Search Our Scientific Publications & Authors

Am Surg 2021 Apr 20:31348211011139. Epub 2021 Apr 20.

Department of General Surgery, 9978Queen's University, Kingston, Canada.

Background: Intussusception is the most common cause of bowel obstruction in children aged 3 months to 6 years of age. We sought to describe patterns of incident childhood intussusception.

Methods: A retrospective longitudinal cohort study utilizing population-based health administrative data and a validated case definition was used to identify patients <18 years of age treated for intussusception between January 1, 1997 and December 31, 2016 in Ontario, Canada. Read More

Front Pediatr 2021 31;9:651297. Epub 2021 Mar 31.

Department of Surgery, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, South Korea.

The purpose of this study was to evaluate whether clinical findings in children with ileocolic intussusception differ based on age and duration of symptoms and to assess the clinical characteristics of diagnosed and undiagnosed patients to determine which symptoms make diagnosis more difficult. We reviewed 536 medical records of <15-year-old children diagnosed with ileocolic intussusception between 2008 and 2019. We divided the children into three categories according to age (<1 year, 1-2 years, and ≥2 years). Read More

J Infect Chemother 2021 Apr 15. Epub 2021 Apr 15.

Department of Pediatrics, Sapporo Medical University School of Medicine, Sapporo, 060-8543, Japan.

In Japan, a monovalent rotavirus vaccine (RV1) and a pentavalent rotavirus vaccine (RV5) were launched as voluntary vaccinations in November 2011 and July 2012, respectively. Rotavirus (RV) vaccine coverage in Japan increased from 30.0% in 2012 to 78. Read More

Wiad Lek 2021 ;74(2):179-183

VINNITSYA MEMORIAL PYROGOV NATIONAL MEDICAL UNIVERSITY, VINNYTSIA, UKRAINE.

Objective: The aim: To clarify the sources and determine the chronological sequence of the germs of anatomical structures of the orbit at the early period of human ontogenesis.

Patients And Methods: Materials and methods: Using a complex of methods of morphological examination (morphometry, microscopy, three-dimensional computer reconstruction and statistical analysis) 30 series of consecutive histological sections of human embryos and prefetuses aged from 3 till 8 weeks od IUD (3.0-30. Read More

BMJ Case Rep 2021 Feb 9;14(2). Epub 2021 Feb 9.

The Division of Interventional Radiology, Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins Hospital, Baltimore, Maryland, USA.

Percutaneous cholecystostomy (PC) is a common minimally invasive, image-guided procedure performed primarily on high-risk patients with acute cholecystitis for gallbladder decompression. Herein, we present a case of a patient undergoing PC placement using a transperitoneal approach. On subsequent upsizing attempts, the gallbladder fundus was found to invaginate during advancement of replacement drains, causing gallbladder intussusception. Read More

Gan To Kagaku Ryoho 2020 Dec;47(13):1866-1868

Dept. of Surgery, Houju Memorial Hospital.

A 55-year-old man complaining of difficulty in defecation was referred to our hospital. A digital examination and abdominal CT led to a diagnosis of intussusception due to tumor of the sigmoid colon. The intussusception was successful reduced by enema. Read More

Gan To Kagaku Ryoho 2021 Jan;48(1):89-91

Dept. of Surgery, Japanese Red Cross Wakayama Medical Center.

A 77-year-old woman, who underwent surgery for malignant melanoma of the nasal cavity 15 months prior and radiation and interferon-β therapy for local recurrence, presented with epigastric discomfort. PET-CT examination showed multiple intussusceptions due to small intestinal tumors. Four intussusceptions were detected during laparotomy, and she underwent partial resection of the small intestine. Read More

Vaccine 2021 Feb 16;39(7):1140-1147. Epub 2021 Jan 16.

Department of Epidemiology, Vietnam Military Medical University, Viet Nam; Department of Training, Vietnam Military Medical University, Viet Nam. Electronic address:

Background: ROTAVAC® is derived from human 116E rotavirus (RV) neonatal strain. In this study, we evaluated the immunogenicity, safety and reactogenicity of ROTAVAC® in Vietnam.

