56,989 results match your criteria address problem

Reducing Metal/Graphene Contact Resistance via N, N-Dimethylacetamide-Assisted Clean Fabrication Process.

Nanotechnology 2021 Apr 21. Epub 2021 Apr 21.

Institute of Microelectronics Chinese Academy of Sciences, Beijing, CHINA.

Contact resistance (R) is of great importance for radio frequency (RF) applications of graphene, especially graphene field effect transistors (FETs) with short channel. FETs and transmission line model (TLM) test structures based on chemical vapor deposition grown graphene are fabricated. The effects of employing traditional lithography solvent (Acetone) and strong solvents for photo resist, such as N, N-Dimethylacetamide (ZDMAC) and N-Methyl pyrrolidone (NMP), are systematically investigated. Read More

View Article and Full-Text PDF

Eutrophication causes invertebrate biodiversity loss and decreases cross-taxon congruence across anthropogenically-disturbed lakes.

Environ Int 2021 Apr 18;153:106494. Epub 2021 Apr 18.

Institute of Hydrobiology, Chinese Academy of Science, Wuhan 430072, China. Electronic address:

Eutrophication is a major problem currently impacting many surface water ecosystems. Impacts of increased nutrient concentrations on biodiversity may differ between different scales, different organism groups, and different trophic states. Surveys at different spatial scales have suggested that biodiversity of different taxa may exhibit significant cross-taxon congruence. Read More

View Article and Full-Text PDF

A deep learning based surrogate model for the parameter identification problem in probabilistic cellular automaton epidemic models.

Comput Methods Programs Biomed 2021 Apr 1;205:106078. Epub 2021 Apr 1.

Universidade Nove de Julho, Industrial Engineering Graduate Program, PPGEP-UNINOVE, São Paulo, SP, Brazil.

Background And Objective: an accurate estimation of the epidemiological model coefficients helps understand the basic principles of disease spreading. Some studies showed that dozens of hours are needed to simulate the traditional probabilistic cellular automaton (PCA) model, and dozens of hours are spent for a fine-tuning of the system. Here, we propose a deep learning-based surrogate model to mimic a PCA model to reduce the simulations' computational time, maintaining an equivalent precision in the estimates. Read More

View Article and Full-Text PDF

Estimation of tumor parameters using neural networks for inverse bioheat problem.

Comput Methods Programs Biomed 2021 Apr 9;205:106092. Epub 2021 Apr 9.

Al-Farabi Kazakh National University, Almaty, Kazakhstan; Kazakh-British Technical University, Almaty, Kazakhstan.

Background And Objective: Some types of cancer cause rapid cell growth, while others cause cells to grow and divide at a slower rate. Certain forms of cancer result in visible growths called tumors. This work proposes an inverse estimation of the size and location of the tumor using a feedforward Neural Network (FFNN) model. Read More

View Article and Full-Text PDF

Home education for children with autism spectrum disorder during the COVID-19 pandemic: Indonesian mothers experience.

Res Dev Disabil 2021 Apr 5;114:103954. Epub 2021 Apr 5.

Department of Counseling, Faculty of Tarbiyah and Teaching, Universitas Islam Negeri Sumatera Utara, Indonesia. Electronic address:

This study aimed to explore the experiences of mothers and efforts in implementing home education for children with autism, during the COVID-19 pandemic in Indonesia. Five mothers were recruited as participants and interviewed online, as the data obtained were examined through the use of thematic analysis. Also, three main themes were shown, (1) Mothers' experience in implementing home education, as regards adaptability and burden of caregiving, (2) The constraints in home education implementation, as regards maladaptive behaviours of ASD and emerging negative emotions, (3) The efforts to alleviate barriers, as regards problem-focused and religious copings. Read More

View Article and Full-Text PDF

First mitogenome of subfamily Langiinae (Lepidoptera: Sphingidae) with its phylogenetic implications.

Gene 2021 Apr 18:145667. Epub 2021 Apr 18.

