Clin Nucl Med 2021 Mar 16. Epub 2021 Mar 16.
From the Division of Hematology/Oncology, Department of Pediatrics, School of Medicine Hematology Research Center, Amir Oncology Hospital, Shiraz University of Medical Sciences, Shiraz The Persian Gulf Nuclear Medicine Research Center, Department of Molecular Imaging and Radionuclide Therapy, Bushehr Medical University Hospital, Bushehr University of Medical Sciences, Bushehr Cancer Research Center, Razavi Hospital, Imam Reza International University, Mashhad Hematology Research Center, Shiraz University of Medical Sciences, Shiraz Department of Pediatric Hematology and Oncology, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Department of Diagnostic Imaging, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada Department of Nuclear Medicine, Klinikum Westfalen, Dortmund, Germany.
Background: Recent evidence has demonstrated high expression of somatostatin receptors in neuroblastoma (NB) cells. Because of this, we endeavored to evaluate the diagnostic performance and clinical efficacy of 68Ga-DOTATATE PET/CT and peptide receptor radionuclide therapy (PRRT) using 177Lu-DOTATATE combined with chemotherapy in pediatric NB patients.
Patients And Methods: In total, 14 pediatric patients with histopathologically confirmed NB underwent 68Ga-DOTATATE PET/CT. Read More