2,289 results match your criteria adenotonsillectomy children


Nasal Sprays Containing Mometasone Furoate for Relief of Post-Adenotonsillectomy Pain in Children: A Prospective Controlled Study.

Sisli Etfal Hastan Tip Bul 2021 17;55(1):101-107. Epub 2021 Mar 17.

Department of Otorhinolaryngology Head and Neck Surgery, University of Health Sciences Turkey, Sisli Hamidiye Etfal Teaching and Research Hospital, Istanbul, Turkey.

Objectives: Adenotonsillectomy is one of most common surgeries performed in childhood. Post-operative pain associated particularly with tonsillectomy is still a problem for many physicians. Despite advances in surgical techniques, analgesics, or anti-inflammatory drugs, no unique strategy for post-tonsillectomy pain management has been suggested. Read More

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Obstructive sleep apnea and fractures in children and adolescents.

J Clin Sleep Med 2021 Apr 30. Epub 2021 Apr 30.

Department of Nutritional Sciences, School of Public Health, University of Michigan, Ann Arbor, MI.

Study Objectives: To examine, among girls and boys, associations between site-specific extremity fracture and sleep apnea diagnosis or treatment.

Methods: A cross-sectional analysis of claims data from 2016-2018 for children aged 2-18. Children with sleep apnea, continuous positive airway pressure, adenotonsillectomy, and fracture were identified using ICD10, CPT and HCPCS codes. Read More

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Orofacial Myofunctional Therapy in Obstructive Sleep Apnea Syndrome: A Pathophysiological Perspective.

Medicina (Kaunas) 2021 Apr 1;57(4). Epub 2021 Apr 1.

Clinic of Pneumology and Allergology, Center for Sleep Medicine and Respiratory Care, Institute for Pneumology at the University Witten/Herdecke, 42699 Solingen, Germany.

Obstructive sleep apnea (OSA) syndrome is a multi-factorial disorder. Recently identified pathophysiological contributing factors include airway collapsibility, poor pharyngeal muscle responsiveness, a low arousal threshold, and a high loop gain. Understanding the pathophysiology is of pivotal importance to select the most effective treatment option. Read More

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Sleep-disordered breathing and its management in children with rare skeletal dysplasias.

Am J Med Genet A 2021 Apr 28. Epub 2021 Apr 28.

AP-HP, Hôpital Necker-Enfants Malades, Pediatric Noninvasive Ventilation and Sleep Unit, Paris, France.

Sleep-disordered breathing (SDB) is common in patients with skeletal dysplasias. The aim of our study was to analyze SDB and respiratory management in children with rare skeletal dysplasias. We performed a retrospective analysis of patients with spondyloepiphyseal dysplasia congenita (SEDC), metatropic dysplasia (MD), spondyloepimetaphyseal dysplasia (SEMD), acrodysostosis (ADO), geleophysic dysplasia (GD), acromicric dysplasia (AD), and spondylocostal dysplasia (SCD) between April 2014 and October 2020. Read More

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Evaluation of the role of microlaryngotracheobronchoscopy (MLTB) with adenotonsillectomy in 158 children with sleep disordered breathing.

Clin Otolaryngol 2021 Apr 25. Epub 2021 Apr 25.

Department of ENT, Sheffield Children's Hospital, UK.

Recent studies of adenotonsillectomies have reported failure rates of up to 40% in the treatment of OSA. Previous studies have suggested multi-level airway obstruction as a possible cause of residual OSA. Exercise intolerance and discordance between tonsil size and symptoms may help predict airway pathology. Read More

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Perfusion index as an objective measure of postoperative pain in children undergoing adenotonsillectomy: a cohort study.

J Clin Monit Comput 2021 Apr 23. Epub 2021 Apr 23.

Department of Anesthesiology, Surgical ICU and Pain Management, Kasr Alainy Faculty of Medicine, Cairo University- Egypt, 1-Al saraya st, Almanial, Cairo, Egypt.

Postoperative pain in children is usually undertreated because of their inability to complain. While several pain assessment scales have been developed, they have shortcomings such as subjectivity and being observer-dependent. This study aimed to assess the validity of the perfusion index as an objective measure of postoperative pain in children undergoing adenotonsillectomy. Read More

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Comparative Evaluation of the Effects of Adenotonsillar Hypertrophy on Oral Health in Children.

