10,294 results match your criteria antioxidative activity


Effects of dietary resveratrol supplementation on the chemical composition, oxidative stability and meat quality of ducks (Anas platyrhynchos).

Food Chem 2021 Jun 1;363:130263. Epub 2021 Jun 1.

Laboratory of Molecular Nutrition, Institute of Animal Nutrition, Northeast Agricultural University, Harbin 150030, PR China. Electronic address:

The effects of dietary resveratrol (0, 300, 400 and 500 mg/kg) on the chemical composition, antioxidative capacity, meat quality and volatile compound concentrations of duck meat were investigated. The results showed that dietary resveratrol had no significant effects on the chemical composition. Dietary resveratrol supplementation increased superoxide dismutase, glutathione peroxidase, catalase activity, pH, pH and color, and reduced the malondialdehyde, and carbonyl contents and shear force, thereby improving water mobility and distribution (T, T, T), drip loss, cooking loss and volatile compounds concentration of duck meat. Read More

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Silicon elevated cadmium tolerance in wheat (Triticum aestivum L.) by endorsing nutrients uptake and antioxidative defense mechanisms in the leaves.

Plant Physiol Biochem 2021 May 31;166:148-159. Epub 2021 May 31.

Department of Botany and Microbiology, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.

Numerous abiotic stressors including heavy metal stresses, specifically cadmium (Cd) stress in agricultural bio-system hinder the plant adequate growth. The present study was aimed to reveal the protective role of silicon (Si) application with two levels and to recognize the optimum level of Si for wheat plants grown hydroponically under three different levels of Cd toxicities. In methodology, we used nine treatments with three levels of Si (0, 1, and 3 mmol L; NaSiO) against three levels of Cd (0, 50, 200 μmol L; CdCl) with three biological replicates. Read More

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Short term intensified training temporarily impairs mitochondrial respiratory capacity in elite endurance athletes.

J Appl Physiol (1985) 2021 06 10. Epub 2021 Jun 10.

Department of Physiology, Nutrition and Biomechanics, Åstrand Laboratory, Swedish School of Sport and Health Sciences, Stockholm, Sweden.

Aim: The maintenance of healthy and functional mitochondria is the result of a complex mitochondrial turnover and herein quality-control program which includes both mitochondrial biogenesis and autophagy of mitochondria. The aim of this study was to examine the effect of an intensified training load on skeletal muscle mitochondrial quality control in relation to changes in mitochondrial oxidative capacity, maximal oxygen consumption and performance in highly trained endurance athletes.

Methods: 27 elite endurance athletes performed high intensity interval exercise followed by moderate intensity continuous exercise 3 days per week for 4 weeks in addition to their usual volume of training. Read More

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Preparation of a water soluble aminated β-1,3-D-glucan for gene carrier: The in vitro study of the anti-inflammatory activity and transfection efficiency.

J Biomed Mater Res A 2021 Jun 10. Epub 2021 Jun 10.

School of Biotechnology and Health Sciences, Wuyi University, Jiangmen, China.

β-1,3-D-glucan has been reported to have a series of bioactivities including antitumor, antimicrobial, anti-inflammatory and antioxidative effects; however, its insolubility in neutral aqueous solution significantly restricts the potential application in biological and medicine fields. Herein, a water-soluble aminated β-1,3-D-glucan (AG) was synthesized and the anti-inflammatory effect, cytotoxicity and plasmid DNA (pDNA) binding capacity of AG, serum stability, the particle sizes and zeta potentials of AG/pDNA nanocomposites, and the transfection efficiency and mechanism of action were studied. AG shows no obvious cytotoxicity within the range of working concentration (1-64 μg/ml) and it exerts potent anti-inflammatory effect independent on Dectin-1 and TLR2. Read More

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Resveratrol and its derivative pterostilbene ameliorate intestine injury in intrauterine growth-retarded weanling piglets by modulating redox status and gut microbiota.

J Anim Sci Biotechnol 2021 Jun 10;12(1):70. Epub 2021 Jun 10.

College of Animal Science and Technology, Nanjing Agricultural University, No.1 Weigang Street, Nanjing, Jiangsu, 210095, People's Republic of China.

