7,749 results match your criteria aorta primary


Paucicellular Fibroma of the Ascending Aorta.

Aorta (Stamford) 2021 Oct 12. Epub 2021 Oct 12.

Department of Cardiovascular and Thoracic Surgery, Zucker School of Medicine at Hofstra/Northwell, Manhasset, New York.

Primary tumors of the aorta are extremely rare. To the best of our knowledge, herein, we present the first case in the literature of a paucicellular fibroma originating from the aortic wall. Read More

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October 2021

Distal landing zone outcomes in thoracic endovascular aortic aneurysm repair with challenging morphology: a propensity-matched comparison of distal active fixation versus standard stent-graft.

Int Angiol 2021 Oct 12. Epub 2021 Oct 12.

Department of Vascular Surgery, Ospedale Civile di Baggiovara, Azienda Ospedaliero-Universitaria di Modena, University of Modena and Reggio Emilia, Modena, Italy.

Background: To evaluate the distal landing zone (LZ) outcomes in adverse morphology after thoracic endovascular repair (TEVAR) with distal active fixation (DAF) stent-grafts compared with standard endografts.

Methods: between 2006 and the 31st December 2020, sixty-nine DAFs (study group) and sixty-nine standard stent-grafts (control group) were enrolled in a multi-center, retrospective, case-control study. The primary outcomes were the distal endoleak and reintervention. Read More

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October 2021

Utility of Computed Tomographic Angiography for Pulmonary Hypertension Assessment in a Cohort of West Highland White Terriers With or Without Canine Idiopathic Pulmonary Fibrosis.

Front Vet Sci 2021 23;8:732133. Epub 2021 Sep 23.

Department of Clinical Sciences, Companion Animals, Faculty of Veterinary Medicine, Fundamental and Applied Research for Animals & Health (FARAH), University of Liège, Liège, Belgium.

West Highland white terriers (WHWTs) affected with canine idiopathic pulmonary fibrosis (CIPF) are at risk of developing precapillary pulmonary hypertension (PH). In humans, thoracic computed tomography angiography (CTA) is commonly used to diagnose and monitor patients with lower airway diseases. In such patients, CTA helps to identify comorbidities, such as PH, that could negatively impact prognosis. Read More

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September 2021

Pre-Loaded Fenestrated Thoracic Endografts for Distal Aortic Arch Pathologies: Multicentre Retrospective Analysis of Short and Mid Term Outcomes.

Eur J Vasc Endovasc Surg 2021 Oct 7. Epub 2021 Oct 7.

German Aortic Centre Hamburg, Department of Vascular Medicine, Hamburg, Germany.

Objective: To determine short and midterm outcomes of a pre-loaded fenestrated thoracic endograft (f-TEVAR) for exclusion of distal aortic arch pathologies.

Methods: This was a multicentre, retrospective study including consecutive patients from six experienced European vascular centres undergoing f-TEVAR for distal arch pathologies. Primary endpoints included peri-operative mortality and peri-operative stroke and/or spinal cord ischaemia rates. Read More

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October 2021

Long-term Outcomes in Ventricular Assist Device Outflow Cannula Anastomosis to the Descending Aorta.

Ann Thorac Surg 2021 Oct 7. Epub 2021 Oct 7.

Cardiovascular Surgery, Ege University School of Medicine.

Background: Left ventricular assist device (LVAD) implantation via thoracotomy with outflow cannula anastomosis to the descending aorta is an alternative implantation technique that uses a single incision and avoids anterior mediastinal planes. We evaluated long-term survival and hospital readmissions following LVAD implantation via thoracotomy with outflow cannula anastomosis to the descending aorta.

Methods: Adult patients implanted with a continuous flow centrifugal LVAD at an academic center were retrospectively analyzed. Read More

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October 2021

Prognostic Implications of Bicuspid and Tricuspid Aortic Valve Phenotype on Progression of Moderate Aortic Stenosis and Ascending Aorta Dilatation.

Am J Cardiol 2021 Oct 6. Epub 2021 Oct 6.

