8,933,072 results match your criteria analysis idpparesults


Capillary partial pressure of carbon dioxide for predicting rehospitalization in preterm infants under noninvasive respiratory support with severe bronchopulmonary dysplasia.

Pediatr Pulmonol 2021 Sep 21. Epub 2021 Sep 21.

Department of Pediatrics, Seoul National University, College of Medicine, Seoul, Republic of Korea.

Background: The severity of bronchopulmonary dysplasia (BPD) is an important predictor of prognosis in preterm infants. However, the severity of BPD was determined mainly by the degree of oxygen supplementation and mode of respiratory support.

Objectives: This retrospective study aimed to examine the role of partial pressure of carbon dioxide (pCO ) in predicting rehospitalization among preterm infants with severe BPD without invasive ventilation at 36 weeks' postmenstrual age (PMA). Read More

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September 2021

Outcomes of pericardiectomy for constrictive pericarditis following mediastinal irradiation.

J Card Surg 2021 Sep 21. Epub 2021 Sep 21.

Department of Cardiovascular Surgery, Mayo Clinic, Rochester, Minnesota, USA.

Background: Pericardiectomy for postradiation constrictive pericarditis has been reported to generally have unfavorable outcomes. This study sought to evaluate surgical outcomes in a large cohort of patients undergoing pericardiectomy for radiation-associated pericardial constriction.

Methods: A retrospective analysis of all patients (≥18 years) who underwent pericardiectomy for a diagnosis of constrictive pericarditis with a prior history of mediastinal irradiation from June 2002 to June 2019 was conducted. Read More

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September 2021

O-GlcNAcylation inhibits hepatic stellate cell activation.

J Gastroenterol Hepatol 2021 Sep 21. Epub 2021 Sep 21.

Institute of Digestive Disease and Department of Medicine and Therapeutics, State Key Laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, SAR, China.

Protein O-GlcNAcylation is a critical post-translational modification regulating gene expression and fundamental cell functions. O-GlcNAc transferase (OGT) emerged as a key regulator of liver pathophysiology and disease. In this study, we aimed to evaluate the role of OGT in hepatic stellate cells (HSCs) and its consequent role in liver fibrosis. Read More

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September 2021

3D MRI in Osteoarthritis.

Semin Musculoskelet Radiol 2021 Jun 21;25(3):468-479. Epub 2021 Sep 21.

Department of Radiology & Nuclear Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

Osteoarthritis (OA) is among the top 10 burdensome diseases, with the knee the most affected joint. Magnetic resonance imaging (MRI) allows whole-knee assessment, making it ideally suited for imaging OA, considered a multitissue disease. Three-dimensional (3D) MRI enables the comprehensive assessment of OA, including quantitative morphometry of various joint tissues. Read More

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3D MRI of the Knee.

Semin Musculoskelet Radiol 2021 Jun 21;25(3):455-467. Epub 2021 Sep 21.

Section of Musculoskeletal Imaging, Imaging Institute, Cleveland Clinic, Cleveland, Ohio.

Three-dimensional (3D) magnetic resonance imaging (MRI) of the knee is widely used in musculoskeletal (MSK) imaging. Currently, 3D sequences are most commonly used for morphological imaging. Isotropic 3D MRI provides higher out-of-plane resolution than standard two-dimensional (2D) MRI, leading to reduced partial volume averaging artifacts and allowing for multiplanar reconstructions in any plane with any thickness from a single high-resolution isotropic acquisition. Read More

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Expectant Versus Interventionist Care in the Management of Severe Preeclampsia Remote from Term: A Systematic Review.

Rev Bras Ginecol Obstet 2021 Aug 21;43(8):627-637. Epub 2021 Sep 21.

Department of Obstetrics and Gynecology, Universidad Nacional de Colombia, Bogotá, Colombia.

Objective:  To compare the effects of expectant versus interventionist care in the management of pregnant women with severe preeclampsia remote from term.

Data Sources:  An electronic search was conducted in the Medical Literature Analysis and Retrieval System Online (MEDLINE), Excerpta Medica Database (EMBASE), Cochrane Central Register of Controlled Trials (CENTRAL), Latin American and Caribbean Health Sciences Literature (LILACS, for its Spanish acronym), World Health Organization's International Clinical Trials Registry Platform (WHO-ICTRP), and OpenGrey databases. The International Federation of Gynecology and Obstetrics (FIGO, for its French acronym), Royal College of Obstetricians and Gynaecologists (RCOG), American College of Obstetricians and Gynecologists (ACOG), and () websites were searched for conference proceedings, without language restrictions, up to March 25, 2020. Read More

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Impact of Plasmatic Progesterone on the Day of Frozen Embryo Transfer in Hormone-induced Cycles.

