2,116 results match your criteria antioxidative status


Biological effects of stevia, sucralose and sucrose in citrus-maqui juices on overweight subjects.

Food Funct 2021 Jul 29. Epub 2021 Jul 29.

Catholic University of San Antonio (UCAM), Department of Pharmacy, Faculty of Health Sciences, Campus de los Jerónimos 30107 Guadalupe, Murcia, Spain.

Background: In the last few years there has been emerging interest in substituting added sugars from juices with other sweeteners to make them healthier. But their long-term effects have been poorly evaluated. The aim of this study is to evaluate the effect of the addition of stevia, sucralose and sucrose (control) to maqui-citrus beverages on antioxidant and inflammatory status. Read More

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Effects of pomegranate peel and olive pomace supplementation on reproduction and oxidative status of rabbit doe.

J Anim Physiol Anim Nutr (Berl) 2021 Jul 27. Epub 2021 Jul 27.

Department of Veterinary Medicine, College of Applied and Health Sciences, A'Sharqiyah University, Ibra, Oman.

The current study aimed to investigate the effects of pomegranate peel and olive pomace supplementation on the reproductive hormones, antioxidative status, reproductive capacity and maternal behaviour of rabbit does. Forty does were used for the experiments. The animals were randomly assigned to four groups of ten does. Read More

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The effects of edaravone, a free-radical scavenger in lung injury induced by valproic acid demonstrated via different biochemical parameters.

J Biochem Mol Toxicol 2021 Jul 26:e22847. Epub 2021 Jul 26.

Department of Chemistry, Faculty of Engineering, Istanbul University-Cerrahpaşa, Avcilar-Istanbul, Turkey.

In this study, we aimed to evaluate whether edaravone (EDA) has a protective role against valproic acid (VPA)-induced lung damage via its antioxidative activity. Male Sprague-Dawley rats were split into four groups. Control (n = 8) rats; rats given EDA (30 mg kg  day ; n = 10); rats given only (VPA, 500 mg kg  day ; n = 10); rats given VPA + EDA (in the same dose and time) for 7 days. Read More

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Imidacloprid induces locomotion impairment of the freshwater crayfish, Procambarus clarkii via neurotoxicity and oxidative stress in digestive system.

Aquat Toxicol 2021 Jul 16;238:105913. Epub 2021 Jul 16.

Key Laboratory of Application of Ecology and Environmental Protection in Plateau Wetland of Sichuan, Xichang University, Xichang 415000, Sichuan Province, China.

Imidacloprid (IMI) is used in integrated farming like the rice-crayfish co-culture system to prevent water weevil. However, the toxic effect of IMI on the freshwater crayfish Procambarus clarkii is unknown. In the current study, the effects of IMI on the locomotion, antioxidative status, digestion and intestinal microbiota of P. Read More

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The in vitro toxicity evaluation of halloysite nanotubes (HNTs) in human lung cells.

Toxicol Res 2021 Jul 13;37(3):301-310. Epub 2020 Oct 13.

Central Institute for Labour Protection, National Research Institute, Czerniakowska 16, 00-701 Warsaw, Poland.

Halloysite nanotubes (HNTs) have been increasingly used in many industrial and biomedical fields. Therefore, the assessment of risk and consequences of exposure to HNTs is very important to better protect human safety. This study aims to investigate the short- (24 or 72 h) and long-term (7 days) cytotoxic effects of HNTs at doses 10-200 µg/mL on human alveolar carcinoma epithelial cells (A549) and human bronchial epithelial cells (BEAS-2B). Read More

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A rice transcription factor, OsMADS57, positively regulates high salinity tolerance in transgenic Arabidopsis thaliana and Oryza sativa plants.

Physiol Plant 2021 Jul 20. Epub 2021 Jul 20.

Department of Agronomy, Zhejiang Key Lab of Crop Germplasm, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, China.

MADS-box transcription factors (TFs) play indispensable roles in various aspects of plant growth, development as well as in response to environmental stresses. Several MADS-box genes have been reported to be involved in the salt tolerance in different plant species. However, the role of the transcription factor OsMADS57 under salinity stress is still unknown. Read More

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Effects of a combination of botanical actives on skin health and antioxidant status in post-menopausal women: A randomized, double-blind, placebo-controlled clinical trial.

J Cosmet Dermatol 2021 Jul 14. Epub 2021 Jul 14.

Master of Science Program in Anti-Aging & Regenerative Medicine, College of Integrative Medicine, Dhurakij Pundit University, Bangkok, Thailand.

