9,915 results match your criteria amount reactive


Sewage sludge as a source of microplastics in the environment: A review of occurrence and fate during sludge treatment.

J Environ Manage 2021 Jun 18;295:113028. Epub 2021 Jun 18.

Department of Environmental Engineering, Middle East Technical University, 06800, Ankara, Turkey. Electronic address:

Modern wastewater treatment plants (WWTPs) effectively remove microplastics (MPs) from wastewater and unsurprisingly concentrate them in sludge. Hence through its beneficial use and disposal, sludge causes secondary release pathways of an estimated average amount of 10 to 10 wastewater-based MPs to various environmental compartments yearly. Despite these numbers, studies investigating sludge are scarce. Read More

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Analysis on the application value of goal-directed fluid therapy in patients undergoing laparoscopy-assisted radical gastrectomy with fast-track anesthesia.

Am J Transl Res 2021 15;13(5):5174-5182. Epub 2021 May 15.

Department of Anesthesiology, Zhuji People's Hospital Zhuji 311800, Zhejiang Province, China.

Objective: To explore the application value of goal-directed fluid therapy (GDFT) in patients undergoing laparoscopy-assisted radical gastrectomy with fast-track anesthesia.

Methods: From December 2016 to December 2019, 74 patients who underwent laparoscopy-assisted radical gastrectomy under the concept of enhanced recovery after surgery (ERAS) in gastrointestinal Surgery department of Tongling People's Hospital were selected as research participants. They were divided into two groups: the routine group (patients were treated with conventional fluids) (n=37) and the GDFT group (patients were treated with GDFT) (n=37). Read More

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Herbicide atrazine exposure induce oxidative stress, immune dysfunction and WSSV proliferation in red swamp crayfish Procambarus clarkii.

Chemosphere 2021 Jun 15;283:131227. Epub 2021 Jun 15.

College of Animal Science and Technology, Yangzhou University, Yangzhou, 225009, China.

Atrazine is considered as a potential environmental endocrine disruptors and exhibits various toxic effects on animals. It has a great impact in the aquatic ecosystems, but there are few studies on its immunotoxicity in crustaceans. In the present study, the Procambarus clarkii were utilized to assess the immune toxicity after 0. Read More

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A comprehensive review on the analytical method, occurrence, transformation and toxicity of a reactive pollutant: BADGE.

Environ Int 2021 Jun 17;155:106701. Epub 2021 Jun 17.

School of Civil and Environmental Engineering, Nanyang Technological University, Singapore 639798, Singapore; Nanyang Environment & Water Research Institute, Nanyang Technological University, Singapore 637141, Singapore. Electronic address:

Bisphenol A diglycidyl ether (BADGE)-based epoxy resin is one of the most widely used epoxy resins with an annual production amount of several million tons. Compared with all other legacy or emerging organic compounds, BADGE is special due to its toxicity and high reactivity in the environment. More and more studies are available on its analytical methods, occurrence, transformation and toxicity. Read More

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Evaluating the safety of two human experimental intestinal ischemia reperfusion models: A retrospective observational study.

PLoS One 2021 18;16(6):e0253506. Epub 2021 Jun 18.

NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Centre+, Maastricht, The Netherlands.

Background: We developed a jejunal and colonic experimental human ischemia-reperfusion (IR) model to study pathophysiological intestinal IR mechanisms and potential new intestinal ischemia biomarkers. Our objective was to evaluate the safety of these IR models by comparing patients undergoing surgery with and without in vivo intestinal IR.

Methods: A retrospective study was performed comparing complication rates and severity, based on the Clavien-Dindo classification system, in patients undergoing pancreatoduodenectomy with (n = 10) and without (n = 20 matched controls) jejunal IR or colorectal surgery with (n = 10) and without (n = 20 matched controls) colon IR. Read More

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An insight into the mechanism of antibacterial activity by magnesium oxide nanoparticles.

J Mater Chem B 2021 Jun 18. Epub 2021 Jun 18.

Indian Institute of Technology Kharagpur, 721302, India.

The exact mechanism behind the antibacterial efficacy of nanoparticles has remained unexplored to date. This study aims to shed light the mechanism adopted using magnesium oxide nanoparticles prepared in ethyl alcohol against gram-negative and gram-positive bacterial cells, and the generation of reactive oxygen species (ROS) is proposed to be the dominant mechanism. This paradigm is supported by the quantification of the hydroxyl radical and superoxide anions produced in the nanoparticle treated and untreated bacterial solutions, and by the reduction of the antibacterial efficiency after the addition of a radical scavenger. Read More

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Extracellular Vesicles from Human Plasma Show a Distinctive Proteome and miRNome Profile in Patients with Severe Cutaneous Adverse Reactions.

