42,354 results match your criteria adhd


Neuropsychological and real-life functioning of adults with ADHD.

J Neural Transm (Vienna) 2021 Jun 12. Epub 2021 Jun 12.

Department of Clinical and Developmental Neuropsychology, Faculty of Behavioral and Social Sciences, University of Groningen, 9712 TS, Groningen, The Netherlands.

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Balanced Growth project: a protocol of a single-centre observational study on the involvement of the vestibular system in a child's motor and cognitive development.

BMJ Open 2021 Jun 11;11(6):e049165. Epub 2021 Jun 11.

Department of Rehabilitation Sciences, Ghent University Faculty of Medicine and Health Sciences, Ghent, Belgium.

Introduction: The involvement of the vestibular system in the motor and higher (cognitive) performances of typically developing or vestibular-impaired children is currently unknown or has only scarcely been explored. Interestingly, arguments for an interaction between vestibular, motor and cognitive functions in children can also be supported by research on children known for their difficulties in motor and/or cognitive processing (eg, children with neurodevelopmental disorders (NDD)), as they often present with vestibular-like characteristics. Therefore, in order to elucidate this interaction, and to increase the understanding of the pathophysiology and symptomatology of vestibular disorders and NDD in children, the Balanced Growth project was developed. Read More

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Review: Adult Outcome as Seen Through Controlled Prospective Follow-up Studies of Children With Attention-Deficit/Hyperactivity Disorder Followed Into Adulthood.

J Am Acad Child Adolesc Psychiatry 2021 Jun 5. Epub 2021 Jun 5.

McGill University Health Center, Montreal, Quebec, Canada; Division of Child Psychiatry, McGill University, Montreal Children's Hospital, McGill University Health Center, Montreal, Quebec, Canada. Electronic address:

Objective: To describe adult outcome of people with childhood diagnosed attention-deficit/hyperactivity disorder (ADHD) and its several key predictors via a review of seven North American controlled prospective follow-up studies: the Montreal, New York, Milwaukee, Pittsburgh, Massachusetts General Hospital (MGH), Berkeley and the seven-site Multimodal Treatment Study of Children with ADHD (MTA).

Method: All studies were prospective and followed children diagnosed with ADHD and an age and gender-matched control group at regular intervals from childhood (6-12 years) through adolescence into adulthood (20-40 years), evaluating symptom and syndrome persistence, functional outcomes and predictors of these outcomes.

Results: The rates of the ADHD syndrome persistence ranged from 5. Read More

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Genetic sensitivity analysis: Adjusting for genetic confounding in epidemiological associations.

PLoS Genet 2021 Jun 11;17(6):e1009590. Epub 2021 Jun 11.

Department of Health Sciences, University of Leicester, Leicester, United Kingdom.

Associations between exposures and outcomes reported in epidemiological studies are typically unadjusted for genetic confounding. We propose a two-stage approach for estimating the degree to which such observed associations can be explained by genetic confounding. First, we assess attenuation of exposure effects in regressions controlling for increasingly powerful polygenic scores. Read More

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Impact of Parental Impulsivity on Attention Deficit Hyperactivity Disorder and Oppositional Defiant Disorder: Do Mothers' Attitudes Predict Symptom Severity in Children?

J Nerv Ment Dis 2021 Jun 11. Epub 2021 Jun 11.

Department of Child and Adolescent Psychiatry, Balıkesir Atatürk Research and Training Hospital, Balıkesir Department of Child and Adolescent Psychiatry, University of Health Sciences, Dr Sami Ulus Maternity and Children's Research and Training Hospital, Ankara Department of Psychiatry, Balıkesir Atatürk Research and Training Hospital, Balıkesir Department of Child and Adolescent Psychiatry, Aksaray University Research and Training Hospital, Aksaray Department of Child And Adolescent Psychiatry, University of Health Sciences, Ankara Research and Training Hospital Department of Child and Adolescent Psychiatry, University of Health Sciences, Gulhane Training and Research Hospital, Ankara, Turkey.

Abstract: Attention deficit hyperactivity disorder (ADHD) is a chronic neurodevelopmental disorder that occurs early in school-aged children, and it is highly comorbid with oppositional defiant disorder (ODD). Parents of children with ADHD frequently show mental problems related to impulsivity. The aim of this study was to examine the relationship between impulsivity of the mothers and the symptom patterns and severity of children. Read More

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Psychometric properties of a new ADHD screening questionnaire: Parent report on the (potential) underlying explanation of inattention in their school-aged children.