Background: Skin aging is one of the most concerning issues during the post-menopausal period. Despite the promising effects of hormonal therapy, there is still concerned about the long-term outcomes from the treatment. Therefore, nutraceuticals that contain estrogenic and antioxidative effects have gained a lot of attention as an alternative therapy for slowing down skin age-related changes in women after menopause. Read More

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New Markers of Platelet Activation and Reactivity and Oxidative Stress Parameters in Patients Undergoing Coronary Artery Bypass Grafting.

Oxid Med Cell Longev 2021 26;2021:8915253. Epub 2021 Jun 26.

Department for Medical Biochemistry, University of Belgrade-Faculty of Pharmacy, Belgrade, Serbia.

Objective: Recent studies have shown that the red cell distribution width- (RDW-) to-platelet (PLT) count ratio (i.e., RPR) and the mean platelet volume (MPV)/PLT ratio (i. Read More

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Research progress of melatonin (MT) in improving ovarian function: a review of the current status.

Aging (Albany NY) 2021 07 6;13(13):17930-17947. Epub 2021 Jul 6.

Reproductive Medical Center, Department of Obstetrics and Gynecology, Peking University People's Hospital, Beijing 100044, China.

Melatonin (MT) is an endogenous hormone mainly synthesized by pineal cells, which has strong endogenous effects of eliminating free radicals and resisting oxidative damages. Melatonin (MT) can not only regulate the body's seasonal and circadian rhythms; but also delay ovarian senescence, regulate ovarian biological rhythm, promote follicles formation, and improve oocyte quality and fertilization rate. This review aimd to provide evidence concerning the synthesis and distribution, ovarian function, and role of MT in development of follicles and oocytes. Read More

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Biochar and jasmonic acid application attenuates antioxidative systems and improves growth, physiology, nutrient uptake and productivity of faba bean (Vicia faba L.) irrigated with saline water.

Plant Physiol Biochem 2021 Jun 20;166:807-817. Epub 2021 Jun 20.

Botany Department, Faculty of Science, Suez Canal University, Ismailia, 41522, Egypt. Electronic address:

The effect of foliar treatment with jasmonic acid at 0.5 mM (JA) and biochar (15 ton ha) as a soil amendment for the faba bean (Vicia faba L. Sakha 4) was studied under salinity conditions. Read More

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Effects of Glucose Oxidase Supplementation on the Growth Performance, Antioxidative and Inflammatory Status, Gut Function, and Microbiota Composition of Broilers Fed Moldy Corn.

Front Physiol 2021 16;12:646393. Epub 2021 Jun 16.

College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China.

Background: Glucose oxidase is widely used as a livestock feed additive owing to its beneficial effects on growth performance and antioxidant activity. However, little is known about the effects of the enzyme on intestinal health.

Methods: To investigate the effects of glucose oxidase supplementation on the growth performance, intestinal function, and microbiota composition of broilers fed moldy corn, newly hatched Arbor Acres broilers were each randomly assigned to one of four groups, which were fed a basal diet (CON), a contaminated diet (10% moldy corn) (MC), a basal diet supplemented with 0. Read More

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Leaf as a Donor of Potentially Healthful Bioactive Compounds: Implications of Cultivar, Time of Sampling and Soil N Level.

Molecules 2021 Jun 24;26(13). Epub 2021 Jun 24.

Laboratory of Basic Sciences in Horticulture, Department of Plant Protection, Institute of Horticultural Sciences, Warsaw University of Life Sciences-SGGW, Nowoursynowska 159, 02-776 Warsaw, Poland.

The aim of this study was to assess the enzymatic and non-enzymatic antioxidant status of kiwiberry () leaf under different N regimes tested three times in field conditions during the 2015 growing season in two cultivars ('Weiki' and 'Geneva'). Leaf total antioxidant capacity using ABTS, DPPH and FRAP tests was evaluated in the years 2015 to 2017, which experienced different weather conditions. Both cultivars exhibited a significant fall in leaf L-ascorbic acid (L-AA) and reduced glutathione (GSH) as well as global content of these compounds during the growing season, while total phenolic contents slightly ('Weiki') or significantly ('Geneva') increased. Read More

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The Influence of Chicken Egg Lysozyme or Zinc-Bacitracin Antibiotic on the Growth Performance, Antibacterial Capacity, Blood Profiles, and Antioxidative Status of Rabbits: A Comparative Study.

Animals (Basel) 2021 Jun 10;11(6). Epub 2021 Jun 10.