Chem Res Toxicol 2021 Jun 18. Epub 2021 Jun 18.

Unidad Profesional Interdisciplinaria de Biotecnología, Instituto Politécnico Nacional, Mexico City 07340, Mexico.

Cutaneous drug-induced reactions are immune-mediated responses that can lead to life-threatening diseases such as drug reaction with eosinophilia and systemic symptoms (DRESS), Stevens-Johnson syndrome, and toxic epidermal necrolysis, collectively known as severe cutaneous adverse reactions (SCARs). Unfortunately, they cannot be predicted during drug development, and, at present, a prognostic biomarker is not available nor are validated assays for diagnosis. Thus, by using proteomic and microarray miRNA analysis, the cargo of extracellular vesicles obtained from SCARs patients was analyzed and correlated with the severity of the reaction. Read More

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Ganoderic acid T improves the radiosensitivity of HeLa cells via converting apoptosis to necroptosis.

Toxicol Res (Camb) 2021 May 13;10(3):531-541. Epub 2021 May 13.

CAS Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Hefei Institutes of Physical Science, Chinese Academy of Sciences (CAS), Hefei 230031, China.

The use of natural substances derived from traditional Chinese medicine and natural plants as safe radiosensitizing adjuvants is a new trend for cancer radiotherapy. has been used as a traditional Chinese medicine with a history of more than 2000 years. Ganoderic acid T (GAT) is a typical triterpene of , which has strong cytotoxicity to cancer cells, but whether it has radiation sensitization effect has not been explored. Read More

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Reactive Plasmacytosis: A Diagnostic Conundrum In Acute Myeloid Leukaemia.

J Ayub Med Coll Abbottabad 2021 Apr-Jun;33(2):335-338

Department of Hematology, Rehman Medical Institute, Peshawar, Pakistan.

Bone-marrow being a home to various kinds of normal hematopoietic cells, sometime becomes overcrowded by abnormal cell population in malignancies like in acute myeloid leukaemia. One such dilemma in diagnosis betides when two abnormal cell populations in bone-marrow occur at the same time. A prime example is when reactive plasmacytosis in bone-marrow eventuate in relation with acute myeloid leukaemia (AML). Read More

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Novel Strategies for Disrupting Cancer-Cell Functions with Mitochondria-Targeted Antitumor Drug-Loaded Nanoformulations.

Int J Nanomedicine 2021 9;16:3907-3936. Epub 2021 Jun 9.

Department of Basic Health Sciences, College of Applied Medical Sciences, Qassim University, Buraydah, Saudi Arabia.

Any variation in normal cellular function results in mitochondrial dysregulation that occurs in several diseases, including cancer. Such processes as oxidative stress, metabolism, signaling, and biogenesis play significant roles in cancer initiation and progression. Due to their central role in cellular metabolism, mitochondria are favorable therapeutic targets for the prevention and treatment of conditions like neurodegenerative diseases, diabetes, and cancer. Read More

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Hydrogen peroxide treated g-CN as an effective hydrophilic nanosheet for modification of polyethersulfone membranes with enhanced permeability and antifouling characteristics.

Chemosphere 2021 Sep 22;279:130616. Epub 2021 Apr 22.

Department of Chemistry, Faculty of Science, University of Mohaghegh Ardabili, P.O. Box 179, Ardabil, Iran.

In this study, first, graphitic carbon nitride was treated with hydrogen peroxide (abbreviated as HO-g-CN), then was used as a new hydrophilic nanomaterial in the fabrication of polyethersulfone (PES) mixed matrix membrane (MMM) for improving flux, protein and dye separation efficiency and antifouling properties. The HO-g-CN nanosheet was inserted into the doping solution to fabricate PES/HO-g-CN nanocomposite membrane with the non-solvent induced phase inversion procedure. The results of the SEM and AFM images and also porosity and contact angle analysis were indicated that the modified membranes with HO-g-CN had more porosity, smoother surface and more hydrophilic. Read More

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September 2021

In vivo immobilized carbonic anhydrase and its effect on the enhancement of CO absorption rate.

J Biotechnol 2021 Jun 12;336:41-49. Epub 2021 Jun 12.

Dipartimento di Ingegneria Chimica, dei Materiali e della Produzione Industriale, Università degli Studi di Napoli Federico II, P.le V. Tecchio, 80, 80125, Napoli, Italy.

Reactive absorption into aqueous solutions promoted by carbonic anhydrase (CA, E.C. 4. Read More

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Synthesis, characterization and C-H amination reactivity of nickel iminyl complexes.

