2,461 results match your criteria aged 60-70


Posttraumatic stress disorder, complex PTSD and subtypes of loneliness among older adults.

J Clin Psychol 2021 Jul 20. Epub 2021 Jul 20.

Department of Psychology, Maynooth University, Kildare, Ireland.

Objectives: Research examining the relationship between loneliness and Complex Posttraumatic Stress Disorder (CPTSD) is scarce, particularly among older adults. CPTSD includes the core symptoms of PTSD along with additional symptoms reflecting "disturbances in self-organisation" (DSO). This study examined the cross-sectional relationships between loneliness (emotional and social loneliness) and CPTSD symptoms (i. Read More

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Economic and health impacts of introducing Helicobacter pylori eradication strategy into national gastric cancer policy in Japan: A cost-effectiveness analysis.

Helicobacter 2021 Jul 18:e12837. Epub 2021 Jul 18.

Advanced Research Promotion Center, Health Sciences University of Hokkaido, Ishikari gun, Japan.

Background: Helicobacter pylori (H. pylori) eradication reduces gastric cancer risk. Since 2013, a population-wide H. Read More

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Differential gene expression in liver of colored broiler chicken divergently selected for residual feed intake.

Trop Anim Health Prod 2021 Jul 16;53(3):403. Epub 2021 Jul 16.

College of Veterinary Science, GADVASU, Rampura Phul, Bathinda, Punjab, India.

Feed constitutes about 60-70% of the total cost of poultry production. So maximizing the feed efficiency will reduce production cost. The rapid growth in the juvenile period is essential to achieve higher body weight. Read More

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Individual Postprandial Glycemic Responses to Diet in n-of-1 Trials: Westlake N-of-1 Trials for Macronutrient Intake (WE-MACNUTR).

J Nutr 2021 Jul 13. Epub 2021 Jul 13.

Key Laboratory of Growth Regulation and Translational Research of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, China.

Background: The role of different types and quantities of macronutrients on human health has been controversial, and the individual response to dietary macronutrient intake needs more investigation.

Objectives: We aimed to use an 'n-of-1' study design to investigate the individual variability in postprandial glycemic response when eating diets with different macronutrient distributions among apparently healthy adults.

Methods: Thirty apparently healthy young Chinese adults (women, 68%) aged between 22 and 34 y, with BMI between 17. Read More

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Patients with Coronary Artery Disease Have Lower Levels of Antibody to Heat-Stressed Fibroblast Derived Proteins, versus Normal Subjects.

Cardiovasc Ther 2021 17;2021:5577218. Epub 2021 Jun 17.

Cellular and Molecular Biology Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.

Cellular stress response plays an important role in the pathophysiology of coronary artery disease (CAD). Inhibition of cellular stress may provide a novel clinical approach regarding the diagnosis and treatment of CAD. Fibroblasts constitute 60-70% of cardiac cells and have a crucial role in cardiovascular function. Read More

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Loneliness and health expectancy among older adults: A longitudinal population-based study.

J Am Geriatr Soc 2021 Jul 7. Epub 2021 Jul 7.

Centre for Ageing Research and Education (CARE), Duke-NUS Medical School, Singapore, Singapore.

Background: The population health impact of loneliness remains unknown. We quantified the impact of loneliness on total life expectancy (TLE) and health expectancy (the duration of remaining life lived in different health states) among older adults, aged ≥60 years.

Design: Multistate life table analysis of a nationally representative longitudinal survey. Read More

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Dietary Sodium Nitrate Activates Antioxidant and Mitochondrial Dynamics Genes after Moderate Intensity Acute Exercise in Metabolic Syndrome Patients.

J Clin Med 2021 Jun 14;10(12). Epub 2021 Jun 14.

Research Group on Community Nutrition and Oxidative Stress, Health Research Institute of the Balearic Islands (IdISBa), 07120 Palma, Spain.