Department of Animal Production, Faculty of Agriculture, Kafrelsheikh University, Kafr El-Sheikh 33516, Egypt.

Dietary egg lysozyme has beneficial roles in the growth performance and health conditions of animals. The study was performed using 90 multicolored rabbits in three groups (each replicate with thirty rabbits). In the control group, rabbits were fed a diet without zinc bacitracin (ZnB) or egg lysozyme, while the second and third groups were treated with ZnB and lysozyme additive at 100 mg/kg, respectively. Read More

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Effects of C60 Fullerene on Thioacetamide-Induced Rat Liver Toxicity and Gut Microbiome Changes.

Antioxidants (Basel) 2021 Jun 4;10(6). Epub 2021 Jun 4.

Faculty of Medicine, University of Belgrade, Dr. Subotića 8, 11000 Belgrade, Serbia.

Thioacetamide (TAA) is widely used to study liver toxicity accompanied by oxidative stress, inflammation, cell necrosis, fibrosis, cholestasis, and hepatocellular carcinoma. As an efficient free radical's scavenger, C60 fullerene is considered a potential liver-protective agent in chemically-induced liver injury. In the present work, we examined the hepatoprotective effects of two C60 doses dissolved in virgin olive oil against TAA-induced hepatotoxicity in rats. Read More

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Effects of Different Non-Cage Housing Systems on the Production Performance, Serum Parameters and Intestinal Morphology of Laying Hens.

Animals (Basel) 2021 Jun 4;11(6). Epub 2021 Jun 4.

Anhui Key Laboratory of Livestock and Poultry Product Safety Engineering, Institute of Animal Husbandry and Veterinary Medicine, Anhui Academy of Agriculture Science, No. 40 Nongke West Road, Hefei 230031, China.

This study investigated the effects of plastic-net housing system (NRS) and floor-litter housing system (LRS) on the production performance, serum parameters and intestinal morphology of Shendan laying hens. A total of 1200 30-week-old hens were randomly allocated to the NRS and LRS groups, each of which included five replicates with 120 chickens in each replicate. The experiment was conducted from 32 to 40 weeks of age. Read More

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Impacts of Dietary Supplementations of Orange Peel and Tomato Pomace Extracts as Natural Sources for Ascorbic Acid on Growth Performance, Carcass Characteristics, Plasma Biochemicals and Antioxidant Status of Growing Rabbits.

Animals (Basel) 2021 Jun 5;11(6). Epub 2021 Jun 5.

Animal and Poultry Production Department, Faculty of Technology and Development, Zagazig University, Zagazig 44511, Egypt.

The effect of dietary orange peel (OPE) and tomato pomace extract (TPE) supplementations on growth performance, plasma biochemicals, carcass characteristics and antioxidant status of growing male rabbits were investigated. A total of 96 rabbits (5 weeks old) were distributed into four groups. The first group received untreated pelleted diet (control). Read More

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Metal ion homeostasis with emphasis on zinc and copper: Potential crucial link to explain the non-classical antioxidative properties of vitamin D and melatonin.

Life Sci 2021 Sep 28;281:119770. Epub 2021 Jun 28.

Laboratorio de Farmacología Experimental Básica y Traslacional, Área de Farmacología, Departamento de Patología, Facultad de Ciencias Médicas, Universidad Nacional de Cuyo, Mendoza, Argentina; Instituto de Medicina y Biología Experimental de Cuyo, Consejo Nacional de Investigación Científica y Tecnológica (IMBECU-CONICET), Argentina. Electronic address:

Metal ion homeostasis is an essential physiological mechanism necessary for achieving an adequate balance of these ions' concentrations in the different cellular compartments. This fact is of great importance because both an excess and a deficiency of cellular metal ion levels are usually equally harmful due to the exacerbated increase in oxidative stress that may occur in both cases. Metal ion homeostasis ensures an equilibrium among multiple functions associated with the body's antioxidative defense network controlled by metallic micronutrients such as zinc and copper, some of the central regulators of redox processes. Read More

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September 2021

Association of vitamin A status with lung function in children and adolescents with cystic fibrosis.

Pediatr Investig 2021 Jun 18;5(2):125-129. Epub 2021 Jun 18.

Pediatric Allergy and Respiratory Unit Third Department of Pediatrics "Attikon" University Hospital National and Kapodistrian University of Athens School of Medicine Athens Greece.

Importance: Vitamin A (or retinol) has considerable antioxidative and anti-inflammatory attributes and it may have protective effects on the respiratory health of patients with cystic fibrosis (CF). This issue, however, remains controversial.