Biomed Res Int 2021 2;2021:5550267. Epub 2021 Apr 2.

Department of Pediatric Dentistry, Near East University Faculty of Dentistry, Nicosia/ TRNC, 99138 Mersin 10, Turkey.

We aimed to investigate the oral health of children in terms of the presence of dental caries, periodontal health, halitosis, and dentofacial changes in patients who had adenotonsillar hypertrophy related to mouth breathing and compared these findings with nasal breathing healthy and adenotonsillectomy-operated children. The patient group comprised 40 mouth-breathing children who were diagnosed with adenotonsillar hypertrophy, while the control group consisted of 40 nasal breathing children who had no adenotonsillar hypertrophy. Forty children who had undergone an adenotonsillectomy operation at least 1 year prior to the study were included in the treatment group. Read More

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Improvement in BMI z-score following adenotonsillectomy in adolescents aged 12-18 years: a retrospective cohort study.

BMC Pediatr 2021 Apr 20;21(1):184. Epub 2021 Apr 20.

Department of Pediatrics, Carmel Hospital and Technion Faculty of Medicine, Haifa, Israel.

Background: Characteristics of obstructive sleep apnea (OSA) changes with age. Infants, toddlers and prepubertal children with OSA are usually underweight and may suffer from failure to thrive (FTT). Adenotonsillectomy (T&A) is the first line of treatment for OSA in childhood. Read More

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Eosinophils Are More Strongly Relevant to Allergic Sensitization Than Basophils in Pediatric Adenotonsillar Hypertrophy.

Front Pediatr 2021 31;9:598063. Epub 2021 Mar 31.

Department of Otorhinolaryngology, Qilu Hospital of Shandong University, NHC Key Laboratory of Otorhinolaryngology (Shandong University), Jinan, China.

The relationship between eosinophils/basophils and allergic sensitization is not clear in pediatric adenotonsillar hypertrophy (ATH). The objective of this study is to investigate the relationship between eosinophil/basophil counts and peripheral specific IgE levels, and identify the common allergens in children with ATH. We initially screened 1,031 consecutive children who underwent adenotonsillectomy in our department from June 2018 to June 2019, and finally included 676 children. Read More

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The comparison of ketamine with tramadol for postoperative pain relief on children following adenotonsillectomy or tonsillectomy: A meta-analysis of randomized controlled trials.

Medicine (Baltimore) 2021 Apr;100(14):e22541

Department of Pediatrics, The First People's Hospital of Xiaoshan, Hangzhou, Zhejiang Province, P.R. China.

Introduction: The comparison of ketamine with tramadol for pain control remains controversial in pediatric adenotonsillectomy or tonsillectomy. We conduct a systematic review and meta-analysis to explore the efficacy of ketamine vs tramadol for pain relief in children following adenotonsillectomy or tonsillectomy.

Methods: We have searched PubMed, EMbase, Web of science, EBSCO, and Cochrane library databases through October 2019 for randomized controlled trials (RCTs) assessing the effect of ketamine vs tramadol for pediatric adenotonsillectomy or tonsillectomy. Read More

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Quality-of-life but not behavior improves 48-months post-adenotonsillectomy in children with SDB.

Sleep Med 2021 May 11;81:418-429. Epub 2021 Mar 11.

University of Adelaide, Adelaide, Australia.

Background: Long term follow-up studies (>12 mths) of changes in behavior and quality-of-life (QoL) in children with sleep disordered breathing (SDB) post-adenotonsillectomy are limited and there is a lack of consensus in the reported findings. The aim of this study was to evaluate children's sleep, QoL and behavior at baseline and 6 mths and 48 mths post-adenotonsillectomy for clinically diagnosed SDB.

Methods: This prospective longitudinal study of children aged 3-12 y recruited from a Children's Hospital otolaryngology clinic compared polysomnographic parameters, behavior (Child Behavior Checklist; CBCL) and QoL (OSA-18) at baseline, 6mths and 48mths post-adenotonsillectomy and compared these parameters to healthy non-snoring controls recruited from the general community at the same time points. Read More

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Paediatrics: how to manage obstructive sleep apnoea syndrome.

Drugs Context 2021 26;10. Epub 2021 Mar 26.

Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada.

