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Molecular insight into the genomic variation of SARS-CoV-2 strains from current outbreak.

Comput Biol Chem 2021 Jun 18;93:107533. Epub 2021 Jun 18.

Department of Mathematics, Jashore University of Science and Technology, Jashore, 7408, Bangladesh. Electronic address:

Coronavirus disease 2019 (COVID-19) is the newly emerging viral disease, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The epidemic sparked in December 2019 at Wuhan city, China that causes a large global outbreak and a major public health catastrophe. Till now, more than 129 million positive cases have been reported in which more than 2. Read More

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Evaluation of online, publicly available cancer-related educational and self-management resources for symptom management.

Psychooncology 2021 Jun 24. Epub 2021 Jun 24.

Schulich Library of Physical Sciences, Life Sciences, and Engineering, McGill University, 845 Sherbrooke West, Montreal, QC, H3A 0G4, Canada.

Objective: The aims of this study were to evaluate the readability, suitability, and quality of publicly available online self-management (SM) resources for people with cancer.

Methods: Resources were identified using two strategies: a) a targeted search of 20 Canadian organizations and b) a Google search. These were evaluated using the Suitability Assessment of Materials (SAM), the DISCERN tool for quality, and readability indices. Read More

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Radiotherapy of brain metastasis from lung cancer in limited resource settings.

J Thorac Dis 2021 May;13(5):3308-3314

Department of Radiation Oncology, Tata Memorial centre, Homi Bhabha National Institute, Mumbai, India.

Radiotherapy is one of the most commonly used treatment modality for brain metastases from lung cancer. Its use has evolved from conventional whole brain radiation therapy (WBRT) to more sophisticated stereotactic radiosurgery (SRS) and hippocampal sparing radiotherapy. Indications of cranial radiotherapy are also evolving with the advent of targeted therapies directed against molecular markers like epidermal growth factor receptor (EGFR) and anaplastic lymphoma kinase (ALK). Read More

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Attitudes, Knowledge, and Skills Toward Adopting Evidence-Based Practice in Clinical Decision-Making of Registered Nurses in Saudi Arabia.

Alia Almoajel

Res Theory Nurs Pract 2021 Jun 23. Epub 2021 Jun 23.

College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia

Background And Purpose: Evidence-based practice (EBP) is generally recognized as a fundamental tenet of cost-effective and high-quality patient care. Nurses must be engaged with the appropriate attitude and educated with essential competencies to implement EBP systematically into their daily practice. This study assessed the attitudes, knowledge, and skills of registered nurses toward the adoption of EBP in making clinical decisions in their practice. Read More

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Overuse of antenatal visits and ultrasounds in low-risk women: A national population-based study.

Paediatr Perinat Epidemiol 2021 Jun 23. Epub 2021 Jun 23.

Université de Paris/ Center of Research in Epidemiology and StatisticS(CRESS)/ Obstetrical Perinatal and Pediatric Epidemiology Research Team (EPOPé)/ INSERM/ INRA, Paris, France.

Background: A better understanding of the overuse of antenatal care is needed to improve its organisation to deal with limited medical resources and doctor shortages.

Objectives: To assess the proportion of women who overuse antenatal care and the associations of overuse with maternal characteristics and the qualifications of healthcare providers.

Methods: We used the 2016 National Perinatal Survey, a cross-sectional population-based survey, performed in all maternity units in France, including 13,132 women. Read More

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Knowledge and attitudes towards baby-led-weaning by health professionals and parents: A cross-sectional study.

Enferm Clin 2021 Jun 19. Epub 2021 Jun 19.

Escuela Universitaria de Enfermería Dr. Dacio Crespo, Universidad de Valladolid, Av. San Telmo, s/n, 34004 Palencia, Spain; Facultad de Ciencias de la Salud, Universidad Isabel I de Castilla, C/ Fernán González, 76, 09003 Burgos, Spain.

Objective: Baby-led-weaning (BLW) is a novel model of complementary feeding. Although there is little scientific evidence to support the suitability or superiority of this complementary feeding model, BLW is followed by many families today. The aim was to evaluate the knowledge and attitudes of a group of parents and health professionals regarding BLW in Spain. Read More

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Who should be tested in a pandemic? Ethical considerations.