Objective: The purpose of the present study was to investigate the relationship between serum retinol levels (SRL) and force expiratory volume in 1 second (FEV1) in patients with CF. Read More

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Dietary supplementation of grape seed tannin extract stimulated testis development, changed fatty acid profiles and increased testis antioxidant capacity in pre-puberty hu lambs.

Theriogenology 2021 Jun 20;172:160-168. Epub 2021 Jun 20.

State Key Laboratory of Grassland Agro-ecosystems, Key Laboratory of Grassland Livestock Industry Innovation, Ministry of Agriculture and Rural Affairs, Engineering Research Center of Grassland Industry, Ministry of Education, College of Pastoral Agriculture Science and Technology, Lanzhou University, Lanzhou, 730020, China; Gansu Runmu Biological Engineering Co., Ltd., Yongchang, 737200, China; Biotechnology Engineering Laboratory of Gansu Meat Sheep Breeding, Minqin, 733300, China. Electronic address:

Grape seed tannin extract (GPE) from wine grape pomace has many effective anti-oxidative effects and is used as a promising natural feed additive in the animal feed industry. This study investigated the effect of GPE as a source of tannin on the antioxidant capacity and testis development in Hu lambs. Twenty-seven 3-month-old ram lambs were randomly assigned to three groups. Read More

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Smoking increases oral mucosa susceptibility to Candida albicans infection via the Nrf2 pathway: In vitro and animal studies.

J Cell Mol Med 2021 Jun 21. Epub 2021 Jun 21.

Nanjing Stomatological Hospital & State Key Laboratory of Analytical Chemistry for Life Science, Medical School, Nanjing University, Nanjing, China.

Smoking and Candida albicans (C. albicans) infection are risk factors for many oral diseases. Several studies have reported a close relationship between smoking and the occurrence of C. Read More

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Pomegranate peel as a phytogenic in broiler chickens: Influence upon antioxidant, lipogenesis and hypotensive response.

Vet Med Sci 2021 Jun 15. Epub 2021 Jun 15.

Faculty of Agriculture, Department of Animal Science, Shahrekord University, Shahrekord, Iran.

The aim of this study was to evaluate antioxidant, antihyperlipidemic and hypotensive properties of pomegranate peel (PP) on antioxidant status, fat deposition, lipid peroxidation and pulmonary hypertensive response in broiler chickens. A total of 375 one-day-old male broilers (Cobb 500) were randomly assigned to five treatments included dietary PP levels of 0, 2.5, 5. Read More

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Ecophysiological, anatomical, and apigenin changes due to uptake and accumulation of cadmium in Matricaria chamomilla L. flowers in hydroponics.

Environ Sci Pollut Res Int 2021 Jun 15. Epub 2021 Jun 15.

Department of Plant Biology, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran.

Cadmium (Cd) is one of the most important heavy metals in the environment which has several effects on the morphology, physiology, and anatomy of plants. It is a mobile heavy metal that can be transferred easily into plants, thus entering into the human food chain. Chamomile (Matricaria chamomilla L. Read More

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The potential neuroprotective effect of allicin and melatonin in acrylamide-induced brain damage in rats.

Environ Sci Pollut Res Int 2021 Jun 12. Epub 2021 Jun 12.

Biochemistry Department, Faculty of Veterinary Medicine, Alexandria University, Alexandria, Egypt.

Acrylamide (ACR) is an unsaturated monomer that served various fields; however, it is a potent neurotoxin. The target of the present study is to explore the neuroprotective efficacy of allicin and melatonin on ACR-induced neurotoxicity. Thirty-six male adult rats were non-selectively separated into six groups: placebo, allicin (20 mg/kg b. Read More

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Long term salinity disrupts the hepatic function, intestinal health, and gills antioxidative status in Nile tilapia stressed with hypoxia.

Ecotoxicol Environ Saf 2021 Sep 10;220:112412. Epub 2021 Jun 10.

The Center for Applied Research on the Environment and Sustainability, The American University in Cairo, 11835 Cairo, Egypt; Department of Engineering Hydrology, RWTH Aachen University, Aachen, Germany. Electronic address:

In aquaculture, fish are stressed with several factors involved in impacting the growth rate and health status. Although Nile tilapia can resist brackish water conditions, hypoxia status may impair the health condition of fish. Nile tilapia were exposed to salinity water at 0, 10, and 20‰ for four weeks then the growth behavior was checked. Read More

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September 2021

Evaluation of serum antioxidative status, immune status and intestinal condition of Linwu duck challenged by lipopolysaccharide with various dosages and replications.

