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Osteochondral lesion of the talus: What are we talking about?

Orthop Traumatol Surg Res 2021 Sep 18:103068. Epub 2021 Sep 18.

15, rue Ampère, 92500 Rueil Malmaison, France.

Introduction: The analysis of osteochondral lesions of talus (OLT) is currently mostly descriptive, not permitting an understanding of the different nosological frameworks of these lesions. Better knowledge of the characteristics of patients with OLT should make it possible to optimize the surgical indications and anticipate the associated lesions, which should not be overlooked. The main objective of this study was, therefore, to assess the characteristics of patients with OLT, and to analyze the lesions encountered. Read More

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September 2021

The -592C>A Variation of IL-10 Gene and Susceptibility to Chronic Periodontitis: A Genetic Association Study and In-Silico Analysis.

J Oral Biosci 2021 Sep 18. Epub 2021 Sep 18.

Department of Periodontology, Torabinejad Dental Research Center, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran.

Objectives: Chronic periodontitis (CP) is a common inflammatory disorder with a considerable impact of genetic variations in the interleukin family on predisposition to this disease. This study aimed to investigate the association between the -592C>A polymorphism of the interleukin 10 (IL-10) gene with CP risk in an Iranian population. This experimental study was followed by a meta-analysis and in silico examination. Read More

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September 2021

Are Patient-Reported Drug Allergies Associated with Prosthetic Joint Infections and Functional Outcomes Following Total Hip and Knee Arthroplasty?

J Arthroplasty 2021 Sep 18. Epub 2021 Sep 18.

NYU Langone Orthopedic Hospital, 301 E 17th St, Suite 1402, New York, NY, 10003, USA.

Background: The purpose of this study is to determine if the number and types of patient-reported drug allergies are associated with prosthetic joint infection (PJI) and functional outcomes following total joint arthroplasty (TJA).

Methods: This was a retrospective review of all patients who underwent a primary, elective total hip (THA) or knee arthroplasty (TKA) over a 10-year period at a single academic institution. Demographic, clinical information, and number and type of patient-reported drug allergy was collected. Read More

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September 2021

Functional Deficit of Sense Organs as a risk factor for Cognitive Functional Disorder in Chinese Community Elderly People.

Int J Clin Pract 2021 Sep 21:e14905. Epub 2021 Sep 21.

Mental Health Center, The First Hospital of Hebei Medical University, Shijiazhuang, China.

Objective: To explore the relationship between mild cognitive impairment (MCI) and sense organs functional deficit in community elderly people.

Methods: 3095 community elderly people above 60 years in Hebei Province were selected by cross-sectional random cluster sampling method, who were evaluated face-to-face for general demographic data, the condition of sense organs functional deficit (vision, hearing, gustation, olfactory sensation, taste) and cognitive function by Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA).

Results: A total of 3075 valid questionnaires were obtained. Read More

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September 2021

Poverty and health inequalities: Perceptions of social work students and nursing students.

Int Nurs Rev 2021 Sep 21. Epub 2021 Sep 21.

University of Hawai'i, Myron B Thompson School of Social Work, Manoa, Hawaii, USA.

Aim: This study describes student perceptions on health inequalities and causes of poverty.

Background: As frontline providers, social workers and nurses are expected to engage with patients from socioeconomically diverse backgrounds.

Methods: In this cross-sectional study, a socio-demographic questionnaire, a questionnaire on health inequalities and the Perceived Causes of Poverty Scale were administered using a convenience sample of 155 students in social work and 266 students in nursing undergraduate programmes at a state university in Turkey. Read More

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September 2021

Prevalence and factors associated with family planning during COVID-19 pandemic in Bangladesh: A cross-sectional study.

PLoS One 2021 21;16(9):e0257634. Epub 2021 Sep 21.

Department of Neuroscience, University of Minnesota, Minneapolis, MN, United States of America.

