Appl Immunohistochem Mol Morphol 2021 Feb 9. Epub 2021 Feb 9.
Postgraduate Program in Dentistry Department of Pathology, Health Sciences Center, Federal University of Santa Catarina, Florianópolis, Santa Catarina Postgraduate Program in Business, Federal University of Paraná, Curitiba, Paraná, Brazil.
The aim of this study was to investigate the immunoexpression of matrix metalloproteinase 9 (MMP-9), tissue inhibitor of metalloproteinase 1 (TIMP-1), and vimentin (VIM) and its association with the inflammatory reaction (IR) and clinical parameters in oral epithelial dysplasia (ED). The sample was composed of 66 cases of ED, 27 oral squamous cell carcinoma (OSCC), and 28 non-neoplastic epithelium (NNE). ED was graded according to the binary system as low-risk ED (n=42) and high-risk epithelial dysplasia (HRED: n=24). Read More