Department of Cardiology, National University Heart Centre Singapore, Singapore, Singapore; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. Electronic address:

Studies on the impact of aortic valve anatomy (bicuspid aortic valve [BAV] or tricuspid aortic valve [TAV]) on the progression of moderate aortic stenosis (AS) and ascending aorta (AA) dilatation and its prognostic implications are limited. From 1991 to 2016, 288 asymptomatic patients with moderate AS detected during index echocardiography with at least 1 year of echocardiographic follow-up were retrospectively studied. Baseline clinical and echocardiographic characteristics were compared between patients with BAV (n = 80) and patients with TAV (n = 208). Read More

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October 2021

Uniportal video-assisted thoracoscopic surgery for complex mediastinal mature teratoma: A case report.

World J Clin Cases 2021 Sep;9(26):7870-7875

Department of Thoracic Surgery, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, Qingdao 266035, Shandong Province, China.

Background: Mediastinal mature teratoma is the most common histological type of primary extragonadal germ cell tumor. In this report, we describe a rare case of giant mature teratoma located primarily in the anterior mediastinum and causing partial atelectasis of the upper and middle lobes of the right lung, as well as extrinsic compression of the right atrium.

Case Summary: A 31-year-old male with a giant mediastinal mature teratoma presented with progressive exertional dyspnea and chest pain for 1 mo. Read More

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September 2021

Preservation of the Aortic Root During Type A Aortic Dissection Surgery: An Effective Strategy?

Aorta (Stamford) 2021 Oct 7. Epub 2021 Oct 7.

Department of Cardiac Surgery, University Hospital of Angers, Angers, France.

Background:  Management of the aortic root during acute Type A aortic dissection (TAAD) repair remains controversial in term of long-term evolution and reoperation. The aim of this study was to assess the long-term outcomes of the aortic root after conservative management during primary surgery.

Methods:  One hundred sixty-four consecutive patients were included in this monocentric retrospective study. Read More

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October 2021

A New Method of Isolation of Mouse Renal Primary Tubular Epithelial Cells.

Authors:
H Xie Y Dai Q Zhu

Bull Exp Biol Med 2021 Sep 7;171(5):676-680. Epub 2021 Oct 7.

Department of Dermatology, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.

Kidney diseases are becoming an emerging public health problem. In order to further explore the etiology of various kidney diseases, we improved the methods of isolation of primary cultures of mouse renal tubular epithelial cells. At the first stage, the kidneys were perfused with collagenase solution. Read More

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September 2021

[A Case of Primary Neuroendocrine Carcinoma of the Retroperitoneum].

Hinyokika Kiyo 2021 Sep;67(9):423-426

The Department of Urology, Shizuoka City Shimizu Hospital.

In this case report, we describe a case of primary retroperitoneal neuroendocrine carcinoma. An 85- year-old man presented with a 3-week history of left back pain. Contrast-enhanced computed tomography showed an 8×5 cm mass to the left of the aorta and multiple hepatic metastases. Read More

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September 2021

The Pre- and Postoperative Prevalence and Risk Factors of ASA Nonresponse in Vascular Surgery.

Clin Appl Thromb Hemost 2021 Jan-Dec;27:10760296211044723

Hemophilia Centre, 14984University Hospital Frankfurt, Medical Clinic II, Institute of Transfusion Medicine and Immunhematology, Frankfurt, Germany.

Background: An antiplatelet therapy with acetylsalicylic acid (ASA) is prescribed in the prevention of cardiovascular events, but around 24% of ASA takers are resistant to the treatment.

Aim: In this prospective, observational cohort study, we aimed to identify the prevalence and risk factors of ASA nonresponse in patients who underwent vascular surgery.

Methods: The study was conducted in the University hospital in Frankfurt am Main. Read More

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October 2021

Nitrosative stress induces downregulation of ribosomal protein genes via MYCT1 in vascular smooth muscle cells.

Eur Rev Med Pharmacol Sci 2021 Sep;25(18):5653-5663

Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, China.

Objective: In our previous genomic studies in human intracranial aneurysms, we observed downregulations in the expression of a number of ribosomal protein genes and the c-Myc-related gene MYC target 1 (MYCT1). So far there is no information about the roles of MYCT1 in vascular cells. Our study aims to investigate the functional roles of MYCT1 in vascular smooth muscle cells (SMCs). Read More

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September 2021

Management and Outcomes of Proximal Aortic Graft Infection: A Systematic Review.

Heart Lung Circ 2021 Sep 30. Epub 2021 Sep 30.

Department of Cardiothoracic Surgery, Liverpool Heart and Chest, Liverpool, UK.