Child Neuropsychol 2021 Jun 11:1-16. Epub 2021 Jun 11.

Department of Neuropsychology & Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, The Netherlands.

The present study examined psychometric properties of a recently developed parent report screening questionnaire, i.e., Parent ADHD Screening questionnaire: Signaling the Core explanation underlying behavioral symptoms (PASSC). Read More

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A neuroimaging dataset on response inhibition and selective attention in adults and children with and without ADHD.

Data Brief 2021 Aug 19;37:107158. Epub 2021 May 19.

Department of Psychology and Human Development, Vanderbilt University, Nashville, TN, USA.

In this article we describe the dataset titled "Response inhibition and selective attention in adults and children with and without ADHD" which is publicly available on OpenNeuro.org. This dataset is comprised of neuroimaging and standardized cognitive assessment scores from 11 adults, 12 children diagnosed with Attention Deficit Hyperactivity Disorder (ADHD) and 15 age matched children without ADHD. Read More

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The Effect of Viloxazine Extended-Release Capsules on Functional Impairments Associated with Attention-Deficit/Hyperactivity Disorder (ADHD) in Children and Adolescents in Four Phase 3 Placebo-Controlled Trials.

Neuropsychiatr Dis Treat 2021 3;17:1751-1762. Epub 2021 Jun 3.

Supernus Pharmaceuticals, Inc., Rockville, MD, USA.

Purpose: The ADHD Rating Scale (ADHD-RS) assesses 18 symptoms of inattention and hyperactivity/impulsivity and has been used in many clinical trials to evaluate the treatment effect of drugs on ADHD. The fifth edition of this scale (ADHD-RS-5) also assesses the impact of inattention and hyperactivity/impulsivity symptoms on six domains of functional impairment (FI): family relationships, peer relationships, completing/returning homework, academic performance at school, controlling behavior at school, and self-esteem. Here, we report the effect of viloxazine extended-release capsules (viloxazine ER), a novel nonstimulant treatment for ADHD in children and adolescents (ages 6-17 years), on FI from a post hoc analysis of four randomized, double-blind, placebo-controlled Phase 3 clinical trials (N=1354). Read More

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Pilot Evaluation of the Medication Integration Protocol for Adolescents with ADHD in Behavioral Care: Treatment Fidelity and Medication Uptake.

J Emot Behav Disord 2016 Dec 30;24(4):223-234. Epub 2015 Oct 30.

The National Center on Addiction and Substance Abuse at Columbia University.

Although Attention-Deficit/Hyperactivity Disorder (ADHD) is prevalent among adolescents in outpatient behavioral care, one of the few evidence-based treatment options, stimulant medication, is significantly underutilized. The Medication Integration Protocol (MIP) is a family-based intervention designed to help behavior therapists assume a lead role in educating clients about ADHD in adolescents, promoting family-centered decisions about medication initiation, and integrating medication management activities within behavioral treatment planning. This pilot study evaluated treatment fidelity and medication utilization for inner-city teens receiving MIP (n = 14) compared to a matched Historical Control (HC) group (n = 21) in a community clinic. Read More

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December 2016

Dietary phytochemical index and attention-deficit/hyperactivity disorder in Iranian children: a case control study.

Eur J Clin Nutr 2021 Jun 10. Epub 2021 Jun 10.

Department of Nutrition, School of Public Health, Shahid Sadughi University of Medical Sciences, Yazd, Iran.

Objective: Attention Deficit/Hyperactivity Disorder (ADHD) is a common behavioral disorder among children. Based on literature, it has been hypothesized that the higher intake of rich sources of phytochemicals may be inversely related to the risk of ADHD. We investigated the association of dietary phytochemical index (DPI) with odds of ADHD. Read More

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Smartphone addiction and associated factors among postgraduate students in an Arabic sample: a cross-sectional study.

BMC Psychiatry 2021 Jun 10;21(1):302. Epub 2021 Jun 10.

Mood Disorders Psychopharmacology Unit, University Health Network, Toronto, ON, Canada.

Background: Smartphone addiction, as with other behavioral addictions, is associated with social, physical, and mental health issues. In this article, we investigated the prevalence of smartphone addiction among postgraduate students and evaluated its correlation with social demographics, depression, attention-deficit/hyperactivity disorder (ADHD), and nicotine dependence.

