314 results match your criteria ahead curve

Prediction of COVID-19 pervasiveness in six major affected states of India and two-stage variation with temperature.

Air Qual Atmos Health 2021 Sep 21:1-12. Epub 2021 Sep 21.

Department of Mathematics, Lovely Professional University, Punjab, 144411 India.

Coronavirus disease knocked in Wuhan city of China in December 2019 which spread quickly across the world and infected millions of people within a short span of time. COVID-19 is a fast-spreading contagious disease which is caused by SARS-CoV-2 (severe acute respiratory syndrome-coronavirus-2). Accurate time series forecasting modeling is the need of the hour to monitor and control the universality of COVID-19 effectively, which will help to take preventive measures to break the ongoing chain of infection. Read More

View Article and Full-Text PDF
September 2021

Ahead of the (ROC) Curve: A Statistical Approach to Utilizing Ex-Gaussian Parameters of Reaction Time in Diagnosing ADHD Across Three Developmental Periods.

J Int Neuropsychol Soc 2021 Sep 7:1-14. Epub 2021 Sep 7.

School of Kinesiology, Auburn University, Auburn, AL, USA.

Introduction: Performance on executive function (EF) tasks is only modestly predictive of a diagnosis of Attention Deficit Hyperactivity Disorder (ADHD), despite the common assumption that EF deficits are ubiquitous to the disorder. The current study sought to determine whether ex-Gaussian parameters of simple reaction time are better able to discriminate between children and adults with and without ADHD, compared with traditional measures of inhibitory control.

Methods: Receiver Operating Characteristic (ROC) analyses and the area under the curve (AUC) were used to examine the ability of performance on two commonly used tasks of inhibitory control (i. Read More

View Article and Full-Text PDF
September 2021

Simulating Study Design Choice Effects on Observed Performance of Predictive Patient Monitoring Alarm Algorithms.

IEEE EMBS Int Conf Biomed Health Inform 2021 Jul 10;2021. Epub 2021 Aug 10.

Center for Devices and Radiological Health, US FDA, Silver Spring, MD, USA.

There are multiple study design choices to be selected in order to perform evaluations of predictive patient monitoring algorithms related to the event and true positive alarm definitions (e.g., how far ahead of the event is a true positive alarm). Read More

View Article and Full-Text PDF


Transp Res E Logist Transp Rev 2021 Aug 19;152. Epub 2021 Jun 19.

Department of Civil and Environmental Engineering, University of Washington, Seattle, WA 98195 USA.

Timely and accurate forecast of evacuation demand is key for emergency responders to plan and organize effective evacuation efforts during a disaster. The state-of-the-art in evacuation demand forecasting includes behavior-based models and dynamic flow-based models. Both lines of work have critical limitations: behavioral models are static, meaning that they cannot adjust model predictions by utilizing field observation in real time as the disaster is unfolding; and the flow-based models often have relatively short prediction windows ranging from minutes to hours. Read More

View Article and Full-Text PDF

Predicting unsafe driving risk among commercial truck drivers using machine learning: Lessons learned from the surveillance of 20 million driving miles.

Accid Anal Prev 2021 Sep 10;159:106285. Epub 2021 Jul 10.

Farmer School of Business, Miami University, Oxford, OH 45056, USA. Electronic address:

The emergence of sensor-based Internet of Things (IoT) monitoring technologies have paved the way for conducting large-scale naturalistic driving studies, where continuous kinematic driver-based data are generated, capturing crash/near-crash safety critical events (SCEs) and their precursors. However, it is unknown whether the SCEs risk can be predicted to inform driver decisions in the medium term (e.g. Read More

View Article and Full-Text PDF
September 2021

Fine-scale changes in speed and altitude suggest protean movements in homing pigeon flights.

R Soc Open Sci 2021 May 19;8(5):210130. Epub 2021 May 19.

Biosciences, College of Science, Swansea University, Singleton Park, Swansea, UK.

