16,557 results match your criteria aortic diameter


Distinct Effects of Heparin and Interleukin-4 Functionalization on Macrophage Polarization and In Situ Arterial Tissue Regeneration Using Resorbable Supramolecular Vascular Grafts in Rats.

Adv Healthc Mater 2021 Sep 14:e2101103. Epub 2021 Sep 14.

Department of Biomedical Engineering and Institute for Complex Molecular Systems (ICMS), Eindhoven University of Technology, Eindhoven, 5600 MB, The Netherlands.

Two of the greatest challenges for successful application of small-diameter in situ tissue-engineered vascular grafts are 1) preventing thrombus formation and 2) harnessing the inflammatory response to the graft to guide functional tissue regeneration. This study evaluates the in vivo performance of electrospun resorbable elastomeric vascular grafts, dual-functionalized with anti-thrombogenic heparin (hep) and anti-inflammatory interleukin 4 (IL-4) using a supramolecular approach. The regenerative capacity of IL-4/hep, hep-only, and bare grafts is investigated as interposition graft in the rat abdominal aorta, with follow-up at key timepoints in the healing cascade (1, 3, 7 days, and 3 months). Read More

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September 2021

-Adventitial delivery of smooth muscle cells in porous collagen scaffolds for treatment of experimental abdominal aortic aneurysm.

Biomater Sci 2021 Sep 15. Epub 2021 Sep 15.

Veterans Affairs Palo Alto Health Care System, Palo Alto, CA, USA.

Abdominal aortic aneurysm (AAA) is associated with the loss of vascular smooth muscle cells (SMCs) within the vessel wall. Direct delivery of therapeutic cells is challenging due to impaired mechanical integrity of the vessel wall. We hypothesized that porous collagen scaffolds can be an effective vehicle for the delivery of human-derived SMCs to the site of AAA. Read More

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September 2021

Endograft apposition and infrarenal neck enlargement after endovascular aortic aneurysm repair.

J Cardiovasc Surg (Torino) 2021 Sep 14. Epub 2021 Sep 14.

Department of Surgery, Division of Vascular Surgery, University Medical Center Groningen, Groningen, The Netherlands.

Background: Sufficient apposition and oversizing of the endograft in the aortic neck are both essential for durable endovascular aneurysm repair (EVAR). These measures are however not regularly stated on post-EVAR computed tomography angiography (CTA) scan reports. In this study endograft apposition and neck enlargement (NE) after EVAR with an Endurant II(s) endograft were analyzed and associated with supra- and infrarenal aortic neck morphology. Read More

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September 2021

Factors affecting vitamin D status in outpatients with abdominal aortic aneurysm and peripheral artery disease- a single centre study.

Nutr Metab Cardiovasc Dis 2021 Jul 24. Epub 2021 Jul 24.

Pathophysiology Unit, Department of Pathophysiology, Faculty of Medical Sciences in Katowice, The Medical University of Silesia in Katowice, Poland; Department of Internal Medicine and Oncological Chemotherapy, Medical Faculty in Katowice, Medical University of Silesia, Katowice, Poland.

Background And Aims: Vitamin D (VD) deficiency is considered an important risk factor for the development of atherosclerosis and aortic aneurysms. The deficiency is claimed to enhance degeneration and remodeling of collagen and elastin fibers in the artery wall, leading to its weakening and progressive dilatation. This study aimed to assess vitamin D status, in outpatients with abdominal aneurysms (AAA) and peripheral artery disease (PAD) not treated with VD, and factors affecting serum 25-OH-D levels. Read More

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Pre-surgical and Post-surgical Aortic Aneurysm Maximum Diameter Measurement: Full Automation by Artificial Intelligence.

Eur J Vasc Endovasc Surg 2021 Sep 10. Epub 2021 Sep 10.

Aortic Centre, Hôpital Marie Lannelongue, Groupe Hospitalier Paris Saint Joseph, Université Paris Saclay, Paris, France. Electronic address:

Objective: The aim of this study was to evaluate an automatic, deep learning based method (Augmented Radiology for Vascular Aneurysm [ARVA]), to detect and assess maximum aortic diameter, providing cross sectional outer to outer aortic wall measurements.

Methods: Accurate external aortic wall diameter measurement is performed along the entire aorta, from the ascending aorta to the iliac bifurcations, on both pre- and post-operative contrast enhanced computed tomography angiography (CTA) scans. A training database of 489 CTAs was used to train a pipeline of neural networks for automatic external aortic wall measurements. Read More

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September 2021

[Hybrid repair of aortic arch aneurysm].

