J Am Psychiatr Nurses Assoc 2021 Jul 8:10783903211030343. Epub 2021 Jul 8.
Tarah Winter Klinefelter, MSN, APRN, PMHNP-BC, Psychiatric Mental Health Nurse Practitioner in Geriatric Psychiatry, El Paso, TX, USA.
Objective: While dysfunction of serotonin and dopamine neurotransmitters has been studied in depth, in regard to the etiology of mental illness, the neurotransmitter glutamate and its dysfunction is now being explored as contributing to neurodegenerative psychiatric diseases, schizophrenia, autism, depression, and Alzheimer's disease. This article explains its synthesis, neurotransmission, and metabolism within the brain and subsequent dysfunction that is responsible for neurocognitive loss associated with several psychiatric disorders.
Method: The case study will report on the screening for pseudobulbar affective (PBA) disorder in a 29-year-old male with bipolar disorder, autism spectrum disorder, and intellectual developmental disability who was experiencing extreme, uncontrolled emotional outbursts requiring continuous family isolation (pre-COVID-19) for safety. Read More