Obstructive sleep apnoea syndrome (OSAS) is defined as the intermittent reduction or cessation of airflow due to partial or complete obstruction of the upper airway during sleep. Paediatric OSAS has specific contributing factors, presenting symptoms and management strategies in various age groups. Untreated OSAS can lead to detrimental effects on neurocognitive development and cardiovascular and metabolic functions of a growing child. Read More

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Effect of surgical intervention for mild childhood obstructive sleep apnoea on attention and behavioural outcomes: A randomized controlled study.

Respirology 2021 Apr 1. Epub 2021 Apr 1.

Department of Paediatrics, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong.

Background And Objective: We evaluated inattention and behavioural outcomes following surgery versus watchful waiting (WW) in school-aged children with mild obstructive sleep apnoea (OSA).

Methods: A prospective randomized controlled study was performed in pre-pubertal children aged 6-11 years with polysomnography (PSG)-confirmed mild OSA. They were assigned randomly to early surgical intervention (ES) or WW. Read More

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Impact of a revised postoperative care plan on pain and recovery trajectory following pediatric tonsillectomy.

Paediatr Anaesth 2021 Mar 31. Epub 2021 Mar 31.

Department of Anaesthesia and Pain Medicine, Perth Children's Hospital, Perth, WA, Australia.

Background: A previous cohort of adenotonsillectomy patients at our institution demonstrated moderate-severe post-tonsillectomy pain scores lasting a median (range) duration of 6 (0-23) days and postdischarge nausea and vomiting affecting 8% of children on day 1 following surgery. In this subsequent cohort, we evaluate the impact of changes to our discharge medication and parental education on post-tonsillectomy pain and recovery profile.

Methods: In this follow-on, prospective observational cohort study, all patients undergoing tonsillectomy at our institution during the study period were discharged with standardized analgesia. Read More

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Adenotonsillectomy Does not Alter the Risk of Upper Airway Infections in Children.

Laryngoscope 2021 Mar 15. Epub 2021 Mar 15.

Department of Otorhinolaryngology-Head and Neck Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.

Objective: Given the conflicting evidence regarding adenotonsillectomy and the risk of upper airway infections (UAIs), including acute pharyngitis (APT), rhinosinusitis (ARS), and otitis media (AOM), we evaluated the risk of developing UAIs following adenotonsillectomy in a childhood population.

Methods: In this population-based follow-up study, we used data from the National Health Insurance Service-National Sample Cohort. The adenotonsillectomy group (n = 2,377) included patients aged <10 years who underwent an adenotonsillectomy. Read More

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Letter to Editor on "Changes in Acoustic Aspects of Voice Function in Children After Adenotonsillectomy".

J Voice 2021 Mar 9. Epub 2021 Mar 9.

Professor, Department of ENT, Christian Medical College, Vellore, Tamil Nadu, India.

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Intraoperative clonidine to prevent postoperative emergence delirium following sevoflurane anesthesia in pediatric patients: a randomized clinical trial.

Braz J Anesthesiol 2021 Jan-Feb;71(1):5-10. Epub 2020 Dec 25.

Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Departamento de Anestesiologia, Recife, PE, Brazil. Electronic address:

Introduction And Objective: Emergence Delirium (ED), particularly in children, is characterized by mental confusion, irritability, disorientation, and inconsolable crying. ED prolongs the time required in the Post-Anesthesia Care Unit (PACU) and increases concern and anxiety in parents. The present study aimed to determine the effectiveness and safety of low-dose clonidine in preventing ED in children receiving sevoflurane anesthesia for tonsillectomy/adenotonsillectomy. Read More

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December 2020

The role of antibiotics in the surgical management of paediatric obstructive sleep apnoea (OSA): a cohort study.

Eur Arch Otorhinolaryngol 2021 Mar 9. Epub 2021 Mar 9.

Department of Paediatric and Adult ENT Surgery, The Royal London Hospital, Whitechapel Road, London, E1 1BB, UK.

Purpose: Obstructive sleep apnoea (OSA) describes an irregular night-time breathing pattern that is present in approximately 1.8% of children and can have a negative impact on quality of life. The use of antibiotics postoperatively is controversial. Read More

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Incidence of allergen-specific and total immunoglobulin E positivity in children undergoing adenotonsillectomy.

J Paediatr Child Health 2021 Mar 8. Epub 2021 Mar 8.

