Am J Surg Pathol 2021 May 20. Epub 2021 May 20.
Departments of Pathology Infectious Disease, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan Department of Pathology and Laboratory Medicine, Taichung Veterans General Hospital School of Medicine, Chung Shan Medical University, Taichung Department of Pathology, National Taiwan University Hospital, Taipei Department of Pathology, Ditmanson Medical Foundation Chia-Yi Christian Hospital, Chiayi Department of Pathology, E-DA Hospital, I-Shou University Department of Pathology, Kaohsiung Medical University Hospital Department of Pathology, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan Babina Diagnostics, Imphal, Manipur, India Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX.
Adult-onset immunodeficiency syndrome (AOIS) caused by anti-interferon-γ autoantibodies is an emerging disease. Affected patients present typically with systemic lymphadenopathy, fatigue, and fever. We studied 36 biopsy specimens, 31 lymph nodes, and 5 extranodal sites, of AOIS confirmed by serum autoantibody or QuantiFERON-TB Gold In-Tube assay. Read More