Chem Sci 2019 Dec 11;11(5):1260-1268. Epub 2019 Dec 11.

Department of Chemistry and Chemical Biology, Harvard University 12 Oxford Street Cambridge Massachusetts 02138 USA

Metalation of the deprotonated dipyrrin (L)Li with NiCl(py) afforded the divalent Ni product (L)NiCl(py) () (L: 1,9-di(1-adamantyl)-5-perfluorophenyldipyrrin; py: pyridine). To generate a reactive synthon on which to explore oxidative group transfer, we used potassium graphite to reduce , affording the monovalent Ni synthon (L)Ni(py) () and concomitant production of a stoichiometric equivalent of KCl and pyridine. Slow addition of mesityl- or 1-adamantylazide in benzene to afforded the oxidized Ni complexes (L)Ni(NMes) () and (L)Ni(NAd) (), respectively. Read More

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December 2019

Dissolution of Fe from Fe-bearing minerals during the brown-carbonization processes in atmosphere.

Sci Total Environ 2021 May 29;791:148133. Epub 2021 May 29.

State Key Laboratory of Pollution Control and Resource Reuse, School of the Environment, Nanjing University, Nanjing, Jiangsu 210023, China. Electronic address:

Previous studies found Fe dissolution in atmosphere correlates to biomass burning, while the underlying mechanisms need to be further investigated. In this study, we reported a laboratory investigation about Fe dissolution behavior of two model Fe-bearing clay minerals of montmorillonite (SWy-2) and illite (IMt-2), and one standard mineral dust of Arizona test dust (AZTD) in atmospheric condition (pH = 2), after the minerals engaging into the brown-carbonization reaction with guaiacol, which is a commonly detected volatile phenol substance in biomass burning. The results show that the pre-brown-carbonization reaction promoted Fe dissolution from all the three minerals, attributing to the reduction of Fe(III) by gaseous guaiacol. Read More

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Easy Surface Functionalization and Bioconjugation of Peptides as Capture Agents of a Microfluidic Biosensing Platform for Multiplex Assay in Serum.

Bioconjug Chem 2021 Jun 11. Epub 2021 Jun 11.

Center for Advanced Biomaterials for [email protected], Istituto Italiano di Tecnologia (IIT), Largo Barsanti e Matteucci 53, 80125 Naples, Italy.

The development of assays for protein biomarkers in complex matrices is a demanding task that still needs implementation of new approaches. Antibodies as capture agents have been largely used in bioassays but their low stability, low-efficiency production, and cross-reactivity in multiplex approaches impairs their larger applications. Instead, synthetic peptides, even with higher stability and easily adapted amino acid sequences, still remain largely unexplored in this field. Read More

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Salicylic acid and nitric oxide cross-talks to improve innate immunity and plant vigor in tomato against Fusarium oxysporum stress.

Plant Cell Rep 2021 Jun 9. Epub 2021 Jun 9.

Department of Botany, Scottish Church College, Kolkata, 700006, India.

Key Message: Foliar application of SA cross-talks and induce endogenous nitric oxide and reactive oxygen species to improve innate immunity and vigor of tomato plant against Fusarium oxysporum stress. The present investigation was aimed to demonstrate the efficacy of salicylic acid (SA), as a powerful elicitor or plant growth regulator (PGR) and its cross-talk with nitric oxide (NO) in tomato against the biotic stress caused by wilt pathogen, Fusarium oxysporum f. sp. Read More

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Boronate affinity imprinted hydrogel sorbent from biphasic synergistic high internal phase emulsions reactor for specific enrichment of Luteolin.

J Colloid Interface Sci 2021 May 30;601:782-792. Epub 2021 May 30.

School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang 212013, China. Electronic address:

The dynamic coexistence of heterostructures is crucial for the synergistic function of molecularly imprinted polymers (MIPs) derived from high internal phase emulsions (HIPEs). In this work, hydrophilic boronate affinity imprinted hydrogel sorbents (H-UIO-66-NH-IHIPEs) were prepared by biphasic synergistic HIPEs droplet reactors filled with reactive microencapsulation system, and used to capture and separate cis-diol containing luteolin (LTL) from complex extraction samples with high selectivity. As the main solid emulsifier, UiO-66-NH, prototype zirconium-based metal-organic frameworks (MOFs) greatly improves the mechanical performance of the hydrogel, whilst preventing overuse of surfactants. Read More

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Facile and scalable design of light-emitting and ROS-generating hybrid materials made of polyurea gels embedding a molybdenum cluster-based salt.

Dalton Trans 2021 Jun 9. Epub 2021 Jun 9.