Background And Objectives: The COVID-19 pandemic has negatively impacted health systems worldwide, including in Bangladesh, limiting access to family planning information (FP) and services. Unfortunately, the evidence on the factors linked to such disruption is limited, and no study has addressed the link among Bangladeshis. This study aimed to examine the socioeconomic, demographic, and other critical factors linked to the use of FP in the studied areas during the COVID-19 pandemic. Read More

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September 2021

The Association Between Patient Satisfaction and Mode of Visit (Telemedicine Versus In-Person) in a Large Orthopaedic Practice During the COVID-19 Pandemic Lockdown: A Retrospective Study.

J Am Acad Orthop Surg Glob Res Rev 2021 Sep 21;5(9). Epub 2021 Sep 21.

From the Jacobs School of Medicine & Biomedical Sciences, University at Buffalo, Buffalo, NY.

Background: During the novel coronavirus disease 2019 (COVID-19) pandemic, telemedicine was rapidly adopted to provide continued, efficient, and safe medical care. Little is known about patient satisfaction with telemedicine in orthopedics or the factors associated with selection of telemedicine versus face-to-face care. Thus, we examined (1) the association between patient satisfaction and mode of visit (telemedicine versus in-person) and (2) predictors of patient satisfaction in a large orthopedic practice during the onset of the pandemic. Read More

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September 2021

Prospective Associations of Pain Intensity and Substance Use in the United States Population: A Cross-Lagged Panel Analysis.

J Stud Alcohol Drugs 2021 Sep;82(5):576-583

Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut.

Objective: Pain is associated with increased risk for harmful substance use. Substance use also may increase levels of pain, suggesting that these two factors may reciprocally increase risk. The current study examined the reciprocal association between pain and substance use outcomes (i. Read More

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September 2021

A Multivariable Model of Parent Satisfaction, Pain, and Opioid Administration in a Pediatric Emergency Department.

West J Emerg Med 2021 Sep 2;22(5):1167-1175. Epub 2021 Sep 2.

University of California, Irvine, Center on Stress & Health, Orange, California.

Introduction: Children and adolescents are not impervious to the unprecedented epidemic of opioid misuse in the United States. In 2016 more than 88,000 adolescents between the ages of 12-17 reported misusing opioid medication, and evidence suggests that there has been a rise in opioid-related mortality for pediatric patients. A major source of prescribed opioids for the treatment of pain is the emergency department (ED). Read More

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September 2021

Toxicologic Exposures in California Emergency Departments in 2011 and Its Risk Factors.

West J Emerg Med 2021 Aug 22;22(5):1139-1145. Epub 2021 Aug 22.

University of California, Irvine, Department of Emergency Medicine, Irvine, California.

Introduction: Toxicologic exposures (TE) are a major preventable public health issue, with most cases due to unintentional causes. Although these cases are well documented and reported via the National Poison Data System, there is little information regarding toxicologic exposure cases in the emergency department (ED). The aim of this study was to identify demographic groups at risk for potential poisoning. Read More

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Mobile Crisis Outreach and Emergency Department Utilization: A Propensity Score-matched Analysis.

West J Emerg Med 2021 Sep 2;22(5):1086-1094. Epub 2021 Sep 2.

University of Iowa Carver College of Medicine, Department of Emergency Medicine, Iowa City, Iowa.

Introduction: Mental health and substance use disorder (MHSUD) patients in the emergency department (ED) have been facing increasing lengths of stay due to a shortage of inpatient beds. Previous research indicates mobile crisis outreach (MCO) reduces long ED stays for MHSUD patients. Our objective was to assess the impact of MCO contact on future ED utilization. Read More

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September 2021

Autologous Adipose Tissue Injection of Vocal Cords in Presbyphonia.

Otolaryngol Head Neck Surg 2021 Sep 21:1945998211045292. Epub 2021 Sep 21.

Department of Otolaryngology, Hospital Universitario de Fuenlabrada, Madrid, Spain.

Objective: This series evaluates the long-term results of autologous adipose injection (AAI) in patients older than 65 years with presbyphonia.

Study Design: Retrospective cohort study.

Setting: Academic secondary medical center. Read More

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September 2021

Naomi: a new modelling tool for estimating HIV epidemic indicators at the district level in sub-Saharan Africa.

