205,068 results match your criteria acute coronary


Emergent Hybrid Treatment of a Ruptured Scalp Arteriovenous Fistula with Eyelid involvement: Technical Note.

J Neurol Surg A Cent Eur Neurosurg 2021 Apr 12. Epub 2021 Apr 12.

Department of Neurosurgery, Center for Research and Training in Neurosurgery (CIEN), Rosario University School of Medicine, Samaritan University Hospital, Bogotá, Colombia.

Background:  Scalp arteriovenous fistulas (AVFs) are a rare vascular disease usually presenting as a progressively increasing pulsating mass in the scalp. These lesions can be associated with mild to severe complications, including congestive heart failure. If ruptures, this pathology constitutes a life-threatening medical emergency because of its potential to cause severe bleeding and acute anemia. Read More

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Cardio-pulmonary-renal interactions in ICU patients. Role of mechanical ventilation, venous congestion and perfusion deficit on worsening of renal function: Insights from the MIMIC-III database.

J Crit Care 2021 Mar 29;64:100-107. Epub 2021 Mar 29.

Medical Intensive Care Unit, APHP, Ambroise Paré Hospital, Boulogne-Billancourt, France; Versailles Saint Quentin University, France; INSERM UMR 1018, Team 5 Kidney-Heart, Centre de recherche en Epidémiologie et Santé des Populations, Villejuif, France; FHU SEPSIS (Saclay and Paris Seine Nord Endeavour to PerSonalize Interventions for Sepsis), France.

Background Mechanical ventilation (MV) in ICU patients may impact hemodynamics and renal function. We aimed to describe the interactions of MV settings, hemodynamic parameters and worsening of renal function (WRF). Methods We included adult patients admitted for the first time in the ICU from the MIMIC-III database. Read More

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Detection of Myocardial Infarction by Cardiac Magnetic Resonance in Embolic Stroke Related to First Diagnosed Atrial Fibrillation.

J Stroke Cerebrovasc Dis 2021 Apr 9;30(6):105753. Epub 2021 Apr 9.

Department of Cardiology, Dijon University Hospital, 21000 Dijon, France. Electronic address:

Introduction: Elevated troponin levels are found in a significant number of patients who are diagnosed with acute embolic stroke (AES) after first diagnosed atrial fibrillation (AF). These myocardial injuries, which are known as cardiocerebral infarction (CCI), are potentially caused by coronary embolism and correspond to simultaneous cardiac and cerebral embolisms. However, this severe condition remains poorly understood. Read More

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Impact of infrainguinal bypass tunneling technique on patency and amputation in patients with limb ischemia.

J Vasc Surg 2021 Apr 9. Epub 2021 Apr 9.

Department of Surgery, Division of Vascular Surgery, University of Southern California, Los Angeles, CA, USA. Electronic address:

Objective: To investigate the association of tunneling technique on patency and amputation in patients undergoing lower extremity bypass for limb ischemia.

Method: The National Vascular Quality Initiative database infrainguinal bypass module from 2008-2017 was queried for analysis. We excluded non-greater saphenous vein grafts, grafts using multiple segments, indication of aneurysmal disease, bypass locations outside of femoral to below knee popliteal artery or tibial arteries, and those missing data on the tunneling type and limb ischemia. Read More

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[Acute myocardial infarction caused by thrombosis of left main coronary artery. Report of two cases].

Rev Med Chil 2020 Oct;148(10):1508-1512

Hospital Militar de Santiago, Chile.

Acute myocardial infarction caused by thrombosis of left main coronary artery generate acute cardiac failure, cardiogenic shock and death. Along with the clinical history, the electrocardiogram (EKG) is the most useful tool for its recognition and timely management. Classically the EKG shows ST elevation > 1 mm in aVR or V1 with ST depression in the other leads. Read More

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October 2020

[Cardiac magnetic resonance imaging in patients with a suspected myocardial infarction and normal coronary arteries].

Rev Med Chil 2020 Oct;148(10):1406-1417

Departamento de Estadística, Facultad de Ciencias, Universidad de Valparaíso, Valparaíso, Chile.

Background: Patients hospitalized with suspected ST-segment elevation myocardial infarction (STEMI) who have normal coronary arteries (CAs) on invasive coronary angiography (ICA) may have an AMI or another acute cardiac disease that mimics it.

