168,235 results match your criteria aged eye


Sexual orientation and functional limitations: Cross-sectional analyses from the Adult Psychiatric Morbidity Survey.

Arch Phys Med Rehabil 2021 May 4. Epub 2021 May 4.

The Cambridge Centre for Sport and Exercise Sciences, Anglia Ruskin University, Cambridge, UK.

Objective: To assess the association between sexual orientation and functional limitations in a large representative sample of the English population.

Design: Cross-sectional.

Setting: Data were from the 2007 Adult Psychiatric Morbidity Survey (APMS). Read More

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Effect of gestational age at birth, sex, and race on foveal structure in children.

Graefes Arch Clin Exp Ophthalmol 2021 May 7. Epub 2021 May 7.

Department of Biological and Vision Sciences, State University of New York College of Optometry, New York, NY, USA.

Purpose: Premature birth, race, and sex are contributing risk factors for retinopathy of prematurity (ROP) and have long-term impact on children's retinal structure. Few studies investigate impact of race and sex on macular structure in children born preterm. This study compared foveal structure in preterm and full-term children. Read More

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Development of angle closure and associated risk factors: The Handan eye study.

Acta Ophthalmol 2021 May 7. Epub 2021 May 7.

Beijing Tongren Eye Center, Beijing Key Laboratory of Ophthalmology and Visual Science, Beijing Tongren Hospital, Capital Medical University, Beijing, China.

Purpose: To investigate the development of angle closure from baseline open angle and associated risk factors in a rural Chinese population through a longitudinal study over a 5-year period.

Methods: Subjects aged ≥30 years and older with bilateral open angles at baseline of the Handan Eye Study who participated in the follow-up and had undergone both baseline and follow-up gonioscopic examinations were included. Subjects with any form of angle closure, glaucoma, incisional ocular surgery or other conditions that could influence the results were excluded. Read More

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Ocular biometry in children and adolescents from 4 to 17 years: a cross-sectional study in central Germany.

Ophthalmic Physiol Opt 2021 May;41(3):496-511

Institute for Medical Informatics, Statistics, and Epidemiology (IMISE), Leipzig University, Leipzig, Germany.

Purpose: To evaluate ocular biometry in a large paediatric population as a function of age and sex in children of European descent.

Methods: Children were examined as part of the LIFE Child Study (Leipzig Research Centre for Civilization Disease), a population-based study in Leipzig, Germany. Altogether, 1907 children, aged from 4 to 17 years, were examined with the Lenstar LS 900. Read More

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Newer insights into the clinical profile of posterior lenticonus in children and its surgical, visual, refractive outcomes.

Eye (Lond) 2021 May 6. Epub 2021 May 6.

Child Sight Institute, Jasti V Ramanamma Children's Eye Care Centre, L V Prasad Eye Institute, Hyderabad, India.

Purpose: To analyze the clinical profile of patients with posterior lenticonus and their surgical, visual, and refractive outcomes.

Results: Retrospective interventional case series of 84 eyes of 63 patients with posterior lenticonus. The incidence of posterior lenticonus was 3. Read More

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Improving health-related quality of life in glaucoma during 11 years and its association with vision loss and treatment of the disease.

Acta Ophthalmol 2021 May 6. Epub 2021 May 6.

Department of Ophthalmology, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.

Purpose: To evaluate the impact of glaucoma on health-related quality of life (HRQoL) and mental health in the ageing population of Finland.

Methods: Altogether 7380 and 5774 Finnish individuals aged 30 years and older with known eye disease status were studied in 2000 and 2011, respectively, in two population-based surveys, including an 11-year follow-up of 4683 participants. Data on HRQoL (EQ-5D-3L, 15D), depression (BDI), psychological distress (GHQ-12) and eye disease diagnoses were obtained from self-reported assessments. Read More

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Determinants of peripapillary retinal nerve fiber layer's grayscale value in normal eyes by spectral domain optical coherence tomography.

Sci Rep 2021 May 5;11(1):9577. Epub 2021 May 5.

Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong, Shantou University Medical College, Shantou, 515000, Guangdong, China.