Collaborative Innovation Center of Recovery and Reconstruction of Degraded Ecosystem in Wanjiang Basin Co-founded by Anhui Province and Ministry of Education, School of Ecology and Environment, Anhui Normal University, Wuhu, Anhui 241000, China. Electronic address:

To date, a relatively complete classification of Sphingidae (Lepidoptera) has been generated, but the phylogeny of the family remains need to be fully resolved. Some phylogenetic relationships within Sphingidae still remains uncertain, especially the taxonomic status of the subfamily Langiinae and its sole included genus and species, Langia zenzeroides. To begin to address this problem, we generated nine new complete mitochondrial genomes, including that of Langia, and together with that of Theretra oldenlandiae from our previous study and 25 other Sphingidae mitogenomes downloaded from GenBank, analyzed the phylogenetic relationships of Sphingidae and investigated the mitogenomic differences among members of the Langiinae, Sphinginae, Smerinthinae and Macroglossinae. Read More

View Article and Full-Text PDF

Donor-specific elispot assay for predicting acute rejection and allograft function after kidney transplantation: a systematic review and meta-analysis.

Clin Biochem 2021 Apr 18. Epub 2021 Apr 18.

Department of Internal Medicine, Division of Nephrology and Transplantation, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands; Erasmus MC Transplantation Institute, Rotterdam, the Netherlands. Electronic address:

Acute rejection remains an important problem after kidney transplantation. Enzyme-linked immunosorbent spot (ELISPOT) assay has been investigated extensively and has shown promising results as a predictor of allograft rejection. The objective of this study was to systematically review and analyze the predictive value of the donor-specific ELISPOT assay to identify recipients at risk for acute rejection. Read More

View Article and Full-Text PDF

Large-Scale Multiagent System Tracking Control Using Mean Field Games.

Zejian Zhou Hao Xu

IEEE Trans Neural Netw Learn Syst 2021 Apr 21;PP. Epub 2021 Apr 21.

This article studies the tracking control problem with a large-scale group of agents. Unlike traditional control techniques used in multiagent systems (MASs), a new type of intelligent design is needed to handle the intractable ``Curse of Dimensionality" caused by the extremely large number of agents. To address this challenge, the mean field game (MFG) theory has been embedded into reinforcement learning to advance intelligent tracking control with large-scale MAS. Read More

View Article and Full-Text PDF

Challenges of treating mixed arterial-venous disease of lower extremities.

J Cardiovasc Surg (Torino) 2021 Apr 21. Epub 2021 Apr 21.

Division of Vascular Surgery, Department of Surgery, University of California Davis, Sacramento, CA, USA.

Introduction: Mixed arterial-venous lower extremity disease (AVLED) poses a unique challenge for clinicians. This review will outline the impact mixed AVLED has on patients and the healthcare system, by reviewing its epidemiology, diagnosis, current treatment, and the challenges encountered implementing therapies.

Evidence Acquisition: An extensive search of current literature from online sources, journals and book chapters identified the current challenges facing the treatment of mixed arterial venous ulcers of the lower extremities and potential solutions to these challenges. Read More

View Article and Full-Text PDF

Are intraoral stents effective in reducing oral toxicities caused by radiotherapy? A systematic review and meta-analysis.

J Prosthet Dent 2021 Apr 17. Epub 2021 Apr 17.

Associate Professor, Department Prosthodontics, Presidente Prudente Dental School, University of Western São Paulo (UNOESTE), Presidente Prudente, São Paulo, Brazil.

Statement Of Problem: Intraoral stents have been provided to minimize acute and chronic toxicities induced by radiotherapy, including oral mucositis, salivary changes, trismus, radiation-related caries, and osteoradionecrosis. However, a systematic review and meta-analysis is necessary to determine their effectiveness.

Purpose: The purpose of this systematic review and meta-analysis was to determine the effectiveness of intraoral stent use and determine whether these prosthetic devices can reduce radiation dosage to nontargeted oral tissues and adverse effects related to head and neck radiation. Read More

View Article and Full-Text PDF

Exponential quasi-synchronization of coupled delayed memristive neural networks via intermittent event-triggered control.

Neural Netw 2021 Feb 16;141:98-106. Epub 2021 Feb 16.

School of Automation, Huazhong University of Science and Technology, Wuhan 430074, China; Key Laboratory of Image Processing and Intelligent Control of Education Ministry of China, Wuhan 430074, China. Electronic address:

Firstly, an intermittent event-triggered control (IETC), as a combination of intermittent control and event-triggered control, is proposed. Then, the quasi-synchronization problem of coupled memristive neural networks with time-varying delays (CDMNN) is discussed under this IETC. To include more of the existing work, aperiodic intermittent control and event-triggered control with combined measurement errors are adopted in the IETC. Read More

View Article and Full-Text PDF
February 2021

Improved visualization of X-ray phase contrast volumetric data through artifact-free integrated differential images.

