287,653 results match your criteria adults children

Role of ACE2 polymorphism in COVID-19: impact of age.

Clin Chem Lab Med 2021 May 13. Epub 2021 May 13.

Dentofacial Deformities Research Center, Research Institute of Dental Sciences, Shahid Beheshti University of Medical Science, Tehran, Iran.

More than 2 million people have died as a result of the COVID-19 outbreak. Angiotensin-converting enzyme 2 (ACE2) is a counter-regulatory enzyme that converts angiotensin-2 to Ang-(1-7) form in the renin-angiotensin system. Several studies have been analyzed the correlation between ACE2 and COVID-19. Read More

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Blood lead levels and their associated risk factors in Chinese adults from 1980 to 2018.

Ecotoxicol Environ Saf 2021 May 10;218:112294. Epub 2021 May 10.

School of Public Health, Qingdao University, Qingdao 266000, China. Electronic address:

In China, studies on lead exposure to grownup are scarce compared to children, although relevant disease burdens for adults are much severe than that in developed countries. The present study evaluated blood lead levels (BLLs) in Chinese adults by data mining using Monte Carlo simulation. A total of 115 scientific studies published between January 1980 and March 2021 reflecting 45,514 Chinese adults were included in the study. Read More

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Proton beam therapy for children and adolescents and young adults (AYAs): JASTRO and JSPHO Guidelines.

Cancer Treat Rev 2021 Apr 16;98:102209. Epub 2021 Apr 16.

Department of Orthopaedic Oncology, Shizuoka Cancer Center Hospital, Nagaizumi, Shizuoka, Japan.

Children and adolescents and young adults (AYAs) with cancer are often treated with a multidisciplinary approach. This includes use of radiotherapy, which is important for local control, but may also cause adverse events in the long term, including second cancer. The risks for limited growth and development, endocrine dysfunction, reduced fertility and second cancer in children and AYAs are reduced by proton beam therapy (PBT), which has a dose distribution that decreases irradiation of normal organs while still targeting the tumor. Read More

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Smiling Faces on Food Packages Can Increase Adults' Purchase Likelihood for Children.

Appetite 2021 May 10:105301. Epub 2021 May 10.

Courtney Szocs is the Piccadilly Inc., Business Partnership Professor and Assistant Professor of Marketing, Louisiana State University, Baton Rouge, LA 70808. Electronic address:

Manufacturers often include smiling faces on food packages, especially those targeted towards children. Prior research suggests that anthropomorphized images in general, and smiling faces in particular, are an effective marketing tool that encourage food choice and consumption among children. However, it is not clear how adult consumers, who often make food purchases for children, respond to smiling faces on packaging when making decisions for a child recipient. Read More

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Identifying Childhood Expressive Language Features That Best Predict Adult Language and Communication Outcome in Individuals With Autism Spectrum Disorder.

J Speech Lang Hear Res 2021 May 13:1-15. Epub 2021 May 13.

Department of Communication Sciences and Disorders, Emerson College, Boston, MA.

Purpose Several studies have reported that "useful speech" at 5 years of age predicts outcomes in individuals with autism spectrum disorder (ASD), but this skill has been vaguely defined. This study investigates which specific aspects of expressive language in children with ASD best predict adult language and communication outcomes. Method Language samples from 29 children (ages 47-72 months) enrolled in a longitudinal project (e. Read More

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Projected lifetime cancer risk from cone-beam computed tomography for orthodontic treatment.

Korean J Orthod 2021 May;51(3):189-198

Department of Orthodontics, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Objective: To estimate the projected cancer risk attributable to diagnostic cone-beam computed tomography (CBCT) performed under different exposure settings for orthodontic purposes in children and adults.

Methods: We collected a list of CBCT machines and their specifications from 38 orthodontists. Organ doses were estimated using median and maximum exposure settings of 105 kVp/156. Read More

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Promoting Cultural Awareness, Professionalism, and Communication Skills in Medicine through Anatomy: The Deaf Culture Session.

Clin Anat 2021 May 13. Epub 2021 May 13.

College of Education and Human Development, Georgia State University, Atlanta, Georgia.

The anatomy curriculum is a place where professionalism can be learned and practiced, including training in cultural competence and communication skills for working with diverse populations. One population that has received little attention in terms of medical education are d/Deaf and hard of hearing patients, although there is much evidence to support health care disparities in this population. Several major contributing factors include differing views of deafness between medical professionals and those who are culturally Deaf, a lack of understanding of Deaf Culture and American Sign Language (ASL) by medical professionals, a lack of educational resources in ASL, and poor experiences in health care. Read More

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Characteristics of Office-based Physician Visits, 2018.