To determine and evaluate the distribution, variation, and determinants of peripapillary retinal nerve fiber layer (pRNFL) grayscale value with spectral-domain optical coherence tomography (SD-OCT) in normal eyes. In this cross-sectional study, three hundred ninety-seven normal eyes from 397 healthy Chinese adults aged 18-80 were consecutively recruited from a tertiary eye care center. An SD-OCT instrument took pRNFL imaging. Read More

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Correlation of iCare ic100 tonometry with iCare TA01i in screening of unselected population in Northern Finland Birth Cohort Eye study.

Eur J Ophthalmol 2021 May 5:11206721211014387. Epub 2021 May 5.

Department of Ophthalmology, Oulu University Hospital, Oulu, Finland.

Purpose: iCare tonometers are easy-to-use and portable devices for measuring the intraocular pressure (IOP). Purpose was to evaluate the IOP values measured by both novel iCare ic100 and conventional model TA01i devices in unselected population.

Methods: IOP was measured with iCare ic100 and TA01i tonometers in 149 participants aged 32-33 years (born in 1985 or 1986) of the Northern Finland Birth Cohort Eye 2 study. Read More

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Comparison of Quality of Life Questionnaires in Patients with Low Vision

Turk J Ophthalmol 2021 04;51(2):83-88

Ankara University Faculty of Medicine, Department of Ophthalmology, Ankara, Turkey

Objectives: To compare the quality of life assessed by the Low Vision Quality of Life Questionnaire (LVQOL) and National Eye Institute Visual Function Questionnaire (NEI VFQ-25) in patients with low vision.

Materials And Methods: A total of 64 consecutive patients who presented to the Ankara University Low Vision Rehabilitation Department for the first time were included in the study. Patients aged 18 or older who had a best-corrected visual acuity of less than 20/60 or a visual field of equal to or less than 20° from the fixation point in the better eye were included. Read More

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Myelinated Retinal Nerve Fiber Progression in a 10-Year Follow-Up. The Beijing Eye Study 2001/2011.

Am J Ophthalmol 2021 May 2. Epub 2021 May 2.

Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Sciences Key Laboratory, Beijing, China; Department of Ophthalmology, Medical Faculty Mannheim of the Ruprecht-Karls-University Heidelberg, Mannheim, Germany; Institute of Clinical and Scientific Ophthalmology and Acupuncture Jonas & Panda, Heidelberg, Germany; Institute of Molecular and Clinical Ophthalmology Basel, Switzerland.

Purpose: To assess the prevalence of myelinated retinal nerve fibers (MRNFs), the rate of their change in a 10-year follow-up, and associations with ocular and systematic parameters in a population-based cohort.

Design: Longitudinal population-based cohort study.

Methods: The Beijing Eye study including 4439 participants aged 40+ years in 2001 and was repeated in 2011, with 2695 individuals (66. Read More

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The performance of an integrated model including retinal information in predicting childhood hypertension.

Pediatr Res 2021 May 4. Epub 2021 May 4.

Beijing Tongren Eye Center, Beijing Tongren Hospital, Beijing Ophthalmology and Visual Sciences Key Laboratory, Capital Medical University, Beijing, China.

Background: The objective of this study was to examine the association of an integrated model (composed of retinal arteriolar caliber, height, and sex) with blood pressure (BP) among a group of Chinese children, and assess the predictive value of the integrated model for childhood hypertension.

Methods: This study included 1460 candidates aged 12.634 ± 0. Read More

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Surgical outcomes with high and low pulse energy femtosecond laser systems for cataract surgery.

Sci Rep 2021 May 4;11(1):9525. Epub 2021 May 4.

Universal Eye Center, Taipei, Taiwan, Republic of China.

Currently, there is no clear consensus in cataract surgery if low compared to high energy femto-lasers may enable better capsulotomy quality and induce lower inflammatory response. Therefore, the aim of this study was to compare the intra-operative outcomes achieved with high and low pulse energy femtosecond laser systems for cataract surgery. The charts of 200 eyes of 200 patients aged 68. Read More

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A Systematic Review of the Proportion of Blindness in the Population 50 Years and Older from Total Population-Based Surveys of Blindness and Visual Impairment.

Ophthalmic Epidemiol 2021 May 4:1-7. Epub 2021 May 4.