Aim: To evaluate the usefulness of cardiac magnetic resonance imaging (CMRI) for diagnosing conditions resembling AMI with normal CAs.

Material And Methods: We studied 424 consecutive patients admitted with suspected STEMI who underwent ICA. Read More

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October 2020

UNRAVELING THE THREAD OF UNCONTROLLED IMMUNE RESPONSE IN COVID-19 AND STEMI: AN EMERGING NEED FOR KNOWLEDGE SHARING.

Am J Physiol Heart Circ Physiol 2021 Apr 12. Epub 2021 Apr 12.

INCLIVA Health Research Institute. Valencia, Spain; Department of Medicine, School of Medicine, University of Valencia. Valencia, Spain; Centro de Investigación Biomédica en Red - Cardiovascular; Cardiology Department. Hospital Clinico Universitario. Valencia, Spain.

The outbreak of severe acute respiratory syndrome coronavirus 2 that first emerged in Wuhan in December 2019 has resulted in the devastating pandemic of coronavirus disease 2019, creating an emerging need for knowledge sharing. Meanwhile, myocardial infarction is and will probably remain the foremost cause of death in the western world throughout the coming decades. Severe deregulation of the immune system can unnecessarily expand the inflammatory response and participate in target and multiple organ failure, in infection but also in critical illness. Read More

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Predictors and potential advantages of PERT and advanced therapy use in acute pulmonary embolism.

Catheter Cardiovasc Interv 2021 Apr 12. Epub 2021 Apr 12.

Harrington Heart & Vascular Institute, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.

Objectives: We sought to examine predictors of pulmonary embolism response team (PERT) utilization and identify those who could benefit from advanced therapy.

Background: PERT and advanced therapy use remain low. Current risk stratification tools heavily weight age and comorbidities, which may not always correlate with presentation's severity. Read More

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Clinical Predictors of Heart Block During Atrioventricular Nodal Reentrant Tachycardia Ablation, a Multicenter 18 Year Experience.

J Cardiovasc Electrophysiol 2021 Apr 12. Epub 2021 Apr 12.

Department of Cardiac Electrophysiology, Northwell Health, 100 East 77th Street, New York, NY, 10075.

Background: Catheter ablation is considered the first-line treatment of symptomatic atrioventricular nodal reentrant tachycardia (AVNRT). It has been associated with a risk of heart block (HB) requiring pacemaker. This study aims to determine potential clinical predictors of complete heart block as a result AVNRT ablation. Read More

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Advances in Clinical Cardiology 2020: A Summary of Key Clinical Trials.

Adv Ther 2021 Apr 12. Epub 2021 Apr 12.

Craigavon Cardiac Centre, Southern Health and Social Care Trust, Craigavon, Northern Ireland, UK.

Introduction: Despite the challenge of a global pandemic, 2020 has been an invaluable year in cardiology research with numerous important clinical trials published or presented virtually at major international meetings. This article aims to summarise these trials and place them in clinical context.

Methods: The authors reviewed clinical trials presented at major cardiology conferences during 2020 including the American College of Cardiology, European Association for Percutaneous Cardiovascular Interventions, European Society of Cardiology, Transcatheter Cardiovascular Therapeutics and the American Heart Association. Read More

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Nutritional status and risk of contrast-associated acute kidney injury in elderly patients undergoing percutaneous coronary intervention.

Clin Exp Nephrol 2021 Apr 12. Epub 2021 Apr 12.

Department of Geriatric Medicine, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fujian Provincial Institute of Clinical Geriatrics, Fujian Key Laboratory of Geriatrics, Fujian Provincial Center for Geriatrics, Fuzhou, 350001, Fujian, China.

Background: This study aimed to investigate the connection between malnutrition evaluated by the Controlling Nutritional Status (CONUT) score and the risk of contrast-associated acute kidney injury (CA-AKI) in elderly patients who underwent percutaneous coronary intervention (PCI).

Methods: A total of 1308 patients aged over 75 years undergoing PCI was included. Based on the CONUT score, patients were assigned to normal (0-1), mild malnutrition (2-4), moderate-severe malnutrition group (≥ 5). Read More

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The positive effect of pregnancy in rheumatoid arthritis and the use of medications for the management of rheumatoid arthritis during pregnancy.

