17,145 results match your criteria anatomic area

Surgical Outcomes of Inguinal-, Pubic-, and Adductor-Related Chronic Pain in Athletes: A Systematic Review Based on Surgical Technique.

Orthop J Sports Med 2021 Sep 13;9(9):23259671211023116. Epub 2021 Sep 13.

New York Hip Preservation and Groin Center at Lenox Hill Hospital of Northwell Health, New York, New York, USA.

Background: Controversies remain regarding the surgical treatment of inguinal-, pubic-, and adductor-related chronic groin pain (CGP) in athletes.

Purpose: To investigate the outcomes of surgery for CGP in athletes based on surgical technique and anatomic area addressed.

Study Design: Systematic review; Level of evidence, 4. Read More

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September 2021

Diverse midbrain dopaminergic neuron subtypes and implications for complex clinical symptoms of Parkinson's disease.

Ageing Neurodegener Dis 2021 15;1(4). Epub 2021 Jul 15.

Transgenic Section, Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD 20892, USA.

Parkinson's disease (PD), the most common degenerative movement disorder, is clinically manifested with various motor and non-motor symptoms. Degeneration of midbrain (SNc) dopaminergic neurons (DANs) is generally attributed to the motor syndrome. The underlying neuronal mechanisms of non-motor syndrome are largely unexplored. Read More

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Mismatch Repair Protein Expressions in Cohort of Colorectal Carcinoma Patients in Lagos.

Niger J Clin Pract 2021 Sep;24(9):1294-1299

Department of Anatomic and Molecular Pathology, College of Medicine, University of Lagos and Lagos University Teaching Hospital, Idi-Araba, Lagos, Nigeria.

Background: Colorectal carcinoma (CRC) is a major cause of morbidity and mortality worldwide. Microsatellite instability pathway is important in the pathogenesis of CRC. Immunohistochemistry expression of mismatch repair (MMR) proteins serves as surrogate marker for MMR gene mutation. Read More

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September 2021

Does Bone Regrow After Notchplasty in ACL Reconstruction? A Prospective Computed Tomography Study With 2-Year Follow-up.

Orthop J Sports Med 2021 Sep 8;9(9):23259671211029228. Epub 2021 Sep 8.

1st Orthopaedic Department, 424 Army General Training Hospital, Thessaloniki, Greece.

Background: During notchplasty in anterior cruciate ligament (ACL) reconstruction, bone is excised from the lateral and roof area of the notch to widen the intercondylar space and avoid notch-graft impingement in extension. There are concerns that bone regrowth of the area will cause narrowing and increase the risk of complications.

Purpose: To determine the possibility of late narrowing of the notch after notchplasty using computed tomography (CT) analysis. Read More

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September 2021

Abdominal aortic aneurysm model in swine with bovine pericardium patch.

J Vasc Bras 2021 1;20:e20210080. Epub 2021 Sep 1.

Universidade Federal do Rio Grande do Sul - UFRGS, Porto Alegre, RS, Brasil.

Background: Aneurysm repair using endovascular techniques has grown in importance as materials have improved. Studies of endovascular prostheses require experimental models that reproduce anatomic and pathophysiological characteristics of human aneurysms.

Objectives: To describe a porcine model of abdominal aortic aneurysm. Read More

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September 2021

Life-Threatening Sublingual Hematoma after Mandibular Implant Placement - A Case Report.

Ann Maxillofac Surg 2021 Jan-Jun;11(1):169-172. Epub 2021 Mar 24.

Servicio de Cirugía Oral y Maxilofacial. Hospital General de Castellón, Avenida de Benicassim, Castellón, Spain.

Rationale: Sublingual hematoma is a potentially lethal complication following mandibular implant placement. Due to the scarce cases reported, the management is controversial. In this article, a case is discussed focusing on the different treatment options to establish an orientative guideline. Read More

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Preliminary Computed Tomography Radiomics Model for Predicting Pretreatment CD8+ T-Cell Infiltration Status for Primary Head and Neck Squamous Cell Carcinoma.

