Europace 2014 Nov;16 Suppl 4:iv3-iv10
Department of Bioengineering, University of California San Diego, Mail Code 0412, 9500 Gilman Drive, La Jolla, CA 92093-0412, USA Department of Medicine, University of California San Diego, La Jolla, CA, USA Cardiac Biomedical Science and Engineering Center, University of California San Diego, CA, USA
Aims: The aim of this study was to investigate structural contributions to the maintenance of rotors in human atrial fibrillation (AF) and possible mechanisms of termination.
Methods And Results: A three-dimensional human biatrial finite element model based on patient-derived computed tomography and arrhythmia observed at electrophysiology study was used to study AF. With normal physiological electrical conductivity and effective refractory periods (ERPs), wave break failed to sustain reentrant activity or electrical rotors. Read More