The power curve provides a basis for predicting adjustments that animals make in flight speed, for example in relation to wind, distance, habitat foraging quality and objective. However, relatively few studies have examined how animals respond to the landscape below them, which could affect speed and power allocation through modifications in climb rate and perceived predation risk. We equipped homing pigeons () with high-frequency loggers to examine how flight speed, and hence effort, varies in relation to topography and land cover. Read More

View Article and Full-Text PDF

Characteristics of unilateral main bronchus obstruction and differentiation from chronic obstructive pulmonary disease by spirometry.

J Thorac Dis 2021 Apr;13(4):2264-2275

Department of Pulmonary and Critical Care Medicine, Peking University First Hospital, Beijing, China.

Background: Pattern of flow-volume (F-V) loop in unilateral main bronchus obstruction (UMBO) is under-represented and sometimes misinterpreted as chronic obstructive pulmonary disease (COPD).

Methods: A cross-sectional study was performed among patients with UMBO and COPD confirmed by bronchoscopy, radiographic imaging and spirometry from 2006 to 2019. Data were extracted from electronic medical records. Read More

View Article and Full-Text PDF

Early diagnosis of Alzheimer's disease on ADNI data using novel longitudinal score based on functional principal component analysis.

J Med Imaging (Bellingham) 2021 Mar 21;8(2):024502. Epub 2021 Apr 21.

Simon Fraser University, Department of Statistics and Actuarial Science, Burnaby, BC, Canada.

Alzheimer's disease (AD) is a worldwide prevalent age-related neurodegenerative disease with no available cure yet. Early prognosis is therefore crucial for planning proper clinical intervention. It is especially true for people diagnosed with mild cognitive impairment, to whom the prediction of whether and when the future disease onset would happen is particularly valuable. Read More

View Article and Full-Text PDF

Pandemics: Historically Slow "Learning Curve" Leading to Biomedical Informatics and Vaccine Breakthroughs.

Yearb Med Inform 2021 Aug 21;30(1):290-301. Epub 2021 Apr 21.

Department of Computer Science, Rutgers University, USA.

Background: The worldwide tragedy of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic vividly demonstrates just how inadequate mitigation and control of the spread of infectious diseases can be when faced with a new microorganism with unknown pathogenic effects. Responses by governments in charge of public health, and all other involved organizations, have proved largely wanting. Data infrastructure and the information and communication systems needed to deal with the pandemic have likewise not been up to the task. Read More

View Article and Full-Text PDF

Comparison of Predictive Models and Impact Assessment of Lockdown for COVID-19 over the United States.

J Epidemiol Glob Health 2021 06 22;11(2):200-207. Epub 2021 Feb 22.

Department of Mathematics, Southern Methodist University, Dallas, TX 75275, USA.

The novel Coronavirus Disease 2019 (COVID-19) remains a worldwide threat to community health, social stability, and economic development. Since the first case was recorded on December 29, 2019, in Wuhan of China, the disease has rapidly extended to other nations of the world to claim many lives, especially in the USA, the United Kingdom, and Western Europe. To stay ahead of the curve consequent of the continued increase in case and mortality, predictive tools are needed to guide adequate response. Read More

View Article and Full-Text PDF

Clinical Profile and Outcome of Patients with Cardiac Implantable Electronic Device-Related Infection.

Arq Bras Cardiol 2021 06;116(6):1080-1088

Universidade Federal de Minas Gerais - Departamento de Clínica Médica, Belo Horizonte, MG - Brasil.

Background: In recent years, the incidence of infections related to cardiac implantable electronic devices (CIED) has increased sharply, impacting mortality.

Objective: To verify the proportion of patients with CIED infection; to analyze their clinical profile and the variables related to the infection and its progression.

Methods: Retrospective and longitudinal observational study including 123 patients with CIED infection among 6406 procedures. Read More

View Article and Full-Text PDF

The significance of sense in the time of plagues: Curricular responsiveness to the Covid-19 crisis.

