41,279 results match your criteria antioxidant capacity


Daily apple consumption reduces plasma and peripheral blood mononuclear cell-secreted inflammatory biomarkers in adults with overweight and obesity: a 6-week randomized, controlled, parallel-arm trial.

Am J Clin Nutr 2021 May 8. Epub 2021 May 8.

Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada.

Background: Obesity-associated low-grade inflammation contributes to the development of cardiovascular disease (CVD). Apples are rich in anti-inflammatory bioactives including polyphenols and fiber.

Objectives: We aimed to determine the effects of regular apple consumption on fasting plasma biomarkers of inflammation (primary outcome), endotoxemia, carbohydrate and lipid metabolism (glucose, insulin, triacylglycerol; secondary outcomes), and peripheral blood mononuclear cell (PBMC)-secreted cytokines (secondary outcome) in individuals with overweight and obesity. Read More

View Article and Full-Text PDF

New nitric oxide-releasing indomethacin derivatives with 1,3-thiazolidine-4-one scaffold: Design, synthesis, in silico and in vitro studies.

Biomed Pharmacother 2021 May 5;139:111678. Epub 2021 May 5.

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, "Grigore T. Popa" University of Medicine and Pharmacy of Iași, 16 University Street, Iasi, Romania. Electronic address:

In this study we present design and synthesis of nineteen new nitric oxide-releasing indomethacin derivatives with 1,3-thiazolidine-4-one scaffold (NO-IND-TZDs) (6a-s), as a new safer and efficient multi-targets strategy for inflammatory diseases. The chemical structure of all synthesized derivatives (intermediaries and finals) was proved by NMR and mass spectroscopic analysis. In order to study the selectivity of NO-IND-TZDs for COX isoenzymes (COX-1 and COX-2) a molecular docking study was performed using AutoDock 4. Read More

View Article and Full-Text PDF

Molecular interaction between pectin and catechin/procyanidin in simulative juice model: Insights from spectroscopic, morphology, and antioxidant activity.

J Food Sci 2021 May 7. Epub 2021 May 7.

Shanghai Food Safety and Engineering Technology Research Center, Bor S. Luh Food Safety Research Center, Key Lab of Urban Agriculture Ministry of Agriculture, School of Agriculture & Biology, Shanghai Jiao Tong University, Shanghai, China.

The interactions between polysaccharides and phenolics in foods affect their physicochemical properties and bioactivity. Pectin and catechin/procyanidin present in plants ubiquitously and attracting more attentions for the potential health benefits. This work investigates the interactions between high methoxyl pectin and catechin/procyanidin in a simulative juice model using multiple microscopic and spectroscopic approaches and their influences on the antioxidant activity of phenolics were evaluated in the Caco-2 cells model. Read More

View Article and Full-Text PDF

Physical Exercise Training Improves Judgment and Problem-Solving and Modulates Serum Biomarkers in Patients with Alzheimer's Disease.

Mol Neurobiol 2021 May 7. Epub 2021 May 7.

Pharmacology Department, Federal University of Santa Catarina, Florianópolis, SC, Brazil.

Alzheimer's disease (AD) is characterized by progressive impairment of memory, with an etiology involving oxidative stress and inflammation. Exercise training is a safe, efficacious, and economic approach to manage neurodegenerative diseases. In AD, the biomarkers of oxidative damage to lipids, proteins, and DNA are elevated. Read More

View Article and Full-Text PDF

Effect of prenatal ambient temperature on the performance physiological parameters, and oxidative metabolism of Japanese quail (Coturnix coturnix japonica) layers exposed to heat stress during growth.

Sci Rep 2021 May 7;11(1):9809. Epub 2021 May 7.

Department of Animal Science, Federal University of Sergipe, São Cristóvão, Brazil.