Illawarra Shoalhaven Local Health District, The Wollongong Hospital, Wollongong, New South Wales, Australia.

Aim: To conduct a prospective, consecutive cohort study to evaluate the incidence of allergen-specific and total immunoglobulin E (IgE) in a paediatric population undergoing adenotonsillectomy for sleep-disordered breathing.

Methods: A total of 64 consecutive patients presenting for adenotonsillectomy at a single centre were recruited over a period of 3 months. All patients underwent adenotonsillectomy and had allergen-specific and total IgE serum testing at the time of anaesthesia induction. Read More

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Mothers level of education and preoperative informative story book reading helps reduce preoperative anxiety in children in Turkey.

J Pediatr Nurs 2021 Feb 20. Epub 2021 Feb 20.

University of Health Sciences, Dışkapı Yıldırım, Beyazıt Training and Education Hospital, Anesthesiology and Reanimation Clinic, Şehit Ömer Halisdemir caddesi no:12 Dışkapı, Ankara, Turkey.

Purpose: This study aimed to evaluate the use of a standard story book, compared to an informative story book, as preoperative preparation to relieve anxiety.

Design And Methods: A total of 120 children with ASA I-II, aged 6-8 years, scheduled to undergo elective adenoidectomy, tonsillectomy, and adenotonsillectomy were enrolled in this randomized controlled study. The control group received a non-medical, colorful story book, while the intervention group received an informative story book appropriate for their age. Read More

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February 2021

The Association of Dexmedetomidine on Perioperative Opioid Consumption in Children Undergoing Adenotonsillectomy With and Without Obstructive Sleep Apnea.

Anesth Analg 2021 Jan 15. Epub 2021 Jan 15.

From the Department of Anesthesiology, Perioperative and Pain Medicine, Texas Children's Hospital, Houston, Texas.

Background: Dexmedetomidine is used to reduce opioid consumption in pediatric anesthesia. However, there is conflicting evidence in pediatric adenotonsillectomy literature regarding the total perioperative opioid-sparing effects of dexmedetomidine. The aim of this study was to examine the association between dexmedetomidine and total perioperative opioid consumption in children undergoing adenotonsillectomy. Read More

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January 2021

Emergent academic skills growth in New Zealand pre-school children undergoing treatment for sleep disordered breathing: a case-control pilot study.

Sleep Med 2021 Apr 22;80:77-85. Epub 2021 Jan 22.

Department of Women's and Children's Health, University of Otago, PO Box 56, Dunedin, New Zealand. Electronic address:

Objectives: The main objective of this study was to explore the feasibility and treatment sensitivity of measures of preschool oral language and emergent literacy and numeracy for assessing developing skills of preschool children with sleep disordered breathing (SDB) in New Zealand following adenotonsillectomy.

Methods: Eight preschool children aged 3 years 1 month-4 years 5 months were recruited from a surgical waiting list and matched to controls for age (±3 months) and sex. Tasks designed to be sensitive to growth in oral language and emergent literacy and numeracy were reviewed for contextual fit, adapted as necessary for the New Zealand context, and administered before surgery (baseline), three months post-surgery, and at a seven-month follow-up alongside other measures. Read More

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Parental Perception of Weight Status for Adenotonsillectomy Patients.

Laryngoscope 2021 Feb 11. Epub 2021 Feb 11.

Department of Otolaryngology, University of Colorado School of Medicine, Aurora, Colorado, U.S.A.

Objective: Weight status can affect outcomes in pediatric adenotonsillectomy performed for obstructive sleep disordered breathing. Parents frequently underestimate their child's weight and are unaware weight status may affect adenotonsillectomy success. Accurate understanding of a child's weight status is important for shared decision making with the family and perioperative care. Read More

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February 2021

Unilateral Acupuncture Reduces Postoperative Pain Scores in Children Undergoing Adenotonsillectomy: A Randomized Controlled Trial.

J Pain Res 2021 2;14:273-283. Epub 2021 Feb 2.

Department of Anesthesia, Intensive Care and Pain Management, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.

Purpose: Acupuncture ameliorates several pain disorders including postoperative pain. This can help to decrease the need for postoperative analgesics. We aimed to evaluate the effectiveness of acupuncture as an adjuvant scheme reduce both intraoperative and postoperative analgesia needs in children undergoing adenotonsillectomy. Read More

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February 2021

Effects of an individualized analgesia protocol on the need for medical interventions after adenotonsillectomy in children: a randomized controlled trial.

