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Association between nonpharmacological strategies and delirium in intensive care unit.

Nurs Crit Care 2022 Jan 20. Epub 2022 Jan 20.

Escola Paulista de Enfermagem, Universidade Federal de São Paulo, São Paulo, Brazil.

Background: Several nonpharmacological strategies for the prevention and treatment of delirium have been increasingly used because the aetiology of delirium is multifactorial.

Aims: To verify the association between nonpharmacological strategies (presence of companion, mobilization, absence of physical restraint and natural light) and the occurrence of delirium, and to identify risk factors for delirium in intensive care unit (ICU) patients.

Study Design: The study was conducted in a Brazilian medical and surgical ICU. Read More

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January 2022

Trends in the amyloidosis mortality rate in Japan: A nationwide observational study from 1998 to 2019.

Geriatr Gerontol Int 2022 Jan 20. Epub 2022 Jan 20.

Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.

Aim: Despite the increasing attention that has been paid to amyloidosis in recent years, there have been few reports on amyloidosis mortality and its trends worldwide. This study aimed to evaluate the trends in crude and age-adjusted amyloidosis-associated mortality rates in Japan from 1998 to 2019.

Methods: We used national Vital Statistics data among older adults aged over 50 years. Read More

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January 2022

Effect of Varying Repositioning Frequency on Pressure Injury Prevention in Nursing Home Residents: The TEAM-UP Randomized Clinical Trial Results.

Adv Skin Wound Care 2022 Jan 19. Epub 2022 Jan 19.

Tracey L. Yap, PhD, RN, CNE, WCC, FGSA, FAAN, Duke University School of Nursing, Durham, North Carolina, United States. Susan D. Horn, PhD, University of Utah School of Medicine, Salt Lake City, Utah. Phoebe D. Sharkey, PhD, Loyola University Maryland, Baltimore. Tianyu Zheng, MS, University of Utah Department of Population Health Sciences, Salt Lake City. Nancy Bergstrom, PhD, RN, FAAN, University of Texas Health Science Center at Houston School of Nursing. Cathleen Colon-Emeric, MD, Duke University School of Medicine. Valerie K. Sabol, PhD, MBA, ACNP, GNP, FAANP, FAAN, Duke University School of Nursing. Jenny Alderden, PhD, APRN, University of Utah College of Nursing. Winston Yap, MD, Carroll County Memorial Hospital, Carrollton, Kentucky. Susan M. Kennerly, PhD, RN, CNE, WCC, FAAN, East Carolina University College of Nursing, Greenville, North Carolina. Acknowledgments: The authors thank Judith Hayes, PhD, RN, and Elizabeth Flint, PhD, for editorial assistance. This project was funded by the National Institutes of Health, National Institute of Nursing Research (R01NR016001) Yap, PI. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. The authors have disclosed no other financial relationships related to this article. Submitted December 5, 2021; accepted December 23, 2021.

Objective: To investigate the clinical effectiveness of three repositioning intervals (2-, 3-, or 4-hour intervals) without compromising pressure injury (PI) incidence.

Methods: An embedded pragmatic cluster randomized controlled trial was conducted in nine nursing homes (NH) that were randomly assigned to one of three repositioning intervals. Baseline and 4-week intervention data were provided. Read More

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January 2022

The Relation of End-tidal CO2 Values With Infarct Volume and Early Prognosis in Patients With Acute Ischemic Stroke.

Neurologist 2022 Jan 20. Epub 2022 Jan 20.

Departments of Emergency Neurology Radiology, Tepecik Training and Research Hospital, University of Health Sciences Department of Neurology, Izmir Medicana International Hospital Department of Biostatistics and Medical Informatics, Faculty of Medicine, Ege University, Izmir, Turkey.

Background: The aim of this study is to reveal the relationship between end-tidal CO2 (EtCO2) values with infarct volume and early prognosis in patients diagnosed with acute ischemic stroke in the emergency department.