Clinical Research Department, International Centre for Eye Health, London School of Hygiene and Tropical Medicine, London, UK.

Epidemiological data is essential for planning; however, all-age population-based surveys are resource intensive. Rapid Assessment of Cataract Surgical Services methodology was developed in India in 1995 and subsequently promoted by the World Health Organisation for use worldwide. The commonly used Rapid Assessment of Avoidable Blindness (RAAB) evolved from this in 2005, constraining surveys to populations aged 50 or more based on the report 'The Epidemiology of Blindness in Nepal' (SEVA, 1988), where 78. Read More

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Parsplana vitrectomy alone versus parsplana vitrectomy combined with phacoemulsification for the treatment of rhegmatogenous retinal detachment: a randomized study.

BMC Ophthalmol 2021 May 3;21(1):196. Epub 2021 May 3.

Ophthalmology Unit, Department of Medicine and Surgery, University Hospital of Parma, via Gramsci 14, 43126, Parma, Italy.

Background: To compare parsplana vitrectomy (PPV) with and without phacoemulsification to treat rhegmatogenous retinal detachment (RRD).

Methods: Subjects aged 48-65 years with RRD in a phakic eye due to superior retinal tears with an overall extension of retinal breaks < 90° underwent to PPV alone (group A); or PPV plus phacoemulsification (phacovitrectomy, PCV, group B). Post-operative follow-up visits occurred at 1 week, 1 month (m1), 3 months (m3), and 6 months (m6) after surgery. Read More

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Incidence, individual, and macro level risk factors of severe binocular visual impairment and blindness in persons aged 50 and older.

PLoS One 2021 3;16(5):e0251018. Epub 2021 May 3.

Department of Ophthalmology, Rostock University Medical Center, Rostock, Germany.

Objective: This study aims to estimate the incidence of severe binocular vision impairment and blindness (SVI/B) and to identify eye diseases and regional risk factors of persons with SVI/B at ages 50 years and older.

Methods: We designed an observational cohort study based on longitudinal, multifactorial, and administrative information of a random sample of 250,000 persons at ages 50+. All individuals were included in the process-produced health claims register of the Allgemeine Ortskrankenkasse in 2004, and were followed until 2015. Read More

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Microbiology of Acute Maxillary Sinusitis in Children.

Laryngoscope 2021 May 3. Epub 2021 May 3.

Department of Otolaryngology, Matsubara ENT Clinic, Gifu, Japan.

Objectives/hypothesis: Acute rhinosinusitis is a frequent common cold-related complication in children. Despite the need for appropriate treatment, its underlying microbiology remains unclear. This study aimed to investigate the microbiology of acute rhinosinusitis in children. Read More

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Comparing Effectiveness of Three Different Anti-VEGF Treatment Regimens for Neovascular Age-Related Macular Degeneration: Two Years' Real-World Clinical Outcomes.

Clin Ophthalmol 2021 23;15:1703-1713. Epub 2021 Apr 23.

Birmingham & Midland Eye Centre, Birmingham, UK.

Purpose: To compare and report the 2-year treatment outcomes from 3 different anti-VEGF treatment regimens in treating neovascular aged-related macular degeneration (nAMD): Ranibizumab pro re nata (Ranibizumab-PRN); Ranibizumab treat and extend (Ranibizumab-T&E); Aflibercept fixed first year dosing (7 injections) with treat and extend in subsequent year (Aflibercept-Fixed).

Methods: All treatment-naïve nAMD patients who completed 24 months of monitoring from a single treatment center were included. Patients received the initial loading dose of three injections (4-weekly interval), followed by one of the 3 treatment regimens. Read More

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J Pharmacol Exp Ther 2021 Apr 30. Epub 2021 Apr 30.

Gavin Herbert Eye Institute, Dept. of Ophthalmology, University of California, Irvine, United States

CB-5083 is an inhibitor of p97/valosin-containing protein (VCP), for which Phase I trials for cancer were terminated due to adverse effects on vision, such as photophobia and dyschromatopsia. Lower dose CB-5083 could combat inclusion body myopathy with early-onset Paget disease; and frontotemporal dementia or multisystem proteinopathy, caused by gain-of-function mutations in VCP. We hypothesized that the visual impairment in the cancer trial was due to CB-5083's inhibition of phosphodiesterase-6 (PDE6), which mediates signal transduction in photoreceptors. Read More

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The Spectrum of Maculopathy in Mitochondrial DNA A3243G Mutation: A Case Series of Six Patients.

