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Association of Acute Kidney Injury with Outcomes in Patients Undergoing Transcatheter Mitral Valve Repair.

Cardiology 2021 Jun 15:1-7. Epub 2021 Jun 15.

Division of Cardiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.

Introduction: Although transcatheter mitral valve repair (TMVr) is a contrast-free procedure, prior single-center studies have demonstrated a high incidence of acute kidney injury (AKI) following TMVr. The main objective of this study was to examine risk factors for AKI, and its association with outcomes in patients undergoing TMVr.

Methods: We queried the National Readmission Database to identify TMVr procedures performed between January 2014 and December 2017. Read More

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Frequency and factors associated with post-stroke seizures in a large multicenter study in West Africa.

J Neurol Sci 2021 Jun 9;427:117535. Epub 2021 Jun 9.

Federal Medical Centre, Abeokuta, Nigeria; Center for Genomic and Precision Medicine, College of Medicine, University of Ibadan, Nigeria.

Background: Post-stroke seizures (PSS) are associated with significant morbidity and mortality across the globe. There is a paucity of data on PSS in Africa.

Purpose: To assess the frequency and factors associated with PSS by stroke types across 15 hospitals in Nigeria and Ghana. Read More

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Association of cigarette and electronic nicotine delivery systems use with internalizing and externalizing problems among US adults: Findings from wave 3 (2015-2016) of the PATH study.

PLoS One 2021 15;16(6):e0253061. Epub 2021 Jun 15.

Institute for Global Tobacco Control, Department of Health, Behavior and Society, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America.

Aims: Electronic Nicotine Delivery System (ENDS) use is increasing among US adults. While existing research has demonstrated higher cigarette smoking rates among people with mental health conditions, there is sparse information on the association between ENDS use and mental health such as internalizing and externalizing problems. The aim of this study was to evaluate associations between internalizing and externalizing problems for cigarette only, ENDS only, and dual users, as well as changes in mental health among those groups. Read More

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Factors Associated with Contraceptive Use in Sub-Saharan Africa.

J Womens Health (Larchmt) 2021 Jun 14. Epub 2021 Jun 14.

Health Social Welfare and Nutrition Division, President's Office Regional Administration and Local Government, Dar es Salaam, Tanzania.

Globally 10% of women have an unmet need for contraception, with higher rates in sub-Saharan Africa. Programs to improve family planning (FP) outcomes require data on how service characteristics (, geographic access, quality) and women's characteristics are associated with contraceptive use. We combined data from health facility assessments (2018 and 2019) and a population-based regional household survey (2018) of married and in-union women ages 15-49 in the Kigoma Region of Tanzania. Read More

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Adherence towards COVID-19 prevention measures and associated factors in Hossana town, South Ethiopia, 2021.

Int J Clin Pract 2021 Jun 15:e14530. Epub 2021 Jun 15.

Department of Public Health, College of Medicine and Health science, Wachemo University, P. O. Box. 667, Hossana, Ethiopia.

Introduction: The COVID-19 disease is a pandemic threat for humanity's healthcare system, social, economic, and psychological well-being for both developed and developing nations. In the case of developing nations such as the resource of Ethiopia, however, the key obstacle is to buy the vaccine and administer it to their people. In the study area, however, the degree of adherence to the covid-19 preventive measure was not well established. Read More

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Association of Weight Loss With Type 2 Diabetes Remission Among Adults in Medically Underserved Areas: A Retrospective Cohort Study.

Am J Health Promot 2021 Jun 15:8901171211024426. Epub 2021 Jun 15.

Center for Health System Improvement, College of Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.

Purpose: To examine the association between weight loss and type 2 diabetes remission among vulnerable populations living in medically underserved areas of the Mid-Southern United States.

Design: Quantitative, retrospective cohort study.

Setting: 114 ambulatory sites and 5 adults' hospitals in the Mid-South participating in a regional diabetes registry. Read More

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The Neighborhood Environment and Hispanic/Latino Health.

Am J Health Promot 2021 Jun 15:8901171211022677. Epub 2021 Jun 15.

UTHealth School of Public Health, Brownsville, TX, USA.