Materials And Methods: This prospective cross-sectional study was conducted in a tertiary hospital. The demographics, characteristics, EtCO2, volume of the stroke area on diffusion-weighted magnetic resonance imaging and the modified Rankin Scale (mRS) of the patients were recorded. Read More

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January 2022

Predictors of Advance Care Planning Engagement Among Muslim Americans.

J Hosp Palliat Nurs 2022 Jan 19. Epub 2022 Jan 19.

Ghaith A. Bani Melhem, PhD, MSN, RN, is assistant professor, Royal Medical Services College for Allied Health Professions, Al-Balqa Applied University, Amman, Jordan. Debra C. Wallace, PhD, RN, FAAN, is professor, Department of Family and Community Nursing, University of North Carolina at Greensboro. Judith A. Adams, PhD, MSN, RN, FNP-BC, is assistant professor, School of Nursing, University of North Carolina at Greensboro. Ratchneewan Ross, PhD, RN, FAAN, is professor, School of Nursing, University of North Carolina Greensboro. S. Sudha, PhD, is associate professor, Department of Human Development and Family Studies, University of North Carolina Greensboro.

Advance care planning (ACP) enables people to discuss their physical, psychological, social, and spiritual needs before nearing death. Most literature examining the determinants of ACP engagement is limited and does not include minority faith communities in the United States, including Muslim communities. The purpose of this cross-sectional correlational study was to examine ACP engagement determinants among Muslims in the United States. Read More

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January 2022

Risk Factors for Rebound After Correction of Genu Valgum in Skeletal Dysplasia Patients Treated by Tension Band Plates.

J Pediatr Orthop 2022 Jan 20. Epub 2022 Jan 20.

Department of Orthopaedics, Nemours Childrens Hospital, Delaware, Wilmington, DE.

Background: Growth modulation using tension band plates (TBPs) is increasingly important for lower limb deformity correction in patients with skeletal dysplasia (SKD). Development of rebound deformity is a concern after TBP removal. Data regarding this complication are rare; therefore, we evaluated the prevalence and risk factors for rebound deformity in children with SKD undergoing correction of genu valgum using TBP. Read More

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January 2022

Epidural Analgesia Versus Lumbar Plexus Blockade After Hip Reconstruction Surgery in Children With Cerebral Palsy and Intrathecal Baclofen Pumps: A Comparison of Safety and Efficacy.

J Pediatr Orthop 2022 Jan 20. Epub 2022 Jan 20.

Departments of Orthopaedic Surgery Anesthesiology, Critical Care, and Pain Medicine Neurosurgery, Boston Children's Hospital, Boston, MA.

Background: Epidural analgesia is commonly used for pain control after reconstructive hip surgery, but its use is controversial in the presence of an intrathecal baclofen pump (ITB). The purpose of this retrospective study was to investigate the rate of serious anesthetic and postoperative complications as well as the efficacy of epidural analgesia compared with lumbar plexus blocks (LPBs) for pain management after neuromuscular hip reconstruction in children with cerebral palsy (CP) and ITB.

Methods: Pediatric patients with CP and ITB undergoing hip reconstructive surgery from 2010 to 2019 were retrospectively identified. Read More

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January 2022

Female Reproductive Ageing and Chromosomal Abnormalities in a Large Series of Women Undergoing IVF.

Cytogenet Genome Res 2022 Jan 20:1-5. Epub 2022 Jan 20.

Genesis Genoma Lab, Genetic Diagnosis, Clinical Genetics & Research, Athens, Greece.

Chromosomal abnormalities are often detected in women with reproductive problems. This study aimed to investigate the presence and type of chromosomal aberrations in peripheral blood of women undergoing in vitro fertilization (IVF) and their possible association with advanced maternal age (AMA). A total of 1,837 women undergoing IVF between 2016 and 2019 were enrolled in the study. Read More

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January 2022

Seasonal variation and risk of febrile seizures; a Danish nationwide cohort study.

Neuroepidemiology 2022 Jan 20. Epub 2022 Jan 20.

