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Alginate/gelatin-based hybrid hydrogels with function of injecting and encapsulating cells in situ.

Int J Biol Macromol 2022 May 16. Epub 2022 May 16.

School of Chemistry and Life Science, Suzhou University of Science and Technology, Suzhou 215009, China.

Multi-network hydrogels with high strength and toughness have attracted increasing attention. Herein, a hybrid hydrogel consisting of alginate, gelatin, and polyacrylamide was constructed with the combination of advantages of natural and synthetic polymers. Alginate grafted with host-guest complex of βCD/Ad-AAm was first prepared, namely Alg-βCD/Ad-AAm, then further crosslink with gelatin methacryloyl (GelMA) to form hydrogel via one-step UV light initiation. Read More

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Preparing guiding planes for removable partial dentures: comparison between assisted CAD-CAM template procedure and freehand preparation: An in vitro study.

J Dent 2022 May 16:104166. Epub 2022 May 16.

Center of Digital Dentistry, Faculty of Prosthodontics, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices & Beijing Key Laboratory of Digital Stomatology & Shanxi Province Key Laboratory of Oral Diseases Prevention and New Materials, Beijing, PR China. Electronic address:

Objectives: To compare the trueness of computer-aided design and computer-aided manufacturing (CAD-CAM) assisted procedure and freehand procedure for preparing guiding planes for removable partial dentures (RPDs).

Methods: Forty identical mandibular resin casts were divided into two groups in which the guiding planes of two abutment teeth were prepared freehand (control group, n = 20) and using rigidly constrained templates (test group, n = 20). The template was designed on a digital cast of virtually prepared guiding planes and fabricated by selective laser melting using cobalt-chromium alloy. Read More

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Sacral Slope Change from Standing to Relaxed-Seated Grossly Overpredicts the Presence of a Stiff Spine.

J Arthroplasty 2022 May 16. Epub 2022 May 16.

Melbourne Orthopaedic Group, 33 The Avenue, Windsor VIC 3181, Melbourne, Australia.

Introduction: Several authors propose that a change in sacral slope of ≤10° between the standing and relaxed-seated positions (ΔSS) identifies a patient with a stiff lumbar spine and have suggested use of dual-mobility bearings for such patients undergoing a total hip arthroplasty (THA). The aim of this study was to assess how accurately ΔSS can identify patients with a stiff spine.

Methods: A prospective, multi-centre, consecutive cohort series of 312 patients had standing, relaxed-seated and flexed-seated lateral radiographs prior to THA. Read More

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Multiview behavior and neurotransmitter analysis of zebrafish dyskinesia induced by 6PPD and its metabolites.

Sci Total Environ 2022 May 16:156013. Epub 2022 May 16.

College of Sciences, China Agricultural University, Beijing 100193, China.

The typical tire manufacturing additive 6PPD, its metabolites 6PPDQ and 4-Hydroxy should be monitored because of their ubiquitous presence in the environment and the high toxicity of 6PPDQ to coho salmon. The toxic effect of 6PPD and its metabolites have been revealed superficially, especially on behavioral characteristics. However, the behavioral indicators explored so far are relatively simple and the toxic causes are poorly understood. Read More

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Difference in the Cobbs Angle Between Standing and Supine Position as a Prognostic Factor After Vertebral Augmentation in Osteoporotic Vertebral Compression Fractures.

Neurospine 2022 May 17. Epub 2022 May 17.

Department of Neurosurgery, Uijeongbu Eulji Medical Center, Eulji University, Uijeongbu, Korea.

Objective: We retrospectively analyzed patients with osteoporotic vertebral compression fracture (OVCF) undergoing vertebral augmentation to compare the Cobbs angle changes in the supine and standing positions and the clinical outcomes.

Methods: We retrospectively extracted the data of OVCF patients who underwent vertebral augmentation. Back pain was assessed using a visual analog scale (VAS). Read More

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Photonic Bandgap Engineering in (VO)/(WSe)Photonic Superlattice for Versatile Near- and Mid-Infrared Phase Transition Applications.

J Phys Condens Matter 2022 May 19. Epub 2022 May 19.

Selcuk Universitesi, Meram, Konya, Konya, Konya, 42130, TURKEY.