J Comput Assist Tomogr 2021 Jul-Aug 01;45(4):629-636

Department of Radiology, The University of Chicago, Chicago, IL.

Purpose: Immunotherapy has emerged as a treatment option for head and neck squamous cell carcinoma (HNSCC), with tumor response being linked to the CD8+ T-cell inflammation. The purpose of this study is to assess whether computed tomography (CT) radiomic analysis can predict CD8+ T-cell enrichment in HNSCC primary tumors.

Methods: This retrospective study included 71 patients from a head and neck cancer genomics cohort with CD8+ T-cell enrichment status. Read More

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September 2021

Outcomes In Patients With Smaller Body Surface Area after HeartMate 3 Left Ventricular Assist Device Implantation.

Artif Organs 2021 Sep 13. Epub 2021 Sep 13.

Department of Cardiology, Advanced Heart Failure Program, Medstar Heart and Vascular Institute, USA.

Background: Due to anatomic and physiologic concerns, prior generations of the left ventricular assist devices (LVAD) have frequently been denied to patients with small body size. However, outcomes in patients with small body surface area (BSA) following HeartMate 3 (HM3) LVAD implantation remain relatively unknown.

Methods: A cohort of 220 patients implanted at a single center was divided into 2 groups: BSA ≤1. Read More

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September 2021

Types, characteristics and anatomic location of physical signs in elder abuse: a systematic review : Awareness and recognition of injury patterns.

Eur Geriatr Med 2021 Sep 13. Epub 2021 Sep 13.

Research Department of Emergency and Critical Care, Knowledge Centre of Sustainable Healthcare, School of Health Studies, HAN University of Applied Sciences, PO Box 6960, 6503 GL, Nijmegen, The Netherlands.

Purpose: Elder abuse is a worldwide problem with serious consequences for individuals and society. The recognition of elder abuse is complex due to a lack of awareness and knowledge. In this systematic review, types, characteristics and anatomic location of physical signs in elder abuse were identified. Read More

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September 2021

Weakly supervised anomaly segmentation in retinal OCT images using an adversarial learning approach.

Biomed Opt Express 2021 Aug 7;12(8):4713-4729. Epub 2021 Jul 7.

School of Biomedical Engineering (Suzhou), Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230026, China.

Lesion detection is a critical component of disease diagnosis, but the manual segmentation of lesions in medical images is time-consuming and experience-demanding. These issues have recently been addressed through deep learning models. However, most of the existing algorithms were developed using supervised training, which requires time-intensive manual labeling and prevents the model from detecting unaware lesions. Read More

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G-spot: Fact or Fiction?: A Systematic Review.

Sex Med 2021 Sep 9;9(5):100435. Epub 2021 Sep 9.

Department of Obstetrics and Gynecology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.

Introduction: The G-spot, a putative erogenous area in the anterior vaginal wall, is a widely accepted concept in the mainstream media, but controversial in medical literature.

Aim: Review of the scientific data concerning the existence, location, and size of the G-spot.

Methods: Search on Pubmed, Pubmed Central, Cochrane, clinicaltrials. Read More

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September 2021

Feasibility and Accuracy of Automated Three-Dimensional Echocardiographic Analysis of Left Atrial Appendage for Transcatheter Closure.

J Am Soc Echocardiogr 2021 Sep 8. Epub 2021 Sep 8.

2Ai - School of Technology, IPCA, Barcelos, Portugal.

Background: Procedural success of transcatheter left atrial appendage closure (LAAC) is dependent on correct device selection. Three-dimensional transesophageal echocardiography (3D-TEE) is more accurate than the two-dimensional (2D) modality for evaluation of the complex anatomy of LAA. However, 3D-TEE analysis of LAA is challenging and highly expertise dependent. Read More

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September 2021

Subtyping Schizophrenia Patients Based on Patterns of Structural Brain Alterations.

Schizophr Bull 2021 Sep 11. Epub 2021 Sep 11.

Huaxi MR Research Center (HMRRC), Department of Radiology, West China Hospital of Sichuan University, Chengdu, Sichuan, China.