Ann Cardiol Angeiol (Paris) 2021 Sep 10. Epub 2021 Sep 10.

University of Tunis El Manar, Faculty of Medicine of Tunis, La Rabta Hospital, Cardiovascular surgery Department, Tunis, Tunisia.

Background: The management of aortic arch aneurysms is challenging. If conventional surgery cannot be performed in high risk patients, endovascular treatment is confronted to the problem of endoleaks at long term. However, the hybrid repair combining a first surgical step and a second endovascular step is a new technique recently introduced in the therapeutic alternatives of aortic arch aneurysm but its long-term results are not well known. Read More

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September 2021

Reversal of elastase-induced abdominal aortic aneurysm following the delivery of nanoparticle-based pentagalloyl glucose (PGG) is associated with reduced inflammatory and immune markers.

Eur J Pharmacol 2021 Sep 10:174487. Epub 2021 Sep 10.

Department of Bioengineering, Clemson University, SC, 29634, USA. Electronic address:

Objective: An Abdominal aortic aneurysm (AAA), a deadly disease in elderly population, is featured by expansion of aortic diameter, degradation and weakening of vasculature. Its common and significant characteristics are disarray and inflammation in vasculature. We tested the hypothesis that the reversal of abdominal aortic aneurysm by pentagalloyl glucose-loaded nanoparticles (PGG-NPs) therapy that targets degraded elastin suppresses inflammatory and immune markers to ameliorate the pathophysiology of the disease in advance stage aneurysm in a porcine pancreatic elastase (PPE)-induced mouse model of AAA. Read More

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September 2021

Comparison of two techniques (in vivo and ex-vivo) for evaluating the elastic properties of the ascending aorta: Prospective cohort study.

PLoS One 2021 13;16(9):e0256278. Epub 2021 Sep 13.

Department of Cardio-vascular and Thoracic Surgery, Dijon University Hospital, Dijon, France.

Introduction: Aneurysms of the ascending aorta (AA) correspond to a dilatation of the ascending aorta that progressively evolves over several years. The main complication of aneurysms of the ascending aorta is type A aortic dissection, which is associated with very high rates of morbidity and mortality. Prophylactic ascending aorta replacement guidelines are currently based on maximal AA diameter. Read More

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September 2021

High prevalence of extrarenal artery involvement in children with fibromuscular dysplasia - a single-center experience.

J Hypertens 2021 Aug 12. Epub 2021 Aug 12.

Department of Nephrology, Kidney Transplantation and Hypertension.

Background: Although the clinical presentation of fibromuscular dysplasia (FMD) and its generalized character has been previously described in adults, data on FMD in children are limited.

Method: In this study, we aimed to assess visceral artery involvement in pediatric FMD patients with documented renal artery stenosis (RAS) and renovascular hypertension (RVH) in comparison with healthy individuals. We retrospectively analyzed the results of angiographic studies of 16 patients with a median age of 13. Read More

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: Factors Affecting the Radial Stiffness of Thoracic Aorta Stent-Grafts.

Sovrem Tekhnologii Med 2021 28;13(1):17-25. Epub 2021 Feb 28.

Professor, Director, Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation, 15 Rechkunovskaya St., Novosibirsk, 630055, Russia.

was to study the factors influencing the radial stiffness of the thoracic aorta stent-grafts with the stent elements made of nitinol tubes by laser cutting and thermal shape setting.

Materials And Methods: The work used stent elements made by different technologies by two different manufacturers from a nitinol tube with a wall thickness of 0.5 mm (E1) and 0. Read More

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February 2021

Geometric, Biomechanic and Haemodynamic Aortic Abnormalities Assessed by 4D Flow Cardiovascular Magnetic Resonance in Patients Treated by TEVAR Following Blunt Traumatic Thoracic Aortic Injury.

Eur J Vasc Endovasc Surg 2021 Sep 9. Epub 2021 Sep 9.

Vascular and Endovascular Surgery, Hospital Universitari Vall d'Hebron, Barcelona, Spain; Departament de Cirurgia. Universitat Autònoma de Barcelona (UAB), Bellaterra, Spain.