Purpose: Hispanic/Latino adults on the Texas-Mexico border have high rates of chronic disease. Neighborhoods can influence health, though there is a limited research on neighborhood environment and health in Hispanics/Latinos. The purpose of this study was to assess the relation of neighborhood environment with health variables in Hispanic/Latino adults, including physical activity [PA], depression, anxiety, and lab-assessed conditions (type 2 diabetes, metabolic syndrome, and chronic inflammation). Read More

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Impact of Cancer and Cardiovascular Disease on In-Hospital Outcomes of COVID-19 Patients: Results From the American Heart Association COVID-19 Cardiovascular Disease Registry.

Res Sq 2021 Jun 11. Epub 2021 Jun 11.

While pre-existing cardiovascular disease (CVD) appears to be associated with poor outcomes in patients with Coronavirus Disease 2019 (COVID-19), data on patients with CVD and concomitant cancer is limited. Evaluate the effect of underlying CVD and CVD risk factors with cancer history on in-hospital mortality in those with COVID-19. Data from symptomatic adults hospitalized with COVID-19 at 86 hospitals in the US enrolled in the American Heart Association’s COVID-19 CVD Registry was analyzed. Read More

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Distinct Infection Forms of SARS-CoV-2 Among People Living With HIV.

Res Sq 2021 Jun 9. Epub 2021 Jun 9.

Background: People living with HIV (PLWH) are immunodeficient, it is vague if they are more susceptible to SARS-CoV-2 infection than HIV negative individuals.

Methods: In this cross-sectional study, 857 PLWH and 1048 HIV negative individuals were enrolled from the Wuchang district in Wuhan, China. We compared the total rate of SARS-CoV-2 infection, the rate of COVID-19, asymptomatic carriers, and unapparent infectors in the two groups. Read More

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People Living with HIV Easily lose their Immune Response to SARS-CoV-2: Result From A Cohort of COVID-19 Cases in Wuhan, China.

Res Sq 2021 Jun 7. Epub 2021 Jun 7.

Background To date, whether the immune response for SARS-CoV-2 infection among people living with HIV(PLWH) is different from HIV-naïve individuals is still not clear. Methods In this cohort study, COVID-19 patients admitted to hospital in Wuhan between January 15 and April 1, 2020, were enrolled. Patients were categorized into PLWH and HIV-naïve group. Read More

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Emtricitabine triphosphate in dried blood spots predicts future viremia in persons with HIV and identifies mismatch with self-reported adherence.

AIDS 2021 Jun 14. Epub 2021 Jun 14.

Department of Biostatistics and Bioinformatics, Colorado School of Public Health, Aurora, Colorado Division of Infectious Diseases, School of Medicine, University of Colorado-AMC, Aurora, Colorado University of Colorado Hospital, Aurora, Colorado Colorado Antiviral Pharmacology Laboratory and Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado-AMC, Aurora, Colorado.

Objective: Emtricitabine triphosphate (FTC-TP) in dried blood spots (DBS), a measure of short-term ART adherence, is associated with viral suppression in persons with HIV (PWH). However, its ability to predict future viremia remains unknown.

Design: Prospective, observational cohort (up to 3 visits in 48 weeks). Read More

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Effect of multimorbidity patterns on the decline in health-related quality of life: a nationwide prospective cohort study in Japan.

BMJ Open 2021 06 14;11(6):e047812. Epub 2021 Jun 14.

Department of Healthcare Epidemiology, School of Public Health in the Graduate School of Medicine, Kyoto University, Kyoto, Japan

Objectives: Longitudinal studies, which consider multimorbidity patterns, are useful for better clarifying the effect of multimorbidity on health-related quality of life (HRQoL) and for identifying the target population with poorer clinical outcomes among patients with multimorbidity. This study aimed to examine the effects of different multimorbidity patterns on the decline in HRQoL.

Design: Nationwide prospective cohort study. Read More

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Hospitalization Risk Among Adults with Bipolar I Disorder Treated with Oral Atypical Antipsychotics: A Long-Term Data Analysis of Medicaid Claims Data.

CNS Spectr 2021 Apr;26(2):172-173

Sunovion Pharmaceuticals Inc., Marlborough, MA, USA.