Objective: Proximal aortic graft infection (PAGI) is a rare but often fatal postoperative complication. Its management often relied on surgical preferences and resource availability of each centre, until the recent unifying guidelines published by the European Society for Vascular Surgery (ESVS). This paper aimed to amalgamate the published experience in managing PAGI and their outcomes. Read More

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September 2021

Percutaneous Transaxillary Access for Endovascular Aortic Procedures in the Multicenter International PAXA Registry.

J Vasc Surg 2021 Sep 29. Epub 2021 Sep 29.

Department of Cardiology, Marienkrankenhaus Hamburg, Hamburg, Germany; Department of Cardiology, Asklepios Klinik St. Georg, Hamburg, Germany.

Introduction: The aim of the study is to demonstrate the safety and effectiveness of a suture-mediated vascular closure device to perform hemostasis after an axillary artery access during endovascular procedures on the aortic valve, the aorta and its side branches.

Methods: A physician-initiated, international, multicenter, retrospective registry was designed to evaluate the success rate(VARC-2 reporting standards) of percutaneous transaxillary access closure with a suture-mediated closure device. Secondary endpoints were: minor access vascular complications, transient peripheral nerve injury, stroke, and influence on periprocedural outcomes of puncture technique. Read More

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September 2021

Outcomes following endovascular reintervention for aortic interventions.

J Vasc Surg 2021 Sep 27. Epub 2021 Sep 27.

Division of Vascular and Endovascular Surgery, Department of Surgery, Saint Louis University. Electronic address:

Objectives: Endovascular reinterventions are often done following previous open or endovascular aortic procedures. We used the Global Registry for Endovascular Aortic Treatment (GREAT) to compare outcomes between these groups and compare reintervention of any type to the group of patients who underwent primary endovascular aortic repair.

Methods: All patients enrolled in GREAT were grouped according to history of previous abdominal endovascular procedure (PEP) or open abdominal aortic procedure (OAP). Read More

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September 2021

Proximal ascending aorta size is associated with the incidence of de novo aortic insufficiency with left ventricular assist device.

Heart Vessels 2021 Sep 28. Epub 2021 Sep 28.

Department of Surgery, Section of Cardiac Surgery, The University of Chicago Medicine, 5841S Maryland Avenue, MC5040, Chicago, IL, 60637, USA.

We sought to assess the impact of the aortic root geometry on developing de novo aortic insufficiency (AI) in patients undergoing left ventricular assist device (LVAD). In total, 114 patients underwent LVAD implantation between February 2016 and January 2020 were included in this study (HeartMate3 N = 68, HeartWare N = 46). Significant aortic insufficiency was defined as mild-to-moderate or greater in echocardiography. Read More

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September 2021

Novel aspects of regulatory T cell dysfunction as a therapeutic target in giant cell arteritis.

Ann Rheum Dis 2021 Sep 28. Epub 2021 Sep 28.

Rheumatology and Immunology, Hannover Medical School, Hannover, Germany

Objectives: Giant cell arteritis (GCA) is the most common primary vasculitis, preferentially affecting the aorta and its large-calibre branches. An imbalance between proinflammatory CD4 T helper cell subsets and regulatory T cells (Tregs) is thought to be involved in the pathogenesis of GCA and Treg dysfunction has been associated with active disease. Our work aims to explore the aetiology of Treg dysfunction and the way it is affected by remission-inducing immunomodulatory regimens. Read More

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September 2021

Successful Management of Resuscitative Endovascular Balloon Occlusion of the Aorta for Hemorrhagic Shock Due to Ruptured Hepatocellular Carcinoma.

Intern Med 2021 Sep 25. Epub 2021 Sep 25.

Department of Gastroenterology, Yokohama Municipal Citizen's Hospital, Japan.

A 68-year-old man was transferred to our hospital because of sudden right costal pain with unmeasurable hypotension. Ultrasonography revealed possible hemorrhagic shock due to ruptured hepatocellular carcinoma (HCC). As the patient was not hemodynamically stable after primary treatment, resuscitative endovascular balloon occlusion of the aorta (REBOA) was performed, and hemodynamic stability was then achieved. Read More

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September 2021

Mechanobiology of the arterial tissue from the aortic root to the diaphragm.