Objectives: The objective of this study was to investigate the prevalence of smartphone addiction among Middle Eastern postgraduate students, determine the factors associated with smartphone addiction, and estimate the incidence rate of major depressive disorder (MDD), ADHD, insomnia, and nicotine addiction among postgraduate students with smartphone addiction. Read More

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Longitudinal Psychiatric and Developmental Outcomes in 22q11.2 Deletion Syndrome: A Systematic Review.

J Dev Behav Pediatr 2021 Jun-Jul 01;42(5):415-427

Department of Psychology, Syracuse University, Syracuse, NY.

Objective: 22q11.2 deletion syndrome (22q11DS) is a common genetic deletion syndrome associated with psychiatric disorders and developmental delays. A significant amount of 22q11DS research literature is published annually; here, we focus exclusively on longitudinal data that have been published in the past 5 years regarding psychiatric disorders and/or cognitive and social development. Read More

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Parent Attitudes Toward Enhancing Cognition and Clinical Research Trials in Down Syndrome: A Mixed Methods Study.

J Dev Behav Pediatr 2021 Jun-Jul 01;42(5):380-388

Division of Developmental Medicine, Department of Pediatrics, Boston Children's Hospital, Boston, MA.

Objective: As understanding of the neurobiological basis of cognitive impairment in Down syndrome (DS) advances and new pharmaceutical interventions targeting neurodevelopment become available, an in-depth understanding of the family perspective is essential to inform research efforts. A mixed methods study was conducted with parents of individuals with DS to learn about attitudes toward pharmacological interventions to enhance cognition, participation in clinical research trials in DS, and the relationship between child/family-specific factors and parent attitudes.

Method: Parents completed an online survey (N = 37) assessing family/child sociodemographic factors and to capture thoughts on cognitive enhancement and participation in clinical drug trials. Read More

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ADHD should be considered in adolescents with type 1 diabetes and poor metabolic control.

Diabetologia 2021 Jun 9. Epub 2021 Jun 9.

Gillberg Neuropsychiatry Centre, Institute of Neuroscience and Physiology, Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden.

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Deep learning model reveals potential risk genes for ADHD, especially Ephrin receptor gene EPHA5.

Brief Bioinform 2021 Jun 9. Epub 2021 Jun 9.

Peking University Sixth Hospital/Institute of Mental Health, National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital) & the Key Laboratory of Mental Health, Ministry of Health (Peking University), 100191, Beijing, China.

Attention deficit hyperactivity disorder (ADHD) is a common neurodevelopmental disorder. Although genome-wide association studies (GWAS) identify the risk ADHD-associated variants and genes with significant P-values, they may neglect the combined effect of multiple variants with insignificant P-values. Here, we proposed a convolutional neural network (CNN) to classify 1033 individuals diagnosed with ADHD from 950 healthy controls according to their genomic data. Read More

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Genetic and morphological estimates of androgen exposure predict social deficits in multiple neurodevelopmental disorder cohorts.

Mol Autism 2021 Jun 9;12(1):43. Epub 2021 Jun 9.

Department of Psychiatry, University of Iowa, Iowa City, USA.

Background: Neurodevelopmental disorders (NDDs) such as autism spectrum disorder (ASD) display a strong male bias. Androgen exposure is profoundly increased in typical male development, but it also varies within the sexes, and previous work has sought to connect morphological proxies of androgen exposure, including digit ratio and facial morphology, to neurodevelopmental outcomes. The results of these studies have been mixed, and the relationships between androgen exposure and behavior remain unclear. Read More

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Weighted blanket and sleep medication use among adults with psychiatric diagnosis - a population-based register study.

Nord J Psychiatry 2021 Jun 9:1-8. Epub 2021 Jun 9.

Sahlgrenska Academy, University of Gothenburg, Institute of Neuroscience and Physiology, Gothenburg, Sweden.

Objective: To measure rate of subscription of common sleep medication and diagnoses of substance use disorder (SUD) before and after receiving a prescribed weighted blanket (WB) among patients with psychiatric diagnoses.

Materials And Methods: Using register-based data of health-related factors in a Swedish region, a total of 1785 adult individuals with a psychiatric diagnosis, received a WB and resided in the region during the study period were identified. Using each individual as their own control, the rate of one-year prior prescription of WB or diagnosed SUD was compared to rate after a half year wash-out after prescription of WB for a full year. Read More

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Road-Crossing Behavior in Complex Traffic Situations: A Comparison of Children With and Without ADHD.

Child Psychiatry Hum Dev 2021 Jun 9. Epub 2021 Jun 9.