Exercise can induce a pro-inflammatory response in aged subjects with metabolic disorders and nitrate supplementation has shown anti-inflammatory effects. We evaluated the influence of dietary nitrate on the response of the antioxidant and mitochondrial dynamics genes to acute exercise in peripheral blood mononuclear cells (PBMCs), as well as the antioxidant and the inflammatory response of PBMCs against immune stimulation. Metabolic syndrome patients participated in a crossover study in which they consumed a beverage containing 16 mM sodium nitrate or a placebo with the same composition without nitrate before performing a submaximal test at 60%-70% of their maximal heart rate for 30 min. Read More

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Optimizing Spatial Allocation of COVID-19 Vaccine by Agent-Based Spatiotemporal Simulations.

Geohealth 2021 Jun 1;5(6):e2021GH000427. Epub 2021 Jun 1.

School of Geography and Planning Sun Yat-sen University Guangzhou China.

Optimizing allocation of vaccine, a highly scarce resource, is an urgent and critical issue during fighting against on-going COVID-19 epidemic. Prior studies suggested that vaccine should be prioritized by age and risk groups, but few of them have considered the spatial prioritization strategy. This study aims to examine the spatial heterogeneity of COVID-19 transmission in the city naturally, and optimize vaccine distribution strategies considering spatial prioritization. Read More

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Polycythemia vera as a rare cause of hypertension in a young man.

BMJ Case Rep 2021 Jun 23;14(6). Epub 2021 Jun 23.

Department of Faculty Therapy #2, I M Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.

Polycythemia vera (PV) is an orphan haematological disease and one of the most common myeloproliferative diseases, with the incidence rate of about 0.4-2.8 cases per 100 000 population per year. Read More

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Growth differentiation factor 15 associations with clinical features of chronic heart failure with midrange ejection fraction and preserved ejection fraction depending on the history of myocardial infarction.

Kardiologiia 2021 May 31;61(5):59-64. Epub 2021 May 31.

Research Institute for Cardiology, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk, Russia.

Aim    To analyze associations between levels of the inflammatory marker, growth differentiation factor 15 (GDF-15), and echocardiographic indexes in CHF patients with mid-range and preserved left ventricular ejection fraction (LV EF) depending on the history of myocardial infarction (MI).Material and methods    This study included 34 CHF patients with preserved and mid-range LV EF after MI (group 1, n=19) and without a history of MI (group 2, n=15). Serum concentration of GDF-15 was measured with enzyme immunoassay (BioVendor, Czech Republic). Read More

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Quality of Movement Is Associated With Cognitive Function in Physically Inactive Older Women.

J Aging Phys Act 2021 Jun 9:1-6. Epub 2021 Jun 9.

The relationship between the quality of movement, considering different global and universal basic patterns of movement and cognition domains in older adults remain unclear. The current study explored this association in physically inactive older women. In total, 187 participants, aged 60-70 years (mean = 64. Read More

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Analysis of the epidemiological and clinical characteristics of 65 patients with scrub typhus on the east coast of China.

Ann Palliat Med 2021 May;10(5):5694-5705

Department of Emergency Medicine, Affiliated Hospital of Nantong University, Nantong, China.

Background: The present study set out to investigate the epidemiological and clinical characteristics of 65 patients with tsutsugamushi disease.

Methods: The clinical data of 65 patients with tsutsugamushi disease, who were admitted to the Affiliated Hospital of Nantong University were retrospectively analyzed. The clinical symptoms, laboratory examination results, clinical treatment plans, treatments, and outcomes of the patients were analyzed. Read More

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Subjective expectations concerning life expectancy and age-related health burden

Orv Hetil 2021 06 6;162(23):911-923. Epub 2021 Jun 6.

1 Óbudai Egyetem, Egyetemi Kutatási és Innovációs Központ, Egészségügyi Közgazdaságtan Kutatóközpont, Budapest, Bécsi út 96/b, 1034.