Method: We conducted a phase IV clinical trial in healthy infants aged 6-8 weeks using the complete regimen of ROTAVAC® with three doses. Read More

World J Emerg Surg 2021 Jan 13;16(1). Epub 2021 Jan 13.

Department of Pediatric Surgery, Shengjing Hospital, China Medical University, No. 36 Sanhao Street, Heping District, Shenyang, 110004, P. R. China.

Background: Intussusception is the most common abdominal emergency in children. The first line treatment of uncomplicated pediatric intussusception is enema reduction. Until now, there have been no multi-center studies comparing the effectiveness and safety of UGHR and FGAR in the treatment of pediatric intussusception. Read More

Indian J Pediatr 2021 Mar 6;88(Suppl 1):131-137. Epub 2021 Jan 6.

Christian Medical College, Vellore, Tamil Nadu, India.

Objective: To determine the clinical and epidemiological profile of Intussusception in children aged <2 y after introduction of rotavirus vaccine in Universal Immunization Programme of Rajasthan.

Method: This was a hospital-based multi-centric surveillance study conducted at three tertiary care sentinel sites in Rajasthan over a period of 2 y. Children <2 y of age admitted with intussusception as per Brighton's criteria 1 were enrolled. Read More

J Med Ultrason (2001) 2021 Jan 2;48(1):21-29. Epub 2021 Jan 2.

Department of Radiology, Saitama Children's Medical Center, 1-2 Shintoshin, Chuo-ku, Saitama, Saitama, 330-8777, Japan.

Choledochal cyst, which is a congenital dilatation of the bile duct, is a common congenital disease requiring surgical repair. This disease usually occurs in children aged < 10 years, necessitating a relatively long follow-up after repair. The incidence of this congenital disease in Asian countries, including Japan, was reported to be higher than that in other countries. Read More

J Obstet Gynaecol Can 2021 Apr 13;43(4):440-446. Epub 2021 Feb 13.

Department of Obstetrics and Gynecology, McGill University, Montréal, QC.

Objective: To evaluate the association between endometriosis and bowel obstruction or intussusception using a large population database.

Methods: This was a population-based study using data from the Healthcare Cost and Utilization Project-Nationwide Inpatient Sample (HCUP-NIS) from 2005 to 2014. We studied women aged 18 to 55 years without inflammatory bowel disease or cancer. Read More

Tokai J Exp Clin Med 2020 Dec 20;45(4):202-206. Epub 2020 Dec 20.

Department of gastroenterological surgery, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa 259-1193, Japan.

Introduction: Intussusception occurs when one part of the intestines slides into the adjacent intestine resulting in bowel obstruction. It is a rare condition in adults, accounting for only 5% of all intussusceptions. It has multiple causes, with inflammatory fibroid polyps (IFPs) very infrequently being the cause. Read More

Vaccine 2021 01 29;39(4):746-750. Epub 2020 Nov 29.

Viral Gastroenteritis Branch, Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention USA.

Introduction: In 2006 and 2008, two live, oral rotavirus vaccines, RotaTeq (RV5) and Rotarix (RV1), were introduced into the routine immunization program in the United States. A previous rotavirus vaccine, RotaShield, was associated with an increased risk of intussusception, with data suggesting an age-dependent variation in risk. Advisory Committee on Immunization Practices (ACIP) currently recommends that RV5 or RV1 immunization be initiated by age 14 weeks and 6 days and completed by 8 months 0 days. Read More

Rev Esp Enferm Dig 2020 Dec;112(12):950-951

Radiology, Hospital Beatriz Ângelo , Portugal.

Waugh's syndrome is the association of intussusception and intestinal malrotation, almost always reported in the pediatric population. We present images of a middle-aged adult with a large ileocolic intussusception in association with intestinal malrotation, the latter was concluded to be the underlying cause. Read More

J Pak Med Assoc 2020 Oct;70(10):1727-1730

Department of Pediatric Surgery, Weifang Peoples Hospital, Weifang City, Shandong Province, China.