Introduction Onset of febrile seizures varies with calendar season. However, it has not previously been assessed, how season of birth interacts with age and peak risk of febrile seizures, and whether season of birth correlates with the cumulative risk of febrile seizures at 5 years of age (i.e. Read More

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January 2022

Retacrit®, Biosimilar of Epoetin alfa, in Chemotherapy-Induced Anemia in Routine Practice: Impact of Iron Supplementation.

Oncology 2022 Jan 20. Epub 2022 Jan 20.

Introduction: To evaluate in real-life conditions the effectiveness and safety of a biosimilar of epoetin alpha (Retacrit®) in chemotherapy-induced anemia and the impact of iron supplementation.

Methods: This was a longitudinal, observational, prospective study of 12-16 weeks conducted in 195 French centers. The primary endpoint was the achievement of target Hb (with an increase of Hb 1 g/dL) or an increase of Hb 2 g/dL, in the absence of transfusion in the previous 3 weeks. Read More

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January 2022

Long-Term Outcomes and Prognostic Factors of Patients with Metastatic Solid Tumors Admitted to the Intensive Care Unit.

Oncology 2022 Jan 20:1-9. Epub 2022 Jan 20.

Department of Medical Oncology, Centre Oscar Lambret, Lille, France.

Introduction: Admission of metastatic cancer patients to the intensive care unit (ICU) poses medical and ethical challenges in the absence of reliable prognostic tools to guide decision-making.

Material And Methods: We retrospectively analyzed the medical charts of 129 consecutive patients with metastatic solid tumors admitted to the ICU between January and September 2014 and identified prognostic factors (PFs) using Cox models.

Results: The mean patient age at ICU admission was 58. Read More

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January 2022

Leisure-Time and Transport-Related Physical Activity and the Risk of Mortality: The CRONICAS Cohort Study.

J Phys Act Health 2022 Jan 20:1-7. Epub 2022 Jan 20.

Background: The long-term health association of the leisure-time and transport-related physical activity domains of the International Physical Activity Questionnaire have not been established in Latin American settings. The authors aimed to quantify the 7-year all-cause mortality risk associated with levels of leisure-time and transport-related physical activity.

Methods: Ongoing prospective cohort study conducted in 4 sites in Peru. Read More

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January 2022

The influence of peripheral emotions on inhibitory control among children.

Acta Psychol (Amst) 2022 Jan 17;223:103507. Epub 2022 Jan 17.

Multilingualism Research Team, Institute for Research and Development (IFE), University College of Teacher Education, Tyrol, Austria; Diversity and Inclusion Research Group University of Potsdam, Germany. Electronic address:

In this study, we investigated the cognitive-emotional interplay by measuring the effects of executive competition (Pessoa, 2013), i.e., how inhibitory control is influenced when emotional information is encountered. Read More

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January 2022

Taking the strain: An examination of upper back musculoskeletal tissue sensitivity in relation to upper back pain and breast size. A cross-sectional study.

Clin Biomech (Bristol, Avon) 2022 Jan 6;92:105571. Epub 2022 Jan 6.

School of Physiotherapy and Exercise Science, Curtin University, Western Australia, Australia. Electronic address:

Background: The physiological basis for upper back pain experienced by women with large breasts is unclear but could relate to sensitivity of musculoskeletal tissues strained from the postural adaptations to large breasts. The aim of this cross-sectional study was to examine if upper back pain and breast size were associated with greater localised sensitivity of upper back musculoskeletal tissues.

Methods: 119 healthy postmenopausal women (mean age 61 years) had their upper back pain (numerical rating scale), breast size (breast size score), and upper back tissue sensitivity (pressure pain thresholds (digital algometry, kPa)) assessed. Read More

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January 2022

JAK2 allele burden is correlated with a risk of venous but not arterial thrombosis.

Thromb Res 2022 Jan 14;211:1-5. Epub 2022 Jan 14.