Background: Intestinal disorder is an important factor contributing to growth lag and high rates of morbidity and mortality of piglets with intrauterine growth retardation (IUGR). Resveratrol (RSV) and its derivative pterostilbene (PT) are natural stilbenes possessing various bioactivities, such as antioxidative and anti-inflammatory effects. This study compared the protective potential of RSV and PT on the intestinal redox status and gut microbiota in weanling piglets with IUGR. Read More

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Inclusion of microbe-derived antioxidant during pregnancy and lactation attenuates high-fat diet-induced hepatic oxidative stress, lipid disorders, and NLRP3 inflammasome in mother rats and offspring.

Food Nutr Res 2019 23;63. Epub 2019 Aug 23.

Shanghai Key Laboratory of Veterinary Biotechnology, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, China.

Objective: This study aimed to evaluate the effects of microbe-derived antioxidant (MA) on high-fat diet (HFD)-induced hepatic lipid disorders in mother rats and offspring.

Methods: A total of 36 female rats were randomly divided into three groups at the beginning of pregnancy: the control group (CG), HFD, and HFD with 2% MA. Mother rats were slaughtered at the first and 10th day of lactation (L1 and L10) and offspring were slaughtered at L10. Read More

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Antioxidative and anti-inflammatory activity of psiguadial B and its halogenated analogues as potential neuroprotective agents.

Bioorg Chem 2021 May 26;113:105027. Epub 2021 May 26.

New Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu 41061, Republic of Korea. Electronic address:

Psiguadial B (8), and its fluoro- (8a), chloro- (8b), and bromo- (8c) derivatives were synthesized using a sodium acetate-catalyzed single step coupling of three components: β-caryophyllene (5), diformylphloroglucinol (11), and benzaldehyde (12). These compounds efficiently and dose-dependently decreased HO-induced cell death, a quantitative marker of cell death, in primary cultures of mouse cortical neurons. Psiguadial B also decreased neuronal death and accumulation of ROS induced by FeCl in cortical cultures. Read More

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Combined Effect of the Essential Oil and Collagen Film on the Quality of Pacific Mackerel () Fillet During Cold Storage.

Foodborne Pathog Dis 2021 Jun 4. Epub 2021 Jun 4.

Department of Food Science and Pharmaceutics, Zhejiang Ocean University, Zhoushan, China.

Essential oils (EOs) and collagen have received recent attention in the seafood industry due to their abilities of antibacterial and seafood preservation individually. However, to the authors' best knowledge, very few publications address the issue of the combined effect of EOs and collagen on seafood preservation. Pacific mackerel is one of the most economically valuable fish species in China and easy to deteriorate during storage. Read More

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Fullerol-hydrogel microfluidic spheres for redox regulation of stem cell fate and refractory bone healing.

Bioact Mater 2021 Dec 24;6(12):4801-4815. Epub 2021 May 24.

Department of Orthopedics, Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Shanghai Institute of Traumatology and Orthopaedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197 Ruijin 2nd Road, Shanghai, 200025, PR China.

The balance of redox homeostasis is key to stem cell maintenance and differentiation. However, this balance is disrupted by the overproduced reactive oxygen species (ROS) in pathological conditions, which seriously impair the therapeutic efficacy of stem cells. In the present study, highly dispersed fullerol nanocrystals with enhanced bioreactivity were incorporated into hydrogel microspheres using one-step innovative microfluidic technology to construct fullerol-hydrogel microfluidic spheres (FMSs) for regulating the redox homeostasis of stem cells and promoting refractory bone healing. Read More

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December 2021

Utilization of Maillard reaction in moist-dry-heating system to enhance physicochemical and antioxidative properties of dried whole longan fruit.

Heliyon 2021 May 22;7(5):e07094. Epub 2021 May 22.

Division of Product Development Technology, Faculty of Agro-Industry, Chiang Mai University, Chiang Mai 50100, Thailand.

