26,587 results match your criteria admitted icu


Predictive Value of the Methicillin-Resistant Nasal Swab for Methicillin-Resistant Ventilator-Associated Pneumonia in the Trauma Patient.

Surg Infect (Larchmt) 2021 Apr 19. Epub 2021 Apr 19.

Department of Section of Acute Care Surgery, Department of Surgery, Inova Fairfax Medical Campus, Falls Church, Virginia, USA.

Many trauma centers have empiric treatment algorithms for ventilator-associated pneumonia (VAP) treatment prior to culture results that include antibiotic agents for methicillin-resistant (MRSA) coverage that can have adverse effects. This is the only study to evaluate risk factors and MRSA nasal swabs to risk-stratify trauma patients for MRSA VAP, thereby potentially limiting the need for empiric vancomycin. This was a single institution retrospective cohort study. Read More

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Case Report of Two Patients With COVID-19 and Sacral Pressure Injuries Associated with Pyoderma Gangrenosum.

Adv Skin Wound Care 2021 Apr 16. Epub 2021 Apr 16.

In the Department of Plastic and Reconstructive Surgery, University Hospital Brussels, Belgium, Rania Elkhatib, MD, is Attending Physician; Gabriele Giunta, MD, FEBOPRAS, is Consultant; Valerie Hanssens, MSc, is Nurse Specialist; Ayush Kapila, MD, MRCS, is Resident; Randy De Baerdemaeker, MD, FEBOPRAS, is Consultant; Assaf Zeltzer, MD, PhD, is Consultant; and Moustapha Hamdi, MD, PhD, is Head of Department. The authors have disclosed no financial relationships related to this article. Submitted September 2, 2020; accepted in revised form October 28, 2020.

Abstract: With the continuous spread of the COVID-19 pandemic, an increasing number of patients have been admitted to the ICU with severe respiratory complications requing prolonged supine positioning. Recently, many case reports have been published regarding dermatological manifestations associated with the COVID-19 disease. Yet, there is little information about the clinical features. Read More

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The Impact of Earplugs and Eye Masks on Sleep Quality in Surgical ICU Patients at Risk for Frequent Awakenings.

Crit Care Med 2021 Apr 16. Epub 2021 Apr 16.

Department of Anesthesiology, University of Texas Southwestern Medical Center, Dallas, TX. Department of Anesthesiology, University of California - Irvine, Orange, CA. University of Texas Southwestern Medical Center, Dallas, TX. Department of Biostatistics and Data Sciences, University of Texas Southwestern Medical Center, Dallas, TX.

Objectives: Sleep disturbances may contribute to the development of delirium, prolonged ICU stay, and increased mortality. There is conflicting data on the effectiveness of earplugs and eye masks for sleep promotion in the ICU. This study evaluates the impact of earplugs and eye masks on sleep quality in postoperative surgical ICU patients at risk for frequent awakenings. Read More

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Pediatric Acute Alcohol Intoxication Admitted to the ICU: A Review of 102 Cases in France.

Crit Care Med 2021 Apr 19. Epub 2021 Apr 19.

Paediatric Intensive Care Unit, Kremlin Bicêtre University Hospital, AP-HP, Paris, France. Intensive Care Department, Grand Hôpital de l'Est Francilien, Jossigny Hospital, Marne la Vallée, France. Pediatric Intensive Care Department, Lyon University Hospital, Lyon, France. Intensive Care Department, Lariboisière University Hospital, AP-HP, Paris, France. Intensive Care Department, Lariboisière University Hospital, APHP, Paris, France. Pediatric Intensive Care Unit, Robert Debré University Hospital, AP-HP, Paris, France. Pediatric Intensive Care Unit, University Hospital, Lille, France. Pediatric Intensive Care Department, Hôpital Jeanne de Flandre, University Hospital, Lille, France. Intensive Care Department, Cochin University Hospital, AP-HP, Paris, France. Intensive Care Department, Cochin University Hospital, APHP, Paris, France. Pediatric Intensive Care Unit, Raymond Poincaré University Hospital, AP-HP, Garches, France.

Objectives: To describe the profile and clinical outcomes of children (<18 yr) admitted to intensive care for acute alcohol intoxication, with special attention to complications and to the subgroup that required intubation.

Design: Retrospective observational study.

Setting: Seven pediatric and three adult ICUs in France. Read More

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The Effects of Body Mass Index and Seatbelt Use on Pediatric Chest and Abdominal Injuries after Motor Vehicle Collisions.

Am Surg 2021 Apr 18:31348211011106. Epub 2021 Apr 18.