A strategy to mitigate the negative effects of stress on animals is to enhance their ability to beneficially respond to stressful conditions. This study aimed to assess whether prenatal ambient temperature influences the response of Japanese quail (Coturnix coturnix japonica) chicks to environmental challenges during growth. The experiment was conducted in a 2 × 2 factorial arrangement: two temperature conditions for the mothers (thermoneutral and heat stress by continuous exposure to 32 °C) and two offspring ambient temperature conditions (thermoneutral and heat stress by intermittent exposure to 34 °C for 6 h/day from 15 to 35 days of age). Read More

View Article and Full-Text PDF

Fermentation transforms the phenolic profiles and bioactivities of plant-based foods.

Biotechnol Adv 2021 May 4:107763. Epub 2021 May 4.

School of Agriculture and Food, The University of Melbourne, Parkville, VIC 3010, Australia. Electronic address:

Phenolics are a group of compounds derived from plants that have displayed potent biological activities and health-promoting effects. Fermentation is one of the most conventional but still prevalent bioprocessing methods in the food industry, with the potential to increase phenolic content and enhance its nutritive value. This review details the biotransformation of different classes of phenolics (hydroxycinnamic and hydroxybenzoic acids, flavonoids, tannins, stilbenoids, lignans, alkylresorcinols) by various microorganisms (lactic acid bacteria, yeast, filamentous fungi) throughout the fermentation process in plant-based foods. Read More

View Article and Full-Text PDF

Photosynthesis Enhancement in Maize via Nontoxic Orange Carbon Dots.

J Agric Food Chem 2021 May 7. Epub 2021 May 7.

Institute for Multidisciplinary Research, University of Belgrade, 11000 Beograd, Serbia.

The sustained increase in leaf photosynthesis may increase crop yield. Due to many limitations, plants use much less photosynthetic capacity than is theoretically possible. Plant nanobionics investigates nanoparticle application in living plants, which improves certain plant functions. Read More

View Article and Full-Text PDF

Curcumin improves adipocytes browning and mitochondrial function in 3T3-L1 cells and obese rodent model.

R Soc Open Sci 2021 Mar 17;8(3):200974. Epub 2021 Mar 17.

Traditional Chinese Medicine School, Beijing University of Chinese Medicine, Beijing 100029, People's Republic of China.

Accumulating evidence suggests that mitochondrial dysfunction and adipocyte differentiation promote lipid accumulation in the development of obesity and diabetes. Curcumin is an active ingredient extracted from that has been shown to exhibit antioxidant and anti-inflammatory potency in metabolic disorders. However, the underlying mechanisms of curcumin in adipocytes remain largely unexplored. Read More

View Article and Full-Text PDF

Sea Cucumber-Derived Peptides Alleviate Oxidative Stress in Neuroblastoma Cells and Improve Survival in Exposed to Neurotoxic Paraquat.

Oxid Med Cell Longev 2021 19;2021:8842926. Epub 2021 Apr 19.

Cambridge Infinitus Research Centre, Department of Chemical Engineering and Biotechnology, University of Cambridge, West Cambridge Site, Philippa Fawcett Drive, Cambridge CB3 0AS, UK.

Oxidative stress results when the production of oxidants outweighs the capacity of the antioxidant defence mechanisms. This can lead to pathological conditions including cancer and neurodegeneration. Consequently, there is considerable interest in compounds with antioxidant activity, including those from natural sources. Read More

View Article and Full-Text PDF

Dietary Supplementation With Chlorogenic Acid Derived From Improves Meat Quality and Muscle Fiber Characteristics of Finishing Pigs via Enhancement of Antioxidant Capacity.

Front Physiol 2021 20;12:650084. Epub 2021 Apr 20.

Hunan Provincial Key Laboratory of Animal Intestinal Function and Regulation, Hunan International Joint Laboratory of Animal Intestinal Ecology and Health, Laboratory of Animal Nutrition and Human Health, School of Life Sciences, Hunan Normal University, Changsha, China.