Hannah Spector

Prospects (Paris) 2021 Mar 29:1-17. Epub 2021 Mar 29.

Penn State Harrisburg, 777 W Harrisburg Pike, Middletown, PA 17057 USA.

The purpose of this article is to interrogate ways that curriculum can respond critically to already existing global emergencies (including pandemics) while also becoming more proactive toward the prevention of world risks. To do this, it calls for the fortification of the traditional course of study that introduces students to the analysis of literary texts. However, a traditional approach to school-based literary analysis that attends exclusively to a text's formal properties in order to determine its meaning is insufficient to get ahead of the world risk curve. Read More

View Article and Full-Text PDF

The Quixotic Task of Forecasting Peaks of COVID-19: Rather Focus on Forward and Backward Projections.

Front Public Health 2021 16;9:623521. Epub 2021 Mar 16.

Departamento de Ciência da Computação, Universidade Federal de Juiz de Fora, Juiz de Fora, Brazil.

Over the last months, mathematical models have been extensively used to help control the COVID-19 pandemic worldwide. Although extremely useful in many tasks, most models have performed poorly in forecasting the pandemic peaks. We investigate this common pitfall by forecasting four countries' pandemic peak: Austria, Germany, Italy, and South Korea. Read More

View Article and Full-Text PDF

Staying Ahead of the Epidemiologic Curve: Evaluation of the British Columbia Asthma Prediction System (BCAPS) During the Unprecedented 2018 Wildfire Season.

Front Public Health 2021 12;9:499309. Epub 2021 Mar 12.

Department of Epidemiology and Biostatistics, McGill University, Montreal, QC, Canada.

The modular British Columbia Asthma Prediction System (BCAPS) is designed to reduce information burden during wildfire smoke events by automatically gathering, integrating, generating, and visualizing data for public health users. The BCAPS framework comprises five flexible and geographically scalable modules: (1) historic data on fine particulate matter (PM) concentrations; (2) historic data on relevant health indicator counts; (3) PM forecasts for the upcoming days; (4) a health forecasting model that uses the relationship between (1) and (2) to predict the impacts of (3); and (5) a reporting mechanism. The 2018 wildfire season was the most extreme in British Columbia history. Read More

View Article and Full-Text PDF

Strategy to stay ahead of the curve: A concept analysis of talent management.

Nurs Forum 2021 Jul 26;56(3):717-723. Epub 2021 Mar 26.

College of Nursing, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.

Aim: The development of nurse leaders is critical to the future of the nursing profession. Strategies to address the current loss of nurse leaders are urgently needed. The aim of this analysis is to clarify the concept of talent management as an approach by which organizations can identify, strengthen, and support emerging and current nurse leaders. Read More

View Article and Full-Text PDF

Staying ahead of the curve: avigating changes and maintaining gains in patient safety culture - a mixed-methods study.

BMJ Open 2021 03 4;11(3):e044116. Epub 2021 Mar 4.

Health Management and Policy, American University of Beirut Faculty of Health Sciences, Beirut, Lebanon.

Objectives: This study examines how the results of the Hospital Survey on Patient Safety Culture changed between 2012 and 2019 and identifies organisational factors affecting these changes.

Design: The study combined the use of quantitative surveys of staff and qualitative interviews with hospital leadership. Secondary data analysis was performed for previous surveys. Read More

View Article and Full-Text PDF

Gensini Score and Thrombus Burden Add Predictive Value to the SYNTAX Score in Detecting No-Reflow after Myocardial Infarction.

Arq Bras Cardiol 2021 03;116(3):466-472

Universidade Estadual de Campinas,Campinas, SP - Brasil.

Background: No-reflow after percutaneous coronary intervention is associated with poor prognosis in patients with ST-segment elevation myocardial infarction (STEMI). SYNTAX score is a good predictor of no-reflow.