Department of Surgery, Division of Trauma and Surgical Critical Care, 14506Kendall Regional Medical Center, Miami, FL, USA.

Background: Motor vehicle collisions (MVCs) are a major cause of pediatric morbidity and mortality. However, the effect of body mass index (BMI) and seatbelt use on thoracic injuries and outcomes in pediatric patients with rib fractures remains unexplored. We aim to assess how seatbelt use and BMI affect thoracic injuries and outcomes in pediatric patients who sustained ≥3 rib fractures following an MVC. Read More

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Trends in mortality of hospitalised COVID-19 patients: A single centre observational cohort study from Spain.

Lancet Reg Health Eur 2021 Apr 24;3:100041. Epub 2021 Jan 24.

Department of Infectious Diseases, Hospital Clinic of Barcelona-IDIBAPS, University of Barcelona, C/ Villarroel 170, 08036 Barcelona, Spain.

Background: We aimed to describe changes in characteristics and treatment strategies of hospitalised patients with COVID-19 and detail the mortality trend over time.

Methods: Observational cohort study of all consecutive patients admitted ≥ 48 h to Hospital Clinic of Barcelona for COVID-19 (1 March-30 September 2020).

Findings: A total of 1645 consecutive patients with COVID-19 were assessed over a 7-month period. Read More

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Management of maternal COVID-19: considerations for anesthesiologists.

Curr Opin Anaesthesiol 2021 Apr 16. Epub 2021 Apr 16.

Department of Anesthesiology, Columbia University Irving Medical Center, New York, New York, USA.

Purpose Of Review: To describe updates to pragmatic recommendations that were published during the first coronavirus disease 2019 (COVID-19) surge, including the current thinking about whether pregnancy worsens the severity of COVID-19.

Recent Findings: Although a majority of pregnant women infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remain asymptomatic or paucisymptomatic, pregnancy puts women at higher risk of severe COVID-19 and adverse birth outcomes. Pregnant and recently pregnant women are more likely to be admitted to intensive care units and receive mechanical ventilation than nonpregnant patients with COVID-19, although preexisting maternal comorbidities are significant risk factors. Read More

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[Improve of efficiency of patients management admitted in an Intermediate Respiratory Care Unit by means of an integrated delivery of health care].

J Healthc Qual Res 2021 Apr 15. Epub 2021 Apr 15.

Unidad de Sueño, Servicio de Neumología, Hospital Universitario Sagrat Cor; Quirón Salud, Barcelona, España.

Introduction: Patients admitted to Intermediate Respiratory Care Units are common sharpeners. We describe their overall improvement by the introduction of an Integrated Care Process.

Methods: We conducted an observational descriptive study based on an Intermediate Respiratory Care Unit during 2015-2017. Read More

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Thirdhand smoke associations with the gut microbiomes of infants admitted to a neonatal intensive care unit: An observational study.

Environ Res 2021 Apr 15:111180. Epub 2021 Apr 15.

Translational and Clinical Research Institute, Newcastle University, Medical School, Framlington Place, Newcastle, NE2 4HH. Electronic address:

Introduction: Microbiome differences have been found in adults who smoke cigarettes compared to non-smoking adults, but the impact of thirdhand smoke (THS; post-combustion tobacco residue) on hospitalized infants' rapidly developing gut microbiomes is unexplored. Our aim was to explore gut microbiome differences in infants admitted to a neonatal ICU (NICU) with varying THS-related exposure.

Methods: Forty-three mother-infant dyads (household member[s] smoke cigarettes, n=32; no household smoking, n=11) consented to a carbon monoxide-breath sample, bedside furniture nicotine wipes, infant-urine samples (for cotinine [nicotine's primary metabolite] assays), and stool collection (for 16S rRNA V4 gene sequencing). Read More

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Severe pneumonia caused by Parvimonas micra: a case report.

BMC Infect Dis 2021 Apr 17;21(1):364. Epub 2021 Apr 17.

Department of Intense Care Unit, Shenzhen Longhua Central Hospital, Guanlan Boulevard, Shenzhen, 187, China.

Background: Parvimonas micra (P. micra) is a gram-positive anaerobic coccus that is detected widely on the skin, in the oral mucosa and in the gastrointestinal tract. In certain circumstances, P. Read More

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Intermediate vs Standard-dose Prophylactic Anticoagulation in Patients with COVID-19 Admitted to ICU: Ninety-day Results from the INSPIRATION Trial.

Thromb Haemost 2021 Apr 17. Epub 2021 Apr 17.

Rajaie Cardiovascular Medical and Research Center, Tehran, Iran (the Islamic Republic of).