Department of Psychology, Ferdowsi University of Mashhad, Azadi Sq., PO Box: 1518, 9177948974, Mashhad, Iran.

All children are vulnerable to pedestrian injuries, but previous research suggests children diagnosed with ADHD may have elevated risk. Child pedestrian injury risk also increases with increasing traffic volume and speed. The current study examined three hypotheses: (a) Pedestrian behavior of children with ADHD is riskier than that of typically-developing children; (b) Children's pedestrian behavior is riskier with increased traffic complexity; and (c) Pedestrian behavior of children with ADHD is influenced more by complex traffic situations than behavior of typically-developing children. Read More

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Adaptive aspects of impulsivity and interactions with effects of catecholaminergic agents in the 5-choice serial reaction time task: implications for ADHD.

Psychopharmacology (Berl) 2021 Jun 9. Epub 2021 Jun 9.

Department of Psychology and Behavioural and Clinical Neuroscience Institute, University of Cambridge, Downing St., CB2 3EB, Cambridge, UK.

Background: Work in humans has shown that impulsivity can be advantageous in certain settings. However, evidence for so-called functional impulsivity is lacking in experimental animals.

Aims: This study investigated the contexts in which high impulsive (HI) rats show an advantage in performance compared with mid- (MI) and low impulsive (LI) rats. Read More

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Maternal multiple sclerosis is not a risk factor for neurodevelopmental disorders in offspring.

Mult Scler J Exp Transl Clin 2021 Apr-Jun;7(2):20552173211017301. Epub 2021 May 28.

Unit of Child Neuropsychiatry, Department of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy.

Background: Childhood neurodevelopmental disorders (NDDs), including specific learning disorders (SLD), attention deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD), are pathogenically linked to familial autoimmunity and maternal immune-mediated diseases during pregnancy.

Objective: We studied maternal MS as a potential risk factor for NDDs occurrence in offspring.

Methods: MS and control mothers were subjected to questionnaires to ascertain NDD diagnosis in their progeny and the occurrence of both autoimmune and neurodevelopment disorders in their families. Read More

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Changing Academic Support in the Home for Adolescents with Attention-Deficit/Hyperactivity Disorder: A Family-Based Clinical Protocol for Improving School Performance.

Cogn Behav Pract 2016 Feb 25;23(1):14-30. Epub 2014 Jul 25.

Ohio University.

Attention-Deficit/Hyperactivity Disorder (ADHD) is highly prevalent among adolescent clinical populations and associated with myriad deficits in school functioning. Yet, behavior therapists have few developmentally appropriate tools for addressing school problems in this group. This article introduces a behavioral protocol designed to fill the gap: Changing Academic Support in the Home for Adolescents with ADHD (CASH-AA). Read More

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February 2016

Bidirectional and transactional relationships between parenting styles and child symptoms of ADHD, ODD, depression, and anxiety over 6 years.

Dev Psychopathol 2021 Jun 9:1-12. Epub 2021 Jun 9.

Department of Psychology, Stony Brook University, Stony Brook, NY, USA.

It is well established that mothers' parenting impacts children's adjustment. However, much less is known about how children's psychopathology impacts their mothers' parenting and how parenting and child symptoms relate either bidirectionally (i.e. Read More

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Variation in latent social profiles of adolescent ADHD and related clinical features.

Psychiatry Res 2021 May 19;302:114014. Epub 2021 May 19.

School of Psychology, Deakin University, Geelong, VIC, Australia; Murdoch Childrens Research Institute, Parkville, VIC, Australia; Department of Paediatrics, University of Melbourne, Parkville, VIC, Australia. Electronic address:

Social impairment is a hallmark of Attention-deficit/hyperactivity disorder (ADHD), but the extent of variation in adolescent social strengths and weaknesses is unclear. We compared teacher-reported characteristics of social functioning in adolescents with a history of ADHD (N = 340), and without ADHD (N = 182) from the NIMH Collaborative Multisite Multimodal Treatment Study of Children with ADHD (MTA) at 72-month follow-up (13 - 15.9 years-old). Read More

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Evolutionary conservations, changes of circadian rhythms and their effect on circadian disturbances and therapeutic approaches.

Neurosci Biobehav Rev 2021 Jun 5. Epub 2021 Jun 5.

