140 results match your criteria analyze nanofiber


Doxycycline-doped membranes induced osteogenic gene expression on osteoblastic cells.

J Dent 2021 Apr 20;109:103676. Epub 2021 Apr 20.

Instituto Investigación Biosanitaria, ibs, Granada, Granada, Spain; Biomedical Group (BIO277), Department of Nursing, Faculty of Health Sciences, University of Granada, Spain; Institute of Neuroscience, University of Granada, Centro de Investigación Biomédica (CIBM), Parque de Tecnológico de la Salud (PTS), Granada, Spain.

Objectives: To analyze how novel developed silicon dioxide composite membranes, functionalized with zinc or doxycycline, can modulate the expression of genes related to the osteogenic functional capacity of osteoblastic cells.

Methods: The composite nanofibers membranes were manufactured by using a novel polymeric blend and 20 nm silicon dioxide nanoparticles (SiO-NPs). To manufacture the membranes, 20 nm SiO-NPs were added to the polymer solution and the resulting suspension was processed by electrospinning. Read More

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Disassembly of TEMPO-Oxidized Cellulose Fibers: Intersheet and Interchain Interactions in the Isolation of Nanofibers and Unitary Chains.

J Phys Chem B 2021 04 6;125(14):3717-3724. Epub 2021 Apr 6.

Brazilian Nanotechnology National Laboratory (LNNano), Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, São Paulo 13083-970, Brazil.

Cellulose disassembly is an important issue in designing nanostructures using cellulose-based materials. In this work, we present a combination of experimental and theoretical study addressing the disassembly of cellulose nanofibrils. Through 2,2,6,6-tetramethylpiperidine-1-oxyl-mediated oxidation processes, combined with atomic force microscopy results, we show the formation of nanofibers with diameters corresponding to that of a single-cellulose polymer chain. Read More

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Tissue Engineering for the Insertions of Tendons and Ligaments: An Overview of Electrospun Biomaterials and Structures.

Front Bioeng Biotechnol 2021 2;9:645544. Epub 2021 Mar 2.

Department of Industrial Engineering, Alma Mater Studiorum-Università di Bologna, Bologna, Italy.

The musculoskeletal system is composed by hard and soft tissue. These tissues are characterized by a wide range of mechanical properties that cause a progressive transition from one to the other. These material gradients are mandatory to reduce stress concentrations at the junction site. Read More

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Synthesis of Highly Conductive Electrospun Recycled Polyethylene Terephthalate Nanofibers Using the Electroless Deposition Method.

Nanomaterials (Basel) 2021 Feb 19;11(2). Epub 2021 Feb 19.

Nano Fusion Technology Research Group, Division of Frontier Fibers, Institute for Fiber Engineering (IFES), Interdisciplinary Cluster for Cutting Edge Research (ICCER), Shinshu University, Tokida 3-15-1, Ueda, Nagano Prefecture 386-8567, Japan.

Plastic bottles are generally recycled by remolding them into numerous products. In this study, waste from plastic bottles was used to fabricate recycled polyethylene terephthalate (r-PET) nanofibers via the electrospinning technique, and high-performance conductive polyethylene terephthalate nanofibers (r-PET nanofibers) were prepared followed by copper deposition using the electroless deposition (ELD) method. Firstly, the electrospun r-PET nanofibers were chemically modified with silane molecules and polymerized with 2-(methacryloyloxy) ethyl trimethylammonium chloride (METAC) solution. Read More

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February 2021

Construction of Nanocrystalline Cellulose-Based Composite Fiber Films with Excellent Porosity Performances via an Electrospinning Strategy.

ACS Omega 2021 Feb 11;6(7):4958-4967. Epub 2021 Feb 11.

State Key Laboratory of Metastable Materials Science and Technology, Yanshan University, Qinhuangdao 066004, P. R. China.