BMC Med Ethics 2021 Jun 22;22(1):76. Epub 2021 Jun 22.

Department of Learning, Informatics, Management and Ethics, Karolinska Institutet, 171 77, Stockholm, Sweden.

Background: In the initial phase of the Covid-19 pandemic, difficult decisions had to be made on the allocation of testing resources. Similar situations can arise in future pandemics. Therefore, careful consideration of who should be tested is an important part of pandemic preparedness. Read More

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Home is where the safer ground is: the need to promote affordable housing laws and policies in receiving communities.

J Environ Stud Sci 2021 Jun 16:1-14. Epub 2021 Jun 16.

Georgetown Climate Center, Georgetown University Law Center, 600 New Jersey Avenue NW, Washington, DC 20001 USA.

Increasingly frequent and intense extreme weather events are pushing communities to confront difficult decisions in order to protect people and infrastructure sitting in harm's way. One decision is around managed retreat or the voluntary movement and transition of individuals and communities away from coastal and other climate-vulnerable areas. "Receiving communities" and other low-risk areas where people may choose to relocate must adopt a multi-pronged strategy that addresses the full breadth of services and resources that relocating residents will need in order to adapt to their new communities, such as in areas of health, education, and workforce development. Read More

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Fertigation with fish farming effluent at the adequate phenological stages improves physiological responses, production and quality of cherry tomato fruit.

Int J Phytoremediation 2021 Jun 21:1-10. Epub 2021 Jun 21.

Department of Agricultural Sciences, Federal Rural University of the Semi-Arid (UFERSA), Mossoró, Brazil.

The use of effluent from fish farming in the greenhouse increases the availability of water and reduces the risk of environmental contamination due to improper disposal. Therefore, a study in a greenhouse was carried out to evaluate the effects of fertigation utilizing fish farming effluent at different phenological stages of cherry tomato. Plants of cherry tomato were fertigated with fish farming effluent (E) alternated with tap water (W) at the four phenological stages of the crop (growth, flowering, fruit formation and ripening). Read More

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A social-cultural analysis of the individual education plan practice in special education schools in China.

Int J Dev Disabil 2018 Oct 13;66(1):54-66. Epub 2018 Oct 13.

University of California Santa Barbara, Santa Barbara, CA, USA.

The objective of this study was to gain insight into how Chinese special education teachers conceptualize individual education plan (IEP) and how IEP is implemented in their daily work. Fourteen administrators and teachers from several special education schools in three metropolitan cities in China were interviews about their perspective of IEP and IEP practice at their work. The results suggested that despite remaining concerns about the implementation of IEP Chinese teachers highly commit to the value of IEP. Read More

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October 2018

A comparative study of public health and social measures of COVID-19 advocated in different countries.

Di Wang Zhifei Mao

Health Policy 2021 Jun 5. Epub 2021 Jun 5.

School of Media and Communication, Shenzhen University, Shenzhen 518052, China. Electronic address:

Coronavirus 2019 (COVID-19) has had a significant impact on the world. Different countries introduced various public health and social measures (PHSMs) against the coronavirus. This paper aims to (a) examine how national policies on PHSMs were framed and which PHSMs were adopted; (b) compare the similarities and differences of PHSMs advocated by different countries; and (c) examine whether these measures have changed with time. Read More

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Health Care Providers' Perceived Barriers to Screening for Substance Use During Pregnancy.

Nurs Womens Health 2021 Jun 16. Epub 2021 Jun 16.

Objective: To explore health care providers' perceived barriers to conducting standardized screening processes for substance use during pregnancy.

Design: Descriptive survey.

Setting/local Problem: A health system in the northwestern United States where there was a lack of consistent substance use screening in prenatal clinics. Read More

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Discontinuation of Continuation or Maintenance Electroconvulsive Therapy Caused by the COVID-19 Pandemic: A Naturalistic Study Investigating Relapse in Patients With Major Depressive Disorder.

J ECT 2021 Jun 17. Epub 2021 Jun 17.

From the Department of Psychiatry, Ghent University Hospital, Ghent Department of Psychiatry, AZ Groeninge, Kortrijk Department of Head and Skin-Psychiatry and Medical Psychology, Ghent University, Ghent, Belgium.