J Int AIDS Soc 2021 Sep;24 Suppl 5:e25788

Division of Global HIV and Tuberculosis, Centers for Disease Control and Prevention, Lilongwe, Malawi.

Introduction: HIV planning requires granular estimates for the number of people living with HIV (PLHIV), antiretroviral treatment (ART) coverage and unmet need, and new HIV infections by district, or equivalent subnational administrative level. We developed a Bayesian small-area estimation model, called Naomi, to estimate these quantities stratified by subnational administrative units, sex, and five-year age groups.

Methods: Small-area regressions for HIV prevalence, ART coverage and HIV incidence were jointly calibrated using subnational household survey data on all three indicators, routine antenatal service delivery data on HIV prevalence and ART coverage among pregnant women, and service delivery data on the number of PLHIV receiving ART. Read More

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September 2021

Exploration of severe Covid-19 associated risk factor in China: meta-analysis of current evidence.

Int J Clin Pract 2021 Sep 21:e14900. Epub 2021 Sep 21.

Department of Orthopaedics, Zibo Central Hospital, 54 West Gongqingtuan Road, Zibo, 255036, Shandong province, China.

Aim: This meta-analysis aimed to explore potential risk factors for severe Covid-19.

Methods: We systemically and comprehensively retrieved the eligible study evaluating clinical differences between severe versus non-severe Covid-19. Main effect sizes were demographic characteristics, comorbidities, signs and symptoms, laboratory findings as well as radiological features of chest CT. Read More

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September 2021

Pediatric upper extremity firearm injuries: an analysis of demographic factors and recurring mechanisms of injury.

World J Pediatr 2021 Sep 21. Epub 2021 Sep 21.

Department of Surgery, Division of Plastic and Reconstructive Surgery, University of Florida College of Medicine, 100138, Gainesville, FL 32610, USA.

Background: Little is known regarding risk factors specific to pediatric upper extremity firearm injuries. The purpose of this study is to evaluate pediatric patients treated for these injuries to identify at-risk populations and recurring mechanisms of injury.

Methods: A 20-year retrospective review was conducted. Read More

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September 2021

Non-carious Cervical Lesions (NCCLs) and associated factors: a multilevel analysis in a cohort study in Southern Brazil.

J Clin Periodontol 2021 Sep 20. Epub 2021 Sep 20.

Radboud University Medical Center, Department of Dentistry, Radboud Institute for Health Sciences, Nijmegen, The Netherlands.

Aim: To investigate the prevalence of Non-carious Cervical Lesions (NCCLs) and the association with individual and tooth-related factors in adults from the 1982 Pelotas Birth Cohort.

Materials And Methods: Participants were interviewed and clinically examined at the age 31. NCCL was defined as loss of dental tissue without bacterial involvement in the cervical region. Read More

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September 2021

Capturing the dynamics of small populations: a retrospective assessment using long-term data for an island reintroduction.

J Anim Ecol 2021 Sep 21. Epub 2021 Sep 21.

Institute of Zoology, Zoological Society of London, Regent's Park, London, UK.

The art of population modelling is to incorporate factors essential for capturing a population's dynamics while otherwise keeping the model as simple as possible. However, it is unclear how optimal model complexity should be assessed, and whether this optimal complexity has been affected by recent advances in modelling methodology. This issue is particularly relevant to small populations because they are subject to complex dynamics but inferences about those dynamics are often constrained by small sample sizes. Read More

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September 2021

Predictors of Postoperative Pancreatic Fistula (POPF) After Pancreaticoduodenectomy: Clinical Significance of the Mean Platelet Volume (MPV)/Platelet Count Ratio as a New Predictor.

J Gastrointest Surg 2021 Sep 20. Epub 2021 Sep 20.

Department of Surgical Oncology, Faculty of Medicine, Fırat University Medical Faculty Hospital, Elazig, 23200, Turkey.

Purpose: In this study, it was aimed to determine the predictors of clinically relevant postoperative pancreatic fistula (CR-POPF) following pancreaticoduodenectomy (PD) and clinical significance of mean platelet volume (MPV)/total platelet count ratio (MPR) as a new predictor for CR-POPF.