Cellulose nanocrystals (CNCs) not only have environmental protection characteristics of being lightweight, degradable, green, and renewable but also have some nanocharacteristics of high strength, large specific surface area, and obvious small size effect, so they are often used as a reinforcing agent in various polymers. However, the hydrogen bonding between CNC molecules is relatively strong, and they can easily aggregate and get entangled with each other. In this work, several large-porosity composite nanofiber films, KH550-CNC/waterborne polyurethane (WPU)/poly(vinyl alcohol) (PVAL) with KH550-modified CNCs, are prepared using poly(vinyl alcohol) (PVAL) solution and electrospinning technology. Read More

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February 2021

Electrospun nanofiber scaffolds for the propagation and analysis of breast cancer stem cells in vitro.

Biomed Mater 2021 Feb 26;16(3):035004. Epub 2021 Feb 26.

National Institute of Molecular Biology and Biotechnology, College of Science, National Science Complex, University of the Philippines, Diliman, Quezon City 1101, Philippines.

Despite advances in cancer treatment, breast cancer remains the second foremost cause of cancer mortality among women, with a high rate of relapse after initial treatment success. A subpopulation of highly malignant cancer cells, known as cancer stem cells (CSCs), is suspected to be linked to metastasis and relapse. Targeting of CSCs may therefore provide a means of addressing cancer-related mortality. Read More

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February 2021

Preparation of Polyacrylonitrile/Ni-MOF electrospun nanofiber as an efficient fiber coating material for headspace solid-phase microextraction of diazinon and chlorpyrifos followed by CD-IMS analysis.

Food Chem 2021 Jul 9;350:129242. Epub 2021 Feb 9.

Department of Analytical Chemistry and Pollutants, Faculty of Chemistry and Petroleum Sciences, Shahid Beheshti University, Tehran, Iran.

Herein, an electrospun polyacrylonitrile/nickel-based metal-organic framework nanocomposite (PAN/Ni-MOF) coating on a stainless steel wire was synthesized and employed as a novel nanosorbent for headspace solid-phase microextraction (HS-SPME) of organophosphorus pesticides (OPPs), diazinon (DIZ), and chlorpyrifos (CPS) from the diverse aqueous media followed by corona discharge ion mobility spectrometry (CD-IMS). Under the optimum experimental conditions, the calibration plots were linear in the range of 1.0-250. Read More

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State of the Art and New Directions on Electrospun Lignin/Cellulose Nanofibers for Supercapacitor Application: A Systematic Literature Review.

Polymers (Basel) 2020 Dec 1;12(12). Epub 2020 Dec 1.

Department of Physics, Al-Qalam University Katsina, Katsina 820252, Nigeria.

Supercapacitors are energy storage devices with high power density, rapid charge/discharge rate, and excellent cycle stability. Carbon-based supercapacitors are increasingly attracting attention because of their large surface area and high porosity. Carbon-based materials research has been recently centered on biomass-based materials due to the rising need to maintain a sustainable environment. Read More

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December 2020

La(OH) nano-rods/polyacrylonitrile nanofibers: fabrication, characterization and application for phosphate removal.

Water Sci Technol 2020 Nov;82(10):2098-2113

School of Civil Engineering, Chang'an University, Xi'an, 710061, China E-mail:

In this study, an excellent phosphate adsorbent was prepared for removing phosphate to an extremely low concentration. The La(OH) nano-rods stabilizing in polyacrylonitrile (PAN) nanofibers (PLNFs) were prepared by electrospinning and a subsequent in situ precipitation. PAN nanofibers were employed as the matrix of the composite nanofibers, where the well-dispersed La(OH) nano-rods were encapsulated as the active species for highly efficient phosphate capture owing to the strong binding between phosphate and lanthanum. Read More

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November 2020

Assembly of Pt Nanoparticles on Graphitized Carbon Nanofibers as Hierarchically Structured Electrodes.

ACS Appl Nano Mater 2020 Oct 1;3(10):9880-9888. Epub 2020 Sep 1.

NEST, Istituto Nanoscienze-CNR, Piazza S. Silvestro 12, I-56127 Pisa, Italy.