Rev Bras Ginecol Obstet 2021 Aug 21;43(8):608-615. Epub 2021 Sep 21.

Instituto Valenciano de Infertilidad, Lisboa, Portugal.

Objective:  To establish a relationship between serum progesterone values on the day of frozen blastocyst transfer in hormone-replaced cycles with the probability of pregnancy, miscarriage or delivery.

Methods:  This was an ambispective observational study including all frozen-thawed embryo transfer cycles performed at our department following in vitro fecundation from May 2018 to June 2019. The outcomes evaluated were β human chorionic gonadotropin (β-hCG)-positive pregnancy and delivery. Read More

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Concordance Between Clinical and Laboratory Diagnosis of Abnormal Vaginal Discharge in Chilean Women.

Rev Bras Ginecol Obstet 2021 Aug 21;43(8):600-607. Epub 2021 Sep 21.

Preclinical Sciences Department.

Objective:  To determine the concordance between the clinical diagnosis of women with abnormal vaginal discharge (AVD) and laboratory results using molecular detection and observation of the vaginal microbiota.

Methods:  Cross-sectional study conducted in 2018 in Temuco, Chile. A total of 25 midwives from 12 health centers participated. Read More

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Perioperative hyperbaric oxygen treatment and postoperative complications following secondary breast reconstruction after radiotherapy: a case-control study of 45 patients.

Diving Hyperb Med 2021 Sep;51(3):288-294

Department of Plastic Surgery, Radboud University Medical Center, Nijmegen, The Netherlands.

Introduction: Radiotherapy reduces the risk of locoregional recurrence of breast cancer. As a side-effect, tissue can become hypocellular, hypovascular, and hypoxic and late radiation tissue injury can develop months or years later. Radiotherapy increases the risk of complications following secondary breast reconstruction. Read More

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September 2021

Effect of hyperbaric oxygen treatment on patients with reduced left ventricular ejection fraction.

Diving Hyperb Med 2021 Sep;51(3):256-263

Service de Médecine Hyperbare, Hôtel-Dieu de Lévis, Québec, Canada.

Introduction: Hyperbaric oxygen treatment (HBOT) is available to a wide spectrum of patients, many with significant co-morbidities. Considering its effects on cardiac physiology and reports of pulmonary oedema following exposure, concerns exist about the safety of patients with compromised cardiac function. Few studies have described adverse events occurring during HBOT and even fewer reports address events arising in the hours following HBOT. Read More

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September 2021

Haploidentical vs. sibling, unrelated, or cord blood hematopoietic cell transplantation for acute lymphoblastic leukemia.

Blood Adv 2021 Sep 21. Epub 2021 Sep 21.

University of Virginia, Charlottesville, Virginia, United States.

The role of haploidentical hematopoietic cell transplantation (HCT) using post-transplant cyclophosphamide (PTCy) for acute lymphoblastic leukemia (ALL) is being defined. We performed a retrospective, multivariate analysis comparing outcomes of HCT approaches by donor for adults with ALL in remission. The primary objective was to compare overall survival (OS) between haploidentical HCT using PTCy and HLA-matched sibling donor (MSD), 8/8 HLA-matched unrelated donor (MUD) , 7/8 HLA-matched UD, or umbilical cord blood (UCB) HCT. Read More

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September 2021

Integrated safety analysis of umbralisib, a dual PI3Kδ/CK1ε inhibitor, in relapsed/refractory lymphoid malignancies.

Blood Adv 2021 Sep 21. Epub 2021 Sep 21.

TG Therapeutics, Inc., New York, New York, United States.

Phosphoinositide 3-kinase-delta (PI3Kδ) inhibitors are active in lymphoid malignancies, though associated toxicities can limit their use. Umbralisib is a dual inhibitor of PI3Kδ and casein kinase-1ε (CK1ε). This study analyzed integrated comprehensive toxicity data from 4 open-label, phase 1 and 2 studies that included 371 adult patients (median age, 67 years) with relapsed/refractory non-Hodgkin lymphoma (follicular lymphoma [n = 147]; marginal zone lymphoma [n = 82]; diffuse large B-cell lymphoma/mantle cell lymphoma [n = 74]; chronic lymphocytic leukemia [n = 43]; and other [n = 25]) who were treated with recommended phase 2 dose of umbralisib 800 mg or higher once daily. Read More

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September 2021

Analysis of Cross-Reactivity and Allergic Symptoms of 19 Allergens: Results from NHANES 2005-2006.