Objective: Thoracic endovascular aortic repair (TEVAR) is widely used for the treatment of patients with blunt traumatic thoracic aortic injury (BTAI). However, aortic haemodynamic and biomechanical implications of this intervention are poorly investigated. This study aimed to assess whether patients treated by TEVAR following BTAI have thoracic aortic abnormalities in geometry, stiffness, and haemodynamics. Read More

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September 2021

Value of near-infrared spectroscopy in monitoring intestinal tissue oxygen saturation in preterm infants with hemodynamically significant patent ductus arteriosus: a prospective research.

Zhongguo Dang Dai Er Ke Za Zhi 2021 Aug;23(8):821-827

Department of Neonatology, Longgang District Central Hospital of Shenzhen, Shenzhen, Guangdong 518116, China.

Objectives: To study the change in regional oxygen saturation (rSO) of intestinal tissue in preterm infants with hemodynamically significant patent ductus arteriosus (hsPDA) by near-infrared spectroscopy, and the clinical significance of the change in intestinal oxygen level in preterm infants with hsPDA.

Methods: The preterm infants with patent ductus arteriosus (PDA) who had gestational age <32 weeks and/or birth weight <1 500 g were prospectively enrolled, who were admitted to the Department of Neonatology, Shenzhen Longgang Central Hospital from October 2017 to October 2020.According to the diagnostic criteria for hsPDA, the preterm infants with patent ductus arteriosus (PDA) were divided into two groups: hsPDA and non-hsPDA. Read More

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Long-term Implications of Elective EVAR That is Non-compliant with Clinical Practice Guideline Diameter Thresholds.

J Vasc Surg 2021 Sep 8. Epub 2021 Sep 8.

Divisions of Vascular and Endovascular Surgery, Beth Israel Deaconess Medical Center, Boston MA. Electronic address:

Objective: Compliance with SVS AAA clinical practice guideline (CPG) diameter thresholds is variable for EVAR. In order to evaluate the implications and appropriateness of repairs that are non-compliant with current guidelines, we investigated the long-term outcomes, adherence to imaging follow-up, and associated healthcare costs in patients undergoing EVAR for AAA who do or do not meet recommended diameter thresholds.

Methods: All patients receiving elective EVAR from 2003-2016 in the SVS-VQI with linked Medicare claims were reviewed. Read More

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September 2021

Geometric and biomechanical modeling aided by machine learning improves the prediction of growth and rupture of small abdominal aortic aneurysms.

Sci Rep 2021 Sep 10;11(1):18040. Epub 2021 Sep 10.

Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.

It remains difficult to predict when which patients with abdominal aortic aneurysm (AAA) will require surgery. The aim was to study the accuracy of geometric and biomechanical analysis of small AAAs to predict reaching the threshold for surgery, diameter growth rate and rupture or symptomatic aneurysm. 189 patients with AAAs of diameters 40-50 mm were included, 161 had undergone two CTAs. Read More

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September 2021

Echocardiographic evaluation of deformity and enlargement of the canine mitral valve annulus associated with myxomatous degenerative mitral valve disease.

J Vet Cardiol 2021 Aug 20;37:8-17. Epub 2021 Aug 20.

Joint Graduate School of Veterinary Medicine, Kagoshima University, 1-21-24 Korimoto, Kagoshima, 8900065, Japan.

Introduction/objectives: Quantitative evaluation of the morphology of the mitral valve annulus (MVA) in dogs with myxomatous mitral valve disease (MMVD) may improve the techniques of mitral valve plasty. This study aimed to compare the MVA morphology on echocardiography in normal dogs and dogs with MMVD and to compare the echocardiographic and intraoperative measurements of the MVA in dogs with MMVD.

Animals, Materials And Methods: The study population comprised 59 healthy dogs (control group) and 371 dogs with MMVD (MMVD group). Read More

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Sex Specific Criteria for Repair Should be Utilized in Patients Undergoing Aortic Aneurysm Repair.

J Vasc Surg 2021 Sep 7. Epub 2021 Sep 7.

The Divisions of Vascular and Endovascular Surgery, Beth Israel Deaconess Medical Center, Boston, MA. Electronic address:

Objective: Female patients are more likely to undergo repair of intact and ruptured abdominal aortic aneurysm (AAA) at smaller aortic diameter compared with male patients. By adjusting for inherent anatomic differences between sexes, aortic size index (ASI) and aortic height index (AHI) may provide an additional method for guiding treatment. We therefore analyzed sex-specific criteria for AAA repair using aortic diameter, ASI, and AHI. Read More

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September 2021

Sarcopenia Predicts Long Term Survival in Patients with Thoracoabdominal Aortic Aneurysms Undergoing Operative and Non-Operative Management.