Carbon-based nanofibers decorated with metallic nanoparticles (NPs) as hierarchically structured electrodes offer significant opportunities for use in low-temperature fuel cells, electrolyzers, flow and air batteries, and electrochemical sensors. We present a facile and scalable method for preparing nanostructured electrodes composed of Pt NPs on graphitized carbon nanofibers. Electrospinning directly addresses the issues related to large-scale production of Pt-based fuel cell electrocatalysts. Read More

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October 2020

Electrospun nanofiber scaffolds for the propagation and analysis of breast cancer stem cells.

Biomed Mater 2020 Oct 22. Epub 2020 Oct 22.

Mining, Metallurgical, and Materials Engineering, College of Engineering, University of the Philippines Diliman, Quezon City, 1101, PHILIPPINES.

Despite advances in cancer treatment, breast cancer remains the second foremost cause of cancer mortality among women, with a high rate of relapse after initial treatment success. A subpopulation of highly malignant cancer cells, known as cancer stem cells (CSCs), is suspected to be linked to metastasis and relapse. Targeting of CSCs may therefore provide a means of addressing cancer-related mortality. Read More

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October 2020

Nanomaterials in Dentistry: State of the Art and Future Challenges.

Nanomaterials (Basel) 2020 Sep 7;10(9). Epub 2020 Sep 7.

Departamento de Ingeniería Química, Universidad de Málaga, E-29071 Málaga, Spain.

Nanomaterials are commonly considered as those materials in which the shape and molecular composition at a nanometer scale can be controlled. Subsequently, they present extraordinary properties that are being useful for the development of new and improved applications in many fields, including medicine. In dentistry, several research efforts are being conducted, especially during the last decade, for the improvement of the properties of materials used in dentistry. Read More

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September 2020

Control of seed formation allows two distinct self-sorting patterns of supramolecular nanofibers.

Nat Commun 2020 08 14;11(1):4100. Epub 2020 Aug 14.

Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto, 615-8510, Japan.

Self-sorting double network hydrogels comprising orthogonal supramolecular nanofibers have attracted attention as artificially-regulated multi-component systems. Regulation of network patterns of self-sorted nanofibers is considered as a key for potential applications such as optoelectronics, but still challenging owing to a lack of useful methods to prepare and analyze the network patterns. Herein, we describe the selective construction of two distinct self-sorting network patterns, interpenetrated and parallel, by controlling the kinetics of seed formation with dynamic covalent oxime chemistry. Read More

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Morphological transformation enhances Tumor Retention by Regulating the Self-assembly of Doxorubicin-peptide Conjugates.

Theranostics 2020 9;10(18):8162-8178. Epub 2020 Jul 9.

College of pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China.

Both spatial accuracy and temporal persistence are crucial in drug delivery, especially for anti-tumor intravenous nanomedicines, which have limited persistence due to their small particle sizes and easy removal from tumors. The present study takes advantage of morphological transformation strategy to regulate intravenous nanomedicines to display different sizes in different areas, achieving high efficient enrichment and long retention in lesions. We designed and synthesized functional doxorubicin-peptide conjugate nanoparticles (FDPC-NPs) consisting of self-assembled doxorubicin-peptide conjugates (DPCs) and an acidic-responsive shielding layer named the functional polylysine graft (FPG), which can regulate the assembly morphology of the DPCs from spherical DPC nanoparticles (DPC-NPs) to DPC-nanofibers (DPC-NFs) by preventing the assembly force from π-π stacking and hydrogen bond between the DPC-NPs. Read More

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Simple centrifugal fractionation to reduce the size distribution of cellulose nanofibers.

Sci Rep 2020 07 16;10(1):11744. Epub 2020 Jul 16.

Center for Nanocellulose Future Composites, Department of Mechanical Engineering, Inha University, 100 Inha-Ro, Michuhol-Ku, Incheon, 22212, Korea.

Since cellulose nanofiber (CNF) has unique characteristics in terms of renewability, high specific elastic modulus and strength and transparency, it is attractive for a building block of future materials. CNF can be extracted from various natural resource by several means. However, the size of the extracted CNF is very broad and uniformity of the extracted CNF is very important for many applications. Read More

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Development of fibrous PLGA/fibrin scaffolds as a potential skin substitute.