Objective: We aimed to evaluate whether atherosclerotic burden (Gensini score) and thrombus burden in the culprit coronary artery would improve the ability of the SYNTAX score to detect no-reflow. Read More

View Article and Full-Text PDF

Responding to COVID-19 Among U.S. Military Units in South Korea: The U.S. Forces Korea's Operation Kill the Virus.

Mil Med 2021 Feb 2. Epub 2021 Feb 2.

School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.

Introduction: The coronavirus disease 2019 (COVID-19) is a viral respiratory illness caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and has led to one of the world's largest infectious disease outbreaks. COVID-19 first emerged in Wuhan, Hubei, China, in December 2019, and the emergence was especially concerning to the U.S. Read More

View Article and Full-Text PDF
February 2021

COVID-19 and Myocardial Injury in a Brazilian ICU: High Incidence and Higher Risk of In-Hospital Mortality.

Arq Bras Cardiol 2021 Feb;116(2):275-282

Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ - Brasil.

Background: The incidence of myocardial injury (MI) in patients with COVID-19 in Brazil and the prognostic impact of MI have not been elucidated.

Objectives: To describe the incidence of MI in patients with COVID-19 in the intensive care unit (ICU) and to identify variables associated with its occurrence. The secondary objective was to assess high-sensitivity troponin I as a predictor of in-hospital mortality. Read More

View Article and Full-Text PDF
February 2021

Value of left atrial diameter with CHA2DS2-VASc score in predicting left atrial/left atrial appendage thrombosis in non-valvular atrial fibrillation.

Arq Bras Cardiol 2021 02;116(2):325-331

Cardiovascular Hospital of Zhengzhou, Zhengzhou - China.

Background: Atrial fibrillation is the most common persistent arrhythmia, and is the main factor that leads to thromboembolism.

Objective: To investigate the value of left atrial diameter combined with CHA2DS2-VASc score in predicting left atrial/left atrial appendage thrombosis in non-valvular atrial fibrillation.

Methods: This is a retrospective study. Read More

View Article and Full-Text PDF
February 2021

Impact of Demographic, Clinical and Psychosocial Variables on Drug Adherence and Outcomes in Indian Patients With Inflammatory Bowel Disease: Cost is not the Only Factor!

J Clin Gastroenterol 2021 Jan 5;Publish Ahead of Print. Epub 2021 Jan 5.

Department of Medical Gastroenterology, Asian Institute of Gastroenterology, Hyderabad, Telangana, India.

Background And Aims: Barriers to drug adherence in the developing world are multifactorial and under evaluated. We aimed to evaluate predictive factors of medication adherence in Indian patients with inflammatory bowel disease (IBD) and association of adherence with quality of life (QOL) and relapse free remission.

Materials And Methods: Adherence was assessed in consecutive IBD patients using a self-administered survey questionnaire including Morisky Medication Adherence Scale together with interview and Short Inflammatory Bowel Disease Questionnaire (SIBDQ) to assess QOL. Read More

View Article and Full-Text PDF
January 2021

The age, bilirubin and albumin (ABA) index: a novel noninvasive index for predicting liver fibrosis in patients with chronic hepatitis C infection.

Eur J Gastroenterol Hepatol 2021 Jan 6;Publish Ahead of Print. Epub 2021 Jan 6.

Department of Gastroenterology, Biruni University School of Medicine, İstanbul Department of Gastroenterology, Hitit University School of Medicine, Corum Department of Medical Biochemistry, Eskisehir Osmangazi University School of Medicine, Eskisehir Department of Medical Biochemistry, Hitit University School of Medicine, Corum Department of Gastroenterology, Tokat Gaziosmanpasa University School of Medicine, Tokat Clinic of Gastroenterology, Diskapi Yildirim Beyazit Education and Research Hospital, Ankara, Turkey.