Background: Thrombotic complications are considered among the main extrapulmonary manifestations of COVID-19. The optimal type and duration of prophylactic antithrombotic therapy in these patients remain unknown.

Methods: This manuscript reports the final (90-day) results of the Intermediate versus Standard-dose Prophylactic anticoagulation In cRitically-ill pATIents with COVID-19: An opeN label randomized controlled trial (INSPIRATION) study. Read More

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Abdominal Computed Tomography Angiography and Venography in Evaluation of Hemorrhagic and Thrombotic lesions in Hospitalized COVID-19 patients.

Clin Imaging 2021 Apr 14;79:12-19. Epub 2021 Apr 14.

Diagnostic and Interventional Radiology Department, Alexandria Faculty of Medicine, Shamplion Street, Alexandria 21131, Egypt. Electronic address:

Purpose: To report imaging findings at computed tomography angiography (CTA) and venography (CTV) of the abdomen and pelvis in evaluation of hemorrhagic and thrombotic lesions in hospitalized patients with COVID-19.

Methods: In this retrospective observational study, patients admitted to a single tertiary care center from April 1 to July 20, 2020, who tested positive for SARS-CoV-2 and developed acute abdominal pain or decreasing hemoglobin levels over the course of hospitalization were included. Abdominal CTA/CTV imaging studies performed in these patients were reviewed, and acute hemorrhagic or thromboembolic findings were recorded. Read More

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Low COVID-19 mortality in Spanish children.

Lancet Child Adolesc Health 2021 Apr 14. Epub 2021 Apr 14.

Paediatrics, Infectious and Tropical Diseases Department, Hospital Universitario La Paz, Instituto Investigación Hospital La Paz (IDIPaz), Madrid, Spain.

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New-onset atrial fibrillation in the intensive care unit: protocol for an international inception cohort study (AFIB-ICU).

Acta Anaesthesiol Scand 2021 Apr 17. Epub 2021 Apr 17.

Department of Intensive Care, University of Copenhagen, Copenhagen, Denmark.

Introduction: New-onset atrial fibrillation (NOAF) is frequently observed in critically ill patients and may be associated with prolonged hospital stay and increased mortality. Considerable variation exists in the reported frequencies of NOAF due to the lack of a standardised definition and detection method. Importantly, there are limited data on NOAF in the intensive care unit (ICU). Read More

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Lesson by SARS-CoV-2 disease (COVID-19): whole-body CT angiography detection of "relevant" and "other/incidental" systemic vascular findings.

Eur Radiol 2021 Apr 16. Epub 2021 Apr 16.

Section of Respiratory Diseases, Department of Clinical Medicine and Surgery, Federico II University of Naples, Naples, Italy.

Objectives: Increasing evidence suggests that SARS-CoV-2 infection may lead to severe and multi-site vascular involvement. Our study aimed at assessing the frequency of vascular and extravascular events' distribution in a retrospective cohort of 42 COVID-19 patients.

Methods: Patients were evaluated by whole-body CT angiography between March 16 and April 30, 2020. Read More

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Incidence and factors associated with delirium in children in a single pediatric intensive care unit in Brazil.

J Pediatr Nurs 2021 Apr 13. Epub 2021 Apr 13.

Pediatric Nursing Department, Escola Paulista de Enfermagem, Universidade Federal de São Paulo, Brazil. Electronic address:

Purpose: To identify the incidence of delirium in a Pediatric Intensive Care Unit (PICU); to determine the factors associated with the occurrence of delirium and the agreement between two scales used for detection of pediatric delirium in critically ill children.

Designs And Method: Descriptive longitudinal study carried out in a PICU. The sample consisted of 65 critically ill children admitted to the PICU, with more than 24 h of hospitalization, excluding children with neurological or cognitive impairment, hearing and visual impairment, chronic encephalopathy and declining consent to participate in the study. Read More

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[Prevalence of Arterial Hypertension in a neonatal intensive care unit].

Rev Chil Pediatr 2020 Dec 8;91(6):891-898. Epub 2020 Oct 8.

Hospital General de Niños Pedro de Elizalde, Ciudad Autónoma de Buenos Aires, Argentina.

Introduction: The prevalence of neonatal hypertension in neonatal intensive care units (NICU) ranges between 3 and 9%. However, there is no current data on Latin America.

Objective: To estimate the prevalence of neonatal hypertension and to assess its association with causes previously related to this condi tion. Read More

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December 2020

Coronavirus Disease 2019 ICU Patients Have Higher-Than-Expected Acute Physiology and Chronic Health Evaluation-Adjusted Mortality and Length of Stay Than Viral Pneumonia ICU Patients.

Crit Care Med 2021 Apr 2. Epub 2021 Apr 2.

