J Microencapsul 2021 May 5:1-14. Epub 2021 May 5.
Department of Biology, Faculty of Biological Science, North Tehran Branch, Islamic Azad University, Tehran, Iran.
Synthesis and investigation of biological activity of smoke-loaded poly(lactic-co-glycolic acid) (PLGA) nanoparticles. smoke-loaded PLGA nanoparticles (PHSE-PNP) were produced by double emulsion solvent evaporation method and characterised by scanning electron microscopy (SEM), dynamic light scattering (DLS), and -potential. 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) for toxicity evaluation, 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), 2,2-diphenyl-1-picrylhydrazyl (DPPH), and ferric reducing antioxidant power (FRAP) assay for antioxidant power, chorioallantoic membrane (CAM), qPCR, and scratch assay for angiogenesis and mouse cancer model for antitumor effects of PHSE-PNP's were used. Read More