NCHS Data Brief 2021 May(408):1-8

In 2018, 85% of adults and 96% of children in the United States had a usual place to receive health care (1,2). Most children and adults listed a doctor's office as the usual place they received care (1,2). In 2018, an estimated 860. Read More

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Evaluation of Patient-Reported Outcome Measures of Positive Psychosocial Constructs in Children and Adolescent/Young Adults with Cancer: A Systematic Review of Measurement Properties.

J Adolesc Young Adult Oncol 2021 May 13. Epub 2021 May 13.

Department of Psychiatry and Behavioral Sciences, Oklahoma State University Center for Health Sciences, Tulsa, Oklahoma, USA.

Children, adolescents, and young adults with cancer are a vulnerable population in whom improvements in psycho-oncology care would be valuable. We previously published a scoping review exploring what is known about positive psychological constructs in this population. A key finding was that evidence-based patient-reported outcome measures (PROMs) were needed to standardize psycho-oncology research. Read More

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The education needs of health professionals conservatively managing genital oedema: UK survey findings.

Br J Nurs 2021 May;30(9):S18-S26

National Lymphoedema Research Specialist, Lymphoedema Network Wales.

Background: Adults and children report genital oedema but prevalence is unknown. Pre-registration nurse training rarely includes genital oedema and postgraduate training opportunities are rare.

Aim: To identify the education needs of health professionals regarding management of genital oedema. Read More

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"Web-based, second-best togetherness": Psychosocial group intervention with children of Holocaust survivors during COVID-19.

Irit V Felsen

Am J Orthopsychiatry 2021 ;91(2):171-180

Department of Psychology, Columbia University.

Evidence from multiple samples of trauma-exposed populations across the globe suggests that intergenerational trauma constitutes a biopsychological risk factor which manifests itself throughout the life cycle of offspring of trauma survivors. Prior empirical studies have shown that adult children of Holocaust survivors (OHS, also referred to in select quotes as 2G for "Second Generation") are vulnerable to life-threatening situations. This study aimed to examine the reactions of OHS to the COVID-19 pandemic, which posed a serious threat to the lives of many, in particular to older adults. Read More

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January 2021

Can laboratory findings predict pulmonary involvement in children with COVID-19 infection?

Pediatr Pulmonol 2021 May 13. Epub 2021 May 13.

Department of Pediatric Infectious Diseases, University of Health Sciences Dr. Behçet Uz Child Disease and Pediatric Surgery Training and Research Hospital, İzmir, Turkey.

Background: Studies investigating clinical and imaging findings of coronavirus disease 2019 (COVID-19) pneumonia and predictors for lung injury mostly focus on adults. In this study, we aimed to evaluate the role of laboratory findings in predicting lung involvement in children with COVID-19.

Methods: Children with COVID-19 confirmed by reverse-transcription polymerase chain reaction or COVID-19 IgM and who underwent chest computed tomography (CT) scans were reviewed retrospectively. Read More

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A National Comparative Investigation of Twins With Congenital Heart Defects for Neurodevelopmental Outcomes and Quality of Life (Same Same, but Different?): Protocol for a Prospective Observational Study.

JMIR Res Protoc 2021 May 13;10(5):e26404. Epub 2021 May 13.

Department of Congenital Heart Defects and Pediatric Cardiology, German Heart Center of Munich, Munich, Germany.

Background: Due to the increased survival rates of patients with congenital heart defects (CHD), associated disorders are an increasing focus of research. Existing studies figured out an association between CHD and its treatment, and neurodevelopmental outcomes including motor competence impairments. All these studies, however, compared their test results with reference values or results of healthy control groups. Read More

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Recent perspective on cow's milk allergy and dairy nutrition.

Crit Rev Food Sci Nutr 2021 May 13:1-16. Epub 2021 May 13.

Department of Animal Sciences, North Carolina Agricultural and Technical State University, Greensboro, North Carolina, USA.

Cow's milk is a highly nutritious biological fluid that provides nourishment and immunity to infants when breastfeeding declines. However, some infants, children, and adults are allergic to cow's milk because milk contains potential allergens in the form of proteins. Casein and whey proteins and their coagulated sub-fractions in the milk such as S-casein, S-casein, -casein, -casein and -lactalbumin, -lactoglobulin, bovine serum albumin, immunoglobulins, lactoferrin, respectively are the major etiological determinant of cow's milk allergy (CMA). Read More

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ACG Clinical Report and Recommendations on Transition of Care in Children and Adolescents With Hereditary Polyposis Syndromes.