1 Center for Case Management, Natick, MA. 2 Division of Pulmonary and Critical Care Medicine, Baystate Medical Center, Springfield, MA. 3 Department of Anesthesiology, University of Massachusetts Medical School-Baystate, Springfield, MA. 4 Cerner Corporation, Kansas City, MO.

Objectives: To compare Acute Physiology and Chronic Health Evaluation-IV-adjusted mortality and length of stay outcomes of adult ICU patients who tested positive for coronavirus disease 2019 with patients admitted to ICU with other viral pneumonias including a subgroup with viral pneumonia and concurrent acute respiratory distress syndrome (viral pneumonia-acute respiratory distress syndrome).

Design: Retrospective review of Acute Physiology and Chronic Health Evaluation data collected from routine clinical care.

Setting: Forty-three hospitals contributing coronavirus disease 2019 patient data between March 14, and June 17, 2020, and 132 hospitals in the United States contributing data on viral pneumonia patients to the Acute Physiology and Chronic Health Evaluation database between January 1, 2014, and December 31, 2019. Read More

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Outcomes and Safety of Early Percutaneous Tracheostomy in Coronavirus Disease 2019 Patients Admitted to the ICU.

Crit Care Med 2021 Apr 2. Epub 2021 Apr 2.

1 Department of Hospital Medicine, Covenant Health System, Knoxville, TN 2 Department of Pulmonary and Critical Care Medicine, Maimonides Medical Center, Brooklyn, NY.

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Surge and Mortality in ICUs in New York City's Public Healthcare System.

Crit Care Med 2021 Apr 5. Epub 2021 Apr 5.

1 Division of Pulmonary, Critical Care, and Sleep Medicine, New York University School of Medicine, Bellevue Hospital, New York, NY. 2 Office of Population Health, NYC Health + Hospitals, New York, NY. 3 Division of Infectious Diseases and Immunology, NYU Grossman School of Medicine, Bellevue Hospital, New York, NY. 4 Department of Nursing, NYC Health + Hospitals Queens, New York, NY. 5 Data & Analytics (DnA)-Epic Reporting Team, NYC Health + Hospitals, New York, NY.

Objectives: To evaluate the impact of ICU surge on mortality and to explore clinical and sociodemographic predictors of mortality.

Design: Retrospective cohort analysis.

Setting: NYC Health + Hospitals ICUs. Read More

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Protective Effects of Intravenous Magnesium Sulfate in Stroke Patients Receiving Amiodarone: A Randomized Controlled Trial.

Adv Exp Med Biol 2021 ;1308:579-588

Applied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Anti-arrhythmic agents, like amiodarone, interfere at different stages of the ischemic stroke. However, amiodarone was accompanied with immunological pulmonary complications and adverse neurological effects. We hypothesize that magnesium sulfate in combination with amiodarone holds promise for stroke treatment. Read More

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January 2021

Co-infection in critically ill patients with COVID-19: an observational cohort study from England.

J Med Microbiol 2021 Apr;70(4)

NIHR Nottingham Biomedical Research Centre, Queen's Medical Centre, Nottingham NG7 2UH, UK.

During previous viral pandemics, reported co-infection rates and implicated pathogens have varied. In the 1918 influenza pandemic, a large proportion of severe illness and death was complicated by bacterial co-infection, predominantly and . A better understanding of the incidence of co-infection in patients with COVID-19 infection and the pathogens involved is necessary for effective antimicrobial stewardship. Read More

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How often and to what extent do admitted COVID-19 patients have signs of cardiac injury?

Neth Heart J 2021 Apr 16. Epub 2021 Apr 16.

Department of Cardiology, Maasstad Hospital, Rotterdam, The Netherlands.

Background: COVID-19 can cause myocardial injury in a significant proportion of patients admitted to the hospital and seems to be associated with worse prognosis. The aim of this review was to study how often and to what extent COVID-19 causes myocardial injury and whether this is an important contributor to outcome with implications for management.

Methods: A literature search was performed in Medline and Embase. Read More

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The effect of the underlying malignancy on short- and medium-term survival of critically ill patients admitted to the intensive care unit: a retrospective analysis based on propensity score matching.

BMC Cancer 2021 Apr 15;21(1):417. Epub 2021 Apr 15.

Department of Intensive Care Unit, National Cancer Center / National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100021, China.

Background: Advances in oncology led to a substantial increase in the number of patients requiring admission to the ICU. It is significant to confirm which cancer critical patients can benefit from the ICU care like noncancer patients.

