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Perforating folliculitis, angioedema, hand-foot syndrome--multiple cutaneous side effects in a patient treated with sorafenib.

J Dtsch Dermatol Ges 2009 May 29;7(5):449-52. Epub 2009 Jan 29.

Donauspital SMZ Ost, Department of Dermatology and Venereology, Vienna, Austria.

A patient with clear cell renal cell carcinoma was treated with sorafenib, a multikinase inhibitor, which induced a variety of cutaneous side effects. In addition to xerosis, he developed angioedema (AE), hand-foot syndrome (HFS) and perforating folliculitis (PF). The latter three occurred in a dose-dependent manner. Read More

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