Klin Monbl Augenheilkd 2021 Apr 30;238(4):414-417. Epub 2021 Apr 30.

Ophthalmology, Jules Gonin Eye Hospital, Lausanne, Switzerland.

Background: The mitochondrial DNA (mtDNA) A3243G point mutation encompasses a heterogenous group of disorders including mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes (MELAS), maternally inherited diabetes and deafness (MIDD), and, rarely, chronic progressive external ophthalmoplegia (CPEO). Regardless of the clinical phenotype, a specific retinopathy has been associated with the presence of this mitochondrial DNA mutation. We present six female patients exhibiting retinopathy of the A3243G point mutation at various stages. Read More

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[Nishida Extraocular Muscle Transposition Surgery for Abducens Nerve Palsy].

Klin Monbl Augenheilkd 2021 Apr 30;238(4):493-498. Epub 2021 Apr 30.

Augenklinik, Kantonsspital St. Gallen, Schweiz.

Background: Surgical treatment of abducens nerve palsy depends on the remaining function of the lateral rectus muscle. Vertical rectus transposition surgery is indicated if the attempted maximal abduction effort does not rotate the eye beyond the midline. After the first description more than 100 years ago, a variety of muscle transposition modifications have been suggested. Read More

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Clinical Classification of Acquired Concomitant Esotropia.

Klin Monbl Augenheilkd 2021 Apr 30;238(4):482-487. Epub 2021 Apr 30.

Department of Ophthalmology, University of Lausanne, Jules-Gonin Eye Hospital, Fondation Asile des aveugles, Lausanne, Switzerland.

Background: Classification and management of acquired concomitant esotropia is controversial. We sought to establish a simple clinical classification in order to determine in which cases further investigations in search of underlying pathologies are necessary.

Patients And Methods: Observational retrospective study of the files of 175 consecutive patients examined in our unit between 2009 and 2018 for acute convergent strabismus. Read More

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Visual Outcomes after Anti-VEGF Therapy for Exudative Age-Related Macular Degeneration in a Real-Life Setting.

Klin Monbl Augenheilkd 2021 Apr 30;238(4):396-402. Epub 2021 Apr 30.

Department of Ophthalmology, Cantonal Hospital St. Gallen, Switzerland.

Background: To report visual outcomes of anti-vascular endothelial growth factor (anti-VEGF) therapy for exudative age-related macular degeneration (AMD) in a real-life setting.

Patients And Methods: Retrospective case series of consecutive patients treated with either ranibizumab and/or aflibercept for monolateral or bilateral exudative AMD. A physician established the indication for treatment and administered the injections. Read More

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Swedish parents' experiences and their need for support when having a child with congenital cataract: A qualitative study.

J Pediatr Nurs 2021 Apr 27;60:109-115. Epub 2021 Apr 27.

Department of Health Sciences, Red Cross University College, Box 1059, SE 141 21 Huddinge, Sweden. Electronic address:

Purpose: To explore parents' experiences of living with a child with congenital cataract, with the intention of identifying how to improve the parental support.

Design And Method: A qualitative descriptive design using semi-structured interviews. The parents were interviewed when the children were aged 12-24 months. Read More

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Prevalence and risk factors for keratoconus in a university-based population in Turkey.

J Cataract Refract Surg 2021 Apr 5. Epub 2021 Apr 5.

Devrek State Hospital, Department of Ophthalmology, Zonguldak, Turkey Eskişehir Osmangazi University Medical School, Department of Ophthalmology, Eskişehir, Turkey.

Purpose: This study aimed to determine the prevalence of keratoconus (KC) in the students and faculty members (aged ≥18 and ≤30 years) studying/working at the Medical and Health Sciences faculties of Eskişehir Osmangazi University.

Setting: Eskişehir Osmangazi University.

Design: Prevalence study. Read More

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Knowledge and awareness of the general population and healthcare providers about retinoblastoma: it is time to know the glow.

