5,192 results match your criteria angle progression


[Nonfusion procedures in pediatric scoliosis].

Orthopade 2021 May 5. Epub 2021 May 5.

Klinik für Orthopädie (Friedrichsheim), Universitätsklinikum Frankfurt, Marienburgstr. 2, 60528, Frankfurt am Main, Deutschland.

The treatment of early onset scoliosis (EOS) in children is a complex and demanding challenge in the treatment of spinal deformities. Conservative treatment with physiotherapy is indicated in mild forms with a Cobb angle from 10° and additionally a corset treatment with a Cobb angle of more than 20°. After exhaustion of the conservative measures or a progression of spinal scoliosis of 10° or deformities of more than 35°, a surgical approach should be considered in order to prevent respiratory insufficiency as well as severe postural and thoracic deformities. Read More

View Article and Full-Text PDF

Effect of Instrumentation Level on Mental Health Subscale of Scoliosis Research Society Outcomes Questionnaire in Adolescent Idiopathic Scoliosis.

Cureus 2021 Apr 1;13(4):e14234. Epub 2021 Apr 1.

Orthopaedics and Traumatology, Baltalimani Bone Diseases Research and Training Hospital, Istanbul, TUR.

Introduction Adolescent idiopathic scoliosis (AIS) surgery aims to obtain a flexible and stable spine, correct axial rotation and halt curve progression by fusing the least number of motion segments. Longer fusions can improve deformity correction, but late decompensation and lumbar degeneration may occur. Even some daily issues can be problematic in some scoliosis patients. Read More

View Article and Full-Text PDF

Quantification of dental macrowear using 3D occlusal surface topographic measurements in deciduous and permanent molars of children.

Am J Phys Anthropol 2021 May 4. Epub 2021 May 4.

Unit of Forensic Anthropology, Medical University of Vienna, Centre for Forensic Medicine, Vienna, Austria.

Objectives: Childhood paleodietary reconstruction via dental macrowear analysis is limited in part by available methods to measure dental macrowear. We describe a method to quantify dental macrowear progression (in both deciduous and permanent molars) using a handheld intraoral scanner and two 3D occlusal topographic measurements. We assess the agreement of our macrowear proxies with an established qualitative wear scoring system and their relationship to age. Read More

View Article and Full-Text PDF

Radiographic and plantar pressure assessment of pes planovalgus severity in children with cerebral palsy.

Clin Biomech (Bristol, Avon) 2021 Apr 27;85:105364. Epub 2021 Apr 27.

Department of Orthopedic Surgery, University of Colorado, Aurora, CO, USA; Center for Gait and Movement Analysis (CGMA), Children's Hospital Colorado, Aurora, CO, USA; Orthopedics Institute, Children's Hospital Colorado, Aurora, CO, USA.

Background: Pes planovalgus is common in children with cerebral palsy. Although severity influences treatment, there still lacks standard clinical measurements to objectively quantify pes planovalgus in this population. The comparison of pedobarographic data and radiographic measurements to clinical evaluation has not been reported in this population. Read More

View Article and Full-Text PDF

Modification and application of the proximal humerus ossification system to adolescent idiopathic scoliosis patients.

Spine Deform 2021 May 3. Epub 2021 May 3.

Division of Orthopedics, Texas Children's Hospital, Department of Orthopedics, Baylor College of Medicine, Houston, TX, 77030, USA.

Purpose: We have previously demonstrated that proximal humeral ossification patterns are reliable for assessing peak height velocity in growing patients. Here, we sought to modify the system by including medial physeal closure and evaluate whether this system combined with the Cobb angle correlates with progression to surgery in patients with adolescent idiopathic scoliosis.

Methods: We reviewed 616 radiographs from 79 children in a historical collection to integrate closure of the medial physis into novel stages 3A and 3B. Read More

View Article and Full-Text PDF

A Wearable Gait Analysis System Used in Type 2 Diabetes Mellitus Patients: A Case-Control Study.

