Chem Rev 2020 Aug 3. Epub 2020 Aug 3.
Department of Chemistry, National Tsing-Hua University, Hsinchu 30013, Taiwan, Republic of China.
Catalytic transformations involving metal carbenes are considered one of the most important aspects of homogeneous transition metal catalysis. Recently, gold-catalyzed generation of gold carbenes from readily available alkynes represents a significant advance in metal carbene chemistry. This Review summarizes the advances in the gold-catalyzed nitrene-transfer reactions of alkynes with nitrogen-transfer reagents, such as azides, nitrogen ylides, isoxazoles, and anthranils, and gold-catalyzed carbene-transfer reactions, involving oxygen atom-transfer reactions of alkynes with nitro compounds, nitrones, sulfoxides, and pyridine -oxides, through the presumable α-imino gold carbene and α-oxo gold carbene intermediates, respectively. Read More