Department of Vascular Medicine, CHU Amiens-Picardie, France; EA7516 CHIMERE, Université Jules Vernes Picardie, Amiens, France.

Background: Thrombosis is the main complication in myeloproliferative neoplasms (MPN). A JAK2V617F mutation has been shown to be a risk factor for thrombosis. The implication of other risk factors alongside a mutation allele burden needs to be clarified (Trifa et al. Read More

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January 2022

Two-year anatomical and functional outcomes of laparoscopic sacrocolpopexy using light-weight Y shaped mesh for post hysterectomy vaginal prolapse.

Eur J Obstet Gynecol Reprod Biol 2022 Jan 10;270:139-143. Epub 2022 Jan 10.

Yarmouk University, Faculty of Medicine Irbid, Jordan.

Objective: The aim of this study is to evaluate the efficacy, safety, anatomical and functional outcomes of patients undergoing laparoscopic sacrocolpopexy (LSC) using light-weight Y mesh for post hysterectomy vaginal prolapse.

Study Design: A retrospective observational study of women who underwent LSC for post hysterectomy vaginal vault prolapse between January 2010 and January 2019. Y shaped mesh was used for the LSC after dissection of the rectum and the bladder. Read More

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January 2022

Geographical variations in the association between bullying victimization and sleep loss among adolescents: a population-based study of 91 countries.

Sleep Med 2021 Dec 31;90:1-8. Epub 2021 Dec 31.

Institute for Social Science Research, The University of Queensland, Indooroopilly, Queensland 4068, Australia; The Australian Research Council Centre of Excellence for Children and Families over the Life Course (The Life Course Centre), The University of Queensland, Indooroopilly, Queensland 4068, Australia.

Objective: To examine geographical variations in the association between bullying victimization and sleep loss over worry among adolescents.

Methods: We used data from the Global School-based Student Health Survey conducted between 2003 and 2017 in 91 countries across the globe. Sleep loss was categorised as: none/minimum (reported never or rarely sleep loss), moderate (reported sometimes), and severe (reported most of the time or always). Read More

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December 2021

A video-based discussion of movement disorders in paediatric anti NMDAR encephalitis: A case series from Eastern India.

Eur J Paediatr Neurol 2022 Jan 13;37:40-45. Epub 2022 Jan 13.

Department of Neurology, Bangur Institute of Neurology, IPGMER SSKM Hospital, Kolkata, West Bengal, India. Electronic address:

Purpose: The spectrum of movement disorders associated with anti N-Methyl-d-Aspartate-Receptor (NMDAR) encephalitis is myriad, particularly in children, possibilities of which were investigated from two tertiary care centres.

Methods: A retrospective study was conducted in two tertiary referral centres in Eastern India, analysing data of 8 paediatric patients diagnosed as anti NMDAR encephalitis, presenting with one or more movement disorders (MDs).

Results: All the patients were of Bengali ethnicity with a median age of 9 years (3-16 years) and with female predilection (62. Read More

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January 2022

The characteristics of patients receiving psychotropic pro re nata medication at discharge for the treatment of schizophrenia and major depressive disorder: A nationwide survey from the EGUIDE project.

Asian J Psychiatr 2022 Jan 13;69:103007. Epub 2022 Jan 13.

Department of NeuroPsychiatry, Tokyo Metropolitan Tama Medical Center, 2-8-29 Musashidai, Fuchu, Tokyo 183-8524, Japan.

Background: Although several guidelines indicate that daily pharmacotherapy is an important part of the treatment of schizophrenia and major depressive disorder, there are few reports regarding pro re nata (PRN) prescriptions. The purpose of this study is to clarify the characteristics of patients receiving psychotropic PRN prescription for the treatment of schizophrenia and major depressive disorder.

Method: We used data from 'the effectiveness of guideline for dissemination and education in psychiatric treatment' (EGUIDE) project to evaluate the presence or absence of psychotropic PRN prescription at the time of discharge, the age and sex of patients receiving PRN prescription for each diagnosis, and the association between PRN prescription and regular daily psychotropics. Read More

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January 2022

Tailoring maintenance chemotherapy upon response to induction chemotherapy as compared with pemetrexed continuation maintenance in advanced non-squamous NSCLC patients: Results of the IFCT-GFPC-1101 multicenter randomized phase III trial.

