Cornea 2021 Apr 22. Epub 2021 Apr 22.
Ophthalmology, Visual Optics and Visual Rehabilitation, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium; Department of Ophthalmology, Antwerp University Hospital, Edegem, Belgium; Division of Ophthalmology, Department of Biomedical and Clinical Sciences, Faculty of Medicine, Linkoping University, Linköping, Sweden; and Department of Applied Physics, University of Zaragoza, Zaragoza, Spain.
Purpose: To assess the efficacy and safety of human leukocyte antigen-matched allogeneic cultivated limbal epithelial stem cell grafts in the treatment of aniridia-associated keratopathy (AAK).
Methods: Six eyes of 6 patients with severe AAK received an allogeneic stem cell graft between January 2010 and March 2017. Anatomical and functional results were assessed at 6 months, 1 year, 2 years, and the final follow-up visit available. Read More