Authors:
Hadi Taghizadeh

Med Eng Phys 2021 Oct 14;96:64-70. Epub 2021 Sep 14.

Tissue Mechanics Lab, Faculty of Biomedical Engineering, Sahand University of Technology, Tabriz, Iran. Electronic address:

Arterial tissue microstructure and its mechanical properties directly correlate with cardiovascular diseases such as atherosclerosis and aneurysm. Experienced hemodynamic loads are the primary factor of arterial tissue remodeling. By virtue of altering hemodynamic loads along the arterial tree, respective structure-function relations will be region-dependent. Read More

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October 2021

Endovascular therapies for Type B Aortic Dissection.

Cardiovasc Hematol Disord Drug Targets 2021 Sep 24. Epub 2021 Sep 24.

Department of Internal Medicine, Division of Cardiovascular Medicine, Texas Tech University, El Paso, United States. United States.

Aortic dissection is a life-threatening condition resulting from a tear in the intimal layer of the aorta, requiring emergent diagnosis and prompt multi-disciplinary management strategy for best patient outcomes. While type A dissection involving ascending aorta is best managed surgically due to high early mortality, type B aortic dissection (TBAD) involving descending aorta generally has better outcomes with conservative management and medical therapy as primary strategy is favored. However, there has been a recent paradigm shift in management of TBAD due to late aneurysmal degeneration of TBAD increasing morbidity and mortality at longer-term. Read More

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September 2021

Primary aortic intimal sarcoma masquerading as intramural hematoma.

Open Med (Wars) 2021 3;16(1):1306-1310. Epub 2021 Sep 3.

Department of Radiology, Meizhou People's Hospital, Meizhou, 514031, China.

Primary aortic intimal sarcoma is a very rare disease and most patients present with features similar to those of atherosclerotic plaque and thrombus; however, primary aortic intimal sarcoma presents with features similar to those of intramural hematoma (IMH) on CT imaging and clinical presentation had never been previously reported. Here we report a case involving a 49-year-old woman with primary aortic intimal sarcoma masquerading as IMH on radiological images and clinical presentation. We also discuss some of the diagnostic pitfalls and hope that these diagnostic pitfalls will be very useful for clinicians. Read More

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September 2021

A Novel Mechanism Underlying Inflammatory Smooth Muscle Phenotype in Abdominal Aortic Aneurysm.

Circ Res 2021 Sep 23. Epub 2021 Sep 23.

Surgery, University of Missouri-Columbia, UNITED STATES.

Abdominal aortic aneurysm (AAA) is a permanent and localized dilatation of abdominal aorta with potentially fatal consequence of aortic rupture. No effective pharmacological approach has been identified to limit AAA progression and rupture. AAA is characterized by extensive aortic wall matrix degradation that contributes to arterial wall remodeling and eventual rupture, in which smooth muscle cell (SMC) phenotypic transition and matrix metalloproteinases (MMP), especially MMP2 and MMP9, play critical roles. Read More

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September 2021

DNA Methylation Profile of the SREBF2 Gene in Human Fetal Aortas.

J Vasc Res 2021 Sep 14:1-8. Epub 2021 Sep 14.

Department of Advanced Medical and Surgical Sciences (DAMSS), University of Campania "Luigi Vanvitelli,", Naples, Italy.

Increasing evidence suggests that maternal cholesterol represents an important risk factor for atherosclerotic disease in offspring already during pregnancy, although the underlying mechanisms have not yet been elucidated. Eighteen human fetal aorta samples were collected from the spontaneously aborted fetuses of normal cholesterolemic and hypercholesterolemic mothers. Maternal total cholesterol levels were assessed during hospitalization. Read More

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September 2021

Outcomes in Patients With Obstructive Hypertrophic Cardiomyopathy and Concomitant Aortic Stenosis Undergoing Surgical Myectomy and Aortic Valve Replacement.

J Am Heart Assoc 2021 Sep 17;10(18):e018435. Epub 2021 Sep 17.

Hypertrophic Cardiomyopathy and Valve Center Heart and Vascular Institute Cleveland Clinic Cleveland OH.