Diabetes Metab Syndr Obes 2021 23;14:1799-1808. Epub 2021 Apr 23.

Department of Neurosurgery, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, People's Republic of China.

Background: Previous studies have shown that the gait of patients with type-2 diabetes mellitus is abnormal compared with the healthy group. Currently, a three-dimensional motion analyzer system is commonly used for gait analysis. However, it is challenging to collect data and use in clinical study due to extensive experimental conditions and high price. Read More

View Article and Full-Text PDF

Correlation between Radiological Outcome and Health Related Quality of Life after Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis.

J Nepal Health Res Counc 2021 Apr 23;19(1):44-47. Epub 2021 Apr 23.

Department of Orthopedics, Hospital and Rehablitation Center for Disabled Children (HRDC), Adhikari Gaoun, Ugratara VDC-6, Janagal, Kavre, Nepal.

Background: Posterior spinal surgery for adolescent idiopathic scoliosis is aimed at correcting deformity and stopping deformity progression to improve the health related quality of life. The correlation between radiological outcome and health related quality of life is yet unclear. This study aimed to assess the correlation between radiological outcome and health related quality of life. Read More

View Article and Full-Text PDF

Ten-year-and-beyond longitudinal change of ß-zone parapapillary atrophy in glaucoma: association with retinal nerve fibre layer defect.

Br J Ophthalmol 2021 Apr 30. Epub 2021 Apr 30.

Department of Ophthalmology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea

Background: To investigate the longitudinal change of localised retinal nerve fibre layer (RNFL) defects associated with change of ß-zone parapapillary atrophy (PPA) in primary open-angle glaucoma (POAG) eyes.

Methods: POAG patients with a localised RNFL defect and ß-zone PPA who had undergone disc/RNFL photography at 1-year intervals for 10 years or longer were enrolled. The topographic parameters of ß-zone PPA (area, maximal radial extent and angular extent around disc) were measured. Read More

View Article and Full-Text PDF

Glaucoma.

Med Clin North Am 2021 May 2;105(3):493-510. Epub 2021 Apr 2.

Department of Ophthalmology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. Electronic address:

Glaucoma is the leading cause of irreversible blindness worldwide. The global prevalence of glaucoma in people aged 40 to 80 years is estimated to be 3.5%. Read More

View Article and Full-Text PDF

The Potential Role of Small-Molecule PERK Inhibitor LDN-0060609 in Primary Open-Angle Glaucoma Treatment.

Int J Mol Sci 2021 Apr 26;22(9). Epub 2021 Apr 26.

Department of Clinical Chemistry and Biochemistry, Medical University of Lodz, 90-419 Lodz, Poland.

Primary open-angle glaucoma (POAG) constitutes the most common type of glaucoma. Emerging evidence suggests that Endoplasmic Reticulum (ER) stress and the protein kinase RNA-like endoplasmic reticulum kinase (PERK)-mediated Unfolded Protein Response (UPR) signaling pathway play a key role in POAG pathogenesis. Thus, the main aim of the study was to evaluate the effectiveness of the PERK inhibitor LDN-0060609 in cellular model of glaucoma using primary human trabecular meshwork (HTM) cells. Read More

View Article and Full-Text PDF

Study of the Distortion of the Indirect Angular Measurements of the Calcaneus Due to Perspective: In Vitro Testing.

Sensors (Basel) 2021 Apr 7;21(8). Epub 2021 Apr 7.

Department of Podiatry, Faculty of Nursing, Physiotherapy and Podiatry, Universidad de Sevilla, C/Avice-na s/n, 41009 Seville, Spain.