Am J Gastroenterol 2021 Apr;116(4):638-646

1Division of Gastroenterology, Hepatology and Nutrition, Children's Mercy Hospital, Kansas City, MO, USA; 2University of Missouri-Kansas City School of Medicine, Kansas City, MO, USA; 3Department of Gastroenterology, Hepatology and Nutrition, Digestive Disease and Surgery Institute, Cleveland Clinic, Cleveland, OH, USA; 4St Mark's Hospital Polyposis Registry, Harrow, United Kingdom; 5Division of Gastroenterology, Hepatology and Nutrition, The Hospital for Sick Children and the Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, University of Toronto, Toronto, Canada; 6Center for Behavioral Health, Neurological Institute, Cleveland Clinic, Cleveland OH, USA; 7Department of Colorectal Surgery, Digestive Disease and Surgery Institute, Cleveland Clinic, Cleveland, OH, USA; 8Dana-Dwek Children's Hospital, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Transition of care (TOC) in adolescents and young adults (AYAs) with chronic gastrointestinal disorders has received increased attention, especially in those with inflammatory bowel disease. AYAs with hereditary polyposis syndromes are a heterogeneous group of patients with overlapping and complex medical needs. These patients are particularly vulnerable because of the risk of loss of continuity of care and subsequent poor disease outcomes. Read More

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Communication in dyads of adult children at the end of life with their parents and parents at the end of life with their adult children: findings from a mixed-methods study.

Psychooncology 2021 May 13. Epub 2021 May 13.

Institute for General Practice, Hannover Medical School, Hannover, Germany.

Objective: Patient-family member communication plays a decisive role in coping with an end-of-life situation and is strongly influenced by the dyadic relationship. There is a lack of research exploring and comparing the specifics of communication between: 1) terminally ill adult children and their parents and 2) terminally ill parents and their adult children. The present study aimed at describing and comparing communication specifics within these two dyads. Read More

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SKILLS - A psychoeducational group programme for children with ADHD.

Scand J Psychol 2021 May 13. Epub 2021 May 13.

Department of Neuroscience, Child and Adolescent Psychiatry Unit, Uppsala University, Uppsala, Sweden.

Psychoeducation is regarded as a first line of intervention for attention-deficit/hyperactivity disorder (ADHD). Previous studies have been limited to psychoeducation for adult patients or parents of children with ADHD. Therefore, the aim of the present study was to investigate the acceptability and effectiveness of a psychoeducational group intervention for children with ADHD. Read More

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Severe abrupt (thunderclap) non-traumatic headache at the pediatric emergency department - a retrospective study.

Cephalalgia 2021 May 13:3331024211014612. Epub 2021 May 13.

Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Background: Adult abrupt severe non-traumatic headache (thunderclap) is often related to serious underlying etiologies such as subarachnoid hemorrhage. However, data are sparse regarding thunderclap headache in the pediatric population.

Objective: The aim of the study was to evaluate the prevalence, characteristics and causes of thunderclap headache in the pediatric and adolescent population, aged 6-18 years, presenting to a pediatric emergency department. Read More

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Are body surface area (BSA) based estimates of liver volume applicable to children with overweight or obesity? An in-vivo validation study.

Clin Transl Sci 2021 May 13. Epub 2021 May 13.

Children's Mercy Kansas City, Kansas City.

The liver is the primary organ responsible for clearing most drugs from the body and thus determines systemic drug concentrations over time. Drug clearance by the liver appears to be directly related to organ size. In children, organ size changes as children age and grow. Read More

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Orthographic depth and developmental dyslexia: a meta-analytic study.

Ann Dyslexia 2021 May 12. Epub 2021 May 12.

DISTUM, Department of Humanities, University of Urbino Carlo Bo, Urbino, Italy.

Cross-cultural studies have suggested that reading deficits in developmental dyslexia (DD) can be moderated by orthographic depth. To further explore this issue and assess the moderating role of orthographic depth in the developmental cognitive trajectories of dyslexic and typical readers, we systematically reviewed 113 studies on DD that were published from 2013 to 2018 and selected 79 in which participants received an official DD diagnosis. Each study was classified according to orthographic depth (deep vs. Read More

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Trace element-based geochemical contamination characteristics and potential risks to human health: a case study from Northeast Turkey.

Environ Geochem Health 2021 May 13. Epub 2021 May 13.

Çekmece Nuclear Research and Training Center, Yarımburgaz Mah, 34303, Halkalı İstanbul, Turkey.

Trace elements measured in Artvin province soil samples in Northeast Turkey were assessed using pollution and health indices. The study area is positioned in one of the essential metallogenic belts in Turkey. This attempt is the first endeavor toward the study area in this context. Read More

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Knowing How to Fold 'em: Paper Folding across Early Childhood.

J Mot Learn Dev 2018 Jun;6(1):147-166

University of Wisconsin-Madison.