Schizophrenia is a complex and heterogeneous syndrome. Whether quantitative imaging biomarkers can identify discrete subgroups of patients as might be used to foster personalized medicine approaches for patient care remains unclear. Cross-sectional structural MR images of 163 never-treated first-episode schizophrenia patients (FES) and 133 chronically ill patients with midcourse schizophrenia from the Bipolar and Schizophrenia Network for Intermediate Phenotypes (B-SNIP) consortium and a total of 403 healthy controls were recruited. Read More

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September 2021

Glomerular Disease Classification and Lesion Identification by Machine Learning.

Biomed J 2021 Sep 7. Epub 2021 Sep 7.

Department of Anatomic Pathology, Chang Gung Memorial Hospital Linkou Main Branch, No. 5, Fuxing St., Guishan Dist., Taoyuan City 333, Taiwan. Electronic address:

Background: Classification of glomerular diseases and identification of glomerular lesions require careful morphological examination by experienced nephropathologists, which is labor-intensive, time-consuming, and prone to interobserver variability. In this regard, recent advance in machine learning-based image analysis is promising.

Methods: We combined Mask Region-based Convolutional Neural Networks (Mask R-CNN) with an additional classification step to build a glomerulus detection model using human kidney biopsy samples. Read More

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September 2021

Sex Specific Criteria for Repair Should be Utilized in Patients Undergoing Aortic Aneurysm Repair.

J Vasc Surg 2021 Sep 7. Epub 2021 Sep 7.

The Divisions of Vascular and Endovascular Surgery, Beth Israel Deaconess Medical Center, Boston, MA. Electronic address:

Objective: Female patients are more likely to undergo repair of intact and ruptured abdominal aortic aneurysm (AAA) at smaller aortic diameter compared with male patients. By adjusting for inherent anatomic differences between sexes, aortic size index (ASI) and aortic height index (AHI) may provide an additional method for guiding treatment. We therefore analyzed sex-specific criteria for AAA repair using aortic diameter, ASI, and AHI. Read More

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September 2021

Melanoma of the Hands and Feet (With Reconstruction).

Clin Plast Surg 2021 Oct 27;48(4):687-698. Epub 2021 Jun 27.

Division of Plastic Surgery, Southern Illinois University School of Medicine, 747 N Rutledge Street #3, Springfield, IL 62702, USA.

Melanomas only account for 4% of all dermatologic cancers yet are responsible for 80% of deaths. Notably, melanomas of the hand and foot have a worse prognosis when compared with melanomas of other anatomic regions. Likely this is due to intrinsic biologic characteristics, delayed diagnosis, difficult surgical excision due to delicate anatomy, and lack of definitive diagnostic and therapeutic guidelines. Read More

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October 2021

The Importance of Route Anatomic Variants of the Common Hepatic Artery.

Chirurgia (Bucur) 2021 Aug;116(4):466-472

Variants of vascularization in the celiac and upper mesenteric artery are described in the dedicated literature. The anatomy of this area is a subject of interest, considering the potential techniques and the risk of generating intraoperative incidents/accidents or complications. Material and method: We have conducted a unicentric retrospective study, in the Surgery Clinic No. Read More

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Fractional Lengthening of the Forearm Flexor Muscles: Anatomic Study.

J Hand Surg Am 2021 Sep 3. Epub 2021 Sep 3.

Institut de la Main, Clinique Bizet, Paris France. Electronic address:

Purpose: Forearm muscles can undergo contracture for a number of reasons, including spasticity. This deformity is amenable to surgical treatment in select cases. Among the different techniques available, fractional lengthening of the forearm flexor muscles involves multiple tenotomies at the musculotendinous junction. Read More

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September 2021

Fracture fixation in extremity trauma with carbon fiber-reinforced polyetheretherketone (CFR-PEEK) plates: evidence today.

Eur J Trauma Emerg Surg 2021 Sep 6. Epub 2021 Sep 6.

Academic Department of Trauma and Orthopaedic Surgery, School of Medicine, University of Leeds, Leeds, UK.

Purpose: To compare the CFR-PEEK plates with conventional plates in fracture fixation with regards to clinical and radiological outcomes and complications.