Int J Clin Pract 2021 Apr 30:e14298. Epub 2021 Apr 30.

Department of Applied Pharmaceutical Sciences and Clinical Pharmacy, Faculty of Pharmacy, Isra University, Amman, Jordan.

Background: Retinoblastoma is the most frequent primary intraocular tumour in childhood. Early detection of retinoblastoma is the key to successful management with a higher chance of survival. This study aims to assess the knowledge of the general population and healthcare providers about retinoblastoma in term of presentation, risk factors, timing for diagnosis, and complications. Read More

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Vision loss, vision difficulty and psychological distress in South Africa: results from SANHANES-1.

BMC Psychol 2021 Apr 29;9(1):66. Epub 2021 Apr 29.

Health & Wellbeing, Human and Social Capabilities Division, Human Sciences Research Council, Cape Town, South Africa.

Background: Psychological distress in vision impairments and blindness is a complex issue and a major public health concern. Sudden adjustments in routine lifestyle and career aspirations in such persons culminate in and/or aggravate their level of stress. Yet, psychological distress in persons with visual difficulties and vision loss in South Africa is poorly understood. Read More

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Nutrition, Cognition, and Social Emotion among Preschoolers in Poor, Rural Areas of South Central China: Status and Correlates.

Nutrients 2021 Apr 16;13(4). Epub 2021 Apr 16.

International Food Policy Research Institute, 1201 Eye Street, Washington, DC 20005, USA.

Existing empirical evidence suggests that the prevalence of undernutrition in remote and poor, rural areas is still high among Chinese children. While evidence reveals that undernutrition may detrimentally affect child development, studies focusing on rural Chinese preschoolers are sparse. Using the baseline survey of a preschool's free nutritious lunch pilot program, this study examined the relationship between child undernutrition and developmental outcomes among a preschool-aged sample in poor, rural areas of China. Read More

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Preoperative Variables Associated with Surgical Outcome for the Correction of Exodeviation.

Vision (Basel) 2021 Apr 23;5(2). Epub 2021 Apr 23.

Eye Clinic, IWK Health Centre Children's Site, 5980 University Avenue, Halifax, NS B3K 6R8, Canada.

The success rate of exodeviation surgery in existing literature has been shown to be variable. This study sought to determine the success rate of surgery for exodeviation in Atlantic Canada and determine variables associated with surgical outcome. A retrospective chart review was performed, considering patients who had been assessed and surgically treated for exodeviation at the IWK Health Centre between 2011-2018. Read More

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Observations on Refractive Status and Risk Factors for Visual Impairment in Children with Disabilities.

Medicina (Kaunas) 2021 Apr 22;57(5). Epub 2021 Apr 22.

Department of Psycho-Neuroscience and Recovery, Faculty of Medicine and Pharmacy, University of Oradea, 10 December Square Street, 410028 Oradea, Romania.

Vision integrates all the senses and plays a fundamental role in the acquisition of different skills and the general development of a child. Recently, refractive errors and visual impairment have become serious health problems among children. : The aim of this study was to identify the prevalence of refractive errors and visual impairment in children with disabilities. Read More

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A Randomized Study of Nutritional Supplementation in Patients with Unilateral Wet Age-Related Macular Degeneration.

Nutrients 2021 Apr 10;13(4). Epub 2021 Apr 10.

Retinal Pathologies and New Therapies Group, Experimental Ophthalmology Laboratory, Department of Ophthalmology, Clínica Universidad de Navarra, Av. de Pío XII, 36, 31008 Pamplona, Spain.

The purpose of this study is evaluate the efficacy and safety of medicinal products containing the original Age-Related Eye Disease group (AREDS) formulation at doses approved in Europe (EU, control group; = 59) with a product that adds DHA, lutein, zeaxanthin, resveratrol and hydroxytyrosol to the formula (intervention group; = 50). This was a multicenter, randomized, observer-blinded trial conducted in patients aged 50 years or older diagnosed with unilateral exudative Age related Macular Degeneration AMD. At month 12, the intervention did not have a significant differential effect on visual acuity compared with the control group, with an estimated treatment difference in Early Treatment Diabetic Retinopathy Study (ETDRS) of -1. Read More

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