This research aimed to enhance the physicochemical and antioxidant properties of dried whole longan fruit using Maillard reaction or non-enzymatic glycosylation (glycation) in a moist-dry-heating system at 60 °C with approximately 75% relative humidity for 5-50 days. During Maillard reaction, the browning index (BI) of the fruits increased significantly while lightless, redness and yellowness decreased. Interestingly, the rare sugars especially D-psicose and D-allose gradually increased by 2-3 folds when compared to the initial Maillard reaction. Read More

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Phenol-like group functionalized graphene quantum dots structurally mimicking natural antioxidants for highly efficient acute kidney injury treatment.

Chem Sci 2020 Aug 5;11(47):12721-12730. Epub 2020 Aug 5.

State Key Laboratory of Rare Earth Resources Utilization, Laboratory of Chemical Biology, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences Changchun 130022 P. R. China

Acute kidney injury (AKI) is a syndrome characterized by rapid loss of renal excretory function with high in-hospital mortality. The excess generation of reactive oxygen species (ROS) in the kidneys during AKI has been considered a major cause of renal failure. Currently available antioxidants for AKI treatment often lack the required antioxidative efficacy or renal accumulation rate. Read More

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Enhanced Reproductive Thermotolerance of the Tomato Mutant Is Associated With Increased Accumulation of Flavonols in Pollen.

Front Plant Sci 2021 19;12:672368. Epub 2021 May 19.

Institute of Plant Sciences, Agricultural Research Organization - Volcani Center, Rishon LeZion, Israel.

Climate change has created an environment where heat stress conditions are becoming more frequent as temperatures continue to raise in crop production areas around the world. This situation leads to decreased crop production due to plant sensitivity to heat stress. Reproductive success is critically dependent on plants' ability to produce functional pollen grains, which are the most thermo-sensitive tissue. Read More

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Protects Against Oxidative Cardiotoxicity by Suppressing Lipid Dysmetabolism and Modulating Cardiometabolic Activities Linked to Cardiac Dysfunctions.

Front Pharmacol 2021 20;12:610835. Epub 2021 May 20.

Department of Biochemistry, School of Life Sciences, University of KwaZulu-Natal, Durban, South Africa.

Cardiotoxicity leading to cardiovascular dysfunction and ultimately cardiac failure remains a major global health issue irrespective of race, age and country. Several factors including lipotoxicity, oxidative imbalance, exacerbated angiotensin-converting enzyme (ACE) activity and altered bioenergetics have been implicated in the pathophysiology of cardiovascular diseases. (E. Read More

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The Whitening Properties of the Mixture Composed of Pomegranate, Osmanthus and Olive and the Protective Effects Against Ultraviolet Deleterious Effects.

Clin Cosmet Investig Dermatol 2021 27;14:561-573. Epub 2021 May 27.

Infinitus Company Ltd, Guangzhou, People's Republic of China.

Background: Ultraviolet (UV) rays are the major environmental factor that damage skin physiology causing deleterious effects such as oxidation, photoaging and pigmentation. There has been considerable interest in using botanicals to prevent skin damages caused by UV irradiation.

Aim: In this study, three plant extracts were tested either individually or combined together (mixture) as well as their corresponding main active compound: pomegranate/punicalagin, osmanthus/verbascoside and olive/hydroxytyrosol. Read More

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Methyl jasmonate ameliorates lead toxicity in by modulating chlorophyll metabolism, antioxidative capacity and metal translocation.

Physiol Mol Biol Plants 2021 May 20;27(5):1089-1104. Epub 2021 Apr 20.

Department of Agronomy, Islamic Azad University of Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran.

Lead (Pb) not only negatively alters plant growth and yield but may also have potentially toxic risks to human health. Nevertheless, the interaction between rice ( L.) plants and the molecular cell dynamics induced by lead-methyl jasmonate (MJ) remains unknown. Read More

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Interactive effects of vitamins A and K on laying performance, egg quality, tibia attributes and antioxidative status of aged Roman Pink laying hens.

Animal 2021 Jun 3;15(6):100242. Epub 2021 Jun 3.