Background Hypertrophic cardiomyopathy (HCM) and aortic stenosis can cause obstruction to the flow of blood out of the left ventricular outflow tract into the aorta, with obstructive HCM resulting in dynamic left ventricular outflow tract obstruction and moderate or severe aortic stenosis causing fixed obstruction caused by calcific degeneration. We sought to report the characteristics and longer-term outcomes of patients with severe obstructive HCM who also had concomitant moderate or severe aortic stenosis requiring surgical myectomy and aortic valve replacement. Methods and Results We studied 191 consecutive patients (age 67±6 years, 52% men) who underwent myectomy and aortic valve (AV) replacement (90% bioprosthesis) at our center between June 2002 and June 2018. Read More

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September 2021

Effectiveness of Short Training in Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) by Emergency Physicians: The Applied Course for Internal Aortic Clamping on Field Mission.

J Spec Oper Med 2021 ;21(3):36-40

Background: Resuscitative endovascular balloon occlusion of the aorta (REBOA) is a technique that uses internal clamping of the aorta to control abdominal, pelvic, or junctional bleeding. We created a course to train military physicians in both civilian prehospital use and battlefield use. To determine the effectiveness of this training, we conducted REBOA training for French military emergency physicians. Read More

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September 2021

[Treatment of a patient with acute thoracoabdominal aortic dissection complicated by haemothorax].

Angiol Sosud Khir 2021 ;27(3):140-145

Research Laboratory of Vascular and Hybrid Surgery of the Research Department of Vascular and Interventional Surgery, National Almazov Medical Research Centre, RF Ministry of Public Health, Saint Petersburg, Russia.

Total left-sided haemothorax is a rare and severe complication of acute DeBakey type III aortic dissection. The primary aim of treatment is immediate arrest of haemorrhage and stabilization of the haemodynamic status of the patient. Endovascular isolation of the ruptured thoracic portion of the aorta using a stent graft (TEVAR) has recently become the 'gold standard' in treatment of acute, rupture-complicated aortic dissections of this localization. Read More

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September 2021

[Prosthetic repair of the aorta with a cadaveric homograft for infection of bifurcated synthetic vascular prosthesis].

Angiol Sosud Khir 2021 ;27(3):132-139

Department of Faculty Surgery, Samara State Medical University, Samara, Russia.

Infection of arterial vascular grafts is a rare but utterly severe complication in vascular surgery. Therapeutic policy in patients with graft infection has not been standardized, to be determined individually. One of the variants of surgical treatment is considered to be repeat aortic repair using a cadaveric graft. Read More

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September 2021

Note the descending aorta: predictors of postoperative major adverse aortic event in pure acute type A intramural hematoma.

J Thorac Dis 2021 Aug;13(8):4935-4946

Department of Cardiovascular Surgery, Yonsei Cardiovascular Hospital, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.

Background: Intramural hematomas (IMHs) may originate from small intimal tears. Although most surgeries for acute type A IMH are conventionally performed solely at the proximal aorta, regardless of the primary intimal tear site, the remnant aortic remodeling stays important during the follow-up period after surgery.

Methods: Forty-seven patients with "pure" acute type A IMHs who underwent surgery from January 2008 to December 2019 were retrospectively analyzed. Read More

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Effects of menopausal hormone therapy on ambulatory blood pressure and arterial stiffness in postmenopausal Korean women with grade 1 hypertension: a randomized, placebo-controlled trial.

Clin Hypertens 2021 Sep 15;27(1):18. Epub 2021 Sep 15.

Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

Background: Estrogen therapy in early menopausal women decreases the risk of coronary heart disease and parenteral, but not oral, estrogen is reported to reduce blood pressure (BP). Progestogens are typically added to estrogens to prevent unopposed endometrial stimulation. The effects of progestogen on BP have been less well studied to date. Read More

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September 2021

Midterm Outcomes of Stented Versus Stentless Bioprosthetic Valves After Aortic Root Replacement.

Semin Thorac Cardiovasc Surg 2021 Sep 11. Epub 2021 Sep 11.

Division of Cardiac Surgery, Department of Cardiothoracic Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA; Heart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA. Electronic address:

To determine the impact of aortic root replacement (ARR) with a stentless bioprosthetic valve on midterm outcomes compared to a stented bioprosthetic valve-graft conduit. This was an observational study of aortic root operations from 2010 to 2018. All patients with a complete ARR for nonendocarditis reasons were included, while patients undergoing valve-sparing root replacements or primary aortic valve replacement or repair were excluded. Read More

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September 2021