The study of the foot is relevant in kinematic analyses of gait. Images captured through a lens can be subjected to various aberrations or distortions that affect the measurements. An in vitro study was performed with a rearfoot simulator to compare the apparent degrees (photographed) with the real ones (placed in the simulator) in the plane of the rearfoot's orientation, according to variations in the capture angle in other planes of space (the sagittal plane and transverse plane-the latter determined by the foot progression angle). Read More

View Article and Full-Text PDF

Proximal Junctional Kyphosis in Adult Spinal Deformity: Definition, Classification, Risk Factors, and Prevention Strategies.

Asian Spine J 2021 Apr 30. Epub 2021 Apr 30.

Department of Orthopaedic Surgery, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.

Proximal junctional problems are among the potential complications of surgery for adult spinal deformity (ASD) and are associated with higher morbidity and increased rates of revision surgery. The diverse manifestations of proximal junctional problems range from proximal junctional kyphosis (PJK) to proximal junctional failure (PJF). Although there is no universally accepted definition for PJK, the most common is a proximal junctional angle greater than 10° that is at least 10° greater than the preoperative measurement. Read More

View Article and Full-Text PDF

Correlation of factors affecting correction of meniscal extrusion and outcome after medial meniscus root repair.

Arch Orthop Trauma Surg 2021 Apr 28. Epub 2021 Apr 28.

Ganga Hospital, 313, Mettupalayam Road, Coimbatore, 641043, India.

Introduction: Meniscus extrusion in medial meniscus posterior root tears (MMPRT) is a consistent MRI finding and correction of extrusion is a primary objective of the meniscal root repair. The purpose of the study is to evaluate feasibility of correction of extrusion and correlation of various factors affecting the postoperative extrusion correction and outcomes in all degenerative medial meniscus posterior roots (MMPRTs).

Methods: A retrospective study of patients who presented with degenerative MMPRTs following trivial incident (Jun 2014 and Aug 2018) and included isolated Laprade type 2 root tear with extrusion in MRI. Read More

View Article and Full-Text PDF

Can ultrasound on admission in active labor predict labor duration and a spontaneous delivery?: Condensation: Ultrasound at the beginning of the active phase can predict length of labor and mode of delivery in nulliparous women.

Am J Obstet Gynecol MFM 2021 Apr 23:100383. Epub 2021 Apr 23.

National Center for Fetal Medicine, St. Olavs hospital, Trondheim University Hospital, Trondheim, Norway; Department of Obstetrics and Gynecology, Stavanger University Hospital, Stavanger, Norway; Institute of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.

Background: Identifying predictive factors for a normal outcome at admission in the labor ward would be of value for planning labor care, timing interventions and in preventing labor dystocia. Clinical assessments of fetal head station and position at the start of labor have some predictive value but the value of ultrasound methods for this purpose has not been investigated. Studies using transperineal ultrasound before labor onset show possibilities of using these methods to predict outcome. Read More

View Article and Full-Text PDF

Development and validation of circulating tumour cell enumeration (Epic Sciences) as a prognostic biomarker in men with metastatic castration-resistant prostate cancer.

Eur J Cancer 2021 Apr 21;150:83-94. Epub 2021 Apr 21.

Duke Cancer Institute Center for Prostate and Urologic Cancers, Duke University, Durham, NC, USA; Department of Biostatistics and Bioinformatics, Duke University, Durham, NC, USA.

Purpose: To evaluate the prognostic significance of circulating tumour cell (CTC) number determined on the Epic Sciences platform in men with metastatic castration-resistant prostate cancer (mCRPC) treated with an androgen receptor signalling inhibitor (ARSI).

Patients And Methods: A pre-treatment blood sample was collected from men with progressing mCRPC starting either abiraterone or enzalutamide as a first-, second- or third-line systemic therapy at Memorial Sloan Kettering Cancer Center (Discovery cohort, N = 171) or as a first- or second-line therapy as part of the multicenter PROPHECY trial (NCT02269982) (Validation cohort, N = 107). The measured CTC number was then associated with overall survival (OS) in the Discovery cohort, and progression-free survival (PFS) and OS in the Validation cohort. Read More

View Article and Full-Text PDF

Functional and Radiographic Disease Progression in Nonoperatively Managed Kienböck Disease.