Chlorogenic acid (CGA), one of the most abundant polyphenol compounds in nature, is regarded as a potential feed additive to promote animal health and enhance the meat products' quality via its various biological properties. The current study aims: (1) to determine whether dietary CGA supplementation improves meat quality and muscle fiber characteristics, and (2) to ascertain whether the corresponding improvement is associated with enhancing the antioxidant capacity of the finishing pigs. Thirty-two (Large × White × Landrace) finishing pigs with an average initial body weight of 71. Read More

View Article and Full-Text PDF

Antioxidant capacity of honey from the urban apiary: a comparison with honey from the rural apiary.

Sci Rep 2021 May 6;11(1):9695. Epub 2021 May 6.

Research Team of Animal Physiology and Ecotoxicology, Faculty of Natural Sciences, Institute of Biology, Biotechnology and Environmental Protection, University of Silesia, Bankowa 9, 40-007, Katowice, Poland.

Honey is a source of natural antioxidant compounds exerting several health-beneficial effects. Since urban beekeeping is quite common, the fear among potential consumers about the quality and the safety of honey produced exclusively in the cities is observed. However, the antioxidant properties of urban honey have not yet been tested. Read More

View Article and Full-Text PDF

Mesorhizobium ciceri as biological tool for improving physiological, biochemical and antioxidant state of Cicer aritienum (L.) under fungicide stress.

Sci Rep 2021 May 6;11(1):9655. Epub 2021 May 6.

Department of Botany and Microbiology, College of Science, King Saud University, P.O. Box 2455, Riyadh, 11451, Saudi Arabia.

Fungicides among agrochemicals are consistently used in high throughput agricultural practices to protect plants from damaging impact of phytopathogens and hence to optimize crop production. However, the negative impact of fungicides on composition and functions of soil microbiota, plants and via food chain, on human health is a matter of grave concern. Considering such agrochemical threats, the present study was undertaken to know that how fungicide-tolerant symbiotic bacterium, Mesorhizobium ciceri affects the Cicer arietinum crop while growing in kitazin (KITZ) stressed soils under greenhouse conditions. Read More

View Article and Full-Text PDF

Antioxidant and antimelanogenic activities of kimchi-derived JNU532 in B16F10 melanoma cells.

J Microbiol Biotechnol 2021 May 7;31(1). Epub 2021 May 7.

Division of Animal Science, Chonnam National University, Gwangju, 61186, Republic of Korea.

Melanin is a natural skin pigment produced by specialized cells called melanocytes via a multistage biochemical pathway known as melanogenesis, involving the oxidation and polymerization of tyrosine. Melanogenesis is initiated upon exposure to ultraviolet (UV) radiation, causing the skin to darken, which protects skin cells from UVB radiation damage. However, the abnormal accumulation of melanin may lead to the development of certain skin diseases, including skin cancer. Read More

View Article and Full-Text PDF

Probiotic red quinoa drinks for celiacs and lactose intolerant people: study of functional, physicochemical and probiotic properties during fermentation and gastrointestinal digestion.

Int J Food Sci Nutr 2021 May 6:1-11. Epub 2021 May 6.

Physiology Department, University of Murcia, Murcia, Spain.

The consumption of probiotic foods is rather limited for many sectors of the population (vegans, lactose intolerant and celiacs). Therefore, it is necessary to offer functional alternatives for these sectors. Different red quinoa drinks were fermented with (QLPBB) and (QBLBB) at different times. Read More

View Article and Full-Text PDF

Higher dietary total antioxidant capacity (TAC) reduces the risk of cardio-metabolic risk factors among adults: An updated systematic review and meta-analysis.

Int J Vitam Nutr Res 2021 May 7:1-15. Epub 2021 May 7.

Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.