Lung Cancer 2021 Nov 30;164:84-90. Epub 2021 Nov 30.

Cancer Research Centre Léon-Bérard, Lyon, France.

Background: Benefit from maintenance in advanced non-squamous non-small cell lung cancer (NS-NSCLC) might favor switch maintenance after disease stabilization (SD) and continuation after objective response (OR). This trial assessed a maintenance strategy conditioned by response to cisplatin-gemcitabine (CG) with G continuation for patients with OR or switch to pemetrexed (P) for patients with SD as compared with a control arm based on the Paramount regimen.

Methods: Eligibility criteria: age 18-70 years, ECOG PS 0-1, untreated stage IV NS-NSCLC without EGFR or ALK alteration, ineligibility to bevacizumab. Read More

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November 2021

Validation of a predictive model for identifying an increased risk for recurrence in adolescents and young adults with a first provoked thromboembolism.

Blood Cells Mol Dis 2022 Jan 14;94:102651. Epub 2022 Jan 14.

Institute of Clinical Chemistry, Univ. Hospital Kiel & Lübeck, Germany. Electronic address:

Background: To develop and validate a predictive model to determinate patients at increased risk to suffer from recurrence following a first provoked deep vein thrombosis (VTE).

Methods: Predictive variables, i.e. Read More

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January 2022

Elderly versus nonelderly patients with invasive fungal infections: species distribution and antifungal resistance, SENTRY antifungal surveillance program 2017-2019.

Diagn Microbiol Infect Dis 2021 Dec 24;102(4):115627. Epub 2021 Dec 24.

JMI Laboratories, North Liberty, IA. Electronic address:

We utilized the SENTRY surveillance database from 2017 through 2019 to address pathogen frequency and antifungal resistance among 4,497 clinical isolates of fungi from patients who were either ≥ 65 years (2,170 isolates) or between 18 and 64 years of age (2,327 isolates). The younger population was more frequently infected with non-Candida yeasts and non-Aspergillus moulds. Candida glabrata was more common in the older age group (P value = 0. Read More

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December 2021

Association between asthma control trajectories in preschoolers and long-term asthma control.

J Allergy Clin Immunol Pract 2022 Jan 17. Epub 2022 Jan 17.

Research Centre, Centre Hospitalier Universitaire Sainte-Justine, Montreal, Québec, CA; Department of Pediatrics, University of Montreal, Montreal, Québec, CA; Department of Social and Preventive Medicine, Montreal, Québec, CA.

Background: The potential influence of asthma control in early life on long-term outcomes in childhood remains largely unknown.

Objective: To examine whether asthma control trajectories in the 2 years post-diagnosis in preschoolers are associated with long-term unsatisfactory asthma control.

Methods: We conducted a multicenter population-based retrospective cohort study, including 4 Canadian provincial birth cohorts derived from administrative databases. Read More

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January 2022

Posterior hinge fixation for the treatment of unstable traumatic sacroiliac joint injuries.

Orthop Traumatol Surg Res 2022 Jan 17:103203. Epub 2022 Jan 17.

CHU de Rouen, Institut Régional du Rachis, Service de chirurgie orthopédique et traumatologique, 1, rue de Germont, 76 000 Rouen, France.

Introduction: Posterior hinge fixation (PHF) is a sacroiliac joint fixation method indicated for the surgical treatment of unstable pelvic ring fractures (Tile C).

Hypothesis: PHF yields good functional outcomes based on the Majeed score at more than 1 year of follow-up.

Methods: A single-center, retrospective study of patients who had a Tile C pelvic ring fracture, who were operated by PHF and who were evaluated at a minimum follow-up of 1 year. Read More

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January 2022

Prevalence of fatty liver disease after liver transplantation and risk factors for recipients and donors.