BMC Anesthesiol 2021 Feb 8;21(1):41. Epub 2021 Feb 8.

Department of Anesthesia, Children's Hospital of Fudan University, 399 Wanyuan Road, Shanghai, 201102, China.

Background: It has been proposed that the dose of rescue opioids should be individually titrated to the severity of obstructive sleep apnea after adenotonsillectomy. However, a sleep study is not always available before adenotonsillectomy. This randomized, controlled and blinded trial evaluated a strategy of pain control individualized to the results of a fentanyl test, rather than the results of polysomnography, in children after adenotonsillectomy. Read More

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February 2021

Phenotypic variance in pediatric obstructive sleep apnea.

Pediatr Pulmonol 2021 Feb 5. Epub 2021 Feb 5.

Division of Pediatric Pulmonology, First Department of Pediatrics, National and Kapodistrian University of Athens School of Medicine and Aghia Sophia Children's Hospital, Athens, Greece.

It is crucial that clinicians understand what underpins the considerable phenotypic variance in pediatric obstructive sleep apnea syndrome (OSAS), if they are to implement individually tailored phenotype-based approaches to diagnosis and management. This review summarizes the current literature on how disease severity, comorbidities, genetic and environmental/lifestyle factors interact to determine the overall OSAS phenotype. The first part discusses the impact of these factors on OSAS-related morbidity in the context of otherwise healthy children, whilst the second half details children with complex conditions, particularly focusing on the anatomical and functional abnormalities predisposing to upper airway obstruction unique to each condition. Read More

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February 2021

Long-term Impact of Adenotonsillectomy on the Quality of Life of Children with Sleep-disordered breathing.

Int Arch Otorhinolaryngol 2021 Jan 4;25(1):e123-e128. Epub 2020 May 4.

Universidade Federal de Goiás, Goiânia, GO, Brazil.

 Adenotonsillectomy is the first-line treatment for obstructive sleep apnea secondary to adenotonsillar hypertrophy in children. The physical benefits of this surgery are well known as well as its impact on the quality of life (QoL), mainly according to short-term evaluations. However, the long-term effects of this surgery are still unclear. Read More

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January 2021

Defining the patterns of PAP adherence in pediatric obstructive sleep apnea: a clustering analysis using real-world data.

J Clin Sleep Med 2021 May;17(5):1005-1013

Division of Pediatric Pulmonary and Sleep Medicine, Children's National Hospital, George Washington University, Washington, DC.

Study Objectives: The implementation of positive airway pressure (PAP) therapy to treat obstructive sleep apnea in children is a complex process. PAP therapy data are highly heterogeneous in pediatrics, and the clinical management cannot be generalized. We hypothesize that pediatric PAP users can be subgrouped via clustering analysis to guide tailored interventions. Read More

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Comparison of Postoperative Analgesic Effects Between Nalbuphine and Fentanyl in Children Undergoing Adenotonsillectomy: A Prospective, Randomized, Double-Blind, Multicenter Study.

Front Pharmacol 2020 9;11:597550. Epub 2020 Dec 9.

Key Laboratory of Anesthesiology of Zhejiang Province, Department of Anesthesiology, Perioperative and Pain Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Zhejiang, China.

There is no universal agreement on optimal pharmacological regimens for pain management during surgeries. The aim of this study to compare the postoperative analgesic effects of nalbuphine with fentanyl in children undergoing adenotonsillectomy. We conducted a prospective, randomized, double-blind, non-inferiority and multicenter trial in 311 patients admitted to four different medical facilities in China from October 2017 to November 2018. Read More

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December 2020

Continuous positive airway pressure for obstructive sleep apnea in children.

Can Fam Physician 2021 Jan;67(1):21-23

Question: A 12-year-old child underwent adenotonsillectomy for treatment of obstructive sleep apnea (OSA) but continues to snore at night and struggles with attentiveness at school. The child's parent uses a continuous positive airway pressure (CPAP) machine at night and wonders whether the same therapy could be used in children.

Answer: Unlike in adults, pediatric OSA is commonly related to adenotonsillar hypertrophy and is often amenable to treatment with adenotonsillectomy. Read More

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January 2021