Objective: To compare the risk of hospitalization for adult Medicaid beneficiaries with bipolar I disorder (BPD-I) when treated with lurasidone compared to other atypical antipsychotics (AAPs) as monotherapy.

Methods: Using IBM MarketScan Multi-State Medicaid Claims database, a retrospective cohort study was conducted on adult BPD-I patients who initiated an AAP (index date) between January 1, 2014 and June 30, 2019. Patients were required to be continuously enrolled during the 12-month pre- and 24-month post-index date. Read More

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A systematic review on the effectiveness of implementation strategies to postpone elective caesarean sections to ≥ 39 + (0-6) weeks of gestation.

Syst Rev 2021 Jun 14;10(1):176. Epub 2021 Jun 14.

Institute for Research in Operative Medicine, Witten/Herdecke University, Ostmerheimer Str. 200, Haus 38, 51109, Cologne, Germany.

Background: Caesarean sections often have no urgent indication and are electively planned. Research showed that elective caesarean section should not be performed until 39 + (0-6) weeks of gestation to ensure best neonatal and maternal health if there are no contraindications. This was recommended by various guidelines published in the last two decades. Read More

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Magnitude and determinants of neural tube defect in Africa: a systematic review and meta-analysis.

BMC Pregnancy Childbirth 2021 Jun 14;21(1):426. Epub 2021 Jun 14.

Department of Medicine, Faculty of Medicine, University of Toronto, Toronto, ON, M5S 1A8, Canada.

Background: Neural tube defects (NTDs) are a group of disorders that arise from the failure of the neural tube close between 21 and 28 days after conception. About 90% of neural tube defects and 95% of death due to these defects occurs in low-income countries. Since these NTDs cause considerable morbidity and mortality, this study aimed to determine the prevalence and associated factors of NTDs in Africa. Read More

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Early Discharge after Lobectomy for Lung Cancer does not Equate to Early Readmission.

Ann Thorac Surg 2021 Jun 11. Epub 2021 Jun 11.

Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA; VA Palo Alto Health Care System, Palo Alto, CA. Electronic address:

Background: Enhanced recovery after surgery (ERAS) pathways in several specialties reduce length of stay, but accelerated discharge after thoracic surgery is not well characterized. This study tested the hypothesis that patients discharged on post-operative day 1 (POD1) after lobectomy for lung cancer have an increased risk of readmission.

Methods: Patients who underwent a lobectomy for lung cancer between 2011-2019 in the American College of Surgeons National Surgical Quality Improvement Program database were identified. Read More

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A Group-based Modeling Approach to Identify Developmental Trajectories of Nicotine Dependence Among Lebanese Adolescents Waterpipe Smokers.

Nicotine Tob Res 2021 Jun 14. Epub 2021 Jun 14.

Department of Epidemiology, Robert Stempel College of Public Health, Florida International University, 11200 SW 8th St AHC5, 4th Floor, Miami, FL, 33199, USA.

Introduction: Adolescence represents a critical period in which nicotine dependence(ND) symptoms are developing. Little is known about waterpipe(WP) smoking and developmental trajectories of ND criteria across adolescence. Here, we aimed to identify ND trajectories from early to late adolescence in current(past 30 days) WP smokers and examine baseline correlates of each identified trajectory, using the International Classification of Diseases, 10thVersion(ICD10). Read More

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Adverse outcomes after surgeries in patients with liver cirrhosis among Korean population: A population-based study.

PLoS One 2021 14;16(6):e0253165. Epub 2021 Jun 14.

Department of Gastroenterology and Hepatology, Soonchunhyang University School of Medicine, Seoul, Korea.

Background: Patients with liver cirrhosis have an increased risk of in-hospital mortality or postoperative complication after surgery. However, large-scale studies on the prognosis of these patients after surgery are lacking. The aim of the study was to investigate the adverse outcomes of patients with liver cirrhosis after surgery over five years. Read More

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Hematological parameters of type 2 diabetic adult patients at Debre Berhan Referral Hospital, Northeast Ethiopia: A comparative cross-sectional study.

PLoS One 2021 14;16(6):e0253286. Epub 2021 Jun 14.