Universidade de Franca, Av. Dr Armando Salles Oliveira 201, 14404-600 Franca, SP, Brazil.

Here, we demonstrate a facile and scalable preparation via sol-gel chemistry of hybrid polyurea gels containing various amounts of a phosphorescent inorganic octahedral molybdenum cluster-based ternary salt, namely Cs2Mo6Br14. The influence of the Cs2Mo6Br14 content (1-10 wt%) on the polyurea matrix and its physical properties are studied in depth by Fourier transform infrared spectroscopy (FTIR), differential scanning calorimetry (DSC) and X-ray fluorescence microanalysis (μ-XRF). Regardless of the amount of cluster loaded into the polyurea, the integrity of these species was preserved and their dispersion is homogeneous as shown by μ-XRF mapping. Read More

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Ferrous hemoglobin and hemoglobin-based oxygen carriers acting as a peroxidase can inhibit oxidative damage to endothelial cells caused by hydrogen peroxide.

Artif Organs 2021 Jun 8. Epub 2021 Jun 8.

College of Life Science, Northwest University, Xi'an, P.R. China, 710069.

Oxidative damage caused by the ferryl hemoglobin is one of the major clinical adverse reactions of hemoglobin-based oxygen carriers (HBOCs), while the production of reactive oxygen species in a pathological state can oxidize hemoglobin (HbFe ) to ferryl Hb, which can then enter the pseudoperoxidase cycle, making hemoglobin highly toxic. In this study, we found that ferrous hemoglobin and polymerized porcine hemoglobin (one of the HBOCs) have the peroxidase activity different from the pseudoperoxidase activity of ferric hemoglobin. Ferrous hemoglobin can catalyze the reaction of tyrosine (Tyr) with hydrogen peroxide. Read More

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Facile fabricating of rGO and Au/rGO nanocomposites using Brassica oleracea var. gongylodes biomass for non-invasive approach in cancer therapy.

Sci Rep 2021 Jun 7;11(1):11900. Epub 2021 Jun 7.

Faculty of Physics, University of Tabriz, Tabriz, Iran.

In this study, we report a facile green-synthesis route for the fabrication of reduced graphene oxide (rGO) using biomass of Brassica oleracea var. gongylodes (B. oleracea). Read More

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Construction of MoO nanopaticles /g-CN nanosheets 0D/2D heterojuntion photocatalysts for enhanced photocatalytic degradation of antibiotic pollutant.

Chemosphere 2021 May 29;282:131049. Epub 2021 May 29.

College of Environmental Science and Engineering, Hunan University, Changsha, 410082, China; Key Laboratory of Environmental Biology and Pollution Control, Hunan University, Ministry of Education, Changsha, Hunan, 410082, China.

A new type of 0D-2D Z-scheme heterojunction photocatalyst (MoO/g-CN) was successfully prepared via simple hydrothermal calcination method. The catalytic activities of MoO/g-CN was evaluated by the degradation effect of tetracycline. The results indicated that the 0D-2D MoO/g-CN Z-scheme heterojunction was significantly better than that of original g-CN. Read More

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Determination of Oxidative Stress and Antioxidant Enzyme Activity for Physiological Phenotyping During Heavy Metal Exposure.

Methods Mol Biol 2021 ;2326:241-249

College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, Zhejiang, China.

The overproduction of reactive oxygen species during abiotic stress in plants causes oxidative stress that damage the cell normal functions. For reactive oxygen species (ROS) scavenging, plants developed a defense system with antioxidant enzymes. To measure the oxidative stress and antioxidant enzymes activity spectral enzymatic analysis was used, that is material-intensive, time-consuming, and inefficient. Read More

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January 2021

The effect of redox signaling on extracellular matrix changes in diabetic wounds leading to amputation.

Biochem Biophys Rep 2021 Jul 21;26:101025. Epub 2021 May 21.

Vascular and Endovascular Surgery Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Introduction: & Objectives: Redox signaling is a critical regulator in the process of wound healing. This signaling pathway can be effective in the development or healing of diabetic ulcers through the ECM.In this study, the structure of extracellular matrix investigated in relation to redox signaling in the tissue of patients with diabetic ulcers that lead to organ amputation. Read More

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Refinement of the Griess method for measuring nitrite in biological samples.

J Microbiol Methods 2021 Jun 5;187:106260. Epub 2021 Jun 5.

