Am J Obstet Gynecol MFM 2021 Nov 30:100539. Epub 2021 Nov 30.
Richmond University Medical Center, Department of Obstetrics and Gynecology, Staten Island, New York; New York Medical College, Department of Obstetrics and Gynecology, Valhalla, New York. Electronic address:
Background: Both infectious and noninfectious causes of maternal fever have been linked to adverse neonatal outcomes including low Apgar scores, respiratory distress, hypotonia, and neonatal seizures. Even in the absence of infection, the occurrence of intrapartum fever is a strong risk factor for long-term neonatal developmental outcomes, including encephalopathy, cerebral palsy, and neonatal death.
Objective: The primary objective of this study was to compare intrapartum and postpartum maternal and fetal umbilical cord serum levels of RANTES, IFN-ɣ, IL-1 beta, IL-2, IL-4, IL-6, IL-8, IL-10, IL-13, and TNF-α between non-febrile patients, febrile patients without clinical chorioamnionitis, and febrile patient with clinical chorioamnionitis. Read More