Biomed Mater 2020 07 27;15(5):055014. Epub 2020 Jul 27.

Hematology and Stem Cell Laboratory, Faculty of Pharmacy, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS 90610-000, Brazil. Post Graduate Program in Physiology, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS 90050-170, Brazil. Author to whom any correspondence should be addressed.

The aim of this study has been to fabricate a hybrid electrospun nanofibrous scaffold composed of poly(lactic-co-glycolic) acid (PLGA)/fibrin polymers to be used as a skin substitute and analyze its physical and biological properties. Fibrin was obtained from rat blood plasma, characterized and solubilized in formic acid. The final electrospinning solution concentration was 40% PLGA (w/v) and 1% fibrin (w/v). Read More

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Use of aloin-based and rosin-based electrospun nanofibers as natural nanosorbents for the extraction of polycyclic aromatic hydrocarbons and phenoxyacetic acid herbicides by microextraction in packed syringe method prior to GC-FID detection.

Mikrochim Acta 2020 06 22;187(7):401. Epub 2020 Jun 22.

Department of Chemistry and Pollutants, Shahid Beheshti University, G.C., Evin, P.O. Box 1983969411, Tehran, Iran.

The synthesis of three kinds of sorbents is described. The first kind was a hydrophobic nanofiber as a specific sorbent for non-polar compounds. The second one was a hydrophilic nanofiber as a specific sorbent for polar compounds and the third one was a generic sorbent synthesized from hydrophilic and hydrophobic compounds. Read More

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Electrospun Resveratrol-Loaded Polyvinylpyrrolidone/Cyclodextrin Nanofibers and Their Biomedical Applications.

Pharmaceutics 2020 Jun 13;12(6). Epub 2020 Jun 13.

Department of Fragrance and Cosmetic Science, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 807, Taiwan.

Resveratrol is a naturally occurring polyphenol compound which has been shown to possess antioxidant and anti-inflammatory properties. However, its pharmaceutical applications are limited by its poor water solubility. In this study, we used electrospinning technology to synthesize nanofibers of polyvinylpyrrolidone (PVP) and hydroxypropyl-β-cyclodextrin (HPBCD) loaded with resveratrol. Read More

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Co-Culturing of Endothelial and Cancer Cells in a Nanofibrous Scaffold-Based Two-Layer System.

Int J Mol Sci 2020 Jun 10;21(11). Epub 2020 Jun 10.

Department of Pharmacology, School of Medicine, Ajou University, Suwon 16499, Korea.

Angiogenesis is critical for local tumor growth. This study aimed to develop a three-dimensional two-layer co-culture system to investigate effects of cancer cells on the growth of endothelial cells (ECs). Poly(ε-caprolactone) (PCL) nanofibrous membranes were generated via electrospinning of PCL in chloroform (C-PCL-M) and chloroform and dimethylformamide (C/DMF-PCL-M). Read More

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Solution Blow Spinning of Polyvinylidene Fluoride Based Fibers for Energy Harvesting Applications: A Review.

Polymers (Basel) 2020 Jun 7;12(6). Epub 2020 Jun 7.

Department of Mechanical and Construction Engineering, Faculty of Engineering and Environment, Northumbria University, Newcastle upon Tyne NE1 8ST, UK.

Polyvinylidene fluoride (PVDF)-based piezoelectric materials (PEMs) have found extensive applications in energy harvesting which are being extended consistently to diverse fields requiring strenuous service conditions. Hence, there is a pressing need to mass produce PVDF-based PEMs with the highest possible energy harvesting ability under a given set of conditions. To achieve high yield and efficiency, solution blow spinning (SBS) technique is attracting a lot of interest due to its operational simplicity and high throughput. Read More

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Nanomechanical Properties and Phase Behavior of Phenylalanine Amyloid Ribbon Assemblies and Amorphous Self-Healing Hydrogels.