Összefoglaló. Bevezetés: A lakosság idősödésével növekvő betegségteher egyéni és társadalmi szinten is fokozódó nyomást jelent. Célkitűzés: Felmérni a hazai általános felnőtt lakosságnak a korlátozottsággal, a gondozási igényekkel és a munkavégzéssel kapcsolatos időskori szubjektív várakozásait. Read More

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Prediction of One Repetition Maximum Using Reference Minimum Velocity Threshold Values in Young and Middle-Aged Resistance-Trained Males.

Behav Sci (Basel) 2021 May 7;11(5). Epub 2021 May 7.

Department of Sport and Exercise Sciences, University of Chester, Chester CH1 4BJ, UK.

Background: This study determined the accuracy of different velocity-based methods when predicting one-repetition maximum (1RM) in young and middle-aged resistance-trained males.

Methods: Two days after maximal strength testing, 20 young (age 21.0 ± 1. Read More

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The differential demographic pattern of coronavirus disease 2019 fatality outside Hubei and from six hospitals in Hubei, China: a descriptive analysis.

BMC Infect Dis 2021 May 26;21(1):481. Epub 2021 May 26.

State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071, P. R. China.

Background: The coronavirus disease 2019 (COVID-19) epidemic has been largely controlled in China, to the point where case fatality rate (CFR) data can be comprehensively evaluated.

Methods: Data on confirmed patients, with a final outcome reported as of 29 March 2020, were obtained from official websites and other internet sources. The hospitalized CFR (HCFR) was estimated, epidemiological features described, and risk factors for a fatal outcome identified. Read More

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[THE NEED FOR REDUCING DISPARITIES IN SARS-COV-2 IMMUNIZATION: THE ULTRAORTHODOX AND ARAB POPULATIONS IN ISRAEL].

Harefuah 2021 May;160(5):285-290

School of Public Health, Sackler Faculty of Medicine, Tel Aviv University.

Introduction: Immunization against coronavirus disease 2019 (COVID-19) in Israel began on December 2020, using the BNT162b2 mRNA vaccine. Individuals aged 60 years or older and medical staff were prioritized in COVID-19 immunization, and currently individuals aged 16 years or older are eligible to receive the vaccine. To achieve levels of community immunity (herd immunity) immunization of 60-70% of the population is required. Read More

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Public health impact of delaying second dose of BNT162b2 or mRNA-1273 covid-19 vaccine: simulation agent based modeling study.

BMJ 2021 05 12;373:n1087. Epub 2021 May 12.

Department of Medicine, Mayo Clinic, Rochester, MN, USA

Objective: To estimate population health outcomes with delayed second dose versus standard schedule of SARS-CoV-2 mRNA vaccination.

Design: Simulation agent based modeling study.

Setting: Simulated population based on real world US county. Read More

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The cancer patient's perspective of COVID-19-induced distress-A cross-sectional study and a longitudinal comparison of HRQOL assessed before and during the pandemic.

Cancer Med 2021 06 10;10(12):3928-3937. Epub 2021 May 10.

Department of Internal Medicine V, Hematology and Oncology, Comprehensive Cancer Center Innsbruck (CCCI), Medical University of Innsbruck, Innsbruck, Austria.

Background: To permit timely mitigation of adverse effects on overall clinical outcome, it is essential to understand how the pandemic influences distress and health-related quality of life (HRQOL) in cancer patients during the coronavirus disease 2019 (COVID-19) pandemic.

Methods: In this cross-sectional study, adult cancer patients, without COVID-19 symptoms, completed a 13-item questionnaire about the pandemic's impacts on distress and everyday-life; associations with age, sex, or impaired HRQOL were then assessed by binary logistic regressions. In a subsample of patients with HRQOL assessment available from both before and during the pandemic, we evaluated the pandemic's impact on longitudinal changes in HRQOL reported within 6 months before versus during the COVID-19 lockdown using McNemar's test, and thresholds for clinical importance. Read More

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Evaluation of occlusal status of Japanese adults based on functional tooth units.