J Vasc Surg 2021 Sep 7. Epub 2021 Sep 7.

Department of Surgery, Division of Vascular Surgery, University of Washington, Seattle, Washington 98104. Electronic address:

Objectives: Sarcopenia, defined as a loss of muscle mass or poor muscle quality, is a syndrome associated with poor surgical outcomes. The prognostic value of sarcopenia in patients with thoracoabdominal aortic aneurysms (TAAA) is unknown. This study was designed to define sarcopenia in this patient population and assess its impact on survival among patients who underwent operative and non-operative management of TAAA. Read More

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September 2021

Predictors of Sac Regression after Fenestrated Endovascular Aneurysm Repair.

J Vasc Surg 2021 Sep 7. Epub 2021 Sep 7.

Department of Surgery, Division of Vascular and Endovascular Surgery, Stanford University School of Medicine. Electronic address:

Objective: Aneurysm sac regression after standard endovascular aortic repair is associated with improved outcomes, but similar data are limited after fenestrated endovascular aortic repair (FEVAR). We sought to evaluate sac regression after FEVAR, and identify any predictors of this favorable outcome.

Methods: Patients undergoing elective FEVAR using the commercially available Zenith Fenestrated device (ZFEN; Cook Medical, Bloomington, IN) from 2012 to 2018 at a single institution were retrospectively reviewed. Read More

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September 2021

IMPACT OF THORACIC ENDOVASCULAR AORTIC REPAIR TIMING ON AORTIC REMODELING IN ACUTE TYPE B AORTIC INTRAMURAL HEMATOMA.

J Vasc Surg 2021 Sep 7. Epub 2021 Sep 7.

Eastern Virginia Medical School, Division of Vascular Surgery, Norfolk, VA. Electronic address:

Introduction: Thoracic endovascular aortic repair (TEVAR) is increasingly utilized in the management of acute type B aortic intramural hematoma (TBIMH). Optimal timing for intervention has not been described. The aim of this study was to evaluate TEVAR timing on post-operative aortic remodeling. Read More

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September 2021

Increased Mobility of the Atrial Septum in Aortic Root Dilation: An Observational Study on Transesophageal Echocardiography.

Front Physiol 2021 24;12:701399. Epub 2021 Aug 24.

Graduate Studies Program in Cardiology, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.

There is a growing interest in the relationship between atrial septal anatomy and cardioembolic stroke. Anecdotal reports suggest that the enlargement of the aortic root could interfere with atrial septal mobility (ASM). We sought to investigate the association between ASM and aortic root dilation. Read More

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Towards Endovascular Treatment of Type A Aortic Dissection with Smaller Landing Zones and More Patient Eligibility.

J Vasc Surg 2021 Sep 6. Epub 2021 Sep 6.

Department of Surgery, University of California San Francisco, San Francisco, CA, United States.

Objective: Type A or ascending aortic dissection is an acute life-threatening condition with high morbidity and mortality. Open surgery remains standard-of-care. Development of minimally invasive endografts for Type A aortic dissection (TAAD) will require detailed understanding of dissection and aortic root anatomy to determine patient eligibility and optimal device specifications. Read More

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September 2021

The Natural History, Growth Rates and Treatment of Popliteal Artery Aneurysms.

J Vasc Surg 2021 Sep 6. Epub 2021 Sep 6.

Department of Molecular Medicine and Surgery, Karolinska Institutet; Department of Vascular Surgery, Karolinska University Hospital, Stockholm, Sweden.

Introduction: The natural history of a cohort of patients under surveillance with popliteal artery aneurysms (PAA) is not well described. There is a prevailing uncertainty regarding optimal surveillance strategies and timing of treatment. The primary aim was to describe the care trajectory of all patients with PAA identified in two tertiary vascular centers, both in surveillance and eventually treated. Read More

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September 2021

A New Minimally Invasive Method of Transverse Aortic Constriction in Mice.

J Cardiovasc Transl Res 2021 Sep 8. Epub 2021 Sep 8.

Department of Cardiac Surgery, The First Affiliated Hospital of Sun Yat-Sen University, 58 Zhongshan II Road, Guangzhou, 510080, Guangdong Province, China.

Transverse aortic constriction (TAC) in mice is the most popular model to mimic pressure overload heart disease. In this study, we developed a convenient, quick, and less invasive new TAC mice model. Briefly, after anesthetization, endotracheal intubation was then performed, and the endotracheal tube was connected to a ventilator. Read More

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September 2021

Prominent prolapsing Chiari network: presentation and prognosis in paediatric patients.