Phys Med 2021 Apr 18;84:80-84. Epub 2021 Apr 18.

Department of Medical Physics and Biomedical Engineering, University College London, Gower St, London WC1E 6BT, UK.

Artifacts arising when differential phase images are integrated is a common problem to several X-ray phase-based experimental techniques. The combination of noise and insufficient sampling of the high-frequency differential phase signal leads to the formation of streak artifacts in the projections, translating into poor image quality in the tomography slices. In this work, we apply a non-iterative integration algorithm proven to reduce streak artifacts in planar (2D) images to a differential phase tomography scan. Read More

View Article and Full-Text PDF

The relationship between childhood emotional abuse and depressive symptoms among Chinese college students: The multiple mediating effects of emotional and behavioral problems.

J Affect Disord 2021 Mar 31;288:129-135. Epub 2021 Mar 31.

Department of Psychiatry, University of Toronto, Toronto, ON, Canada.

Background: This study aims to explore the mediational effects of emotional and behavioral problems on the association between childhood emotional abuse and depressive symptoms among college students.

Methods: Data were drawn from 60 universities from 10 provinces in China (n=30,374). Information about childhood maltreatment, depressive symptoms, emotional and behavioral problems were gathered through the Childhood Trauma Questionnaire-Short Form (CTQ-SF), the Center for Epidemiologic Studies Depression Scale (CES-D) and the Strengths and Difficulties Questionnaire (SDQ), respectively. Read More

View Article and Full-Text PDF

A new anti-fouling polysulphone nanofiltration membrane blended by amine-functionalized MCM-41 for post treating waste stabilization pond's effluent.

J Environ Manage 2021 Apr 17;290:112649. Epub 2021 Apr 17.

Department of Environmental Science, Faculty of Natural Resources and Marine Sciences, Tarbiat Modares University, P.O. Box 46414-356, Noor, Iran.

Developing an effective and stable separation membrane for water treatment is of much interest while challenging because of the restrictions of membrane fouling and water flux reduction. To minimize this problem, in this work, highly porous and hydrophilic nanostructure of NH-modified MCM-41 (NH-MCM-41) was embedded successfully into the nanofiltration (NF) membrane body via commonly used phase inversion method. The unmodified and modified nanofiller was analyzed by Fourier Transform Infrared (FTIR) spectroscopy, X-Ray powder diffractometry (XRD), field emission scanning electron microscopy (FE-SEM), thermogravimetric analysis (TGA), and nitrogen adsorption-desorption. Read More

View Article and Full-Text PDF

Development of a structured peer mentoring program for support of parents and caregivers of children with cancer.

J Pediatr Nurs 2021 Apr 17;59:131-136. Epub 2021 Apr 17.

Department of Pediatric Medicine, Division of Nursing Research, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA. Electronic address:

Background: Parents of children newly diagnosed with cancer have increased anxiety, depression, and numerous questions. Many of these concerns can only be answered by parents who have undergone a similar experience.

Local Problem: Our institution lacked a formal parent-to-parent mentoring program for parents of children newly diagnosed with cancer. Read More

View Article and Full-Text PDF

Non-rigid image registration using a modified fuzzy feature-based inference system for 3D cardiac motion estimation.

Comput Methods Programs Biomed 2021 Apr 6;205:106085. Epub 2021 Apr 6.

Laboratory on Cardiovascular Imaging and Dynamics, Department of Cardiovascular Sciences, KU Leuven, Belgium.

Background And Objective: Non-rigid image registration is a well-established method for estimating cardiac motion on 3D echocardiographic images. However, such images have relatively poor spatio-temporal resolution making registration challenging. Some of the main challenges are extracting features relevant to the registration problem and defining a suitable geometrical transformation to be applied. Read More

View Article and Full-Text PDF

Mutually orthogonal Golay complementary sequences in the simultaneous synthetic aperture method for medical ultrasound diagnostics. An experimental study.

Ultrasonics 2021 Apr 17;115:106434. Epub 2021 Apr 17.

Ultrasound Department, Institute of Fundamental Technological Researches Polish Academy of Sciences, Poland.

Complementary Golay coded sequences (CGCS) have several advantages over conventional short pulse transmitted signals. Specifically, CGCS allow the signal-to-noise ratio (SNR) to be increased. Moreover, due to matched filtering and compression, echoes resembling the short pulse waveform with substantially higher amplitude can be obtained. Read More

View Article and Full-Text PDF

β-elemonic acid inhibits growth and triggers apoptosis in human castration-resistant prostate cancer cells through the suppression of JAK2/STAT3/MCL-1 and NF-ĸB signal pathways.