Methods: A systematic literature search was conducted in four online databases independently by two reviewers using the Cochrane methodology for systematic reviews. The identified relevant studies were assessed against predetermined inclusion/exclusion criteria. Read More

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September 2021

Multiparametric magnetic resonance imaging/magnetic resonance elastography assesses progression and regression of steatosis, inflammation, and fibrosis in alcohol-associated liver disease.

Alcohol Clin Exp Res 2021 Sep 5. Epub 2021 Sep 5.

Radiology, Mayo Clinic, Rochester, Minnesota, USA.

Background: Magnetic resonance imaging (MRI) and MRI-based elastography (MRE) are the most promising noninvasive techniques in assessing liver diseases. The purpose of this study was to evaluate an advanced multiparametric imaging method for staging disease and assessing treatment response in realistic preclinical ALD models.

Methods: We utilized four different preclinical mouse models in our study: Model 1-mice were fed a fast-food diet and fructose water for 48 weeks to induce nonalcoholic fatty liver disease; Model 2-mice were fed chronic-binge ethanol (EtOH) for 10 days or 8 weeks to induce liver steatosis/inflammation. Read More

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September 2021

p53, p16 and ki67 as immunohistochemical prognostic markers in uterine smooth muscle tumors of uncertain malignant potential (STUMP).

Pathol Res Pract 2021 Aug 25;226:153592. Epub 2021 Aug 25.

Anatomic Pathology Unit, Department of Advanced Biomedical Sciences, School of Medicine, University of Naples Federico II, Naples, Italy; Ospedale Maggiore Policlinico Milano, Milan, Italy.

The risk stratification in gynecologic smooth muscle tumors of uncertain malignant potential (STUMP) is a crucial issue, but at present there are no validated prognostic markers. We aimed to assess p53, p16 and ki67 as immunohistochemical prognostic markers in STUMP through a systematic review and meta-analysis. Electronic databases were searched from their inception to July 2020. Read More

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Immune microenvironment composition in high-grade serous ovarian cancers based on BRCA mutational status.

J Cancer Res Clin Oncol 2021 Sep 2. Epub 2021 Sep 2.

Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX, 77054, USA.

Purpose: An in-depth analysis of the tumor microenvironment of ovarian cancer is needed. The purpose of this study was to elucidate the architecture of the immune microenvironment of high-grade serous ovarian cancers (HGSCs) with or without BRCA1 and BRCA2 mutations.

Methods: A cohort of highly annotated HGSC patients with known germline BRCA1 and BRCA2 status was selected, and pretreatment tumor tissue specimens were analyzed with a multiplexed staining technique aimed at detecting lymphocytes, macrophages, and fibroblasts in the whole tumor area and in specific regions including epithelium, stroma, and perivascular areas. Read More

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September 2021

Primary Perivascular Epithelioid Cell Tumor (PEComa) of the Ovary: A Case Report and Review of the Literature.

Anticancer Res 2021 Sep;41(9):4483-4488

Department of Translational Research and New Surgical and Medical Technologies, Division of General and Transplant Surgery, University of Pisa, Pisa, Italy.

Background: Perivascular epithelioid cell tumors (PEComa)s are mesenchymal neoplasms located at various anatomic sites, which usually express both melanocytic and myogenic markers.

Case Report: A 60-year-old woman underwent laparotomy for a huge, heterogeneous, right ovarian mass. The histological examination of the surgical specimen revealed a neoplasm consisting of both cells with clear or eosinophilic cytoplasm and spindle cells in a myxoid stroma. Read More

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September 2021

Electrocardiographic characteristics and ablation of ventricular arrhythmias originating from the basal inferoseptal area.

Europace 2021 Sep 2. Epub 2021 Sep 2.

Department of Medicine, Division of Cardiology, Pauley Heart Center, Virginia Commonwealth University, Gateway Bldg, 3rd Floor, 3-216, 1200 East Marshall St, Richmond, VA 23298, USA.