Plast Reconstr Surg 2021 May;147(5):1117-1123

From the Department of Plastic and Orthopedic Surgery, University of Virginia; the Department of Orthopaedics and Sports Medicine, University of Washington; and the Department of Orthopedic Surgery, Mayo Clinic.

Background: The purpose of this study was to describe the natural history of Kienböck disease among patients who elected to proceed with nonoperative treatment.

Methods: The authors performed a retrospective study of all patients treated nonoperatively for Kienböck disease within their institution from January 1, 1999, to December 31, 2014. Inclusion criteria included follow-up greater than 1 year, serial posteroanterior and lateral wrist radiographs, and clinical examination. Read More

View Article and Full-Text PDF

Surgical Outcome of Laminoplasty for Cervical Spondylotic Myelopathy: A Single-Institution Experience.

Turk J Med Sci 2021 Apr 23. Epub 2021 Apr 23.

Background/aim: Cervical spondylotic myelopathy (CSM) develops as a result of compression of the spinal cord in the cervical region. Early diagnosis and surgical treatment can limit the progression of symptoms. Various surgical approaches and strategies have been described in the literature. Read More

View Article and Full-Text PDF

Effects of 8 years of growth hormone treatment on scoliosis in children with Prader-Willi syndrome.

Eur J Endocrinol 2021 Apr 1. Epub 2021 Apr 1.

A Hokken-Koelega, Department of Pediatrics, Subdivision of Endocrinology, Dutch Growth Research Foundation , Rotterdam, Netherlands.

Objective: Scoliosis is frequently seen in children with Prader-Willi syndrome (PWS). There is still concern that growth hormone (GH) treatment might increase the risk of onset or progression of scoliosis. Short-term data suggested no adverse effects of GH on scoliosis, but long-term effects of GH treatment on development of scoliosis in PWS are unknown. Read More

View Article and Full-Text PDF

Treatment of Open-Angle Glaucoma and Ocular Hypertension with Preservative-Free Tafluprost/Timolol Fixed-Dose Combination Therapy: UK and Ireland Results from the VISIONARY Study.

Adv Ther 2021 Apr 22. Epub 2021 Apr 22.

Royal Victoria Infirmary, The Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.

Introduction: Reducing intraocular pressure (IOP), the only modifiable risk factor for open-angle glaucoma (OAG), is important for the preservation of vision and slowing of disease progression. Preservative-free tafluprost (0.0015%)/timolol (0. Read More

View Article and Full-Text PDF

Bilateral angle-closure during hospitalization for coronavirus disease-19 (COVID-19): A case report.

Eur J Ophthalmol 2021 Apr 22:11206721211012197. Epub 2021 Apr 22.

Department of Neurosciences, Biomedicine and Movement Sciences, Eye Clinic, University of Verona, Verona, Italy.

Purpose: This report describes a case of bilateral primary angle closure (PAC) progressing to unilateral end-stage primary angle closure glaucoma (PACG) associated with treatment for coronavirus disease-19 (COVID-19) infection.

Methods: A 64-year-old man came to our attention because of blurred vision after a 2-month hospital stay for treatment of COVID-19 infection. Examination findings revealed PACG, with severe visual impairment in the right eye and PAC in the left eye due to plateau iris syndrome. Read More

View Article and Full-Text PDF

Effect of curve location on the severity index for adolescent idiopathic scoliosis: a longitudinal cohort study.

Eur Radiol 2021 Apr 21. Epub 2021 Apr 21.

Arts et Métiers Institute of Technology, Université Sorbonne Paris Nord, IBHGC - Institut de Biomécanique Humaine Georges Charpak, HESAM Université, 151 bd de l'Hôpital, F-75013, Paris, France.