ACS Appl Mater Interfaces 2020 May 29;12(19):21992-22001. Epub 2020 Apr 29.

ARC Training Centre in Biodevices, Faculty of Science, Engineering and Technology, Swinburne University of Technology, Melbourne, Victoria 3122, Australia.

Phenylalanine was the minimalistic and first of numerous nonproteinaceous building blocks to be demonstrated to form amyloid-like fibrils. This unexpected organization of such a simple building block into canonical architecture, which was previously observed only with proteins and peptides, has numerous implications for medicine and supramolecular chemistry. However, the morphology of phenylalanine fibrils and their mechanical properties was never characterized in solutions. Read More

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Graphene/poly (methyl methacrylate) electrochemical impedance-transduced chemiresistor for detection of volatile organic compounds in aqueous medium.

Anal Chim Acta 2020 May 3;1109:27-36. Epub 2020 Mar 3.

School of Engineering, University of British Columbia, Kelowna, BC, Canada. Electronic address:

In this paper, an impedance-transduced sensor is developed based on a nanostructured graphene (GN) and poly (methyl methacrylate) (PMMA) sensing film for the detection of individual volatile organic compounds (VOCs) in aqueous media. Benefiting from a porous and high surface area, the nanostructured nanofiber is characterized by scanning electron microscopy (SEM) and optimized by the electrochemical impedance spectroscopy (EIS) technique. The recorded EIS data indicate the selective recognition of four VOCs of interest at a constant pH while there is no redox probe. Read More

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Development of QCM based biosensor for the selective and sensitive detection of paraoxon.

Anal Biochem 2020 02 30;591:113572. Epub 2019 Dec 30.

Chemistry Department, Faculty of Science, Eskisehir Technical University, 26470, Eskisehir, Turkey. Electronic address:

In this study, a quartz crystal microbalance (QCM) based sensor was developed that selectively recognizes and binds the paraoxon molecule. For this purpose, poly (styrene-maleic anhydride) (PSMA) polymer was synthesized to obtain nanofiber. A 30% (wt/wt) PSMA/DMSO solution was prepared for use in the electrospinning process, with operating conditions of 5 kV potential and 1 mL/h flow rate. Read More

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February 2020

Electrospun Nanofibers With pH-Responsive Coatings for Control of Release Kinetics.

Front Bioeng Biotechnol 2019 27;7:309. Epub 2019 Nov 27.

Materials Science and Nano Engineering Department, Faculty of Engineering and Natural Sciences, Sabanci University, Istanbul, Turkey.

Functional and stimuli-responsive nanofibers with an enhanced surface area/volume ratio provide controlled and triggered drug release with higher efficacy. In this study, chemotherapeutic agent Rose Bengal (RB) (4,5,6,7-tetrachloro-2', 4',5',7'-tetraiodofluoresceindisodium)-loaded water-soluble polyvinyl alcohol (PVA) nanofibers were synthesized by using the electrospinning method. A thin layer of poly(4-vinylpyridine--ethylene glycol dimethacrylate) p(4VP--EGDMA) was deposited on the RB-loaded nanofibers (PVA-RB) via initiated chemical vapor deposition (iCVD), coating the fiber surfaces to provide controllable solubility and pH response to the nanofibers. Read More

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November 2019

Direct observation of multimode interference in rare-earth doped micro/nanofibers.

Opt Express 2019 Sep;27(19):26728-26737

Modal inspection of optical fibers is important for multimode application but it is challenging to collect in-situ information of propagating modes for evaluation and manipulation. Here we demonstrate direct observation of multimode interference in Er/Yb co-doped micro/nanofibers. Luminescent interference patterns are visualized by visible up-conversion of Er ions and are used for establishing the existence of higher order modes co-propagating with fundamental modes. Read More

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September 2019

A highly sensitive safrole sensor based on polyvinyl acetate (PVAc) nanofiber-coated QCM.

Sci Rep 2019 10 28;9(1):15407. Epub 2019 Oct 28.