Background: Continuation or maintenance electroconvulsive therapy (C/M-ECT) is recommended to reduce relapse rates of patients with major depressive disorder. During the ongoing COVID-19 pandemic, ECT services have come under pressure or needed to close because of redirected resources and safety reasons. We investigated the impact of C/M-ECT discontinuation on relapse in patients with unipolar depressive disorder in Flanders, Belgium. Read More

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Nitrogen fertilizer application rate impacts eating and cooking quality of rice after storage.

PLoS One 2021 18;16(6):e0253189. Epub 2021 Jun 18.

Institute of Plant Nutrition and Environmental Resources, Liaoning Academay of Agricultural Sciences, Shenyang, People's Republic of China.

The effect of nitrogen fertilizer application on the quality of rice post-storage is not well understood. The eating and cooking quality (ECQ) of rice treated with 0 (CK, control), 160 (IN, insufficient nitrogen), 260 (AN, adequate nitrogen), and 420 (EN, excessive nitrogen) kg N/ha was analyzed over 12 months of storage. Results showed that the rate of nitrogen fertilizer application had no significant impact on the changes in taste value during storage. Read More

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An Initial Preparation for Human Cadaveric Dissection Ameliorates the Associated Mental Distress in Students.

Anat Sci Educ 2021 Jun 18. Epub 2021 Jun 18.

School of Occupational Therapy, College of Health Sciences, Husson University, Bangor.

It is universally recognized that cadaveric dissection is an essential part of anatomy training. However, it has been reported to induce mental distress in some students and impair their intrinsic motivation to study. One of the postulated reasons for this behavior is the lack of adequate information and preparation of students for cadaveric dissection. Read More

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Canadian Airway Focus Group updated consensus-based recommendations for management of the difficult airway: part 1. Difficult airway management encountered in an unconscious patient.

Can J Anaesth 2021 Jun 18. Epub 2021 Jun 18.

Department of Emergency Medicine, QEII Health Sciences Centre, Dalhousie University, 1796 Summer Street, Halifax, NS, B3H 3A7, Canada.

Purpose: Since the last Canadian Airway Focus Group (CAFG) guidelines were published in 2013, the literature on airway management has expanded substantially. The CAFG therefore re-convened to examine this literature and update practice recommendations. This first of two articles addresses difficulty encountered with airway management in an unconscious patient. Read More

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The Veterinary Treatment Facility as a Readiness Platform for Veterinary Corps Officers.

Mil Med 2021 Jun 18. Epub 2021 Jun 18.

Veterinary Services and Public Health Sanitation Directorate, U.S. Army Public Health Center, Aberdeen Proving Ground, MD 21010, USA.

Introduction: U.S. Army Veterinary Corps provides highly skilled and adaptive veterinary professionals to protect and improve the health of people and animals while enhancing readiness throughout the DOD. Read More

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Ten physiological commandments for severe head injury.

Rev Esp Anestesiol Reanim (Engl Ed) 2021 May 15;68(5):280-292. Epub 2021 May 15.

Departamento de Medicina, Universidad de Sevilla, Sevilla, Spain.

Advances in multiparametric brain monitoring have allowed us to deepen our knowledge of the physiopathology of head injury and how it can be treated using the therapies available today. It is essential to understand and interpret a series of basic physiological and physiopathological principles that, on the one hand, provide an adequate metabolic environment to prevent worsening of the primary brain injury and favour its recovery, and on the other hand, allow therapeutic resources to be individually adapted to the specific needs of the patient. Based on these notions, this article presents a decalogue of the physiological objectives to be achieved in brain injury, together with a series of diagnostic and therapeutic recommendations for achieving these goals. Read More

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Rapid realist review of the role of community pharmacy in the public health response to COVID-19.

BMJ Open 2021 06 16;11(6):e050043. Epub 2021 Jun 16.

Primary Care Health Sciences, University of Oxford, Oxford, UK.

Introduction: Community pharmacists and their teams have remained accessible to the public providing essential services despite immense pressures during the COVID-19 pandemic. They have successfully expanded the influenza vaccination programme and are now supporting the delivery of the COVID-19 vaccination roll-out.