Chem Biol Interact 2021 Apr 17:109477. Epub 2021 Apr 17.

School of Pharmaceutical Sciences, Nanjing Tech University, Nanjing 210009, People's Republic of China. Electronic address:

Castration-resistant prostate cancer (CRPC) has become a significant problem in the current treatment of prostate cancer (PCa) with the characteristics of high metastatic potential, resistance and easy recurrence. The abnormal activation of JAK2/STAT3/MCL-1 and NF-κB has been confirmed as the main reason for the development of CRPC. We previously found that β-elemonic acid (β-EA) as a natural triterpene has potential anti-inflammatory and anti-osteosarcoma effects with lower toxicity. Read More

View Article and Full-Text PDF

Model reduction for initial value ODEs.

Math Biosci 2021 Apr 17:108618. Epub 2021 Apr 17.

Department of Computer Science, Wolfson Building, Parks Road, Oxford OX1 3QD, United Kingdom. Electronic address:

Many physical phenomena in biology and physiology are described by mathematical models that comprise a system of initial value ordinary differential equations. Each differential equation may often be written as the sum of several terms, where each term represents a different physical entity. A wide range of techniques, ranging from heuristic observation to mathematically rigorous asymptotic analysis, may be used to simplify these equations allowing the identification of the key phenomena responsible for a given observed behaviour. Read More

View Article and Full-Text PDF

A Bilevel Ant Colony Optimization Algorithm for Capacitated Electric Vehicle Routing Problem.

IEEE Trans Cybern 2021 Apr 20;PP. Epub 2021 Apr 20.

The development of electric vehicle (EV) techniques has led to a new vehicle routing problem (VRP) called the capacitated EV routing problem (CEVRP). Because of the limited number of charging stations and the limited cruising range of EVs, not only the service order of customers but also the recharging schedules of EVs should be considered. However, solving these two aspects of the problem together is very difficult. Read More

View Article and Full-Text PDF

Adaptive Fuzzy Decentralized Dynamic Surface Control for Switched Large-Scale Nonlinear Systems With Full-State Constraints.

IEEE Trans Cybern 2021 Apr 20;PP. Epub 2021 Apr 20.

In this study, an adaptive fuzzy decentralized dynamic surface control (DSC) problem is investigated for switched large-scale nonlinear systems with deferred asymmetric and time-varying full-state constraints. Due to the existence of additional general nonlinearities, complicated output interconnections, and full-state constraints, it is difficult to address the above control problem using existing methods. Fuzzy-logic systems are, therefore, utilized to approximate the unknown nonlinear functions, and the DSC technique is adopted to overcome the ``curse of dimensionality'' problem. Read More

View Article and Full-Text PDF

HSGAN: Hierarchical Graph Learning for Point Cloud Generation.

IEEE Trans Image Process 2021 Apr 20;PP. Epub 2021 Apr 20.

Point clouds are the most general data representations of real and abstract objects, and have a wide variety of applications in many science and engineering fields. Point clouds also provide the most scalable multi-resolution composition for geometric structures. Although point cloud learning has shown remarkable results in shape estimation and semantic segmentation, the unsupervised generation of 3D object parts still pose significant challenges in the 3D shape understanding problem. Read More

View Article and Full-Text PDF

Economic evaluation of workplace health promotion interventions focused on Lifestyle: Systematic review and meta-analysis.

J Adv Nurs 2021 Apr 19. Epub 2021 Apr 19.

Faculty of Nursing, Physiotherapy and Podiatry, University of Seville, Seville, Spain.

Aim: To identify and evaluate randomized clinical trials focusing on economic evaluation of workplace health promotion (WHP) interventions based on healthy lifestyles, physical activity and nutrition.

Design: A systematic review and meta-analysis was carried out between March and May 2019, following the PRISMA statement.

Data Sources: The literature search was conducted on Cochrane Library, Scopus, WOS and Medline databases. Read More

View Article and Full-Text PDF

Tracking single molecule dynamics in the adult Drosophila brain.

eNeuro 2021 Apr 15. Epub 2021 Apr 15.