Int Arch Allergy Immunol 2021 Sep 21:1-10. Epub 2021 Sep 21.

Department of Otolaryngology-Head and Neck Surgery, Renmin Hospital of Wuhan University, Wuhan, China.

Introduction: We explored the cross-reactivity among 19 common allergen sources and evaluated the influence of serum IgE concentrations and the number of sensitized allergens on the incidence of allergic symptoms.

Methods: We conducted this cross-sectional analysis using data from the National Health and Nutrition Examination Survey (NHANES) 2005-2006 which is a program of studies designed to assess the health and nutritional status of adults and children in the USA. After excluding participants with missing data from the allergen IgE test, allergy questionnaire, and respiratory health questionnaire, a total of 7,224 participants aged 6 years and older were included, as children younger than 6 years old did not complete all 19 allergen-specific IgE tests. Read More

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September 2021

Ordered hexagonal patterns via Notch-Delta signaling.

Phys Biol 2021 Sep 21. Epub 2021 Sep 21.

Physics, Northeastern University, Dept. of Physics, Northeastern Univ., Boston, Massachusetts, 02115-5005, UNITED STATES.

Many developmental processes in biology utilize Notch-Delta signaling to construct an ordered pattern of cellular differentiation. This signaling modality is based on nearest-neighbor contact, as opposed to the more familiar mechanism driven by the release of diffusible ligands. Here, exploiting this ``juxtacrine" property, we present an exact treatment of the pattern formation problem via a system of nine coupled ordinary differential equations. Read More

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September 2021

Cortical network and connectivity underlying hedonic olfactory perception.

J Neural Eng 2021 Sep 21. Epub 2021 Sep 21.

Centro di Ricerca "E. Piaggio", University of Pisa, Largo Lucio Lazzarino, 1, Pisa, Pisa, PI, 56122, ITALY.

Objective: The emotional response to olfactory stimuli implies the activation of a complex cascade of events triggered by structures lying in the limbic system. However, little is known about how this activation is projected up to cerebral cortex and how different cortical areas dynamically interact each other.

Approach: In this study, we acquired EEG from human participants performing a passive odor-perception task with odorants conveying positive, neutral and negative valence. Read More

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September 2021

Aerodynamic analysis of hummingbird-like hovering flight.

Bioinspir Biomim 2021 Sep 21. Epub 2021 Sep 21.

Department of Aerospace Engineering, National University of Sciences and Technology, College of Aeronautical Engineering, Risalpur, Islamabad, 44000, PAKISTAN.

Flapping wing micro aerial vehicles are studied as the substitute for fixed and rotary wing micro aerial vehicles because of the advantages such as agility, maneuverability, and employability in confined environments. Hummingbird's sustainable hovering capability inspires many researchers to develop micro aerial vehicles with similar dynamics. In this research, a wing of a ruby-throated hummingbird is modeled as an insect wing using membrane and stiffeners. Read More

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September 2021

Emergence of non-trivial polar topologies hidden in singular stress field in SrTiO3: Topological strain-field engineering.

J Phys Condens Matter 2021 Sep 21. Epub 2021 Sep 21.

Department of Mechanical Engineering and Science, Kyoto University, Kyoto University, Nishikyo-ku, Kyoto, 615-8540, JAPAN.

Discovery of non-trivial topological structures in condensed matters holds promise in novel technological paradigms. In contrast to ferromagnetics, where a variety of topological structures such as vortex, meron, and skyrmion have been discovered, only few topological structures can exist in ferroelectrics due to the lack of non-collinear interaction like the Dzyaloshinskii-Moriya interaction in ferromagnetics. Here, we demonstrate that polarization structures with a wide range of topological numbers (winding number n from -3 to +1) can be mechanically excited and designed by the mode-I singular stress field formed near the crack-tip in incipient ferroelectric SrTiO3. Read More

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September 2021

Comparison of impedance cardiography and cardiac magnetic resonance imaging for the evaluation of cardiac function in early-stage breast cancer patients.

Physiol Meas 2021 Sep 21. Epub 2021 Sep 21.

ASTEM Research Centre, School of Sport and Exercise Sciences, College of Engineering, Swansea University, Swansea, UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND.

