Environ Pollut 2022 Mar 27;296:118746. Epub 2021 Dec 27.
Beijing Key Laboratory of Environmental Toxicology, Capital Medical University, Beijing, 100069, PR China; Department of Toxicology and Sanitary Chemistry, School of Public Health, Capital Medical University, Beijing, 100069, PR China; Institute for Chemical Carcinogenesis, Guangzhou Medical University, Guangzhou, 511436, PR China. Electronic address:
Considerable investigations have been carried out to address the relationship between ambient fine particulate matter (PM) and blood pressure (BP) in patients with hypertension. However, few studies have explored the influence of PM and its constituents on Trimethylamine N-oxide (TMAO), an established risk factor for hypertension and cardiovascular disease (CVD), particularly in severely air-polluted areas. To explore the potential impact of PM constituents on BP, plasma hormones, and TMAO, a panel study was conducted to investigate changes in BP, plasma hormones, and TMAO in response to ambient air pollution exposure in stage 1 hypertensive young adults. Read More