The application of the photonic superlattice in advanced photonics has become a demanding field, especially for two-dimensional and strongly correlated oxides. Because it experiences an abrupt metal-insulator transition (MIT) near ambient temperature, where the electrical resistivity varies by orders of magnitude, vanadium oxide (VO) shows potential as a building block for infrared switching and sensing devices. We reported a first principle study of superlattice structures of VOas a strongly correlated phase transition material and tungsten diselenide (WSe) as a 2-dimensional transition metal dichalcogenide (TMD) layer. Read More

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3D printed auxetic heel pads for patients with diabetic mellitus.

Comput Biol Med 2022 May 5;146:105582. Epub 2022 May 5.

Hong Kong Community College, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China.

More than 422 million people worldwide suffered from diabetes mellitus (DM) in 2021. Diabetic foot is one the most critical complications resultant of DM. Foot ulceration and infection are frequently arisen, which are associated with changes in the mechanical properties of the plantar soft tissues, peripheral arterial disease, and sensory neuropathy. Read More

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A low-cost flow cell for flow cytometry.

Biosens Bioelectron 2022 May 10;211:114334. Epub 2022 May 10.

IIT Bombay, Department of Chemical Engineering, IIT Bombay, Powai, Mumbai, 400076, Maharashtra, India. Electronic address:

Flow cytometry is an essential analytical technique used in biomedical diagnostics to measure properties of cells, micro-organisms, and particles. Laser light is scattered from particles focused in a flow cell and collected by light sensors, where the intensity of the scattered light is a function of the scattering angle, the refractive index of the particle and surrounding medium, the wavelength of light, and the size and the shape of the particle. One of the critical parts of the cytometer is the flow cell where the particle stream is constrained into a tight region within 10-30 μm using hydrodynamic focusing. Read More

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Rapid variable flip angle positive susceptibility contrast imaging for clinical metal seeds.

J Magn Reson 2022 Apr 30;340:107232. Epub 2022 Apr 30.

Paul C. Lauterbur Research Centre for Biomedical Imaging, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, China. Electronic address:

Positive susceptibility contrast imaging (PSCI) based on susceptibility mapping exhibits excellent efficacy for visualizing magnetic resonance (MR)-compatible metallic devices because of their high magnetic susceptibility compared to that of human tissues. However, the long-acquisition time required by the two-dimensional fast spin echo (2D FSE)-based PSCI approach, impedes its practical applications in 3D imaging. In this study, a three-dimensional (3D) susceptibility-based variable flip angle (vFA) FSE sequence was proposed to accelerate data acquisition in the clinical radiotherapy applications of ex vivo and in vivo rapid 3D PSCI for the imaging of metal seeds. Read More

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Elongation of the inferior rectus tendon with fascia lata graft for large vertical squint angles in patients with Graves' orbitopathy.

Graefes Arch Clin Exp Ophthalmol 2022 May 19. Epub 2022 May 19.

Department of Ophthalmology, RWTH Aachen University, 52074, Aachen, Germany.

Purpose: To investigate the use of fascia lata (FL) grafts for inferior rectus muscle (IRM) tendon elongation in patients with large vertical squint angles with Graves' orbitopathy (GO).

Methods: In this retrospective study, we included a consecutive series of 20 eyes of 13 patients with GO who underwent IRM tendon elongation with FL. Orthoptic and ophthalmologic examinations including measurement of the head posture, the extent of deviation in primary position (PP), elevation, motility, and binocular diplopia at the tangent of Harms were conducted preoperatively and after a mean postoperative time of 10. Read More

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Four-Dimensional computed tomography of the left ventricle, Part I: motion artifact reduction.

Med Phys 2022 May 19. Epub 2022 May 19.

Department of Bioengineering, UC San Diego School of Engineering, La Jolla, CA 92037-0412, USA.

Purpose: Standard 4DCT cardiac reconstructions typically include spiraling artifacts that depend not only on the motion of the heart, but also on the gantry angle range over which the data was acquired. We seek to reduce these motion artifacts and thereby improve the accuracy of left ventricular wall positions in 4DCT image series.

Methods: We use a motion artifact reduction approach (ResyncCT) that is based largely on conjugate pairs of partial angle reconstruction images (PARs). Read More

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Impact of Perioperative Dry Eye Treatment with Rebamipide Versus Artificial Tears on Visual Outcomes After Cataract Surgery in Japanese Population.

Ophthalmol Ther 2022 May 19. Epub 2022 May 19.

Department of Ophthalmology, Yokohama City University School of Medicine, Kanazawa, Yokohama, Kanagawa, Japan.