Cardiol Young 2021 Sep 8:1-6. Epub 2021 Sep 8.

Pediatric Cardiology Division, Department of Pediatrics, University of Florida- Jacksonville, Jacksonville, FL, USA.

Chiari network is an infrequently visualized web-like structure in the right atrium that is usually thin and small. Rarely, it can be prominent and elongated with protrusion into the right ventricle during diastole and complications have been reported. Thirty-eight patients (median age 2. Read More

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September 2021

Sex-specific normal values and determinants of infrarenal abdominal aortic diameter among non-aneurysmal elderly population.

Sci Rep 2021 Sep 7;11(1):17762. Epub 2021 Sep 7.

Department of Epidemiology, Erasmus University Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.

To establish age- and sex-specific distribution of the infrarenal abdominal aortic diameters (IAD) among non-aneurysmal elderly population and to investigate the associations between traditional cardiovascular risk factors and IAD in men and women. We included 4032 participants (mean age 67.2 years; 60. Read More

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September 2021

Aortic Geometric Alteration Associated With Acute Type B Aortic Dissection: Angulation, Tortuosity, and Arch Type.

Front Physiol 2021 20;12:708651. Epub 2021 Aug 20.

Department of Vascular Surgery, The Second Xiangya Hospital, Central South University, Changsha, China.

Acute type B aortic dissection is a highly serious aortic pathology. Aortic geometric parameters may be useful variables related to the occurrence of acute type B aortic dissection (aTBAD). The aim of the study is to delineate the alteration in aortic geometric parameters and analyze the specific geometric factors associated with aTBAD. Read More

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Infrarenal aortic balloon-expandable stent graft deployment using the sheath control technique in a patient with hemorrhagic shock secondary to an aortoenteric fistula.

J Vasc Surg Cases Innov Tech 2021 Sep 21;7(3):563-566. Epub 2021 May 21.

Division of Interventional Radiology, Mayo Clinic, Jacksonville, Fla.

A 40-year-old man presented with hemorrhagic shock owing to an aortoduodenal fistula. Angiography demonstrated vasospasm of the right common femoral artery to 2 mm. Treatment using a balloon-expandable stent graft was chosen given the smaller sheath diameter requirement when compared to self-expandable aortic stent graft. Read More

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September 2021

Right Ventricular Myocardial Adaptation Assessed by Two-Dimensional Speckle Tracking Echocardiography in Canine Models of Chronic Pulmonary Hypertension.

Front Vet Sci 2021 16;8:727155. Epub 2021 Aug 16.

Laboratory of Veterinary Internal Medicine, Faculty of Veterinary Science, School of Veterinary Medicine, Nippon Veterinary and Life Science University, Musashino, Japan.

Pulmonary hypertension (PH) is a life-threatening disease in dogs characterized by an increase in pulmonary arterial pressure (PAP) and/or pulmonary vascular resistance. Right ventricle adapts to its pressure overload through various right ventricular (RV) compensative mechanisms: adaptive and maladaptive remodeling. The former is characterized by concentric hypertrophy and increased compensatory myocardial contractility, whereas the latter is distinguished by eccentric hypertrophy associated with impaired myocardial function. Read More

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A Giant Left Circumflex Artery Aneurysm with Thrombosis Formation Presenting as a Left Atrioventricular Groove Mass.

J Cardiovasc Echogr 2021 Apr-Jun;31(2):116-118. Epub 2021 Jul 28.

Department of Radiology, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran.

A coronary artery aneurysm is defined as the dilation of a coronary artery segment that is 1.5-fold the diameter of the neighboring normal segments. A patient with a history of aortic valve replacement and coronary artery bypass graft surgery, transthoracic echocardiography revealed a large mass with an echolucent center in the left atrioventricular groove. Read More

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Ultrasound-Based Fluid-Structure Interaction Modeling of Abdominal Aortic Aneurysms Incorporating Pre-stress.

Front Physiol 2021 13;12:717593. Epub 2021 Aug 13.

Photoacoustics & Ultrasound Laboratory Eindhoven (PULS/e), Department of Biomechanical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands.

Currently, the prediction of rupture risk in abdominal aortic aneurysms (AAAs) solely relies on maximum diameter. However, wall mechanics and hemodynamics have shown to provide better risk indicators. Patient-specific fluid-structure interaction (FSI) simulations based on a non-invasive image modality are required to establish a patient-specific risk indicator. Read More

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