Sex Transm Dis 2021 Jul 17. Epub 2021 Jul 17.
Division of Epidemiology, Vanderbilt University Medical Center, Nashville, TN, USA Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA Center for AIDS Intervention Research, Medical College of Wisconsin, Milwaukee, WI, USA Center for Immunization and Infection Research in Cancer, Moffitt Cancer Center & Research Institute, Tampa, FL, USA Centro de Referência e Treinamento DST/AIDS and Centro Universitário FAM, São Paulo, Brazil Instituto do Cancer do Estado de São Paulo, Faculdade de Medicina FMUSP, Universidade de São Paulo, São Paulo, Brazil Instituto Nacional de Salud Pública, Cuernavaca, México.
Background: Studies in women have shown an increased risk of HIV acquisition with prior HPV infection; however, few studies have been conducted among men. Our objective was to assess whether HPV-related external genital lesions (EGLs) increase risk of HIV seroconversion among men.
Methods: A total of 1379 HIV-negative men aged 18-70 years from the US, Mexico, and Brazil were followed for up to seven years and underwent clinical examination for EGLs and blood draws every six-months. Read More