1 results match your criteria allergen-dna-modified dendritic

  • Page 1 of 1

Suppression of allergic inflammation by allergen-DNA-modified dendritic cells depends on the induction of Foxp3+ Regulatory T cells.

Scand J Immunol 2008 Feb;67(2):140-51

Institute of Respiratory Medicine, Xinqiao Hospital, Third Military Medical University, Chongqing, China.

CD4(+)CD25(+)Foxp3(+)Regulatory T cells (Tregs) play important roles in regulating allergic inflammation. To analyse if allergen-DNA-modified dendritic cells (DC) can suppress allergic responses and what roles Treg cells play in DC-based allergen-specific immunotherapy. Immature DC were transfected with retrovirus encoding Der p2 DNA, and administered to mice that sensitized and challenged with Der p2 protein. Read More

View Article and Full-Text PDF
February 2008
  • Page 1 of 1