Ann Hepatol 2022 Jan 17:100670. Epub 2022 Jan 17.

Institute of Gastroenterology, Department of Internal Medicine, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo 162-8666, Japan.

Introduction And Objectives: Fatty liver disease (FLD) may develop in liver transplant recipients. We investigated the recipient and donor risk factors for FLD development after liver transplantation (LT).

Methods: A total of 108 liver transplant recipients (54 men [50. Read More

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January 2022

Auditory hindsight bias in school-age children.

J Exp Child Psychol 2022 Jan 17;217:105346. Epub 2022 Jan 17.

Department of Psychology, University of Portsmouth, Portsmouth, Hampshire PO1 2UP, UK.

We report two experiments investigating hindsight bias in children, focusing on a rarely studied age range of 8-13 years. In Experiment 1, we asked children to complete both an auditory hindsight task and a visual hindsight task. Children exhibited hindsight bias in both tasks, and the bias decreased with age. Read More

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January 2022

MANAGEMENT OF ARTERIO-VENOUS FISTULA SIDE BRANCHES DURING MATURATION: LIGATION OR COIL EMBOLIZATION.

Ann Vasc Surg 2022 Jan 17. Epub 2022 Jan 17.

Division of Vascular and Endovascular Surgery; Long School of Medicine, University of Texas Health at San Antonio, San Antonio, Texas. Electronic address:

Objective: Failure of maturation of arteriovenous fistulae (AVF) remains an ongoing concern for dialysis access. One etiology is the presence of side branches which divert flow from the main AVF channel. This study aims to evaluate the outcomes of endovascular and open surgical interventions for AVF side branches in the setting of maturation failure. Read More

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January 2022

Stemless Reverse Total Shoulder Arthroplasty: A Systematic Review.

J Shoulder Elbow Surg 2022 Jan 17. Epub 2022 Jan 17.

Department of Orthopaedic Surgery, Beaumont Health System, Oakland University School of Medicine, Royal Oak, Michigan, USA. Electronic address:

Introduction: Reverse total shoulder arthroplasty and Stemless anatomic total shoulder replacement have been increasing in the United States every year. Stemless humeral components in reverse total shoulder arthroplasty are only approved for clinical trials in the US with an Investigational Device Exception (IDE) with limited data.

Methods: A systematic review was conducted on Stemless Reverse total shoulder arthroplasty according to the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines. Read More

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January 2022

A biomechanical study of the long head of biceps on supraspinatus load and humeral head position during shoulder abduction.

J Shoulder Elbow Surg 2022 Jan 17. Epub 2022 Jan 17.

Department of Anatomy, University of Pretoria, Pretoria, South Africa; Department of Anatomy and Cellular Biology, College of Medicine & Health Sciences, Khalifa University, Abu Dhabi, UAE.

Introduction: The purpose of this study was to determine the effect of biceps tendon tenotomy on the load of the supraspinatus tendon/muscle complex during abduction of the arm from 0-15.

Methods: Eleven fresh frozen human cadaver shoulders (6 males, 5 females, age ranged 44-88 years, mean upper extremity weight 2.96 +0. Read More

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January 2022

Clinical Outcomes Following Open Anterior Shoulder Stabilisation for Glenohumeral Instability In The Young Collision Athlete.

J Shoulder Elbow Surg 2022 Jan 17. Epub 2022 Jan 17.

Unisports Orthopaedics, Auckland, New Zealand.

Background: Anterior glenohumeral instability occurs most commonly in those aged 15 to 29, with 72% of individuals younger than 22 years suffering recurrent episodes; collision athletes are at particular risk. In the setting of subcritical glenoid bone loss, arthroscopic Bankart repair is widely used despite concerns of recurrent dislocations when compared to open techniques. Furthermore, indications for bone-block procedures are evolving with the Latarjet procedure being favored amongst recent authors as a primary stabilization method in elite and contact athletes. Read More

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January 2022