Methods: A total of 105 patients who underwent PD consecutively due to periampullary located diseases were included in the study. Patients were divided into two groups as CR-POPF and no postoperative pancreatic fistula (No-POPF). Read More

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September 2021

Immune and cellular damage biomarkers to predict COVID-19 mortality in hospitalized patients.

Curr Res Immunol 2021 Sep 16. Epub 2021 Sep 16.

Department of Pulmonary Medicine, Thoracic Disease Research Unit, Mayo Clinic, Rochester, USA.

Early prediction of COVID-19 in-hospital mortality relies usually on patients' preexisting comorbidities and is rarely reproducible in independent cohorts. We wanted to compare the role of routinely measured biomarkers of immunity, inflammation, and cellular damage with preexisting comorbidities in eight different machine-learning models to predict mortality, and evaluate their performance in an independent population. We recruited and followed-up consecutive adult patients with SARS-Cov-2 infection in two different Italian hospitals. Read More

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September 2021

Assessing economic, social and environmental impacts on housing prices in Hong Kong: a time-series study of 2006, 2011 and 2016.

J Hous Built Environ 2021 Sep 16:1-25. Epub 2021 Sep 16.

Faculty of Architecture, University of Hong Kong, Shatin, New Territories, Hong Kong, China.

Given Hong Kong's unique high-density urban environment and limited land resources, more and more general public has been concerned about the living quality. Based on three waves of census data (2006, 2011 and 2016), combined with our spatial-temporal urban environmental database consisting of three local datasets of urban climate and air quality, this paper assesses the impacts of social, economic and environmental factors on the logarithm of housing prices in Hong Kong through linear regression analysis. Specifically, both supply- and demand-side economic factors have significant impacts on housing prices. Read More

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September 2021

Key factors affecting people's unwillingness to be confined during the COVID-19 pandemic in Spain: a large-scale population study.

Sci Rep 2021 Sep 20;11(1):18626. Epub 2021 Sep 20.

ELLIS Unit Alicante Foundation, Alicante, Spain.

Population confinements have been one of the most widely adopted non-pharmaceutical interventions (NPIs) implemented by governments across the globe to help contain the spread of the SARS-CoV-2 virus. While confinement measures have been proven to be effective to reduce the number of infections, they entail significant economic and social costs. Thus, different policy makers and social groups have exhibited varying levels of acceptance of this type of measures. Read More

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September 2021

Insufficient Recovery From C5 Palsy Following Anterior Cervical Decompression and Fusion.

Spine (Phila Pa 1976) 2021 Sep 20. Epub 2021 Sep 20.

Department of Orthopaedic Surgery, Gakkentoshi Hospital, Kyoto, Japan.

Study Design: Retrospective study.

Objective: To determine the risk factors for insufficient recovery from C5 palsy (C5P) following anterior cervical decompression and fusion (ADF).

Summary Of Background Data: Postoperative C5P is a frequent but unsolved complication following cervical decompression surgery. Read More

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September 2021

The association between duration of postnatal weight loss and neurodevelopment outcomes in very low birth weight infants.

Pediatr Neonatol 2021 Aug 30. Epub 2021 Aug 30.

Division of Neonatology, Children's Medical Center, Taichung Veterans General Hospital, Taichung, Taiwan.

Background: Premature births account for around 11% of the world's live births. With the improvements in survival that have been achieved in recent years, the neurological outcomes of these infants have attracted greater attention. The aim of this study was to evaluate the association between postnatal weight loss and neurodevelopment outcomes of very low birth weight premature infants. Read More

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The relationship among factors of organizational justice, organizational citizenship behavior, job satisfaction, and ease of work among Japanese nurses.

Appl Nurs Res 2021 Oct 8;61:151479. Epub 2021 Aug 8.

Department of Nursing Science, Faculty of Health and Welfare Science, Okayama Prefectural University, 111 Kuboki, Soja 719-1197, Japan. Electronic address:

Aim: This work is aimed to create a strategy to improve the nurses' working environment.