Poult Sci 2021 Jul 20;100(7):101199. Epub 2021 Apr 20.

Hunan Institute of Animal and Veterinary Science, Changsha 410131, China. Electronic address:

The present study investigated the dosage and replication effects of lipopolysaccharide challenges on the serum oxidative and immune status, and the intestinal morphology and permeability of Linwu ducks at the growing stage. A total of 500 54-day-old Linwu ducks were randomly assigned into 10 treatments, which included a factorial arrangement of 2 levels of LPS challenge replications (1 and 2 times) × 5 levels of lipopolysaccharide challenging dosages (0, 0.1, 0. Read More

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An Adsorptive and Antioxidant Vaginal Gel Clears High-Risk HPV- and p16/Ki-67-Associated Abnormal Cytological Cervical Findings: A Subgroup Analysis of a Prospective Randomized Controlled Trial on CIN2 and p16 Positive CIN1.

Front Med (Lausanne) 2021 25;8:645559. Epub 2021 May 25.

Department of Obstetrics and Gynaecology, University Hospital of Geneva, Geneva, Switzerland.

To analyze the course of p16/Ki-67-positive abnormal cytological cervical findings and high risk (hr)-HPV- and p16/Ki-67-clearances in women treated with a vaginal gel. 172 women with a histological diagnosis of CIN2 or p16-positive CIN1 lesions were selected based on a positive cytological p16/Ki-67 test. For 3 months, 75 patients in the active arm (AA) daily administered 5 ml of a vaginal gel. Read More

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Resveratrol and its derivative pterostilbene ameliorate intestine injury in intrauterine growth-retarded weanling piglets by modulating redox status and gut microbiota.

J Anim Sci Biotechnol 2021 Jun 10;12(1):70. Epub 2021 Jun 10.

College of Animal Science and Technology, Nanjing Agricultural University, No.1 Weigang Street, Nanjing, Jiangsu, 210095, People's Republic of China.

Background: Intestinal disorder is an important factor contributing to growth lag and high rates of morbidity and mortality of piglets with intrauterine growth retardation (IUGR). Resveratrol (RSV) and its derivative pterostilbene (PT) are natural stilbenes possessing various bioactivities, such as antioxidative and anti-inflammatory effects. This study compared the protective potential of RSV and PT on the intestinal redox status and gut microbiota in weanling piglets with IUGR. Read More

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Dichlorophene activates aryl hydrocarbon receptor (AhR) and indoleamine 2, 3-dioxygenase 1 (IDO1) to mediate splenotoxicity in rat.

Drug Chem Toxicol 2021 Jun 9:1-8. Epub 2021 Jun 9.

Department of Physiology, Serampore College, Hooghly, India.

Dichlorophene (DCP) is a halogenated phenolic compound, widely used as fungicide, bactericide and antiprotozoan and also exhibit therapeutic application in several pathological conditions. Taking account of broad use of DCP, its possible effect on spleen (an important immune organ) was investigated in this study. Male albino rats were treated with graded doses of DCP (10%, 20% and 30% of LD50) and spleen and blood were obtained at 24, 48 and 72 hours post treatment. Read More

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Interactive effects of vitamins A and K on laying performance, egg quality, tibia attributes and antioxidative status of aged Roman Pink laying hens.

Animal 2021 Jun 3;15(6):100242. Epub 2021 Jun 3.

Hubei Key Laboratory of Animal Nutrition and Feed Science, Wuhan Polytechnic University, Wuhan 430023, China. Electronic address:

Extending laying cycle is a tendency in hen breeding, but egg quality declines as laying hens age. The present study was conducted to investigate the interactive effects of vitamins A and K on laying performance, egg and tibia quality, and antioxidative status of aged Roman Pink laying hens. In a 3 × 3 factorial arrangement, 1 080 87-week-old laying hens were allocated to nine groups with eight replicates in each group. Read More

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Relation of Serum Copper Status to Survival in COVID-19.

Nutrients 2021 May 31;13(6). Epub 2021 May 31.

Institute for Experimental Endocrinology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, D-10115 Berlin, Germany.

The trace element copper (Cu) is part of our nutrition and essentially needed for several cuproenzymes that control redox status and support the immune system. In blood, the ferroxidase ceruloplasmin (CP) accounts for the majority of circulating Cu and serves as transport protein. Both Cu and CP behave as positive, whereas serum selenium (Se) and its transporter selenoprotein P (SELENOP) behave as negative acute phase reactants. Read More

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