Aim: It was to assess the diagnostic performance characteristics of a novel index, (ABA), which utilizes age, bilirubin and albumin to predict significant and severe fibrosis, and cirrhosis in patients with chronic hepatitis C infection.

Methods: A total of 114 patients were included in this study. The liver biopsies were graded using the Ishak scoring system. Read More

View Article and Full-Text PDF
January 2021

Aminotransferase-to-platelet ratio index and Fibrosis-4 index score predict hepatic fibrosis evaluated by transient hepatic elastography in hepatitis C virus-infected hemodialysis patients.

Eur J Gastroenterol Hepatol 2021 Jan 6;Publish Ahead of Print. Epub 2021 Jan 6.

Nephrology Department, Clementino Fraga Filho University Hospital, Federal University of Rio de Janeiro Hepatology Department, Clementino Fraga Filho University Hospital, Federal University of Rio de Janeiro Internal Medicine Department, Federal University of Rio de Janeiro D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Brazil.

Objective: This study aimed to evaluate the performance of aminotransferase-to-platelet ratio index (APRI) and Fibrosis-4 index (FIB-4) in chronic kidney disease stage 5D HCV-infected patients compared to transient hepatic elastography (TE) as the gold standard.

Methods: Hemodialysis HCV-infected patients submitted to TE (FibroScan, Echosens, Paris, France) had APRI and FIB-4 calculated. Based on the best area under receiver operating characteristic curve (AUROC) for significant fibrosis and cirrhosis, APRI and FIB-4 cutoffs were determined and their performances were compared. Read More

View Article and Full-Text PDF
January 2021

Prognostic significance of inflammation-based score in patients with hepatocellular carcinoma after liver transplantation.

Eur J Gastroenterol Hepatol 2021 Jan 6;Publish Ahead of Print. Epub 2021 Jan 6.

Department of Emergency Surgery Department of Emergency Medicine Department of Ultrasound, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou Department of Infectious Diseases, the First Affiliated Hospital of Anhui Medical University Anhui Center for Surveillance of Bacterial Resistance, Hefei Department of Liver Transplantation, China.

Background: Recent studies have revealed that combining of the platelet to lymphocyte ratio (PLR) and the neutrophil to lymphocyte ratio (NLR) [(combination of neutrophil-lymphocyte ratio and platelet-lymphocyte ratio (CNP)] links with dismal prognosis in diverse cancers. Here, we elucidated the prognostic significance of CNP, acting as a novel inflammation-based score, for predicting the survival of hepatocellular carcinoma (HCC) patients following liver transplantation.

Method: We retrospectively recruited 100 patients with HCC who met the Hangzhou criteria for liver transplantation. Read More

View Article and Full-Text PDF
January 2021

Pioneering groundwater contamination investigation, research, and in situ treatment.

David A Dzombak

Water Environ Res 2021 Aug 24;93(8):O1-O10. Epub 2021 Jan 24.

Department of Civil and Environmental Engineering, Carnegie Mellon University, Pittsburgh, PA, USA.

The 1972 paper by Professor Jack McKee of the California Institute of Technology, consulting engineer Finley Laverty and Raymond Hertzel of the California Regional Water Quality Control Board-Los Angeles (McKee et al., 1972) was an early, important contribution to the understanding of groundwater contamination with organic liquids and to the integrated use of field, laboratory, and modeling studies to develop remediation approaches. The work presented in the paper was ahead of the curve and helped provide the foundation for the intense research, development, and education in investigation and remediation of groundwater contamination problems that began around 1980 and lasted for two decades. Read More

View Article and Full-Text PDF

A logistic model and predictions for the spread of the COVID-19 pandemic.

Chaos 2020 Dec;30(12):123135

Los Alamos National Laboratory, Los Alamos, New Mexico 87545, USA.