Objective: To investigate the clinical characteristics of early recurrent intussusception after ultrasound-guided saline reduction, and to explore the factors leading to early recurrence.

Methods: The retrospective observational case-control study was conducted at Weifang People's Hospital, Shandong, China, and comprised data from January 2015 to December 2017 related to paediatric intussusception patients aged 0-12 years who underwent ultrasound-guided saline enema reduction. The patients were divided into two recurrent and non-recurrent groups. Read More

PLoS One 2020 5;15(11):e0241337. Epub 2020 Nov 5.

Division of Gastroenterology and Hepatology, Department of Internal Medicine, The Jikei University Kashiwa Hospital, Kashiwa, Chiba, Japan.

Introduction: Indigo naturalis (IN) is a blue pigment extracted from Assam indigo and other plants and has been confirmed to be highly effective for ulcerative colitis (UC) treatment in several clinical studies.

Objective: We conducted a multicenter double-blind study to confirm the efficacy and safety of short-term IN administration.

Methods: A multicenter, randomized controlled trial was conducted between December 2015 and October 2018 in our facilities. Read More

Int J Mol Sci 2020 Oct 28;21(21). Epub 2020 Oct 28.

Department of Cell Biology and Histology, School of Medicine, Campus of International Excellence "Campus Mare Nostrum", IMIB-Arrixaca, University of Murcia, 30100 Murcia, Spain.

Angiogenesis in arterial intimal thickening (AIT) has been considered mainly in late AIT stages and only refers to sprouting angiogenesis. We assess angiogenesis during early AIT development and the occurrence of the intussusceptive type. For this purpose, we studied AIT development in (a) human arteries with vasculitis in gallbladders with acute cholecystitis and urgent ( = 25) or delayed ( = 20) cholecystectomy, using immunohistochemical techniques and (b) experimentally occluded arterial segments ( = 56), using semithin and ultrathin sections and electron microscopy. Read More

J Radiol Case Rep 2020 Jun 30;14(6):8-14. Epub 2020 Jun 30.

Department of Radiology, Aventura Hospital and Medical Center, Aventura, Fl, USA.

Appendiceal intussusception is rare with an estimated incidence of 0.01%. Although it is infrequently encountered, the few documented cases of this entity have shown it may mimic or indicate an underlying neoplasm when evaluated with colonoscopy. Read More

Vaccine 2021 01 21;39(1):78-84. Epub 2020 Sep 21.

Background: An association between rotavirus vaccination and intussusception has been documented in post-licensure studies in some countries. We evaluated the risk of intussusception associated with monovalent rotavirus vaccine (Rotavac) administered at 6, 10 and 14 weeks of age in India.

Methods: Active prospective surveillance for intussusception was conducted at 22 hospitals across 16 states from April 2016 through September 2017. Read More

Pan Afr Med J 2020 21;36:200. Epub 2020 Jul 21.

Department of General Surgery, Trauma and Burns Center, Ben Arous, Tunisia.

Colo-rectal intussusception is rare in adults and is often secondary to malignant lesions, rarely benign lesions such as colonic lipomas can also be the cause. We present the case a 60-year-old man who presented to the emergency department with acute abdominal pain. On physical examination, the abdomen was distended with diffuse tenderness. Read More

Medicine (Baltimore) 2020 Sep;99(36):e22080

Bariatric and Metabolism International Surgery Center.

Rationale: Intussusception is defined as the invagination or telescoping of a proximal portion of the intestine into the distal portion of the intestine. Intussusception can occur at any age but is more common among children. Most cases of intussusception in adults have a pathological lead point. Read More

BMC Pediatr 2020 09 1;20(1):413. Epub 2020 Sep 1.

Background: India introduced rotavirus vaccines (RVV, monovalent, Rotavac™ and pentavalent, Rotasiil™) in April 2016 with 6, 10 and 14 weeks schedule and expanded countrywide in phases. We describe the epidemiology of intussusception among children aged 2-23 months in India.