Inflammopharmacology 2021 Apr 12. Epub 2021 Apr 12.

Acharya and BM Reddy College of Pharmacy, Soldevanahalli, Bangalore, Karnataka, India.

Rheumatoid arthritis (RA) is an autoimmune systemic inflammatory disorder that is mostly characterised by progressive symmetrical joint destruction, particularly in the wrist and fingers, while it may also affect additional joints and several organs, such as the skin, heart, blood vessels, and lungs. It is identified by raised anti-rheumatoid factor and anti-cyclic citrullinated peptide antibodies. The chemical mediators involved in the activity of RA are IL-1β, TNF-α, and IL-6. Read More

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Immunoadsorption for heart failure is associated with normalization of iron metabolism.

Biomarkers 2021 Apr 12:1-21. Epub 2021 Apr 12.

Department of Internal Medicine II - Cardiology, University of Ulm Medical Center, Ulm, Germany.

In heart failure patients, early stages are associated with increased iron levels, whereas iron deficiency is a common feature of chronic heart failure (HF). We investigated the acute and long-term changes in iron metabolism in HF patients after immunoadsorption treatment and intravenous immunoglobulin (IVIG) administration. Twenty-seven patients with HF with reduced ejection fraction (HFrEF) received a single cycle of immunoadsorption followed by IVIG administration. Read More

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Methadone-Induced Polymorphic Ventricular Tachycardia Complicated by Takotsubo Cardiomyopathy in a Malnourished Patient.

J Investig Med High Impact Case Rep 2021 Jan-Dec;9:23247096211005100

Wayne State University, Detroit, MI, USA.

Takotsubo cardiomyopathy (TC) is a syndrome characterized by acute and transient regional systolic myocardial dysfunction. TC often mimics myocardial infarction without obstructive coronary disease. We present a case of a 48-year-old woman who developed TC following the onset of polymorphic ventricular tachycardia in the setting of methadone intoxication. Read More

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NMR-Based Serum and Urine Metabolomic Profile Reveals Suppression of Mitochondrial Pathways in Experimental Sepsis-Associated Acute Kidney Injury.

Am J Physiol Renal Physiol 2021 Apr 12. Epub 2021 Apr 12.

Chemistry and Biochemistry, Miami University, United States.

Sepsis-associated acute kidney injury (SA-AKI) is a significant problem in the critically ill that causes increased death. Emerging understanding of this disease implicates metabolic dysfunction in its pathophysiology. This study sought to identify specific metabolic pathways amenable to potential therapeutic intervention. Read More

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Out-of-Hospital Cardiac Arrest Does Not Affect Post-Discharge Survival in Patients With Acute Myocardial Infarction.

Circ Rep 2021 Mar 20;3(4):249-255. Epub 2021 Mar 20.

Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine Tokyo Japan.

Acute myocardial infarction (AMI) patients complicated by out-of-hospital cardiac arrest (OHCA) show poor in-hospital outcomes. However, the post-discharge outcomes of survivors of OHCA have not been well studied. Data for patients admitted to The Jikei University Kashiwa Hospital with AMI between April 2012 and March 2020 were examined retrospectively. Read More

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Association Between Physical Status and the Effects of Combination Therapy With Renin-Angiotensin System Inhibitors and β-Blockers in Patients With Acute Heart Failure.

Circ Rep 2021 Mar 13;3(4):217-226. Epub 2021 Mar 13.

Department of Cardiology, Hirakata Kohsai Hospital Osaka Japan.

This study investigated whether combination therapy (CT) with renin-angiotensin system inhibitors and β-blockers improved endpoints in acute heart failure (AHF). AHF patients were recruited to this prospective multicenter cohort study between April 2015 and August 2017. Patients were divided into 3 categories based on ejection fraction (EF), namely heart failure (HF) with reduced EF (HFrEF), HF with midrange EF (HFmrEF), and HF with preserved EF (HFpEF), and a further into 2 groups according to physical status (those who could walk independently outdoors and those who could not). Read More

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Comparison of Door-to-Balloon Time and 30-Day Mortality According to Symptom Presentation in Patients With Acute Myocardial Infarction.

Circ Rep 2021 Mar 19;3(4):194-200. Epub 2021 Mar 19.