Methods: An observational retrospective cohort study using intensive care unit (ICU) admissions of Medical Information Mart for Intensive Care III from the Beth Israel Deaconess Medical Center in Boston, MA, USA between 2001 and 2012 was conducted. Read More

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Bronchoalveolar lavage fluid characteristics and outcomes of invasively mechanically ventilated patients with COVID-19 pneumonia in Genoa, Italy.

BMC Infect Dis 2021 Apr 15;21(1):353. Epub 2021 Apr 15.

Infectious Diseases Unit, San Martino Policlinico Hospital - IRCCS for Oncology and Neurosciences, Genoa, Italy.

Background: The primary objective of the study is to describe the cellular characteristics of bronchoalveolar lavage fluid (BALF) of COVID-19 patients requiring invasive mechanical ventilation; the secondary outcome is to describe BALF findings between survivors vs non-survivors.

Materials And Methods: Patients positive for SARS-CoV-2 RT PCR, admitted to ICU between March and April 2020 were enrolled. At ICU admission, BALF were analyzed by flow cytometry. Read More

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Antiretroviral Therapy Management in Adults With HIV During ICU Admission.

J Pharm Pract 2021 Apr 16:8971900211000692. Epub 2021 Apr 16.

8452Southwestern Oklahoma State University College of Pharmacy, Weatherford, OK, USA.

The extended lifespan of people living with human immunodeficiency (HIV) and acquired immune deficiency syndrome (AIDS) (PLWHA) has increased the potential for ICU admissions unrelated to HIV infection. The objective of this review is to guide continued management of antiretroviral therapy (ART) recommended by the United States Department of Health and Human Services Antiretroviral Guidelines in critically ill adult PLWHA admitted to the intensive care unit (ICU). Pharmacists are uniquely positioned to mitigate these concerns, including whether to continue ART in the ICU, drug interactions with common ICU drugs, renal and hepatic dosing considerations, and alternative methods of administration. Read More

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Hospital-acquired infections in critically-ill COVID-19 patients.

Chest 2021 Apr 12. Epub 2021 Apr 12.

Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy; Infectious Diseases Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Background: Few small studies have described hospital-acquired infections (HAIs) during COVID-19.

Research Question: What patient characteristics in critically ill patients with COVID-19 are associated with HAIs and how do HAIs associate with outcomes in these patients?

Study Design And Methods: Multicenter retrospective analysis of prospectively collected data including adult patients with severe COVID-19, admitted to 8 Italian hub hospitals from February 20, 2020, to May 20, 2020. Descriptive statistics, univariable and multivariable Weibull regression models were used to assess incidence, microbial etiology, resistance patterns, risk factors (i. Read More

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Central Venous Catheter Adverse Events Are not Associated with Crowding Indicators.

West J Emerg Med 2021 Jan 20;22(2):427-434. Epub 2021 Jan 20.

Washington University School of Medicine, Department of Emergency Medicine, St. Louis, Missouri.

Objective: Crowding in the emergency department (ED) impacts a number of important quality and safety metrics. We studied ED crowding measures associated with adverse events (AE) resulting from central venous catheters (CVC) inserted in the ED, as well as the relationship between crowding and the frequency of CVC insertions in an ED cohort admitted to the intensive care unit (ICU).

Methods: We conducted a retrospective observational study from 2008-2010 in an academic tertiary care center. Read More

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January 2021

Transfer of Patients with Spontaneous Intracranial Hemorrhage who Need External Ventricular Drain: Does Admission Location Matter?

West J Emerg Med 2021 Jan 12;22(2):379-388. Epub 2021 Jan 12.

University of Maryland School of Medicine, The R. Adams Cowley Shock Trauma Center, Baltimore, Maryland.

Introduction: Patients with spontaneous intracranial hemorrhage (sICH) are associated with high mortality and require early neurosurgical interventions. At our academic referral center, the neurocritical care unit (NCCU) receives patients directly from referring facilities. However, when no NCCU bed is immediately available, patients are initially admitted to the critical care resuscitation unit (CCRU). Read More

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January 2021

Impact of cancer history on outcomes among hospitalized COVID-19 patients.

Oncologist 2021 Apr 15. Epub 2021 Apr 15.

Dana-Farber Cancer Institute, Boston, MA.

Background: Early reports suggested increased mortality from COVID-19 in patients with cancer but lacked rigorous comparisons to non-cancer patients. We investigated whether a current cancer diagnosis or cancer history is an independent risk factor for death in hospitalized COVID-19 patients.

Patients And Methods: We identified patients with a history of cancer admitted to 2 large hospitals between 3/13/2020 and 5/10/2020 with laboratory-confirmed COVID-19 and matched them 1:2 to patients without a history of cancer. Read More

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