Methods: The prospective surveillance at 19 nationally representative sentinel hospitals from four regions recruited children with intussusception from April 2016 to September 2017. Read More

Sci Rep 2020 08 24;10(1):14122. Epub 2020 Aug 24.

Section of Pharmacology, Department of Diagnostics and Public Health, University of Verona, Verona, Italy.

Reporting and analysis of Adverse Events Following Immunization (AEFIs) are the cornerstones of vaccine safety surveillance prompting causality assessment and signal detection. This paper describes the impact of the Italian Pharmacovigilance System of vaccines over a 10-year period (2008-2017). The reporting rate (RR) per all distributed dose was calculated. Read More

J Gastrointestin Liver Dis 2020 Sep 9;29(3):455-460. Epub 2020 Sep 9.

Department of Gastroenterology, Clinical Hospital Centre Rijeka, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.

Aim: Starting from a case presentation, this review aims to present literature data on inflammatory fibroid polyps (IFPs) of the small intestine.

Methods: Case report and systematic review. A comprehensive systematic review of English literature using PubMed was conducted, based on Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Read More

Eur J Pediatr 2021 Feb 18;180(2):407-413. Epub 2020 Aug 18.

Department of Pediatric and Adolescent Surgery, Schneider Children's Medical Center of Israel affiliated with Sackler Faculty of Medicine, Tel Aviv University, Kaplan St 14, 4920235, Petah Tikva, Israel.

Acute appendicitis is the most common cause of acute abdominal pathology in children. However, other rare non-inflammatory non-neoplastic disorders involving the appendix may manifest as surgical emergencies. This study aimed to describe these atypical entities and present representative cases. Read More

Vaccine 2020 09 28;38(40):6299-6303. Epub 2020 Jul 28.

Health Data Research Center, National Taiwan University, Taipei, Taiwan.

Background: Since 2006, two rotavirus vaccines have been licensed in Taiwan, either as a 2- (RV1) or 3-dose (RV5) schedule administered at ages 2, 4, and 6 months. This study assessed the risk of intussusception and Kawasaki disease (KD) associated with rotavirus vaccines among infants.

Methods: Cases of intussusception and KD in infants aged less than 365 days were identified from the National Health Insurance databases, from 1 January 2007 through 31 December 2014, using the first-ever ICD-9-CM diagnosis codes. Read More

Am J Case Rep 2020 Jul 30;21:e922855. Epub 2020 Jul 30.

Digestive Endoscopy Unit, Gaetano Fucito Hospital, Mercato San Severino, Italy.

BACKGROUND Endoscopic full-thickness resection represents an innovative procedure, used in selected patients that allows lesions en-bloc resection with an integral wall specimen available for histopathological definition. Bleeding and perforation are known to be the most frequent procedure-related adverse events. We report a case of entero-colonic fistula as complication of an endoscopic full-thickness resection. Read More

Oxf Med Case Reports 2020 Jul 24;2020(7):omaa050. Epub 2020 Jul 24.

Department of Surgery, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia.

Intestinal obstruction is a common surgical emergency requiring urgent intervention. Small bowel obstruction secondary to intussusception is rarely encountered especially when inflammatory fibroid polyp (IFP) is the lead point. A 41-year-old gentleman with intestinal intussusception secondary to IFP presented to us with a classic symptom of intestinal obstruction. Read More

J Pediatr Surg 2020 Jun 23. Epub 2020 Jun 23.

Department of Ultrasound Diagnostics, Changsha Central Hospital, Nanhua University, 161 Shaoshan South Road, Yuhua District, Changsha, Hunan 410004, P.R. China. Electronic address:

Purpose: The clinical treatment of ileocolic intussusception is different from that of small-bowel intussusception (SBI). This study aimed to analyze the differences between the two groups using ultrasonoscopy to avoid misdiagnosis.

Methods: We conducted a retrospective study of intussusception in patients aged 0-18 years from September 2018 to March 2020. Read More