Introduction: The present study aimed to compare the effects of rebamipide and artificial tears during the perioperative period of cataract surgery on the postoperative visual outcomes.

Methods: Seventy-two eyes from 36 patients with a cataract were enrolled. Rebamipide (group R) was administered in one eye and Mytear® artificial tear ophthalmic solution (group A) in the other eye from 4 weeks preoperatively to 3 months postoperatively. Read More

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Association of Diabetes Medication With Open-Angle Glaucoma, Age-Related Macular Degeneration, and Cataract in the Rotterdam Study.

JAMA Ophthalmol 2022 May 19. Epub 2022 May 19.

Department of Ophthalmology, Erasmus University Medical Center, Rotterdam, the Netherlands.

Importance: Recent studies suggest that the diabetes drug metformin has a protective effect on open-angle glaucoma (OAG) and age-related macular degeneration (AMD). However, studies have not addressed the critical issue of confounding by indication, and associations have not been evaluated in a large prospective cohort.

Objective: To determine the association between diabetes medication and the common eye diseases OAG, AMD, and cataract and to evaluate their cumulative lifetime risks in a large cohort study. Read More

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A Combined Assessment Method of Phase Angle and Skeletal Muscle Index to Better Predict Functional Recovery after Acute Stroke.

J Nutr Health Aging 2022 ;26(5):445-451

Yoshihiro Yoshimura, Kumamoto Rehabilitation Hospital, Kikuchi, Kumamoto Japan,

Objectives: We aimed to investigate whether combination assessment of phase angle (PhA) and skeletal muscle index (SMI), was a possible predictor of physical function at discharge from the hospital in patients with acute stroke.

Research Methods And Procedures: In this retrospective cohort study that was conducted from May 2020 and July 2021, we determined PhA and SMI using bioimpedance analysis (BIA) in patients with acute stroke. Patients were classified as normal, low PhA + SMI group, pre-sarcopenia (low SMI only), and dynapenia (low PhA only) using cut-off points (men: SMI < 7. Read More

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January 2022

Stable O/W emulsions and oleogels with amphiphilic konjac glucomannan network: Preparation, characterization, and application.

J Sci Food Agric 2022 May 19. Epub 2022 May 19.

Fujian Agriculture and Forestry University, Fuzhou, Fujian, 350002, China.

Background: The stabilization of O/W emulsions has long been explored. Assembly of polymer networks is an effective method for stabilizing O/W emulsions. Konjac glucomannan (KGM) is a plant polysaccharide and the network of KGM gel is one of the good candidates for stabilizing O/W emulsions based on its high viscosity and thickening properties. Read More

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Within-person variability contributes to more durable learning of faces.

Can J Exp Psychol 2022 May 19. Epub 2022 May 19.

Department of Psychology.

Exposure to the natural, unsystematic within-person variability present across different encounters with a face (e.g., differences in emotion, makeup, and hairstyle) increases the likelihood the face will be recognized despite changes in appearance. Read More

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Finite element analysis of 3D-printed personalized titanium plates for mandibular angle fracture.

Comput Methods Biomech Biomed Engin 2022 May 19:1-12. Epub 2022 May 19.

Department of Oral and Maxillofacial Surgery, The Second Hospital of Shandong University, Jinan, Shandong Province, People's Republic of China.

This paper discussed the size of 3 D-printed personalized titanium plates that can gain maximum stability of mandibular fracture and minimize stress shielding through finite element analysis. A 3 D virtual model of mandible with mandibular angle fracture was created from the CT data of patient. 3 D-printed personalized titanium plates varying in length and thickness were designed, and finite element analysis was performed under different loading conditions and fracture healing periods. Read More

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Design and Development of a Disposable Superfine Catheter for Visual Examination of Bile Ducts and Related Animal Experiments.

Front Surg 2022 2;9:877040. Epub 2022 May 2.

Department of Gastroenterology, Lanzhou University Second Hospital, Lanzhou, Gansu, China.

Objective: To design and develop a disposable superfine catheter system for visual examination of bile and pancreatic ducts and predict its clinical application value.

Methods: The superfine triple-lumen catheter and miniature photography technology were used to design and produce a disposable superfine catheter for visual examination of bile and pancreatic ducts, and animal experiments were conducted to compare said catheter and SpyGlass™.