Objectives: Adolescent idiopathic scoliosis (AIS) is the most common spinal disorder in children. A severity index was recently proposed to identify the stable from the progressive scoliosis at the first standardized biplanar radiographic exam. The aim of this work was to extend the validation of the severity index and to determine if curve location influences its predictive capabilities. Read More

View Article and Full-Text PDF

Measuring optic nerve head perfusion to monitor glaucoma: a study on structure-function relationships using laser speckle flowgraphy.

Acta Ophthalmol 2021 Apr 20. Epub 2021 Apr 20.

Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.

Purpose: We aimed to describe the global and localized correlations among visual field (VF) sensitivity, optic nerve head (ONH) perfusion measured by laser speckle flowgraphy (LSFG) and neural structure measured by optical coherence tomography (OCT) in open-angle glaucoma (OAG) and to compare the floor effect for LSFG and OCT.

Methods: Cross-sectional, multicenter study including one eye each from fifty OAG patients (mean age 69.3 years; average VF mean deviation, MD, -8. Read More

View Article and Full-Text PDF

Long-term follow-up of the three-ligament tenodesis for scapholunate ligament lesions: 9-year results.

Hand Surg Rehabil 2021 Apr 18. Epub 2021 Apr 18.

UZ Leuven, Department of Orthopedic Surgery, Herestraat 49, 3000 Leuven, Belgium. Electronic address:

We report on a retrospective cohort of 50 cases of three-ligament tenodesis for scapholunate instability. Fifteen cases (30% of our cohort) needed salvage surgery (11 proximal row carpectomies, 2 partial and 2 total wrist fusions) at an average of 33 months and are considered "failures". Of the 35 remaining cases ("success"), 16 (32% of our cohort) were reviewed at average 111 months and had good functional outcomes (QuickDASH 18/100, PRWE 11/100, pain 1/10, satisfaction 9/10). Read More

View Article and Full-Text PDF

Patellofemoral and tibiofemoral joint loading during a single-leg forward hop following ACL reconstruction.

J Orthop Res 2021 Apr 19. Epub 2021 Apr 19.

La Trobe Sports & Exercise Medicine Research Centre, La Trobe University, Melbourne, Victoria, Australia.

Altered biomechanics are frequently observed following anterior cruciate ligament reconstruction (ACLR). Yet, little is known about knee-joint loading, particularly in the patellofemoral-joint, despite patellofemoral-joint osteoarthritis commonly occurring post-ACLR. This study compared knee-joint reaction forces and impulses during the landing phase of a single-leg forward hop in the reconstructed knee of people 12-24 months post-ACLR and uninjured controls. Read More

View Article and Full-Text PDF

Challenge for management without tracheostomy tube after laryngo-tracheal separation in children with neurological disorders.

Laryngoscope Investig Otolaryngol 2021 Apr 6;6(2):332-339. Epub 2021 Feb 6.

Department of General Pediatrics and Interdisciplinary medicine National Center for Child Health and Development Tokyo Japan.

Objectives: The present study analyzed surgical outcomes of laryngotracheal separation (LTS) in children with neurological disorders. The purpose of this study was to investigate respiratory impairment and severe complications after LTS in children, and identify the possibility of permanent tracheostomy without a tracheostomy tube as the safest respiratory management method.

Methods: Twenty-eight patients (male:female = 16:12) with neurological disorders (6 months to 32 years) who underwent LTS between January 2012 and April 2018 were reviewed. Read More

View Article and Full-Text PDF

Analysis of Gait Motion Changes by Intervention Using Robot Suit Hybrid Assistive Limb (HAL) in Myelopathy Patients After Decompression Surgery for Ossification of Posterior Longitudinal Ligament.

Front Neurorobot 2021 31;15:650118. Epub 2021 Mar 31.

Department of Orthopaedic Surgery, University of Tsukuba, Tsukuba, Japan.