Aims : Ventricular arrhythmias (VAs) from the basal inferoseptal (BIS) area are rare and can pose unique challenges during catheter ablation (CA) due to the anatomic complexity. The study sought to describe the electrocardiographic and clinical characteristics of VAs originating from the BIS area.

Methods And Results : Patients with VAs and successful ablation at the BIS area from 2016 to 2020 were included. Read More

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September 2021

Rare Portal Venous Anomaly in a Living Liver Donor: A Case Report.

Transplant Proc 2021 Aug 29. Epub 2021 Aug 29.

Department of Hepato-Biliary-Pancreatic and Breast Surgery, Ehime University Graduate School of Medicine, Ehime, Japan.

Knowledge of the anatomy of the portal system is essential for safe liver resection. We report a very rare anatomic anomaly of the portal system in a living liver donor. A 24-year-old female living liver donor was found to have anomalies of the portal system on preoperative contrast-enhanced computed tomography. Read More

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Root canal morphology and variations in mandibular second molars: an in vivo cone-beam computed tomography analysis.

BMC Oral Health 2021 Sep 1;21(1):424. Epub 2021 Sep 1.

Postgraduate Department of Endodontics, Universidad Central de Venezuela, Caracas, Venezuela.

Background: The purpose of this study was to determine the anatomical variations of the root canal system of mandibular second molars using cone-beam computed tomography (CBCT).

Methods: 190 mandibular second molars cone-beam computed tomography images were reviewed. The evaluation was performed by a radiologist with endodontic experience and two endodontists trained with CBCT technology. Read More

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September 2021

Quantitative Anatomic Comparison of Microsurgical Transcranial, Endoscopic Endonasal, and Transorbital Approaches to the Spheno-Orbital Region.

Oper Neurosurg (Hagerstown) 2021 Sep 1. Epub 2021 Sep 1.

Division of Neurosurgery, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Brescia, Italy.

Background: The spheno-orbital region (SOR) is a complex anatomic area that can be accessed with different surgical approaches.

Objective: To quantitatively compare, in a preclinical setting, microsurgical transcranial approaches (MTAs), endoscopic endonasal transpterygoid approach (EEA), and endoscopic transorbital approaches (ETOAs) to the SOR.

Methods: These approaches were performed in 5 specimens: EEA, ETOAs (superior eyelid and inferolateral), anterolateral MTAs (supraorbital, minipterional, pterional, pterional-transzygomatic, and frontotemporal-orbitozygomatic), and lateral MTAs (subtemporal and subtemporal transzygomatic). Read More

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September 2021

Significance of the Hepatic Falciform Artery.

Cureus 2021 Jul 17;13(7):e16440. Epub 2021 Jul 17.

Emergency Medicine, Envision Physician Services, Plantation, USA.

The authors present a case that highlights the anatomy of the hepatic falciform artery and describes its importance. The hepatic falciform artery is an anatomic variant that arises from the hepatic vasculature and provides arterial communication between the abdominal wall and the liver. It is essential to identify its presence, especially when surgery or embolization is planned for that area. Read More

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Conferred with a new life: A case report of management of a severe midface trauma and subsequent oral rehabilitation.

Clin Case Rep 2021 Aug 25;9(8):e04620. Epub 2021 Aug 25.

Department of Oral and Maxillofacial Surgery School of Dentistry Shahid Beheshti University of Medical Sciences Tehran Iran.

Maxillofacial traumas have been associated with 14%-17% of all facial injuries. The most common etiology of mid-facial traumas is motor vehicle accidents followed by interpersonal assaults. The devastating nature of maxillofacial defects makes reconstruction of the midface challenging, due to multiple required surgeries and extensive rehabilitation phase. Read More

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Evaluating the potential utility of three-dimensional printed models in preoperative planning and patient consent in gastrointestinal cancer surgery.

Ann R Coll Surg Engl 2021 Sep;103(8):615-620

The Christie NHS Foundation Trust, Manchester, UK.

Introduction: The report from the Royal College of Surgeons of England acknowledges the important role that three-dimensional imaging will play in support of personalised surgical interventions. One component of this is preoperative planning. We investigated surgeons' and patients' perceptions of this evolving technology. Read More

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September 2021