The rapid spread of COVID-19 worldwide presents a great challenge to epidemic modelers. Model outcomes vary widely depending on the characteristics of a pathogen and the models. Here, we present a logistic model for the epidemic spread and divide the spread of the novel coronavirus into two phases: the first phase is a natural exponential growth phase that occurs in the absence of intervention and the second phase is a regulated growth phase that is affected by enforcing social distancing and isolation. Read More

View Article and Full-Text PDF
December 2020

Early Left Ventricular Diastolic Dysfunction and Abnormal Left Ventricular-left Atrial Coupling in Asymptomatic Patients With Hypertension: A Cardiovascular Magnetic Resonance Feature Tracking Study.

J Thorac Imaging 2020 Dec 24;Publish Ahead of Print. Epub 2020 Dec 24.

Department of Magnetic Resonance Imaging, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing Department of Magnetic Resonance Imaging, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

Purpose: Hypertension (HTN) patients suffer from increased risk of left ventricular (LV) diastolic dysfunction and LV hypertrophy (LVH). Evaluation of early LV diastolic function requires accurate noninvasive diagnostic tools. The aim of this study was to evaluate whether cardiovascular magnetic resonance feature-tracking (CMR-FT) could detect early LV dysfunction and evaluate LV-left atrium (LA) correlation in HTN patients. Read More

View Article and Full-Text PDF
December 2020

Correlation Between Invasive and Noninvasive Technique of Intracranial Pressure Measurement in Children With Traumatic Brain Injury: An Observational Study.

J Neurosurg Anesthesiol 2020 Dec 18;Publish Ahead of Print. Epub 2020 Dec 18.

Department of Neuroanesthesiology and Critical Care, All India Institute of Medical Sciences, New Delhi, Delhi, India.

Background: Direct measurement of intracranial pressure (ICP) is an invasive technique with potential complications, which has prompted the development of alternative, noninvasive, methods of ICP assessment. The aim of this study was to determine the relationship between noninvasive ultrasound-based measurement of optic nerve sheath diameter (ONSD), transcranial Doppler-derived pulsatility index (PI), and invasive ICP measurements in children with traumatic brain injury (TBI).

Methods: Children aged 1 to 18 years undergoing invasive ICP monitoring following TBI were included in the study. Read More

View Article and Full-Text PDF
December 2020

Increasing Financial Empowerment among Survivors of Intimate Partner Violence: A Growth Curve Analysis.

Laura Johnson

Am J Community Psychol 2021 09 18;68(1-2):29-46. Epub 2020 Dec 18.

School of Social Work, Temple University, Philadelphia, PA, USA.

Financial empowerment interventions are often used with survivors of intimate partner violence (IPV) to improve their financial well-being. However, few evaluations actually measure financial empowerment as an outcome. Thus, the purpose of this study was to develop and test a conceptual model for financial empowerment and then use the model to evaluate the effectiveness of a financial literacy intervention at increasing financial empowerment for survivors. Read More

View Article and Full-Text PDF
September 2021

The Referential Montage Inadequately Localizes Corticocortical Evoked Potentials in Stereoelectroencephalography.

J Clin Neurophysiol 2020 Dec 15;Publish Ahead of Print. Epub 2020 Dec 15.

Department of Neurology, Emory University and Emory Epilepsy Center, Atlanta, Georgia, U.S.A.; Departments of Pediatrics and Neurology. Atlanta, Georgia, U.S.A. Department of Neurosurgery, Emory University, Atlanta, Georgia, U.S.A.; and Emory Neuromodulation Technology Innovation Center, Emory University and Georgia Institute of Technology, Atlanta, Georgia, U.S.A.

Purpose: Corticocortical evoked potentials (CCEPs) resulting from single pulse electrical stimulation are increasingly used to understand seizure networks, as well as normal brain connectivity. However, we observed that when using depth electrodes, traditional measures of CCEPs amplitude using a referential montage can be falsely localizing, often to white matter.

Methods: We pooled 27 linear electrode arrays targeting the amygdala, hippocampus, or cingulate cortex from eight participants. Read More

View Article and Full-Text PDF
December 2020