Objective: Breast cancer treatment can negatively impact cardiac function in some breast cancer patients. Current methods (MUGA, echocardiography) used in clinical practice to detect abnormal cardiac changes as a result of treatment suffer from important limitations. Use of alternative techniques that would offer safe, inexpensive and non-invasive cardiac function assessment in this population would be highly advantageous. Read More

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September 2021

Decommissioning procedure and induced activation levels, calculations and measurements in an 18 MeV Medical Cyclotron.

J Radiol Prot 2021 Sep 21. Epub 2021 Sep 21.

San Raffaele Hospital, Milano, Lombardia, ITALY.

The present article describes the decommissioning of a self-shielded 18 MeV medical cyclotron IBA Cyclone 18/9 after 14 years of operation. A Monte Carlo simulation of the possible nuclear reactions was performed in order to plan the decommissioning activities. During the cyclotron dismantling, the activities of the cyclotron components, concrete wall and floor samples were measured. Read More

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September 2021

Identification of colorectal cancer associated biomarkers: an integrated analysis of miRNA expression.

Aging (Albany NY) 2021 Sep 21;13(undefined). Epub 2021 Sep 21.

Faculty of Medicine and Biomedical Sciences (FMCB), University of Algarve, Campus de Gambelas, Faro 8005-139, Portugal.

Colorectal cancer is one of the leading causes of cancer-related deaths worldwide. This complex disease still holds severe problems concerning diagnosis due to the high invasiveness nature of colonoscopy and the low accuracy of the alternative diagnostic methods. Additionally, patient heterogeneity even within the same stage is not properly reflected in the current stratification system. Read More

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September 2021

When in America, do as the Americans? The evolution of health behaviors and outcomes across immigrant cohorts.

Econ Hum Biol 2021 Sep 14;43:101063. Epub 2021 Sep 14.

Department of Economics, Illinois Wesleyan University, 1402 Park Street, SFH 320, Bloomington, IL 61702, USA. Electronic address:

This study seeks to understand US immigrants' health-related behaviors and outcomes across arrival cohorts. We simultaneously examine risky consumption choices (smoking and drinking) and physical health conditions (asthma, diabetes, vision problems, and coronary heart diseases) using data from the National Health Interview Surveys (1989-2018). We incorporate cohort fixed-effects and the interactions between cohort effects and years since immigration into our empirical framework to capture the dynamics of immigrant health over time. Read More

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September 2021

Pheophorbide co-encapsulated with Cisplatin in folate-decorated PLGA nanoparticles to treat nasopharyngeal carcinoma: Combination of chemotherapy and photodynamic therapy.

Colloids Surf B Biointerfaces 2021 Sep 18;208:112100. Epub 2021 Sep 18.

Department of Otolaryngology, Head and Neck Surgery, The 901st Hospital of the Joint Logistics Support Force of PLA, Hefei, Anhui 230031, China. Electronic address:

The adverse effect and drug resistance of Cisplatin (CDDP) could be potential reduced by delivering in targeted nanoparticles and by combining with adjuvant therapy such as photodynamic therapy. In this study, F/CDPR-NP was formulated and characterized for all the physicochemical, biological and in vivo analysis. The results obtained from various in vitro and biological studies showed that encapsulation of CDDP and PBR in PLGA nanoparticles results in controlled release of encapsulated drugs and exhibited significantly low cell viability in CNE-1 and HNE-1 cancer cells. Read More

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September 2021

Reducing arsenic toxicity using the interfacial oxygen nanobubble technology for sediment remediation.

Water Res 2021 Sep 11;205:117657. Epub 2021 Sep 11.

Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, PR China; Integrated Water-Energy-Food Facility (iWEF), School of Animal, Rural, and Environmental Sciences, Nottingham Trent University, Nottinghamshire NG25 0QF, United Kingdom. Electronic address:

The arsenic (As)-bearing eutrophic waters may suffer from the dual conditions of harmful algal blooms and release of As, driven by algal-induced hypoxia/anoxia. Here, we investigate the use of interfacial oxygen (O) nanobubble technology to combat the hypoxia and control As exposure in simulated mesocosm experiments. It was observed that remediation of algal-induced hypoxia at the sediment-water interfaces (SWI) by application of O nanobubbles reduced the level of dissolved As from 23. Read More

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September 2021

Reduction of cytotoxicity and DNA double-strand break effects of wastewater by ferrate(VI): Roles of oxidation and coagulation.

Water Res 2021 Sep 15;205:117667. Epub 2021 Sep 15.

Environmental Simulation and Pollution Control State Key Joint Laboratory, State Environmental Protection Key Laboratory of Microorganism Application and Risk Control (SMARC), School of Environment, Tsinghua University, Beijing 100084, China.