Faculty of Health Sciences, School of Medical Laboratory Sciences, Institute of Health, Jimma University, Jimma, Ethiopia.

Background: Diabetes is a global public health problem and associated with metabolic, cellular, and blood disturbances. Hematological changes have been reported in diabetes and play a major role in diabetes-associated complications. However, reports are contradicting and data on hematological parameters of type 2 diabetic patients in the study area are scarce. Read More

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Condom use, symptoms of suggestive sexually transmitted infections, and health care seeking among female sex workers in Bangladesh.

Int J STD AIDS 2021 Jun 14:9564624211021312. Epub 2021 Jun 14.

56291International Centre for Diarrhoeal Diseases Research, Bangladesh (icddr,b), Mohakhali, Bangladesh.

This article presents a mixed-method cross-sectional study reporting condom use, sexually transmitted infection (STI) symptoms, and care seeking of female sex workers (FSWs) in Dhaka, Bangladesh. A survey of 1228 FSWs, in-depth interviews ( = 24), and key informants' interviews ( = 26) were used for data collection. Among the 1228 FSWs included in this study, 50% of them were illiterate and 39. Read More

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Direct to Angiography vs Repeated Imaging Approaches in Transferred Patients Undergoing Endovascular Thrombectomy.

JAMA Neurol 2021 Jun 14. Epub 2021 Jun 14.

Department of Neurosurgery, The University of Texas McGovern Medical School, Houston.

Importance: A direct to angiography (DTA) treatment paradigm without repeated imaging for transferred patients with large vessel occlusion (LVO) may reduce time to endovascular thrombectomy (EVT). Whether DTA is safe and associated with better outcomes in the late (>6 hours) window is unknown. Also, DTA feasibility and effectiveness in reducing time to EVT during on-call vs regular-work hours and the association of interfacility transfer times with DTA outcomes have not been established. Read More

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Persistent COVID-19 symptoms are highly prevalent 6 months after hospitalization: results from a large prospective cohort.

Clin Microbiol Infect 2021 Apr 30. Epub 2021 Apr 30.

Université de Paris, INSERM, IAME UMR 1137, Paris, France; INSERM, Centre d'Investigation clinique-Epidémiologie Clinique 1425, Hôpital Bichat, Paris, France; Departement of Epidemiology Biostatistics and Clinical Research, AP-HP, Hôpital Bichat, Paris, France. Electronic address:

Objectives: Persistent COVID-19 symptoms have been reported up to 3 months after hospital discharge. Little is known on the frequency and the nature of persistent symptoms beyond 3 months. Here we have assessed, in the longitudinal prospective French COVID-19 cohort, symptoms that persisted 6 months after admission for COVID-19. Read More

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Pediatric Emergency Departments and Urgent Care Visits in Houston after Hurricane Harvey.

West J Emerg Med 2021 May 26;22(3):763-768. Epub 2021 May 26.

Baylor College of Medicine, Department of Pediatrics, Section of Emergency Medicine, Houston, Texas.

Introduction: Natural disasters are increasingly common and devastating. It is essential to understand children's health needs during disasters as they are a particularly vulnerable population. The objective of this study was to evaluate pediatric disease burden after Hurricane Harvey compared to the preceding month and the same period in the previous year to inform pediatric disaster preparedness. Read More

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Clinical Prediction Tool to Assess the Likelihood of a Positive SARS-Cov-2 (COVID-19) Polymerase Chain Reaction Test in Patients with Flu-like Symptoms.

West J Emerg Med 2021 Mar 24;22(3):592-598. Epub 2021 Mar 24.

Pontificia Universidad Católica de Chile, Section of Emergency Medicine, Santiago, Chile.

Introduction: The clinical presentation of coronavirus disease 2019 (COVID-19) overlaps with many other common cold and influenza viruses. Identifying patients with a higher probability of infection becomes crucial in settings with limited access to testing. We developed a prediction instrument to assess the likelihood of a positive polymerase chain reaction (PCR) test, based solely on clinical variables that can be determined within the time frame of an emergency department (ED) patient encounter. Read More

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Exposures associated with SARS-CoV-2 infection in France: A nationwide online case-control study.