Ossification of the posterior longitudinal ligament (OPLL) is a hyperostonic condition in which the posterior longitudinal ligament becomes thick and loses its flexibility, resulting in ectopic ossification and severe neurologic deficit (Matsunaga and Sakou, 2012). It commonly presents with myelopathy and radiculopathy and with myelopathy progression motor disorders and balance disorders can appear. Even after appropriate surgical decompression, some motor impairments often remain. Read More

View Article and Full-Text PDF

Rapid growth of primary uveal melanoma following intravitreal bevacizumab injection: a case report and review of the literature.

Digit J Ophthalmol 2021 Feb 3;26(3):27-30. Epub 2020 Jul 3.

Department of Ophthalmology and Visual Sciences, University of Alberta, Edmonton, Alberta, Canada.

Uveal melanoma size is a significant predictor of tumor metastasis. Although the relationship between antivascular endothelial growth factors (VEGF) and uveal melanoma growth has been studied, results are paradoxical, and the relationship remains controversial. We report the case of a 65-year-old man who presented with elevated intraocular pressure in his right eye, neovascularization of his iris, and significant corneal edema, which obscured the view of the angle. Read More

View Article and Full-Text PDF
February 2021

Detecting Progression in Patients with Different Clinical Presentations of Primary Open-angle Glaucoma.

J Glaucoma 2021 Apr 12. Epub 2021 Apr 12.

Department of Ophthalmology and Visual Sciences, University of Alabama at Birmingham, AL 35233, USA Computational Optometry, Atarfe, Spain.

Prcis: Glaucoma progression was more frequently identified by assessing retinal fiber layer thickness than by monitoring visual field loss for different baseline classifications in primary open-angle glaucoma.

Purpose: To compare the detection of glaucoma progression by retinal nerve fiber layer thickness (RNFLT) and visual field (VF) assessments for different baseline classifications of primary open-angle glaucoma (POAG).

Methods: This study included 194 eyes from 194 patients with a minimum of 9 follow-up visits selected from the Diagnostic Innovation in Glaucoma Study and the African Descent and Glaucoma Evaluation Study. Read More

View Article and Full-Text PDF

Baseline Choroidal Microvasculature Dropout as a Predictor of Subsequent Visual Field Progression in Open-Angle Glaucoma.

J Glaucoma 2021 Apr 15. Epub 2021 Apr 15.

Department of Ophthalmology, Konkuk University Medical Center, Seoul, Korea Department of Ophthalmology, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea.

Precis: CMvD is an independet predictor for overall and central visual field progression in OAG eyes.

Purpose: To investigate the impact of choroidal microvasculature dropout (CMvD) identified by optical coherence tomography angiography (OCT-A) at baseline on subsequent visual field (VF) progression in eyes with open-angle glaucoma (OAG).

Materials And Methods: This retrospective observational study included 80 OAG eyes with CMvD [CMvD(+)] and without CMvD [(CMvD(-)] at baseline (40 of each matched for both age [≤ 10▒y] and baseline VF severity [≤ 1▒dB]). Read More

View Article and Full-Text PDF

Outcomes After Corneal Crosslinking for Keratoconus in Children and Young Adults.

Cornea 2021 Apr 14. Epub 2021 Apr 14.

Byers Eye Institute, Stanford University School of Medicine, Palo Alto, CA.

Purpose: The aim of this study was to assess the effect of corneal crosslinking on vision and keratometry in children and young adults with progressive keratoconus.

Methods: A retrospective medical records review of patients aged 22 years or younger with keratoconus who underwent corneal crosslinking between January 2013 and November 2019 at Byers Eye Institute at Stanford University was conducted. Outcome measures included logarithm of the Minimum Angle of Resolution corrected distance visual acuity (CDVA); keratometry, including maximum keratometry (Kmax); pachymetry; and total wavefront aberration. Read More

View Article and Full-Text PDF