Queensland Brain Institute, The University of Queensland, Brisbane, QLD Australia

Super-resolution microscopy provides valuable insight for understanding the nanoscale organization within living tissue, although this method is typically restricted to cultured or dissociated cells. Here, we develop a method to track the mobility of individual proteins in adult brains, focusing on a key component of the presynaptic release machinery, syntaxin1A. We show that individual syntaxin1A dynamics can be reliably tracked within neurons in the whole fly brain, and that the mobility of syntaxin1A molecules increases following conditional neural stimulation. Read More

View Article and Full-Text PDF

Literature review: Evidence-based health outcomes and perceptions of the built environment in pediatric hospital facilities.

J Pediatr Nurs 2021 Apr 16. Epub 2021 Apr 16.

Sahlgrenska University Hospital, Gothia Forum for Clinical Trials, Gothenburg, Sweden; Center for Ethics, Law, and Mental Health (CELAM), Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

Problem: The current knowledge of evidence-based design for adults is not always implemented when hospital buildings are designed. Scientific data are sparse on the effects of hospital design in pediatric settings on health outcomes in children, parents, and staff. The objective of this review is to determine the evidence-based impact of the built environment in pediatric hospital facilities on health outcomes in children, parents, and staff. Read More

View Article and Full-Text PDF

A chimeric vaccine combined with adjuvant system induces immunogenicity and protection against visceral leishmaniasis in BALB/c mice.

Vaccine 2021 Apr 16. Epub 2021 Apr 16.

Laboratório de Imunopatologia, Núcleo de Pesquisas em Ciências Biológicas (NUPEB), Universidade Federal de Ouro Preto, Ouro Preto, Brazil; Instituto Nacional de Ciência e Tecnologia em Doenças Tropicais (INCT-DT), Salvador, Brazil. Electronic address:

In Brazil, canine visceral leishmaniasis is an important public health problem due to its alarming growth. The high prevalence of infected dogs reinforces the need for a vaccine for use in prophylactic vaccination campaigns. In the present study, we evaluate the immunogenicity and protection of the best dose of Chimera A selected through the screening of cytokines production important in disease. Read More

View Article and Full-Text PDF

Impact of rehabilitation with removable complete or partial dentures on masticatory efficiency and quality of life: A cross-sectional mapping study.

J Prosthet Dent 2021 Apr 16. Epub 2021 Apr 16.

Full Professor, Department of Operative Dentistry, Endodontics and Dental Materials, Bauru School of Dentistry, University of São Paulo, Bauru, SP, Brazil. Electronic address:

Statement Of Problem: Tooth loss directly affects mastication, cognitive function, and oral health-related quality of life (OHRQoL). Complete dentures (CDs) and removable partial dentures (RPDs) represent a common oral rehabilitation approach. However, studies addressing the impact of removable dentures on replacing missing teeth are lacking. Read More

View Article and Full-Text PDF

Mapping the functional and strain diversity of the main microbiota involved in cocoa fermentation from Cote d'Ivoire.

Food Microbiol 2021 Sep 24;98:103767. Epub 2021 Feb 24.

Laboratoire d'Agriculture, Biotechnologie et Valorisation des Ressources Naturelles UFR Biosciences, University Felix Houphouet-Boigny, Abidjan, Cote D'Ivoire.

The variable quality of cocoa produced by farmers is still a problem in the value chain, strongly depending on microbial activities. We analyzed the variability of cocoa microbiota from all twelve producing regions in Cote d'Ivoire, and described the geographical distribution of isolated microbiota, using a mapping. Microbial species were identified by ribosomal genes sequencing, strains were typed by RFLP and their techno-functional capacities were further investigated. Read More

View Article and Full-Text PDF
September 2021

Harmful algal blooms and their effects in coastal seas of Northern Europe.

Harmful Algae 2021 Feb 6;102:101989. Epub 2021 Mar 6.

Finnish Environment Institute (SYKE), Marine Research Centre, Agnes Sjöbergin katu 2, 00790 Helsinki, Finland.

Harmful algal blooms (HAB) are recurrent phenomena in northern Europe along the coasts of the Baltic Sea, Kattegat-Skagerrak, eastern North Sea, Norwegian Sea and the Barents Sea. These HABs have caused occasional massive losses for the aquaculture industry and have chronically affected socioeconomic interests in several ways. This status review gives an overview of historical HAB events and summarises reports to the Harmful Algae Event Database from 1986 to the end of year 2019 and observations made in long term monitoring programmes of potentially harmful phytoplankton and of phycotoxins in bivalve shellfish. Read More

View Article and Full-Text PDF
February 2021