Int Dent J 2021 May 5. Epub 2021 May 5.

Department of Oral Health Promotion, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.

Objectives: Although extensive national oral health data on dental caries and periodontal diseases in Japan are available, few studies have assessed the occlusal status of the Japanese population, and none are based on national survey data. The presence and prosthodontic conditions of the molar region are important for masticatory function, and the functional tooth unit (FTU) approach can be used to evaluate the occlusal status. Thus, using the national oral health survey data, this study investigated the occlusal status of the Japanese population using FTU. Read More

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Relationship between plasma asymmetric dimethylarginine and nitric oxide levels affects aerobic exercise training-induced reduction of arterial stiffness in middle-aged and older adults.

Phys Act Nutr 2021 Mar 31;25(1):16-22. Epub 2021 Mar 31.

Faculty of Sport and Health Science, Ritsumeikan University, Shiga, Japan.

Purpose: Aerobic exercise training (AT) reverses aging-induced deterioration of arterial stiffness via increased arterial nitric oxide (NO) production. Asymmetric dimethylarginine (ADMA), an endogenous inhibitor of NO synthase, was decreased by AT. However, whether AT-induced changes in ADMA levels are related to changes in nitrite/nitrate (NOx) levels remains unclear. Read More

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The relationships between the topological properties of the whole-brain white matter network and the severity of autism spectrum disorder: A study from monozygotic twins.

Neuroscience 2021 06 20;465:60-70. Epub 2021 Apr 20.

Children's Mental Health Research Center, the Affiliated Brain Hospital of Nanjing Medical University, Nanjing GuangZhou Road 264, Nanjing 210029, China. Electronic address:

Twins provide a valuable perspective for exploring the pathological mechanism of autism spectrum disorder (ASD). We aim to analyze differences in the topological properties of the white matter (WM) network between monozygotic twins with ASD (MZCo-ASD) and children with typical development (TD). We enrolled 67 subjects aged 2-9 years. Read More

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Natural history of lung function over one year in patients with Parkinson's disease.

Respir Med 2021 Jun 16;182:106396. Epub 2021 Apr 16.

Acorda Therapeutics, Inc., Ardsley, NY, USA.

Background: Little is known about decline in lung function in Parkinson's disease (PD). To assess these changes, we assessed the changes in lung function that occurred over 12 months in patients on standard PD therapy as part of the observational cohort of an open-label study of inhaled levodopa (CVT-301) in PD.

Methods: PD patients on stable oral PD therapy and no chronic respiratory disease had spirometry and diffusing capacity of the lungs for carbon monoxide (DL) measured at 3, 6, 9, and 12 months. Read More

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History of healthcare use and disease burden in older adults with different levels of alcohol use. A register-based cohort study.

Alcohol Clin Exp Res 2021 06 6;45(6):1237-1248. Epub 2021 May 6.

Unit of Clinical Alcohol Research, Institute of Clinical Research, University of Southern Denmark, Odense C, Denmark.

Background: Only a minority of individuals with problematic alcohol use ever seek alcohol treatment. Knowledge of general help-seeking behavior in the healthcare system can identify possibilities for prevention and intervention.

Method: The current study describes healthcare use, burden of disease, and prior morbidities over a 15-year period by current alcohol use behavior among Danish adults aged 60-70. Read More

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The effect of gotu kola (Centella asiatica L.) tea on blood pressure of hypertension.

Enferm Clin 2021 04;31 Suppl 2:S195-S198

Public Health Department, Insan Unggul School of Health, Surabaya, East Java, Indonesia.

Hypertension is an increase in systolic or diastolic blood pressure that exceeds the threshold. In this research used gotu kola (Centella asiatica L.), which is contains several compounds that can act as anti-hypertension. Read More

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Prevalence of Face Mask Wearing in Northern Vermont in Response to the COVID-19 Pandemic.

Public Health Rep 2021 Jul-Aug;136(4):451-456. Epub 2021 Apr 13.

