Cellulose (Lond) 2021 Jul 17:1-11. Epub 2021 Jul 17.
Department of Chemical Engineering, University of New Brunswick, Fredericton, NB E3B 5A3 Canada.
Lateral flow assay (LFA) is an important point-of-care (POC) test platform due to the associated portability, on-site testing, and low cost for diagnosis of pathogen infections and disease biomarkers. However, compared to high-end analyzers in hospitals, LFA devices, in particular, paper- based LFA tests, fall short in accuracy. This study focuses on two ways to improve LFAs: (1) using cellulose fibers, rather than glass fibers for a sample pad, and (2) incorporating a one-step simple, facile, and low cost PVA dam into the LFA. Read More