Aim: This rapid realist review aims to understand how community pharmacy can most effectively deliver essential and advanced services, with a focus on vaccination, during the pandemic and in the future. Read More

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[Assessment of the municipal administration in the promotion of rational use of medicines in medium and large cities in Santa Catarina, Brazil].

Cad Saude Publica 2021 9;37(5):e00112920. Epub 2021 Jun 9.

Universidade Federal de Santa Catarina, Florianópolis, Brasil.

This article aimed to assess the municipal administration in the promotion of rational use of medicines in cities with 100,000 inhabitants or more in the State of Santa Catarina, Brazil. The study began with the adaptation of an assessment model consisting of 28 indicators, analyzing the development of activities in promotion of rational use of medicines through the educational, structural, administrative, and operational dimensions of pharmaceutical care. Data collection used an online questionnaire, tested and validated, through a virtual platform, sending a link to the respondent's e-mail address. Read More

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Strengthening Pathology Capacity to Deliver Quality Cancer Care in Cities in LMICs.

JCO Glob Oncol 2021 Jun;7:917-924

American Society for Clinical Pathology, Chicago, IL.

Diagnostic pathology services for oncology health systems are essential; yet, surveys, observations, and hard data from across low- and middle-income countries have revealed that these services are almost always lacking adequate quality and often missing completely. The City Cancer Challenge Foundation (C/Can), the American Society for Clinical Pathology, and C/Can partner cities undertook intense analysis of their existing pathology services as part of a year-long assessment process including the specific formation of a pathology-focused team. Internal and external expert assessments identified sustainable solutions adapted to the local context and level of resources and created specific local implementation projects. Read More

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Updating recommendations of the Brazilian Group of Flow Cytometry (GBCFLUX) for diagnosis of acute leukemias using four-color flow cytometry panels.

Hematol Transfus Cell Ther 2021 May 21. Epub 2021 May 21.

Hospital Amaral Carvalho, Jaú, SP, Brazil.

Introduction: Flow cytometry has become an increasingly important tool in the clinical laboratory for the diagnosis and monitoring of many hematopoietic neoplasms. This method is ideal for immunophenotypic identification of cellular subpopulations in complex samples, such as bone marrow and peripheral blood. In general, 4-color panels appear to be adequate, depending on the assay. Read More

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Rational use of PPE and preventing PPE related skin damage.

J Family Med Prim Care 2021 Apr 29;10(4):1547-1553. Epub 2021 Apr 29.

COVID-19 Committee Members: Director and CEO, All India Institute of Medical Sciences (AIIMS), Basni, Jodhpur, Rajasthan, India.

On 31 December, 2019, an outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was declared in Wuhan, China. On 24 March 2020, there was a nationwide lockdown for 21 days, followed by Janata curfew on 22 March. As the pandemic has developed and spread across continents, everyone including policy makers have realized shortage of personal protective equipment (PPE) such as N95 respirators, coverall, and face shields. Read More

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Physicians' Opinions of COVID-19 Ambulatory Care Constraints: A Survey of Sickle Cell Clinicians.

J Ambul Care Manage 2021 Jun 11. Epub 2021 Jun 11.

Division of Pediatric Anesthesiology, Department of Anesthesiology, The University of North Carolina at Chapel Hill School of Medicine, Chapel Hill (Dr Kenney); Center for Health Equity, Department of Information and Decision Sciences, California State University, San Bernardino (Dr Becerra); Blood Research Center, The University of North Carolina at Chapel Hill School of Medicine, Chapel Hill (Mr Beatty); and Division of General Internal Medicine, Department of Internal Medicine, Virginia Commonwealth University School of Medicine, Richmond (Dr Smith).

Ambulatory specialty care operations have been challenged by the coronavirus disease-2019 (COVID-19) pandemic. We surveyed sickle cell disease (SCD) specialists to assess the effect of pandemic-associated factors on SCD center ambulatory equipment, operations, personnel, and finances. Thirty-two participants from 27 SCD centers completed our survey. Read More

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Predictors of Burden and Resilience in Family Caregivers of Individuals With Opioid Use Disorder.