Hubei Key Laboratory of Animal Nutrition and Feed Science, Wuhan Polytechnic University, Wuhan 430023, China. Electronic address:

Extending laying cycle is a tendency in hen breeding, but egg quality declines as laying hens age. The present study was conducted to investigate the interactive effects of vitamins A and K on laying performance, egg and tibia quality, and antioxidative status of aged Roman Pink laying hens. In a 3 × 3 factorial arrangement, 1 080 87-week-old laying hens were allocated to nine groups with eight replicates in each group. Read More

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Injectable self-healing bioactive antioxidative one-component poly(salicylic acid) hydrogel with strong ultraviolet-shielding for preventing skin light injury.

Mater Sci Eng C Mater Biol Appl 2021 Jul 21;126:112107. Epub 2021 Apr 21.

State key laboratory for manufacturing, systems engineering, Xi'an Jiaotong University, Xi'an 710000, China; Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an 710000, China; National and Local Joint Engineering Research Center of Biodiagnosis and Biotherapy, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710000, China; Instrument Analysis Center, Xi'an Jiaotong University, Xi'an 710054, China. Electronic address:

The design and development of one-component temperature-sensitive bioactive hydrogel with multifunctional properties for protecting skin against light injury remain a challenge. Herein, we report a bioactive multifunctional poly(salicylic acid)-F127-poly(salicylic acid) copolymer hydrogel (FPSa) with one-component for potential skin protection applications. The FPSa hydrogel possesses the thermosensitivity (23 °C), injectability, self-healing ability, ultraviolet shielding (shielding the wavelength between 280 and 370 nm), and antioxidation activity (above 70%), and also showed the good cytocompatibility (cell survival rate >90% and hemolysis rate less than 5%) and biodegradability (90% weight loss at 3 days). Read More

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Apolipoprotein E genotype, lifestyle and coronary artery disease: Gene-environment interaction analyses in the UK Biobank population.

Atherosclerosis 2021 May 27;328:33-37. Epub 2021 May 27.

Department of Internal Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands. Electronic address:

Background And Aims: The APOE ε4 genotype has a higher risk for developing coronary artery disease (CAD), but there is preliminary evidence that antioxidative lifestyle factors interact with APOE genotype on CAD risk. Here, we assessed the effect modification of physical activity, oily fish and polyunsaturated fatty acid (PUFA) intake with APOE genotype on risk of incident CAD.

Methods: The present study comprised 345,659 white European participants from UK Biobank (mean age: 56. Read More

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Combination of and Galacto-Oligosaccharide Protects the Skin from Photoaging.

J Med Food 2021 Jun 2. Epub 2021 Jun 2.

Division of Food and Nutrition and Human Ecology Research Institute, Chonnam National University, Gwangju, Korea.

Overexposure to ultraviolet B (UVB) irradiation induces photoaging that is characterized by the formation of wrinkles and loss of skin elasticity. To understand the mechanism of action of probiotics and prebiotics in skin protection against photoaging, we investigated the effects of dietary supplementation with the probiotic, , and prebiotic, galacto-oligosaccharide, on UVB-induced photoaging in hairless mice. We measured short chain fatty acid (SCFA) levels, antioxidant enzyme activity, and inflammatory signaling protein levels to elucidate the possible mechanisms underlying the effects of the dietary supplements and galacto-oligosaccharide. Read More

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Distribution of Polyphenolic and Isoprenoid Compounds and Biological Activity Differences between in the Fruit Skin + Pulp, Seeds, and Leaves of New Biotypes of Thunb.

Antioxidants (Basel) 2021 May 26;10(6). Epub 2021 May 26.

Department of Fermentation and Cereals Technology, Wrocław University of Environmental and Life Science, Chełmońskiego 37, 51-630 Wroclaw, Poland.

The purpose of this study was to determine the distribution of polyphenolic and isoprenoid compounds and organic acids in the fruit skin + pulp, seeds, and leaves of six new biotypes of Thunb., as well as their in vitro biological potency. The polyphenols and isoprenoids were determined with UPLC-PDA-MS/MS (ultra-performance liquid chromatography coupled to photodiode array detection and electrospray ionization tandem mass spectrometry) and RRLC-MS/MS (rapid resolution liquid chromatography/tandem mass spectrometry) methods, the organic acid with HPLC-RID (high-performance liquid chromatography coupled to a Refractive Index Detector), and the antioxidant capacity using ABTS and FRAP assays. Read More

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Aqueous Extract: Role of Condensed Tannins in Anti-Aflatoxin B1 Activity in .