Ferrate(VI) (Fe(VI)) can oxidize individual pollutants, but the pollutant oxidation does not necessarily result in toxicity reduction. Besides, Fe(VI) resultant Fe(III) particles has previously been used to remove heavy metals, but its influence on organic matter and toxicity of wastewater is unknown. This study investigated influence of Fe(VI) on the cytotoxicity and DNA double-strand break (DSB) effects of secondary effluents from wastewater treatment plants to Chinese hamster ovary cells. Read More

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September 2021

Prediction of mortality in COVID-19 through combing CT severity score with NEWS, qSOFA, or peripheral perfusion index.

Am J Emerg Med 2021 Sep 2;50:546-552. Epub 2021 Sep 2.

Department of Internal Medicine, Faculty of Medicine, Çanakkale Onsekiz Mart University, 17020 Çanakkale, Turkey.

Introduction: The assessment of disease severity and the prediction of clinical outcomes at early disease stages can contribute to decreased mortality in patients with Coronavirus disease 2019 (COVID-19). This study was conducted to develop and validate a multivariable risk prediction model for mortality with using a combination of computed tomography severity score (CT-SS), national early warning score (NEWS), and quick sequential (sepsis-related) organ failure assessment (qSOFA) in COVID-19 patients.

Methods: We retrospectively collected medical data from 655 adult COVID-19 patients admitted to our hospital between July and November 2020. Read More

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September 2021

Pulmonary embolism and COVID-19: A comparative analysis of different diagnostic models performance.

Am J Emerg Med 2021 Sep 18;50:526-531. Epub 2021 Sep 18.

Cardiology Department, Centro Hospitalar Universitário Lisboa Norte, CAML, CCUL, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal.

Objective: Pulmonary embolism (PE) is a common complication of SARS-CoV-2 infection. Several diagnostic prediction rules based on pretest probability and D-dimer have been validated in non-COVID patients, but it remains unclear if they can be safely applied in COVID-19 patients. We aimed to compare the diagnostic accuracy of the standard approach based on Wells and Geneva scores combined with a standard D-dimer cut-off of 500 ng/mL with three alternative strategies (age-adjusted, YEARS and PEGeD algorithms) in COVID-19 patients. Read More

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September 2021

Altered functional connectivity in newly diagnosed benign epilepsy with unilateral or bilateral centrotemporal spikes: A multi-frequency MEG study.

Epilepsy Behav 2021 Sep 18;124:108276. Epub 2021 Sep 18.

Department of Neurology, Nanjing Brain Hospital, Nanjing Medical University, Nanjing, Jiangsu 210029, China. Electronic address:

Objective: Rolandic epilepsy (RE) is one of the most common forms of epilepsy syndromes in children. The condition is usually accompanied with either unilateral or bilateral centrotemporal epileptic discharge. Despite the term "benign", many studies have reported that children with benign epilepsy with centrotemporal spikes (BECTS) display a range of pervasive cognitive difficulties. Read More

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September 2021

Spectroscopic investigation on the binding interactions between graphene quantum dots and carbonic anhydrase.

Spectrochim Acta A Mol Biomol Spectrosc 2021 Sep 10;265:120369. Epub 2021 Sep 10.

State Key Laboratory of Heavy Oil Processing, College of Chemical Engineering, China University of Petroleum (East China), Qingdao 266580, China. Electronic address:

As a new member of the nanomaterials family, ultrasmall graphene quantum dots (GQDs) have shown broad application prospects in the field of biomedicine, but the analysis of their biological effects at the molecular level is yet limited. Herein, carbonic anhydrase (CA) was selected as a model protein to assess the interactions between GQDs and biomacromolecules. A range of spectroscopic techniques were employed to systematically investigate the binding interactions between GQDs and CA and the catalytic function of CA in the presence of GQDs was evaluated. Read More

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September 2021

Highly accurate diagnosis of lung adenocarcinoma and squamous cell carcinoma tissues by deep learning.

Spectrochim Acta A Mol Biomol Spectrosc 2021 Sep 14;265:120400. Epub 2021 Sep 14.

State Key Laboratory of Tribology, Tsinghua University, Beijing 100084, China.

Intraoperative detection of the marginal tissues is the last and most important step to complete the resection of adenocarcinoma and squamous cell carcinoma. However, the current intraoperative diagnosis is time-consuming and requires numerous steps including staining. In this paper, we present the use of Raman spectroscopy with deep learning to achieve accurate diagnosis with stain-free process. Read More

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September 2021