Department of Psychiatry and Psychotherapy, University Medical Center Rostock, Rostock, Gehlsheimer Str. 20, 18147, Rostock, Germany. Electronic address:

The circadian rhythm is essential for the interaction of all living organisms with their environments. Several processes, such as thermoregulation, metabolism, cognition and memory, are regulated by the internal clock. Disturbances in the circadian rhythm have been shown to lead to the development of neuropsychiatric disorders, including attention-deficit hyperactivity disorder (ADHD). Read More

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Effects of substance misuse on inhibitory control in patients with attention-deficit/hyperactivity disorder.

Addict Biol 2021 Jun 7:e13063. Epub 2021 Jun 7.

Department of Psychiatry, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.

Patients with attention-deficit/hyperactivity disorder (ADHD) are often diagnosed with comorbid substance misuse (SM), which is associated with poor treatment efficacy. Although literature indicates similar inhibitory control deficits in both conditions, it is unclear whether SM in ADHD exaggerates pre-existing deficits, with additive or distinct impairments in patients. Our aim was to examine SM effects on inhibitory control in ADHD. Read More

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Gestational exposure to organophosphate pesticides and longitudinally assessed behaviors related to ADHD and executive function.

Am J Epidemiol 2021 Jun 8. Epub 2021 Jun 8.

Center for Environmental Research and Children's Health (CERCH), School of Public Health, University of California at Berkeley, Berkeley, California, United States.

The prefrontal cortex directs higher-order cognitive and behavioral processes important for attention, working memory, and inhibitory control. We investigated whether gestational exposure to organophosphate (OP) pesticides was associated with these abilities in childhood and early adolescence. We enrolled pregnant women between 1999-2000 in a birth cohort drawn from an agricultural region of California. Read More

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A retrospective observational cohort study: Epidemiology and outcomes of pediatric unintentional falls in US emergency departments.

Injury 2021 May 16. Epub 2021 May 16.

Emergency Medicine, Stanford University School of Medicine, Stanford, CA, United States. Electronic address:

Introduction: The objective is to determine how outcomes from unintentional falls differ for children with and without developmental disabilities, with a sensitivity analysis specifically examining those with ADHD.

Materials And Methods: This is a retrospective observational cohort study of 2010-2015 data from the Nationwide Emergency Department Sample (NEDS). The NEDS is a sampling of ED visits across 953 hospitals in 36 states. Read More

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Neuroendoscopic treatment of symptomatic cyst of the septum pellucidum in children: A case series.

Clin Neurol Neurosurg 2021 May 8;207:106671. Epub 2021 May 8.

Pediatric Neurosurgery Santobono-Pausilipon Children's Hospital, Naples, Italy.

Background: Symptomatic cysts of the septum pellucidum (CSP) are extremely rare in children and surgical indications are not well defined. A very careful clinical and neuroradiologic evaluation is necessary to consider a patient for surgical indication.

Methods: We present a surgical series of 7 pediatric patients. Read More

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Do referral factors predict a probable Autism Spectrum Disorder diagnosis? A DBPNet Study.

Acad Pediatr 2021 Jun 4. Epub 2021 Jun 4.

Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.

Objective: To determine the proportion of children referred to academic medical centers with concerns about Autism Spectrum Disorders (ASD) who received a probable ASD diagnosis, identify factors predicting ASD diagnosis and describe the children with ASD concerns who were not found to have autism.

Methods: 55 Developmental-Behavioral Pediatricians (DBP) at 12 academic sites in the DBPNet research network recorded data on ≤15 consecutive new patients. They coded presumed diagnoses after their first visit with the child. Read More

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Attention-Deficit/Hyperactivity Disorder Symptoms and Externalizing Progression in the LAMS Study: A Test of Trait Impulsivity Theory.

J Am Acad Child Adolesc Psychiatry 2021 Jun 2. Epub 2021 Jun 2.

The Ohio State University, Columbus; Nisonger Center for Excellence in Disabilities. Morgantown, West Virginia. Electronic address:

Objective: Test differential prospective prediction of growth in externalizing behavior, including oppositional defiant disorder (ODD), conduct disorder (CD) and substance use disorders (SUDs), by earlier hyperactive-impulsive (HI) versus inattentive (IN) symptoms of attention-deficit/hyperactivity disorder (ADHD).

Method: Participants in the Longitudinal Assessment of Manic Symptoms (LAMS) Study (N=685 at study entry), including 458 boys and 227 girls ages 6-12, completed full parent- and self-report assessments every year for eight years on the Kiddie Schedule for Affective Disorders and Schizophrenia. Three sets of analyses were conducted. Read More

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