Numerous studies have revealed the protective role of dietary antioxidants against hypertension and diabetes. In the current systematic review and meta-analysis, we evaluated the possible role of dietary total antioxidant capacity (TAC) against metabolic parameters in the adult population. A literature search of authentic electronic resources including PubMed, Scopus, Web of Sciences, and Cochrane had been performed to retrieve the qualified observational studies that reported the mean plus/minus the SD for the parameter in subjects of the highest versus lowest dietary TAC categories up to July 2020. Read More

View Article and Full-Text PDF

Novel strategy of natural antioxidant nutrition quality evaluation in food: Oxidation resistance mechanism and synergistic effects investigation.

Food Chem 2021 Apr 24;359:129768. Epub 2021 Apr 24.

Center for Advanced Analytical Science, School of Chemistry and Chemical Engineering c/o School of Civil Engineering, Guangzhou University, Guangzhou 510006, PR China; State Key Laboratory of Electroanalytical Chemistry, c/o Engineering Laboratory for Modern Analytical Techniques, CAS Center for Excellence in Nanoscience, Changchun Institute of Applied Chemistry, Changchun 130022, PR China; University of Chinese Academy of Sciences, Beijing 100039, PR China.

Effective evaluation methods for assessing the nutritional quality of foods that eliminate free radicals (i.e., foods that are classified as antioxidants) have long attracted the attention of scientists and the populace. Read More

View Article and Full-Text PDF

ROS and metabolomics-mediated autophagy in rat's testicular tissue alter after exercise training; Evidence for exercise intensity and outcomes.

Life Sci 2021 May 3:119585. Epub 2021 May 3.

Department of basic Sciences, Division of Histology & Embryology, Faculty of Veterinary Medicine, P.O.BOX: 1177, Urmia University, Urmia, Iran. Electronic address:

Aims: Oxidative damage and altered metabolic reactions are suspected to initiate the autophagy. The exercise training significantly impacts testicular antioxidant and metabolic potentials. However, the underlying mechanism(s) that the exercise-induced alterations can affect the autophagy markers remained unknown. Read More

View Article and Full-Text PDF

Effect of dietary flaxseed meal supplemented with dried tomato and grape pomace on performance traits and antioxidant status of laying hens.

Anim Biotechnol 2021 May 6:1-8. Epub 2021 May 6.

Department of DETO - Section of Veterinary Science and Animal Production, University of Bari "Aldo Moro", Valenzano, Italy.

This study was carried out to determine the effect of dietary flaxseed meal (FSM) supplemented with dried tomato pomace (DTP) and dried grape pomace (DGP) on performance, egg quality, biochemical parameters traits and antioxidant status of laying hens. Birds (1825 ± 87 g of body weight) were divided into 12 dietary groups with six replicates per group (eight birds per replicate), under a completely randomized design with factorial arrangement 2 × 3 × 2 consisted of two levels of DTP (0 and 15%), three FSM levels (0, 4 and 8%) and two levels of DGP (0 and 5%). As a result of this study, there were no significant differences in egg production and weight as well in feed conversion ratio (FCR) among treatments ( > 0. Read More

View Article and Full-Text PDF

Comparative study of gavage and intraperitoneal administration of gamma-oryzanol in alleviation/attenuation in a rat animal model of renal ischemia/reperfusion-induced injury.

Iran J Basic Med Sci 2021 Feb;24(2):175-183

Molecular Medicine Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Objectives: Ischemia/reperfusion (I/R) is the leading cause of acute kidney injury. This study aimed to elucidate the reno-protective effect of gamma-oryzanol (GO) by comparing gavage and intraperitoneal (IP) administration methods on renal I/R injury in a rat model.

Materials And Methods: Rats were divided into four groups including (group 1) sham, (group 2) I/R-control, (group 3) I/R+GO gavage-treated, and (group 4) I/R+ GO IP-treated. Read More

View Article and Full-Text PDF
February 2021

Protective effects of a standardized extract of on pancreas and liver in streptozotocin-induced diabetic rats.

Res Pharm Sci 2021 Feb 30;16(1):71-78. Epub 2020 Dec 30.