238330 Essex High School, Essex Junction, VT, USA.

Objectives: Information on the prevalence of face mask use to reduce the spread of SARS-CoV-2 is needed to model disease spread and to assess the effectiveness of policies that encourage face mask use. We sought to (1) estimate the prevalence of face mask use in northern Vermont and (2) assess the effect of age and sex on the likelihood of face mask use.

Methods: We monitored the entrances to public businesses and visually assessed age, sex, and face mask use. Read More

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Effect of Yogasana Intervention on Standing Balance Performance among People with Diabetic Peripheral Neuropathy: A Pilot Study.

Int J Yoga 2021 Jan-Apr;14(1):60-70. Epub 2021 Feb 5.

Medical Director, Vivekanada Yoga Anusandhana Samasthana, Bengaluru, Karnataka, India.

Background: Diabetic peripheral neuropathy (DPN) is known to cause impaired balance and eventually increased risk of fall. Yogasanas characterized by slow, gentle transitions into postures with a varying base of support and focus on body awareness during movement hold potential for training balance control. Therefore, the current study aimed to evaluate effect of structured Yogasana intervention compared to conventional balance exercise on static and dynamic balance performance among people with diabetic neuropathy. Read More

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February 2021

A Low-Fat Diet Combined with Moderate-Intensity Aerobic Exercise is More Effective than a Low-Fat Diet or Aerobic Exercise Alone on Dyslipidemia and Depression Status in Obese Patients: A Randomized Controlled Trial.

Endocr Metab Immune Disord Drug Targets 2021 Apr 6. Epub 2021 Apr 6.

Department of Basic Medical Sciences, Collage of Medicine, Prince Sattam bin Abdulaziz University, Al-Kharj. Saudi Arabia.

Background: It was defined that exercise and dietary interventions are used to control dyslipidemia and depression in obese individuals, whilst rare investigations have examined the concurrent effects of a low-fat diet and moderate-intensity aerobic exercise training (MIAET) on dyslipidemia and depression in obese patients. Hence, we assessed the potential influences of a low-fat diet combined with MIAET on blood lipids and depression in those individuals.

Methods: Forty-two obese patients aged 30-50 years have been enrolled in this randomized controlled trial. Read More

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First Report of Fruit Canker Caused by Nothophoma quercina on Chinese quince in South Korea.

Plant Dis 2021 Apr 6. Epub 2021 Apr 6.

Kyungpook National University, 34986, School of Applied Biosciences, Daegu, Daegu, Korea (the Republic of);

The Chinese quince ( (Thouin) CK Schneid.) is a tree that is commonly distributed in all regions of South Korea and other Asian countries. The ripened yellow fruit contains medically active compounds (Hamauzu et al. Read More

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Hemoglobin A1c Levels Associated with Age and Gender in Taiwanese Adults without Prior Diagnosis with Diabetes.

Int J Environ Res Public Health 2021 03 25;18(7). Epub 2021 Mar 25.

Department of Orthopedics, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 807, Taiwan.

Several studies have reported that Hemoglobin A1c (HbA1c) levels increase with age for people without diabetes. However, HbA1c levels associated with age and gender have not been well investigated for Taiwanese adults. The objective of this study was to investigate the sex-specific association between HbA1c levels and age for Taiwanese adults without diabetes. Read More

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Characteristics of Physical Exercise Programs for Older Adults in Latin America: A Systematic Review of Randomized Controlled Trials.

Int J Environ Res Public Health 2021 03 10;18(6). Epub 2021 Mar 10.

Escuela de Kinesiología, Facultad de Salud, Universidad Santo Tomás, Los Ángeles 4440000, Chile.

Aim: To characterize physical exercise programs for older adults in Latin America.

Methods: This review was conducted in accordance with the PRISMA statement. A search for randomized controlled trials (RCTs) published between the years 2015 and 2020 was performed in the Scopus, MedLine and SciELO databases. Read More

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