diffusion coefficient (ADC) values in the treatment of patients with resectable colorectal liver metastasis (CRLM).

Methods: Magnetic resonance imaging (MRI) scans were conducted using a Signa HDe or Signa Explorer 1. Read More

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Differentiation of brain metastases from small and non-small lung cancers using apparent diffusion coefficient (ADC) maps.

BMC Med Imaging 2021 Apr 15;21(1):70. Epub 2021 Apr 15.

Department of Diagnostic and Interventional Neuroradiology, Georg-August-University Göttingen, Robert-Koch-Str. 40, 37075, Göttingen, Germany.

Background: Brain metastases are particularly common in patients with small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC), with NSCLC showing a less  aggressive clinical course and lower chemo- and radio sensitivity compared to SCLC. Early adequate therapy is highly desirable and depends on a reliable classification of tumor type. The apparent diffusion coefficient is a noninvasive neuroimaging marker with the potential to differentiate between major histological subtypes. Read More

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Non-invasive assessment of heterogeneity of gliomas using diffusion and perfusion MRI: correlation with spatially co-registered PET.

Acta Radiol 2021 Apr 15:2841851211006913. Epub 2021 Apr 15.

Department of Nuclear Medicine, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, PR China.

Background: Heterogeneity of gliomas challenges the neuronavigated biopsy and oncological therapy. Diffusion and perfusion magnetic resonance imaging (MRI) can reveal the cellular and hemodynamic heterogeneity of tumors. Integrated positron emission tomography (PET)/MRI is expected to be a non-invasive imaging approach to characterizing glioma. Read More

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Diffusion weighted imaging in high-grade gliomas: A histogram-based analysis of apparent diffusion coefficient profile.

PLoS One 2021 15;16(4):e0249878. Epub 2021 Apr 15.

Department for Radiology, University Hospital Halle (Saale), Halle (Saale), Germany.

Purpose: Glioblastoma and anaplastic astrocytoma represent the most commonly encountered high-grade-glioma (HGG) in adults. Although both neoplasms are very distinct entities in context of epidemiology, clinical course and prognosis, their appearance in conventional magnetic resonance imaging (MRI) is very similar. In search for additional information aiding the distinction of potentially confusable neoplasms, histogram analysis of apparent diffusion coefficient (ADC) maps recently proved to be auxiliary in a number of entities. Read More

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Effect of External Surface Diffusion Barriers on Pt/Beta Catalyzed Isomerization of n-Pentane.

Angew Chem Int Ed Engl 2021 Apr 15. Epub 2021 Apr 15.

East China University of Science and Technology, School of Chemical Engineering, CHINA.

Zeolite crystals contain transport barriers on their external surface that hinder molecular uptake and processes that depend on it, such as catalysis and separations. However, the potentially dominant role of surface barriers in such processes is only emerging. In this work, we have developed a generalizable strategy to quantify the effect of surface barriers on zeolite catalysis. Read More

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Detection of Contralateral Breast Cancer Using Diffusion-Weighted Magnetic Resonance Imaging in Women with Newly Diagnosed Breast Cancer: Comparison with Combined Mammography and Whole-Breast Ultrasound.

Korean J Radiol 2021 Apr 1. Epub 2021 Apr 1.

Department of Radiology, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, Korea.

Objective: To compare the screening performance of diffusion-weighted (DW) MRI and combined mammography and ultrasound (US) in detecting clinically occult contralateral breast cancer in women with newly diagnosed breast cancer.

Materials And Methods: Between January 2017 and July 2018, 1148 women (mean age ± standard deviation, 53.2 ± 10. Read More

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Diagnostic nomogram based on intralesional and perilesional radiomics features and clinical factors of clinically significant prostate cancer.

J Magn Reson Imaging 2021 May;53(5):1550-1558

Department of Radiology, Yantai Yuhuangding Hospital, Qingdao University, Yantai, China.

Previous studies on the value of radiomics for diagnosing clinically significant prostate cancer (csPCa) only utilized intralesional features. However, the role of tumor microenvironment is important in tumor generation and progression. The aim of this study is to build and validate a nomogram based on perilesional and intralesional radiomics features and clinical factors for csPCa. Read More

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Quantitative assessment of age-related changes in the mandibular bone marrow using apparent coefficient value.

Oral Radiol 2021 Apr 13. Epub 2021 Apr 13.

Department of Radiology, Nihon University School of Dentistry At Matsudo, 2-870-1 Sakaecho-Nishi, Matsudo, Chiba, 271-8587, Japan.

Purpose: The purpose of this study was to investigate the age-related changes in apparent diffusion coefficient (ADC) values of the mandibular bone marrow using diffusion-weighted imaging (DWI).

Materials And Methods: This retrospective cohort study comprised all patients who underwent pantomography and magnetic resonance imaging (MRI) between April 2018 and November 2020 at our institution. A total of 351 participants (140 men, 211 women), aged 15-89 years (mean age 46. Read More

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A multiparametric MRI-based CAD system for accurate diagnosis of bladder cancer staging.

Comput Med Imaging Graph 2021 Mar 31;90:101911. Epub 2021 Mar 31.

Bioengineering Department, University of Louisville, Louisville, KY, USA. Electronic address:

Appropriate treatment of bladder cancer (BC) is widely based on accurate and early BC staging. In this paper, a multiparametric computer-aided diagnostic (MP-CAD) system is developed to differentiate between BC staging, especially T1 and T2 stages, using T2-weighted (T2W) magnetic resonance imaging (MRI) and diffusion-weighted (DW) MRI. Our framework starts with the segmentation of the bladder wall (BW) and localization of the whole BC volume (V) and its extent inside the wall (V). Read More

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