Pharmacological Research Center of Medicinal Plants, Mashhad University of Medical Sciences, Mashhad, I.R. Iran.

Background And Purpose: Previous studies have shown the antioxidant, anti-inflammatory, immunomodulatory, and hypolipidemic activities of . The aim of the present study was to evaluate the protective effects of hydroalcoholic extract of rhizomes on streptozotocin-induced diabetic rats.

Experimental Approach: Twenty-four male Wistar rats were randomly assigned into four groups including a normal control group, diabetic control group, diabetic groups treated for 4 weeks with 100 and 200 mg/kg/day of the extract (IGE). Read More

View Article and Full-Text PDF
February 2021

Drying methodology effect on the phenolic content, antioxidant activity of Myrtus communis L. leaves ethanol extracts and soybean oil oxidative stability.

BMC Chem 2021 May 5;15(1):31. Epub 2021 May 5.

Higher School of Food Industries of Tunis (ESIAT), University of Carthage, 58 Avenue Alain Savary, 1003, Tunis El Khadra, Tunisia.

In this study, different drying methodologies (convective air, oven and microwave) of Myrtus communis L. (M. communis L. Read More

View Article and Full-Text PDF

Use of lemongrass essential oil as a feed additive in quail's nutrition: its effect on growth, carcass, blood biochemistry, antioxidant and immunological indices, digestive enzymes and intestinal microbiota.

Poult Sci 2021 Mar 26;100(6):101172. Epub 2021 Mar 26.

Poultry Department, Faculty of Agriculture, Zagazig University, Zagazig 44511, Egypt.

The present study was designed to assess the impact of dietary supplementation of lemongrass essential oil (LGEO) on growth performance, carcass traits, liver and kidney function, immunity, antioxidant indices and caecal microbiota of growing quail. A total of 200 Japanese quails at 1-week-old were haphazardly allotted to 5 groups of 40 chicks in five replicates (8 per replicate). The first group was the control group, while LGEO was added at levels of 150, 300, 450, and 600 mg/kg diet in the 2nd, 3rd, 4th and 5th groups, respectively. Read More

View Article and Full-Text PDF

New markers of oxidative stress in lichen planus and the influence of hepatitis C virus infection - a pilot study.

Rom J Intern Med 2021 May 5. Epub 2021 May 5.

"Carol Davila" University of Medicine and Pharmacy, 37 Dionisie Lupu, 020021Bucharest, Romania.

Introduction: Lichen planus (LP) is a mucocutaneous T-cell mediated disorder of unknown etiology. There is growing evidence that oxidative stress is an important player in the pathogenesis of LP. Therefore, we have investigated oxidative stress markers in LP and the influence of hepatitis C virus (HCV) infection, a frequently associated condition, on oxidative stress in LP patients. Read More

View Article and Full-Text PDF

Combine effect of exposure to petrol, kerosene and diesel fumes: On hepatic oxidative stress and haematological function in rats.

Toxicol Ind Health 2021 May 5:7482337211012498. Epub 2021 May 5.

Cancer Immunology and Biotechnology Center, The University of Nottingham, Nottingham, UK.

Petroleum product fumes (PPFs) containing toxic organic components are pervasive in the environment, emanating from anthropogenic activities, including petroleum exploration and utilization by end-user activities from petrol-gasoline stations. Petrol station attendants are exposed to PPF through inhalation and dermal contact with consequent toxicological implications. We investigated the effects of chronic exposure (60 and 90 days) to petrol (P), kerosene (K) and diesel (D) alone and combined exposure to petrol, kerosene and diesel (PKD) fumes on hepatotoxicity, haematological function and oxidative stress in rats. Read More

View Article and Full-Text PDF

The comparison of the phytochemical composition, antioxidant and enzyme inhibition activity of two moss species: (Brid.) T. Kop. and Sull., from southwest ecological region in Turkey.

Nat Prod Res 2021 May 5:1-6. Epub 2021 May 5.