Institute of Semiconductor Technology (IHT) and Laboratory for Emerging Nanometrology (LENA), Technische Universität Braunschweig, Braunschweig, 38106, Germany.

A novel, highly sensitive and selective safrole sensor has been developed using quartz crystal microbalance (QCM) coated with polyvinyl acetate (PVAc) nanofibers. The nanofibers were collected on the QCM sensing surface using an electrospinning method with an average diameter ranging from 612 nm to 698 nm and relatively high Q-factors (rigid coating). Scanning electron microscopy (SEM) and atomic force microscopy (AFM) were used to analyze the PVAc nanofiber surface morphology, confirming its high surface area and roughness, which are beneficial in improving the sensor sensitivity compared to its thin-film counterpart. Read More

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October 2019

Surface Mechanical Characterization of Carbon Nanofiber Reinforced Low-Density Polyethylene by Nanoindentation and Comparison with Bulk Properties.

Nanomaterials (Basel) 2019 Sep 22;9(10). Epub 2019 Sep 22.

Industrial Technology Department, College of Engineering, University of Louisiana at Lafayette, P.O. Box 43675, Lafayette, LA 70504-4130, USA.

Surface mechanical properties of low-density polyethylene (LDPE) reinforced by carbon nanofibers (CNFs) up to 3% weight load were investigated using nanoindentation (NI). Surface preparation of the nanocomposite was thoroughly investigated and atomic force microscopy (AFM) was used to analyze the surface roughness of the polished surfaces. The dispersion of nanofillers in the LDPE matrix was examined using scanning electron microscopy (SEM). Read More

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September 2019

Polypyrrole/polylactic acid nanofibrous scaffold cotransplanted with bone marrow stromal cells promotes the functional recovery of spinal cord injury in rats.

CNS Neurosci Ther 2019 09 1;25(9):951-964. Epub 2019 May 1.

Department of Functional Neurosurgery, The Third Medical Centre, Chinese PLA (People's Liberation Army) General Hospital, Beijing, China.

Aims: The objective of this study was to analyze the efficacy of polypyrrole/polylactic acid (PPy/PLA) nanofibrous scaffold cotransplanted with bone marrow stromal cells (BMSCs) in promoting the functional recovery in a rat spinal cord injury (SCI).

Methods: Female Sprague-Dawley rats were randomly divided into three groups (n = 18/group): control group, PPy/PLA group, and PPy/PLA/BMSCs group. The SCI was induced in all rats. Read More

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September 2019

Electrospun acrylonitrile butadiene styrene nanofiber film as an efficient nanosorbent for head space thin film microextraction of polycyclic aromatic hydrocarbons from water and urine samples.

Talanta 2019 Dec 22;205:120080. Epub 2019 Jun 22.

Department of Chemistry and Pollutants, Shahid Beheshti University, G.C., Evin, P.O. Box 1983969411, Tehran, Iran.

In the present study, acrylonitrile butadiene styrene (ABS) nanofiber film was fabricated on the aluminum foil via a one-step and facile electrospinning strategy. Thereafter, the fabricated film was utilized as a novel and efficient nanosorbent for headspace thin film microextraction (HS-TFME) of polycyclic aromatic hydrocarbons (PAHs). Some properties of the prepared nanofiber film like morphology, chemical structure, stability, wettability, and extraction efficiency were investigated systematically. Read More

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December 2019

Solid drug particles encapsulated bead-on-string nanofibers: the control of bead number and its corresponding release profile.

J Biomater Sci Polym Ed 2019 10 25;30(15):1454-1469. Epub 2019 Jul 25.

c College of Textile, Donghua University , Shanghai , China.

Bead-on-string nanofibers are explored as potential carriers of micro-level solid drug particles in recent years in drug release and tissue engineering. The special alternating distribution of nanoscale fiber and micro beads satisfied the fully encapsulation of particle drugs and the corresponding sustained release. Antibiotic drug tetracycline hydrochloride (TCH) was used as solid model drug particles. Read More

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October 2019