Lancet Reg Health Eur 2021 Aug 7;7:100148. Epub 2021 Jun 7.

Institut Pasteur, Emerging Diseases Epidemiology Unit, Paris, France.

Background: We aimed to assess the role of different setting and activities in acquiring SARS-CoV-2 infection.

Methods: In this nationwide case-control study, cases were SARS-CoV-2 infected adults recruited between 27 October and 30 November 2020. Controls were individuals from the Ipsos market research database matched to cases by age, sex, region, population density and time period. Read More

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Retention in HIV care and its predictors among HIV-infected men who have sex with men in Plateau state, North Central Nigeria.

J Family Med Prim Care 2021 Apr 29;10(4):1596-1601. Epub 2021 Apr 29.

Department of Human Anatomy, University of Jos, Plateau State, Nigeria.

Background: Retention in HIV care is the constancy of engagement in HIV treatment, care and support services which is essential to reducing morbidity and mortality associated with the infection as well as halting the development of resistance to antiretroviral therapy (ART). In most African countries, Nigeria inclusive, men who have sex with men (MSM) are major contributors to HIV/AIDS burden. HIV-positive MSM are generally understudied and mostly underserved due to social, political and legislation factors resulting in limited characterization and documentation of the existing health disparities particularly with regards to retention in HIV care. Read More

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Risk Factors for Noninvasive Ventilation Failure in Children Post-Hematopoietic Cell Transplant.

Front Oncol 2021 27;11:653607. Epub 2021 May 27.

Department of Pediatrics, Division of Critical Care and Division of Hematology, Masonic Children's Hospital, University of Minnesota, Minneapolis, MN, United States.

Rationale: Little is known on the use of noninvasive ventilation (NIPPV) in pediatric hematopoietic cell transplant (HCT) patients.

Objective: We sought to describe the landscape of NIPPV use and to identify risk factors for failure to inform future investigation or quality improvement.

Methods: This is a multicenter, retrospective observational cohort of 153 consecutive children post-HCT requiring NIPPV from 2010-2016. Read More

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Comparison of Psychological Health Problems between Families Living with Stroke Survivors and the General Population in the Community.

Chonnam Med J 2021 May 24;57(2):118-125. Epub 2021 May 24.

Department of Preventive Medicine and Institute of Wonkwang Medical Science, Wonkwang University School of Medicine, Iksan, Korea.

This study aimed to identify and assess the differences in psychological health problems between families living with stroke survivors (FwSS) and the general population without stroke families (GwoSF). A total of 4,514 cases of FwSS were selected for analysis from the 2013 Korea Community Health Survey. In order to determine control groups in GwoSF, propensity scores were generated based on the sociodemographic characteristics of age, gender, residential region, marital status, educational level, monthly household income, and employment status. Read More

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Clinical and Laboratory Predictors of Painful Vaso-Occlusive Crisis Among Sickle Cell Disease Patients: A Single-Center Study in Saudi Arabia.

Cureus 2021 May 12;13(5):e14980. Epub 2021 May 12.

College of Medicine, King Faisal University, Al-Ahsa, SAU.

Introduction Vaso-occlusive crisis (VOC) episodes are considered to be the cause of 95% of hospitalizations for sickle cell disease (SCD) patients. The frequency of VOC is significantly associated with higher or lower lactate dehydrogenase levels, higher hemoglobin concentration, higher white blood cell, and neutrophil count, and lower platelet counts. In this study, we highlighted the association and predictors of VOC episodes in Saudi Arabia. Read More

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Determinants of Preeclampsia among Women Attending Delivery Services in Public Hospitals of Central Tigray, Northern Ethiopia: A Case-Control Study.

J Pregnancy 2021 1;2021:4654828. Epub 2021 Jun 1.

School of Nursing and Midwifery, College of Health and Medical Sciences, Haramaya University, Harar, Ethiopia.

Background: Preeclampsia occurs in up to 5% of all pregnancies, in 10% of first pregnancies, and 20-25% of women with a history of chronic hypertension.

Objective: This study aims to assess the determinants of preeclampsia among women attending delivery services in public hospitals of central Tigray, Ethiopia.

Methods: Hospital-based unmatched case-control study design was conducted. Read More

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