AIDS Rev 2021 Apr 12. Epub 2021 Apr 12.
Department of Internal Medicine and Infectious Diseases, AIDS Reference Center, Cliniques Universitaires Saint-Luc, UCLouvain, Brussels. Belgium.
Many innovations, such as long-acting agents, new delivery modalities (injectable and nanoparticles), and novel paradigms (immunotherapy or dual therapy), have been introduced to facilitate the administration of antiretroviral treatment (ART) to patients infected with HIV and improve their adherence and quality of life without altering the drugs' effectiveness. Studies have investigated the use of intermittent treatment, especially weekends-off ART in HIV-suppressed patients. In this review, we analyzed data concerning intermittent ART to help determine if this strategy is reasonable for the management of patients living with HIV. Read More