Department of Cardiology and Nephrology, Mie University Graduate School of Medicine Tsu Japan.

We hypothesized that symptom presentation in patients with acute myocardial infarction (AMI) may affect their management and subsequent outcome. Using Rural AMI Registry data, 1,337 consecutive patients with AMI who underwent percutaneous coronary intervention were analyzed. Typical symptoms were defined as any symptoms of chest pain or pressure due to myocardial ischemia. Read More

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Radiographic case report of a heart transplanted patient suffering from COVID-19.

Heliyon 2021 Apr 3;7(4):e06688. Epub 2021 Apr 3.

Department of Diagnostic and Interventional Radiology, University Hospital, Frankfurt, Germany.

In context of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), patients with certain comorbidities and high age, as well as male sex are considered to represent the risk group for severe course of disease. Corona-virus disease 2019 (COVID-19) typical CT-patterns include bilateral, peripheral ground glass opacity (GGO), septal thickening, bronchiectasis, consolidation as well as associated pleural effusion. We report a 77-year-old heart transplanted patient with confirmed COVID-19 infection and coronary heart disease, diabetes type II and other risk factors. Read More

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Cardiac indicator CK-MB might be a predictive marker for severity and organ failure development of acute pancreatitis.

Ann Transl Med 2021 Mar;9(5):368

Department of Emergency, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Background: The prediction of severe acute pancreatitis (SAP) is the key to providing timely and targeted intensive care for acute pancreatitis (AP). The heart is one of multiple organs involved in the early stage of SAP, but the predictive ability of cardiac dysfunction for SAP remains elusive. We sought to determine if the serum levels of three cardiac indicators (CI) including N-terminal pro-brain natriuretic peptide (NT-proBNP), cardiac troponin I (cTNI), and creatine kinase myocardial band (CK-MB) at admission could predict the occurrence of SAP and the development of related organ failure (OF). Read More

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Cardiac Fibroblasts and Myocardial Regeneration.

Front Bioeng Biotechnol 2021 25;9:599928. Epub 2021 Mar 25.

Department of Biomedical Engineering, School of Medicine and School of Engineering, University of Alabama at Birmingham, Birmingham, AL, United States.

The billions of cardiomyocytes lost to acute myocardial infarction (MI) cannot be replaced by the limited regenerative capacity of adult mammalian hearts, and despite decades of research, there are still no clinically effective therapies for remuscularizing and restoring damaged myocardial tissue. Although the majority of the cardiac mass is composed of cardiomyocytes, cardiac fibroblasts (CFs) are one type of most numerous cells in the heart and the primary drivers of fibrosis, which prevents ventricular rupture immediately after MI but the fibrotic scar expansion and LV dilatation can eventually lead to heart failure. However, embryonic CFs produce cytokines that can activate proliferation in cultured cardiomyocytes, and the structural proteins produced by CFs may regulate cardiomyocyte cell-cycle activity by modulating the stiffness of the extracellular matrix (ECM). Read More

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Nomogram based on albumin and neutrophil-to-lymphocyte ratio for predicting postoperative complications after pancreaticoduodenectomy.

Gland Surg 2021 Mar;10(3):877-891

Department of Anesthesiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.

Background: The aim of this study was to identify a preoperative inflammatory marker with the most predictive value for postoperative complications after pancreaticoduodenectomy (PD). We then combined it with other perioperative variables to construct and validate a nomogram for complications after PD.

Methods: A total of 223 patients who received PD from January 2014 to July 2019 at a high-volume (>60 PDs/year) pancreatic centers in China were included in this retrospective study. Read More

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Analysis of the 60/60 Sign and Other Right Ventricular Parameters by 2D Transthoracic Echocardiography as Adjuncts to Diagnosis of Acute Pulmonary Embolism.

Cureus 2021 Mar 10;13(3):e13800. Epub 2021 Mar 10.

Interventional Cardiology, Apex Heart Institute, Ahmedabad, IND.