Folding paper is a seemingly simple act that requires planning, bimanual coordination, and manual strength and control to produce specific forces. Although paper folding has been used as an assessment tool and as a way to promote spatial skills, this study represents the first attempt to document when paper folding emerges across early childhood. Seventy-seven children (ages 18 months to 7 years) and an adult reference group (24 college-aged adults) completed three pre-specified folds on a single piece of paper. Read More

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Impact of SARS-CoV-2 Pandemic and Strategies for Resumption of Activities During the Second Wave of the Pandemic: A Report From Eight Paediatric Hospitals From the ECHO Network.

Front Public Health 2021 26;9:630168. Epub 2021 Apr 26.

Meyer Children's Hospital, Firenze, Italy.

The Severe Acute Respiratory Syndrome CoronaVirus type 2 (SARS-CoV-2) pandemic impacted the organization of paediatric hospitals. This study aimed to evaluate the preparedness for the pandemic among a European network of children's hospitals and to explore the strategies to restart health care services. A cross-sectional, web-based survey was distributed in May 2020 to the 13 children's tertiary care hospitals belonging to the European Children's Hospitals Organisation. Read More

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A Recombinant BCG Vaccine Is Safe and Immunogenic in Neonatal Calves and Reduces the Clinical Disease Caused by the Respiratory Syncytial Virus.

Front Immunol 2021 26;12:664212. Epub 2021 Apr 26.

Department of Veterinary Microbiology and Preventative Medicine, Iowa State University, Ames, IA, United States.

The human respiratory syncytial virus (hRSV) constitutes a major health burden, causing millions of hospitalizations in children under five years old worldwide due to acute lower respiratory tract infections. Despite decades of research, licensed vaccines to prevent hRSV are not available. Development of vaccines against hRSV targeting young infants requires ruling out potential vaccine-enhanced disease presentations. Read More

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Biological Therapies in Children and Adolescents with Severe Uncontrolled Asthma: A Practical Review.

Biologics 2021 5;15:133-142. Epub 2021 May 5.

Pediatric Clinic, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.

Severe uncontrolled asthma is a complex and heterogeneous disease. A multidisciplinary assessment is required to correctly identify and manage children and adolescents with severe asthma because they may require strict monitoring and additional treatment with advanced targeted therapies. Recent research efforts have focused on identifying epidemiologic, clinical, and molecular mechanisms that underlie severe asthma, leading to the recognition of different phenotypes and endotypes and identifying biomarkers able to predict the response to biologic therapies. Read More

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A Case of Acute Gonococcal Conjunctivitis in an Unusual Age Group.

Nepal J Ophthalmol 2021 Jan;13(25):137-140

Tilganga Institute of Ophthalmology, Nepal.

Introduction: This is a case of case of acute gonococcal conjunctivitis in a 2.5 years old female child.

Case: A 2. Read More

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January 2021

Association between parents' socioeconomic conditions and nutritional status during childhood and the risk of cardiovascular disease in their adult offspring: an intergenerational study in south India.

J Epidemiol Community Health 2021 May 12. Epub 2021 May 12.

Department of Non-Communicable Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, UK.

Background: Some researchers have suggested that parents' exposure to poor socioeconomic conditions during childhood can increase their offspring's risk of cardiovascular disease, primarily through poor maternal nutrition and growth. However, epidemiological data on this association are limited. In an intergenerational cohort from rural India, we examined the association of parental childhood socioeconomic conditions and stature with offspring's cardiovascular risk, hypothesising an inverse association between the two. Read More

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The measurement properties of tests and tools used in cystic fibrosis studies: a systematic review.

Eur Respir Rev 2021 Jun 11;30(160). Epub 2021 May 11.

Sydney School of Public Health, The University of Sydney, Sydney, Australia.

There is no consensus on how best to measure responses to interventions among children and adults with cystic fibrosis (CF). We have systematically reviewed and summarised the characteristics and measurement properties of tests and tools that have been used to capture outcomes in studies among people with CF, including their reliability, validity and responsiveness. This review is intended to guide researchers when selecting tests or tools for measuring treatment effects in CF trials. Read More

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Long-Term Care of the Pediatric Kidney Transplant Recipient.

Clin J Am Soc Nephrol 2021 May 12. Epub 2021 May 12.

Department of Pediatrics, McGill University, Montreal, Quebec, Canada

Pediatric kidney transplant recipients are distinguished from adult recipients by the need for many decades of graft function, the potential effect of CKD on neurodevelopment, and the changing immune environment of a developing human. The entire life of an individual who receives a transplant as a child is colored by their status as a transplant recipient. Not only must these young recipients negotiate all of the usual challenges of emerging adulthood (transition from school to work, romantic relationships, achieving independence from parents), but they must learn to manage a life-threatening medical condition independently. Read More

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