Results: The designed and developed disposable superfine catheter for visual examination of bile ducts with a diameter of 2. Read More

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A field test of forest canopy structure measurements with the CanopyCapture smartphone application.

PeerJ 2022 13;10:e13450. Epub 2022 May 13.

Environmental Research Institute, University of Waikato, Hamilton, New Zealand.

Background: Several smartphone applications have been developed for the purpose of low-cost and convenient assessments of vegetation canopy structure and understorey illumination. Like standard hemispherical photography, most of these applications require user decisions about image processing, posing challenges for repeatability of measurements. Here I report a test of CanopyCapture, an application that instantaneously estimates percentage canopy gap fraction without any input from the user, and has the added advantage of an intuitive levelling mechanism. Read More

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Platelet Parameters and Their Relationships With the Thickness of the Retinal Nerve Fiber Layer and Ganglion Cell Complex in Primary Open-Angle Glaucoma.

Front Neurol 2022 2;13:867465. Epub 2022 May 2.

Department of Ophthalmology and Visual Science, Shanghai Medical College, Eye and Ear Nose and Throat Hospital, Fudan University, Shanghai, China.

Objective: Glaucoma is a neurodegenerative disease of the visual system. Platelet parameters are correlated with visual field mean deviation (MD) in glaucoma, but there is a lack of relative data on their relationship with structural changes in the retina. This study aimed to explore the relationship between platelet parameters and retinal nerve fiber layer (RNEL), ganglion cell complex (GCC) thickness, and cup/disk area ratio, evaluated by optical coherence tomography (OCT) in primary open-angle glaucoma (POAG). Read More

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Silica Particle-Mediated Growth of Single Crystal Graphene Ribbons on Cu(111) Foil.

Small 2022 May 18:e2202536. Epub 2022 May 18.

Center for Multidimensional Carbon Materials (CMCM), Institute for Basic Science (IBS), Ulsan, 44919, Republic of Korea.

The authors report the growth of micrometer-long single-crystal graphene ribbons (GRs) (tapered when grown above 900 °C, but uniform width when grown in the range 850 °C to 900 °C) using silica particle seeds on single crystal Cu(111) foil. Tapered graphene ribbons grow strictly along the Cu<101> direction on Cu(111) and polycrystalline copper (Cu) foils. Silica particles on both Cu foils form (semi-)molten Cu-Si-O droplets at growth temperatures, then catalyze nucleation and drive the longitudinal growth of graphene ribbons. Read More

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Clinical characteristics of comorbid retinal dystrophies and primary angle closure disease.

Int Ophthalmol 2022 May 18. Epub 2022 May 18.

VST Center for Glaucoma Care, L V Prasad Eye Institute, Hyderabad, Telangana, India.

Purpose: To assess the clinical characteristics of comorbid retinal dystrophies and primary angle closure disease.

Design: Retrospective study from January 1992 to June 2020.

Methods: This descriptive study included 92 eyes of 46 patients with comorbid retinal dystrophies and primary angle closure disease (PACD) that included eyes with primary angle closure suspect, primary angle closure and primary angle closure glaucoma. Read More

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Direct observation of the dead-cone effect in quantum chromodynamics.

Authors:

Nature 2022 May 18;605(7910):440-446. Epub 2022 May 18.

In particle collider experiments, elementary particle interactions with large momentum transfer produce quarks and gluons (known as partons) whose evolution is governed by the strong force, as described by the theory of quantum chromodynamics (QCD). These partons subsequently emit further partons in a process that can be described as a parton shower, which culminates in the formation of detectable hadrons. Studying the pattern of the parton shower is one of the key experimental tools for testing QCD. Read More

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Pediatric vestibular schwannoma without evidence of neurofibromatosis: consecutive 18 microsurgical experiences.

Childs Nerv Syst 2022 May 19. Epub 2022 May 19.

Department of Neurosurgery, Tokyo Metropolitan Police Hospital, Tokyo, Japan.

Purpose: Sporadic vestibular schwannoma (VS) is rare in children in contrast to adults, and detailed investigations of case series of these patients using a single fixed protocol are scarce. This study presents our surgical experience of pediatric VSs without clinical evidence of neurofibromatosis type 2 (NF2) at the initial diagnosis.

Methods: Among 1385 consecutive sporadic VS surgeries, 18 pediatric patients (1. Read More

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The effects of biomechanical factors on adjacent vertebral compression fractures after percutaneous kyphoplasty: a propensity score matching analysis.