Toxins (Basel) 2021 May 29;13(6). Epub 2021 May 29.

Toxalim (Research Center in Food Toxicology), Université de Toulouse, INRAE, ENVT, EI-Purpan, 313000 Toulouse, France.

Aflatoxin B1 (AFB1) is a potent carcinogenic mycotoxin that contaminates numerous crops pre- and post-harvest. To protect foods and feeds from such toxins without resorting to pesticides, the use of plant extracts has been increasingly studied. The most interesting candidate plants are those with strong antioxidative activity because oxidation reactions may interfere with AFB1 production. Read More

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Importance of Genetic Polymorphisms in and Genes in Metals Homeostasis and Their Relationship with the Risk of Acute Pancreatitis Occurrence in Smokers-Preliminary Findings.

Int J Mol Sci 2021 May 27;22(11). Epub 2021 May 27.

Department of Biomedical and Environmental Analyses, Faculty of Pharmacy, Wroclaw Medical University, 50-556 Wroclaw, Poland.

This study was aimed at evaluating the changes in metallothionein (MT) concentration in the blood of patients with acute pancreatitis (AP) and healthy subjects, taking into account the extracellular (plasma) and intracellular (erythrocyte lysate) compartments. The impact of single-nucleotide polymorphisms (SNPs) in the (rs11640851), (rs964372) and (rs10636) genes on MT concentration and their association with the concentration of metals (Cu, Zn, Cd) and ceruloplasmin as Cu-related proteins were analyzed. The concentration of a high-sensitivity C-reactive protein (hs-CRP) and IL-6 as markers of inflammation, and malonyldialdehyde (MDA), superoxide dismutase (SODs) activity and the value of total antioxidant capacity (TAC) as parameters describing the pro/antioxidative balance were also assessed. Read More

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EMS Derived Wheat Mutant BIG8-1 ( L.)-A New Drought Tolerant Mutant Wheat Line.

Int J Mol Sci 2021 May 18;22(10). Epub 2021 May 18.

Department of Genetics, University of Stellenbosch, Stellenbosch 7601, South Africa.

Drought response in wheat is considered a highly complex process, since it is a multigenic trait; nevertheless, breeding programs are continuously searching for new wheat varieties with characteristics for drought tolerance. In a previous study, we demonstrated the effectiveness of a mutant known as RYNO3936 that could survive 14 days without water. In this study, we reveal another mutant known as BIG8-1 that can endure severe water deficit stress (21 days without water) with superior drought response characteristics. Read More

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The Impacts of Woolly Cupgrass on the Antioxidative System and Growth of a Maize Hybrid.

Plants (Basel) 2021 May 14;10(5). Epub 2021 May 14.

Institute of Food Science, University of Debrecen, 138 Böszörményi St., 4032 Debrecen, Hungary.

Woolly cupgrass ( (Thunb.) Kunth) is a new invasive weed in Hungary. This study was conducted to elucidate the effects of this weed on the biochemistry and growth of maize ( L. Read More

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Exogenous Potassium (K) Positively Regulates Na/H Antiport System, Carbohydrate Metabolism, and Ascorbate-Glutathione Cycle in HS-Dependent Manner in NaCl-Stressed Tomato Seedling Roots.

Plants (Basel) 2021 May 10;10(5). Epub 2021 May 10.

Department of Plant Physiology, Institute of Biology, Warsaw University of Life Sciences SGGW, 159 Nowoursynowska 159, 02-776 Warsaw, Poland.

Potassium (K) is one of the vital macronutrients required by plants for proper growth and blossoming harvest. In addition, K also plays a decisive role in promoting tolerance to various stresses. Under stressful conditions, plants deploy their defense system through various signaling molecules, including hydrogen sulfide (HS). Read More

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Therapeutic Effects of with High Antioxidative Activity Against UV-Induced Photoaging of NHDF Cells and Nude Mice.