Departamento de Biología, División de Ciencias Naturales y Exactas, Universidad de Guanajuato, Noria Alta S/N 36050, Guanajuato, Gto, Mexico. Electronic address:

Nitric oxide (NO) is a reactive gas that participates in many physiological as well as pathogenic processes in higher eukaryotic organisms. Inflammatory responses elicit higher levels of this molecule. Nevertheless, there are many technical challenges to accurately measure the amount of NO produced. Read More

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Potentiation of flutamide-induced hepatotoxicity in mice by Xian-Ling-Gu-Bao through induction of CYP1A2.

J Ethnopharmacol 2021 Jun 4;278:114299. Epub 2021 Jun 4.

Key Laboratory of Basic Pharmacology of Ministry of Education, Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, 563003, China. Electronic address:

Ethnopharmacological Relevance: Xian-Ling-Gu-Bao (XLGB) Fufang is herbal formula widely used to treat osteoporosis and other bone disorders. Because of its commonality in the clinical use, there is a safety concern over the use of XLGB combined with other androgen deprivation therapy (ADT) drugs such as flutamide (FLU) that is associated with reduced bone density. To date, there have been no evaluations on the side effects of the drug-drug interaction between XLGB and FLU. Read More

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Hexavalent chromium reduction by zero-valent magnesium particles in column systems.

J Environ Manage 2021 Jun 2;293:112905. Epub 2021 Jun 2.

Laboratory of Sanitary and Environmental Engineering, Department of Environmental Engineering, University of Calabria, P. Bucci, 87036, Arcavacata di Rende, CS, Italy.

The discharge of hexavalent chromium in aquatic environments represents an issue of great concern. The chemical reduction of Cr to Cr, which is less mobile and harmful, is a suitable approach for chromium removal. In this regard, in comparison to other reactive metals, the use of zero-valent magnesium (ZVM) has several advantages. Read More

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Highly efficient photoelectrochemical removal of atrazine and the mechanism investigation: Bias potential effect and reactive species.

J Hazard Mater 2021 08 18;415:125681. Epub 2021 Mar 18.

School of Chemical Science and Engineering, and Shanghai Key Lab of Chemical Assessment and Sustainability, Tongji University, 1239 Siping Road, Shanghai 200092, China. Electronic address:

In this work, efficient photoelectrochemical (PEC) removal of atrazine, one of the most widely used chemical herbicides in the world, was obtained by adjusting the bias potential applied on the photo-anode, and the optimal atrazine removal efficiency reached 96.8% at the potential of 0.2 V vs. Read More

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Discovery of novel purinylthiazolylethanone derivatives as anti-Candida albicans agents through possible multifaceted mechanisms.

Eur J Med Chem 2021 Oct 25;221:113557. Epub 2021 May 25.

Institute of Bioorganic & Medicinal Chemistry, Key Laboratory of Luminescence Analysis and Molecular Sensing, Ministry of Education, School of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, China. Electronic address:

An unprecedented amount of fungal and fungal-like infections has recently brought about some of the most severe die-offs and extinctions due to fungal drug resistance. Aimed to alleviate the situation, new effort was made to develop novel purinylthiazolylethanone derivatives, which were expected to combat the fungal drug resistance. Some prepared purinylthiazolylethanone derivatives possessed satisfactory inhibitory action towards the tested fungi, among which compound 8c gave a MIC value of 1 μg/mL against C. Read More

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October 2021

Porphyrin-Containing MOFs and COFs as Heterogeneous Photosensitizers for Singlet Oxygen-Based Antimicrobial Nanodevices.

ACS Appl Mater Interfaces 2021 Jun 4;13(23):26651-26672. Epub 2021 Jun 4.

Département de Chimie, Université de Sherbrooke, Sherbrooke, Quebec J1K 2R1, Canada.

Visible-light irradiation of porphyrin and metalloporphyrin dyes in the presence of molecular oxygen can result in the photocatalytic generation of singlet oxygen (O). This type II reactive oxygen species (ROS) finds many applications where the dye, also called the photosensitizer, is dissolved (i.e. Read More

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Sensory and Physicochemical Quality Characteristics of Haddock Fish Cake Enriched with Atlantic Mackerel Quality of Fish Cakes.

Food Technol Biotechnol 2021 Mar;59(1):4-15

Department of Biotechnology and Food Science, Norwegian University of Science and Technology, Sem Saelands vei 6/8, 7491 Trondheim, Norway.

Research Background: It is desirable to increase the consumption of pelagic fish rich in long-chain omega-3 fatty acids. Partial replacement of traditionally used white fish species by pelagic fish will increase the content of omega-3 fatty acids, and thus improve the nutritional value but it may also affect the consumer acceptance. The aim of this study is to assess the physicochemical and sensory quality of novel fish cake prototypes prepared from haddock and mackerel mince. Read More

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