J Addict Nurs 2021 Jun 11. Epub 2021 Jun 11.

Mirinda Brown Tyo, PhD, RN, TCRN, Mary K. McCurry, PhD, RNC, ANP, ACNP, June Andrews Horowitz, PhD, RN, PMHCNS-BC, FAAN, and Kathleen Elliott, DNP, ANP-BC, University of Massachusetts Dartmouth.

Background: Family caregivers are an essential resource for individuals with opioid use disorder (OUD). Overburdened caregivers often experience detrimental effects to their emotional and physical well-being.

Method: A cross-sectional, nonexperimental, correlational study was used to identify correlates and predictors of burden and resilience in caregivers of care recipients with OUD. Read More

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Beyond financial proxies in Cohesion Policy inputs' monitoring: A system dynamics approach.

Eval Program Plann 2021 May 31;89:101964. Epub 2021 May 31.

Department of Computer Science and Engineering (DISI), School of Science, Alma Mater Studiorum - University of Bologna, Mura Anteo Zamboni 7, Bologna, 40126, Italy.

European Union's Cohesion Policy aims to foster development and reduce disparities among regions by redistributing more than one-third of the European budget. Given the policy's importance and complexity, an elaborated monitoring and evaluation system has been established. While attention has been dedicated to evaluating policy impact, the monitoring of inputs (i. Read More

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Framework for Solid-Organ Transplantation During COVID-19 Pandemic in Europe.

Risk Manag Healthc Policy 2021 4;14:2421-2433. Epub 2021 Jun 4.

General, Visceral, and Transplant Surgery, Department of Surgery, Medical University of Graz, Graz, Austria.

Introduction: Since the effect of the COVID-19 pandemic on solid-organ transplantation (SOT) is unclear, an online survey on the specific framework of leading European transplant centers (n=155) in 31 European countries was conducted between April 24 and May 15, 2020.

Methods: A questionnaire was designed to collect information on restrictions on SOT, protective measures,(non)governmental information policies, and individual opinions on how to deal with SOT during COVID-19.

Results: The response rate was 37. Read More

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A massive rock and ice avalanche caused the 2021 disaster at Chamoli, Indian Himalaya.

Science 2021 Jun 10. Epub 2021 Jun 10.

Department of Geography, University of Utah; Salt Lake City, Utah, USA.

On 7 Feb 2021, a catastrophic mass flow descended the Ronti Gad, Rishiganga, and Dhauliganga valleys in Chamoli, Uttarakhand, India, causing widespread devastation and severely damaging two hydropower projects. Over 200 people were killed or are missing. Our analysis of satellite imagery, seismic records, numerical model results, and eyewitness videos reveals that ~27x10 m of rock and glacier ice collapsed from the steep north face of Ronti Peak. Read More

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[Virtual consultations in Traumatology and Orthopaedic Surgery].

Semergen 2021 Jun 7. Epub 2021 Jun 7.

Unidad de Investigación, Hospital Universitario de Nuestra Señora de Candelaria, Santa Cruz de Tenerife, España.

Objective: The objective of this study is to analyse the current system of virtual consultations between the levels of Primary and Specialised Care in the field of Traumatology and Orthopaedic Surgery (TOS) in our healthcare area.

Material And Method: A retrospective observational study was carried out on 90 consecutive patients who had a non-face-to-face consultation between 3 January 2017 and 10 February 2017 and subsequently a face-to-face consultation. All the patients belonged to the same healthcare area attached to the Nuestra Señora de Candelaria University Hospital. Read More

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Development and implementation of a perioperative management guide for patients with hip fracture: Health management and clinical impact.

Rev Esp Cir Ortop Traumatol 2021 Jul-Aug;65(4):294-304

Facultativo especialista de Área de Anestesiología y Reanimación, Hospital Universitario Puerta de Hierro, Majadahonda Madrid, Spain.

Introduction: Hip fracture (HF) in the elderly has a high prevalence and risk of morbidity and mortality in the short and long term. It can reduce life expectancy by almost 2 years, and require permanent socio-sanitary assistance in one in 5 patients. Its management as a process where the patient takes priority over the activities of the organisation can bring new perspectives, optimisation tools and redesign of the workflow to make it more efficient. Read More

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