Introduction The 60/60 sign in 2D transthoracic echocardiography (TTE) - a combination of pulmonary acceleration time (PAT) less than 60 milliseconds and tricuspid regurgitation (TR) jet gradient of less than 60 mmHg - has been found to be specific for the diagnosis of pulmonary embolism (PE). Materials and methods An observational prospective analysis was carried out on cases of suspected PE presenting to the emergency room (ER). TTE was performed on all cases with suspected PE prior to computed tomography pulmonary angiography (CTPA). Read More

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Type 1 Acute Aortic Dissection in the Early Period After COVID-19 Infection.

Cureus 2021 Mar 7;13(3):e13751. Epub 2021 Mar 7.

Cardiovascular Surgery, University of Health Sciences, Bursa Yuksek Ihtisas Training and Research Hospital, Bursa, TUR.

The coronavirus disease 2019 (COVID-19) pandemic has resulted in over 105 million confirmed cases and over 2.3 million deaths globally as of February 3, 2021. Cardiovascular problems due to COVID-19 infection include acute coronary syndrome (due to coronary occlusion, thrombosis), myocardial damage without coronary artery disease, arrhythmias, heart failure, pericardial effusion, and thromboembolic events. Read More

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Relationship Between High Glycated Hemoglobin and Severity of Coronary Artery Disease in Type II Diabetic Patients Hospitalized With Acute Coronary Syndrome.

Cureus 2021 Mar 6;13(3):e13734. Epub 2021 Mar 6.

Cardiology, Lady Reading Hospital, Peshawar, PAK.

Introduction Diabetes mellitus (DM) is a chronic metabolic disease. It is the principal cause behind the high morbidity and mortality attributed to cardiovascular disease. This article's objective was to determine a connection between high glycated haemoglobin levels (HbA1c) and coronary artery disease (CAD). Read More

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In-hospital outcome of primary PCI for patients with acute myocardial infarction and prior coronary artery bypass grafting.

J Thorac Dis 2021 Mar;13(3):1737-1745

Heart Center & Beijing Key Laboratory of Hypertension, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.

Background: This study aims to analyze the in-hospital outcome of primary percutaneous coronary intervention (PCI) for patients with acute myocardial infarction (AMI) and prior coronary artery bypass grafting (CABG).

Methods: This was a retrospective study. From January 2011 to December 2018, the data of 78 consecutive patients (study group) with prior CABG, who received primary coronary angiography in the setting of ST-elevation myocardial infarction (STEMI) or non-ST-elevation myocardial infarction (NSTEMI), were screened. Read More

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Predictors and long-term prognosis of left ventricular aneurysm in patients with acute anterior myocardial infarction treated with primary percutaneous coronary intervention in the contemporary era.

J Thorac Dis 2021 Mar;13(3):1706-1716

Department of Cardiovascular Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.

Background: Primary percutaneous coronary intervention (PCI) has been the standard reperfusion strategy for patients with acute myocardial infarction (AMI) in the contemporary era. Meanwhile, the incidence and prognosis of left ventricular aneurysm (LVA) in AMI patients remain ambiguous. The aim of the current study is to identify the predictor and long-term prognosis of LVA in patients with acute anterior myocardial infarction. Read More

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Minimally-invasive versus transcatheter aortic valve implantation: systematic review with meta-analysis of propensity-matched studies.

J Thorac Dis 2021 Mar;13(3):1671-1683

The Royal Prince Alfred Hospital, Sydney, Australia.

Background: Minimally invasive aortic valve replacement (MiAVR) and transcatheter aortic valve implantation (TAVI) provide aortic valve replacement (AVR) by less invasive methods than conventional surgical AVR, by avoiding complete sternotomy. This study directly compares and analyses the available evidence for early outcomes between these two AVR methods.

Methods: Electronic databases were searched from inception until August 2019 for studies comparing MiAVR to TAVI, according to predefined search criteria. Read More

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Unstable angina complicated with dynamic left ventricular outflow tract obstruction.

J Cardiol Cases 2021 Apr 12;23(4):181-188. Epub 2021 Feb 12.

Department of Cardiovascular Biology and Medicine, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachidori, Chuo-ku, Niigata 951-8510, Japan.

Left ventricular outflow tract obstruction (LVOTO) complicated with unstable angina (uAP) has not been described widely, but patients with these two conditions have several problems. Differentiation of the two conditions is also often difficult because the chest symptoms are similar. Moreover, nitrates are commonly used for ischemic heart disease, but have the effect of worsening LVOTO. Read More

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