Department Science Education, Adnan Menderes University, Faculty of Education Mathematics and Science Education, Aydın, Turkey.

A limited number of mosses have been studied regarding antioxidant activity and enzyme inhibition effects. In the present study, the phytochemical content, antioxidant, and enzyme inhibition properties of the ether extracts from T.J. Read More

View Article and Full-Text PDF

UV-B exposure and exogenous hydrogen peroxide application lead to cross-tolerance toward drought in Nicotiana tabacum L.

Physiol Plant 2021 May 4. Epub 2021 May 4.

Biosystems Engineering, School of Engineering, Autonomous University of Queretaro-Campus Amazcala, Querétaro, Mexico.

Acclimation of plants to water deficit involves biochemical and physiological adjustments. Here, we studied how UV-B exposure and exogenously applied hydrogen peroxide (H O ) potentiates drought tolerance in tobacco (Nicotiana tabacum L. cv. Read More

View Article and Full-Text PDF

Preventive effect of Bacillus mojavensis levan against carbon tetrachloride and cisplatin toxicity: in vivo study.

Environ Sci Pollut Res Int 2021 May 5. Epub 2021 May 5.

Laboratory of Plants Improvement and Valorization of Agroressources, National School of Engineering of Sfax (ENIS), University of Sfax, 3038, Sfax, Tunisia.

This study is the first to investigate the hepato- and nephron-preventive effect of levan from Bacillus mojavensis (BM-levan) against toxicity induced by carbon tetrachloride (CCl) and cisplatin. Thirty-six male albino rats weighing between 230 and 250 g were used for this experiment. The groups received multiples doses of BM-levan and were compared to the untreated group. Read More

View Article and Full-Text PDF

Effect of pretreatment and temperature on the drying kinetics and physicochemical and techno-functional characteristics of pumpkin ().

Heliyon 2021 Apr 16;7(4):e06802. Epub 2021 Apr 16.

Universidad Nacional de Colombia, Facultad de Ciencias Agrarias, Departamento de Ingeniería Agrícola y Alimentos, Medellín, Colombia.

The study was carried out to assess fresh slices and thermally pretreated pumpkin () dried at temperatures of 55 °C, 60 °C, 65 °C, and 70 °C. The drying kinetics and quality attributes of the dried product were determined, and results indicated that the modified Page model was the best fit, with activation energies of 29.47 kJ mol and 16. Read More

View Article and Full-Text PDF

Sequential Changes in Antioxidant Potential of Oakleaf Lettuce Seedlings Caused by Nano-TiO Treatment.

Nanomaterials (Basel) 2021 Apr 29;11(5). Epub 2021 Apr 29.

Crop Physiology, Department of Plant Eco-Physiology, Faculty of Agriculture, University of Tabriz, Tabriz 5166616471, Iran.

Nowadays, there is an increasing interest in nanoparticle (NP) technology used in household and industrial products. It could cause an accumulation and dispersion of NPs in the environment, with possible harmful effects on living organisms. Nanoparticles significantly affect plants and alter their physiology and biochemical pathways, and nanotechnology can be used to improve plant characteristics that are desirable by humans. Read More

View Article and Full-Text PDF

Comparative Study between Exogenously Applied Plant Growth Hormones versus Metabolites of Microbial Endophytes as Plant Growth-Promoting for L.

Cells 2021 Apr 29;10(5). Epub 2021 Apr 29.

Department of Botany and Microbiology, Faculty of Science, Al-Azhar University, Nasr City, Cairo 11884, Egypt.

Microbial endophytes organize symbiotic relationships with the host plant, and their excretions contain diverse plant beneficial matter such as phytohormones and bioactive compounds. In the present investigation, six bacterial and four fungal strains were isolated from the common bean ( L.) root plant, identified using molecular techniques, and their growth-promoting properties were reviewed. Read More

View Article and Full-Text PDF