Antioxidants (Basel) 2021 May 17;10(5). Epub 2021 May 17.

Department of Biomaterials Science (BK21 FOUR Program), College of Natural Resources and Life Science/Longevity & Wellbeing Research Center, Pusan National University, Miryang 50463, Korea.

To investigate the therapeutic effects of methanol extracts of Roxb. (MED) against UV-induced photoaging, we assessed for alterations in the antioxidant activity, anti-apoptotic effects, ECM modulation, skin appearances, and anti-inflammatory response in normal human dermal fibroblast (NHDF) cells and nude mice orally treated with MED. High levels of tannin content and high free radical scavenging activity to DPPH were determined in MED, while seven active components, namely, gallic acid, bergenin, ellagic acid, ε-viniferin, asiatic acid, oleanolic acid, and 2α-hydroxyursolic acid, were identified using LC-MS analyses. Read More

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Research Development on Anti-Microbial and Antioxidant Properties of Camel Milk and Its Role as an Anti-Cancer and Anti-Hepatitis Agent.

Antioxidants (Basel) 2021 May 17;10(5). Epub 2021 May 17.

State Key Laboratory of Animal Nutrition, Beijing Engineering Technology Research Center of Raw Milk Quality and Safety Control, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.

Camel milk is a rich source of vitamin C, lactic acid bacteria (LAB), beta-caseins and milk whey proteins, including lactoferrin, lysozyme, lactoperoxidase, alpha-lactalbumin and immunoglobulin. The lactoferrin plays a key role in several physiological functions, such as conferring antioxidant, anti-microbial and anti-inflammatory functions in cells. Similarly, the camel milk alpha-lactalbumin has shown greater antioxidative activity because of its higher antioxidant amino acid residues. Read More

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Production and Characterization of Medium-Sized and Short Antioxidant Peptides from Soy Flour-Simulated Gastrointestinal Hydrolysate.

Antioxidants (Basel) 2021 May 6;10(5). Epub 2021 May 6.

Department of Chemistry, Università di Roma "La Sapienza", Piazzale Aldo Moro 5, 00185 Rome, Italy.

Soybeans () are an excellent source of dietary proteins and peptides with potential biological activities, such as antihypertensive, anti-cholesterol, and antioxidant activity; moreover, they could prevent cancer. Also, soy contains all the essential amino acids for nutrition; therefore, it represents an alternative to animal proteins. The goal of this paper was the comprehensive characterization of medium-sized and short peptides (two to four amino acids) obtained from simulated gastrointestinal digestion. Read More

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Potential Health Benefits Associated with Lunasin Concentration in Dietary Supplements and Lunasin-Enriched Soy Extract.

Nutrients 2021 May 12;13(5). Epub 2021 May 12.

Center for Crops Utilization Research, Iowa State University, Ames, IA 50011, USA.

Lunasin has demonstrated antioxidative, anti-inflammatory, and chemopreventive properties. The objectives were to evaluate the concentration of lunasin in different lunasin-based commercial dietary supplements, to produce a lunasin-enriched soy extract (LESE) using a two-step pilot-plant-based ultrafiltration process, and to evaluate their biological potential in vitro. LESE was produced using 30 and 1 kDa membranes in a custom-made ultrafiltration skid. Read More

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Effect of Bee Pollen Addition on the Polyphenol Content, Antioxidant Activity, and Quality Parameters of Honey.

Antioxidants (Basel) 2021 May 20;10(5). Epub 2021 May 20.

Department of Food Analysis and Evaluation of Food Quality, Faculty of Food Technology, University of Agriculture in Krakow, Balicka 122 Str., 30-149 Krakow, Poland.

Bee pollen is regarded as a valuable source of bioactive substances. Honey enrichment with bee pollen seems to be the most popular way to introduce this bee product into a human diet. The aim of this study was to determine the influence of the addition of bee pollen to honey on the content of selected biologically active pollen components, antioxidant activity, and quality parameters, as well as sensory properties. Read More

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