Osteoporos Int 2022 May 18. Epub 2022 May 18.

Department of Spine Surgery, The Affiliated Hospital of Qingdao University, No.59 Haier Road, Qingdao, 266000, Shandong, China.

Adjacent vertebral compression fracture (AVCF) is the primary factor affecting satisfaction after PKP surgery. In addition to osteoporosis, certain structural characteristics of the vertebral body itself also increase their risk. The purpose of this study was to explore the impact of biomechanical changes on AVCF after balancing other factors. Read More

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Effect of PEG grafting density on surface properties of polyurethane substrata and the viability of osteoblast and fibroblast cells.

J Mater Sci Mater Med 2022 May 18;33(6):45. Epub 2022 May 18.

A.C, Unidad de Materiales, Calle 43 No. 130, Centro de Investigación Científica de Yucatán, Col. Chuburná de Hidalgo, C.P. 97205, Mérida, Yucatán, México.

The surface of Tecoflex SG-80A Polyurethane (PU) films was modified by grafting polyethylene glycol (PEG) chains at three different molar amounts (0.05, 0.10, and 0. Read More

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Clinical Outcomes of Supramalleolar Osteotomy in Intermediate Stage of Varus Ankle Osteoarthritis in Joint Preservation.

J Foot Ankle Surg 2022 Apr 10. Epub 2022 Apr 10.

Department of Orthopedic Surgery, College of Medicine, Kyung Hee University, Seoul, Korea. Electronic address:

Supramalleolar osteotomy (SMO) is an effective treatment for intermediate-stage varus ankle osteoarthritis (OA). This study aimed to investigate how clinical outcomes were associated with radiological changes and cartilage regeneration shown on arthroscopy before and after SMO in patients with intermediate-stage varus ankle OA. Twenty-six cases with intermediate-stage varus ankle OA underwent SMO with at least 1 year of postoperative follow-up. Read More

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A Biomimetic High Throughput Model of Cancer Cell Spheroid Dissemination onto Aligned Fibrillar Collagen.

SLAS Technol 2022 May 15. Epub 2022 May 15.

School of Physics, University College Dublin, Belfield, Dublin 4, D04 V1W8, Ireland; Conway Institute of Biomolecular & Biomedical Research, University College Dublin, Belfield, Dublin 4, D04 V1W8, Ireland. Electronic address:

Cell dissemination during tumor development is a characteristic of cancer metastasis. Dissemination from three-dimensional spheroid models on extracellular matrices designed to mimic tissue-specific physiological microenvironments may allow us to better elucidate the mechanism behind cancer metastasis and the response to therapeutic agents. The orientation of fibrillar collagen plays a key role in cellular processes and mediates metastasis through contact-guidance. Read More

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Effect of Ce substitution on the local magnetic ordering and phonon instabilities in antiferromagnetic DyCrOperovskites.

J Phys Condens Matter 2022 May 18. Epub 2022 May 18.

Physics, Indian Institute of Technology Guwahati, Professor, Department of Physics IIT Guwahati, IIT Guwahati, Guwahati, Assam, 781039, INDIA.

A detailed crystal structure analysis, temperature and field dependence of magnetic characteristics and phonon instabilities for different compositions (0.1 ≤ x ≤ 0.5) of DyCeCrOsolid-solutions have been reported. Read More

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Protonated cross-linkable nanocomposite coatings with outstanding underwater superoleophobic and anti-viscous oil-fouling properties for crude oil/water separation.

J Hazard Mater 2022 May 11;436:129129. Epub 2022 May 11.

The First Affiliated Hospital (Shenzhen People's Hospital), Southern University of Science and Technology, Shenzhen 518055, China. Electronic address:

Superhydrophilic/underwater superoleophobic coatings that effectively prevent viscous oil contamination have been of considerable interest for the great potential in oil spill remediation and oilfield wastewater treatment. In the present work, a protonated cross-linkable nanocomposite coating with robust underwater superoleophobicity and intensified hydration capability is proposed through the synthesis of active polymeric nanocomplex (PNC), cross-linking reaction between PNC and hydrophilic chitosan (CS), and final protonation to further improve water affinity. Benefiting from the hierarchical structure and strong hydration capability induced by electrostatic interactions and hydrogen bondings, the nanocomposite coating coated textile exhibits excellent superhydrophilicity (within 0. Read More

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