Background: As the working-age population is expected to decline in Japan, the maintenance of the nurse workforce is important. In order to create a strategy to improve the nurses' working environment, we studied the relationship among factors of organizational justice (procedural, distributive, and interactional justices), organizational citizenship behavior, job satisfaction, and ease of work. Read More

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October 2021

Factors affecting participant recruitment and retention in borderline personality disorder research: a feasibility study.

Pilot Feasibility Stud 2021 Sep 20;7(1):178. Epub 2021 Sep 20.

Department of Psychiatry and Behavioural Neurosciences, McMaster University, 1280 Main Street West, Hamilton, ON, Canada.

Background: Previous studies have shown that stigma is a major barrier to participation in psychiatric research and that individuals who participate in psychiatric research may differ clinically and demographically from non-participants. However, few studies have explored research recruitment and retention challenges in the context of personality disorders.

Aim: To provide an analysis of the factors affecting participant recruitment and retention in a study of borderline personality disorder among general psychiatric inpatients. Read More

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September 2021

Social contexts of fertility desire among non-childbearing young men and women aged 15-24 years in Nigeria.

Reprod Health 2021 Sep 20;18(1):186. Epub 2021 Sep 20.

Demography and Population Studies Programme, Schools of Public Health and Social Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Background: Reduction in ideal number of children has been suggested as a necessary precursor for fertility decline especially in high fertility countries of Western and Central Africa. In this study, we explored the social contexts of fertility desires by documenting the effects of individual, household as well as contextual characteristics among young men and women in Nigeria.

Methods: Data source was the male and female recode file of 2018 Nigeria Demographic and Health Survey. Read More

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September 2021

Study of patient characteristics, treatment patterns, testing patterns and outcomes in real-world patients with m non-small cell lung cancer.

Curr Med Res Opin 2021 Sep 21:1-22. Epub 2021 Sep 21.

Johns Hopkins Bayview Medical Center, Baltimore, Maryland, USA.

Objective: This retrospective, observational study examined patient characteristics, treatment patterns, testing patterns and outcomes of US patients receiving first-/second- or third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs).

Methods: This study used an electronic health record-derived de-identified database. Eligible patients had advanced m non-small cell lung cancer. Read More

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September 2021

The Evolving Story of Mesh Mid-urethral Slings: The Surgeon's Perspective.

J Urol 2021 Sep 21:101097JU0000000000002203. Epub 2021 Sep 21.

Section of Urology & Renal Transplantation, Virginia Mason Medical Center, Seattle, Washington.

Objective: To obtain the perspectives of surgeons who treat female stress urinary incontinence (SUI) and better understand their range of experiences with mesh mid-urethral sling (MUS) surgery.

Methods: This qualitative study recruited gynecologic and urologic surgeons who treat SUI. Surgeons were interviewed by phone and in-person using a standardized interview guide. Read More

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September 2021

U.S. racial and ethnic participation in global clinical trials by therapeutic areas.

J Clin Pharm Ther 2021 Sep 20. Epub 2021 Sep 20.

Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, USA.

What Is Known And Objective: The discussion about health equity in the United States frequently involves concerns over racial and ethnic minority under-representation in clinical trials and particularly in trials conducted in support of product approvals. The FDA has long worked to encourage diverse participation in clinical trials and through its Drug Trials Snapshots (DTS) program, the U.S. Read More

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September 2021

Fibrinogen-to-Albumin Ratio in Familial Mediterranean Fever: Association with Subclinical Inflammation.

Klin Padiatr 2021 Sep 20. Epub 2021 Sep 20.

Pediatric Nephrology, Celal Bayar University School of Medicine, Manisa, Turkey.

Background: Familial Mediterranean fever (FMF) is the most seen monogenic periodic fever syndrome characterised by bouts of fever and serositis. It is known that subclinical inflammation (SI) can persist in the symptom-free period and lead to amyloidosis even under colchicine treatment. This study aimed to evaluate the role of the fibrinogen-to-albumin ratio (FAR) in FMF and its correlation with SI. Read More

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September 2021