128,318 results match your criteria activity comparison


Onion-Ring-like Carbon and Nitrogen from ZIF-8 on TiO/FeO Nanostructure for Overall Electrochemical Water Splitting.

J Phys Chem Lett 2021 Jun 21:5909-5918. Epub 2021 Jun 21.

School of Mechanical Engineering, Yeungnam University, Gyeongsan 38541, Republic of Korea.

The carbon and nitrogen derived from ZIF-8 embedded in TiO/FeO (i.e., C,N-ZIF/TiFe) nanostructures exhibit superior electrocatalytic performance toward oxygen evolution reactions (OER), hydrogen evolution reactions (HER), and overall HO splitting. Read More

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Comparison of the SARS-CoV-2-inactivating activities of the differently manufactured hypochlorous acid water products with various pH.

J Water Health 2021 Jun;19(3):448-456

Department of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, 2-11 Inada, Obihiro, Hokkaido 080-8555, Japan E-mail:

The use of effective disinfectants is a key method of controlling the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Hypochlorous acid water (HAW) has a broad spectrum of virucidal activities. We previously reported that acidic electrolyzed water, one of the HAW products, had potent SARS-CoV-2-inactivating activity and showed promise as a disinfectant. Read More

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Frequency of back pain occurrence among high school youth including their physical activity.

Minerva Pediatr (Torino) 2021 Jun 21. Epub 2021 Jun 21.

Department of Adapted Physical Activity and Sport, School of Health Sciences in Katowice, Medical University of Silesia in Katowice, Katowice, Poland.

Introduction: Back pain diseases are among frequently reported health problems. Unfortunately, more often this problem also affects young people, high school students. Lifestyle that people are representing nowadays has a negative impact on their spine. Read More

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Atypical resting state functional connectivity in mild traumatic brain injury.

Brain Behav 2021 Jun 21. Epub 2021 Jun 21.

Department of Radiology, McGill University Health Centre, Montreal, Quebec, Canada.

Objectives: This study aimed to investigate changes in three intrinsic functional connectivity networks (IFCNs; default mode network [DMN], salience network [SN], and task-positive network [TPN]) in individuals who had sustained a mild traumatic brain injury (mTBI).

Methods: Resting-state functional magnetic resonance imaging (rs-fMRI) data were acquired from 27 mTBI patients with persistent postconcussive symptoms, along with 26 age- and sex-matched controls. These individuals were recruited from a Level-1 trauma center, at least 3 months after a traumatic episode. Read More

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Computational study of novel inhibitory molecule, 1-(4-((2,3)-3-amino-2-hydroxy-4-phenylbutyl)piperazin-1-yl)-3-phenylurea, with high potential to competitively block ATP binding to the RNA dependent RNA polymerase of SARS-CoV-2 virus.

J Biomol Struct Dyn 2021 Jun 21:1-19. Epub 2021 Jun 21.

Laboratory for Translational Chemistry and Drug Discovery, Department of Chemistry, Hansraj College, University of Delhi, Delhi, India.

For coronaviruses, RNA-dependent RNA polymerase (RdRp) is an essential enzyme that catalyses the replication from RNA template and therefore remains an attractive therapeutic target for anti-COVID drug discovery. In the present study, we performed a comprehensive screening for 16,776 potential molecules from recently established drug libraries based on two important pharmacophores (3-amino-4-phenylbutan-2-ol and piperazine). Based on initial assessment, 4042 molecules were obtained suitable as drug candidates, which were following Lipinski's rule. Read More

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Resistin in pregnancy: Analysis of determinants in pairs of umbilical cord blood and maternal serum.

Cytokine X 2021 Jun 4;3(2):100052. Epub 2021 Jun 4.

Department of Obstetrics and Prenatal Medicine, University Bonn Medical School, Germany.

Objective: Despite intensive research on the cytokine resistin only few studies investigated mother-newborn-pairs during healthy pregnancy and reported about interactions with clinical obstetric variables or other cytokines. Comparison of existing studies is difficult due to differences between assays, sample collection, gestational age, definition of healthy controls and patient characteristics. Furthermore, differences between rodent models and humans do not allow for a direct comparison. Read More

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Cycloartane- and Lanostane-Type Triterpenoids from the Resin of AZ-2, a Byproduct of Guayule Rubber Production.

ACS Omega 2021 Jun 4;6(23):15486-15498. Epub 2021 Jun 4.

Southwest Center for Natural Products Research, School of Natural Resources and the Environment, College of Agriculture and Life Sciences, University of Arizona, 250 E. Valencia Road, Tucson, Arizona 85706, United States.

A total of 12 new cycloartane- and lanostane-type triterpenoids including 16-deoxyargentatin A (), 16-deoxyisoargentatin A (), 7-oxoisoargentatin A (), 24--argentatin H (), 24---anisoylargentatin C (), 24---cinnamoylargentatin C (), 16-dehydroargentatin C (), 16,17(20)-didehydroargentatin C (), isoargentatin C (), isoargentatin H (), 3--quisquagenin (), and isoquisquagenin () together with 10 known triterpenoids (-) were isolated from the resin of AZ-2 obtained as a byproduct of Bridgestone guayule rubber production. The structures of new triterpenoids - and argentatin H (), which has previously been characterized as its diacetate (), were elucidated by extensive analysis of their spectroscopic data and chemical conversions, and the known compounds - were identified by comparison of their spectroscopic data with those reported. Of these, , , and exhibited weak cytotoxic activity for several cancer cell lines. Read More

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Antigonococcal Activity of (+)-Medicarpin.

ACS Omega 2021 Jun 28;6(23):15274-15278. Epub 2021 May 28.

Department of Chemistry and Biochemistry, North Carolina Central University, 1801 Fayetteville Street, Durham, North Carolina 27707, United States.

Antibiotics are the primary drugs for combating infections, but with evolving antibiotic resistance of this bacterium, new druggable molecules are needed to stem the tide of this impending public health crisis. Propolis has long been recognized for its antimicrobial properties, being composed of secondary metabolites with antibacterial potential. We herein describe the evaluation of a Jamaican multifloral propolis for antibacterial activity against The bioassay-guided evaluation of the ethyl acetate extract yielded (+)-medicarpin (), whose final structure was elucidated based on spectral analysis and comparison with the known metabolites. Read More

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Diet and Lifestyle Changes During the COVID-19 Pandemic in Ibero-American Countries: Argentina, Brazil, Mexico, Peru, and Spain.

Front Nutr 2021 2;8:671004. Epub 2021 Jun 2.

Public Health Program, Health Sciences Center, Federal University of Espírito Santo, Vitória, Brazil.

This study aimed to evaluate changes in dietary and lifestyle habits during the period of confinement due to the first wave of the COVID-19 pandemic in Ibero-American countries. A cross-sectional investigation was conducted with 6,325 participants of both genders (68% women), over 18 years of age and from five countries: Brazil ( = 2,171), Argentina ( = 1,111), Peru ( = 1,174), Mexico ( = 686), and Spain ( = 1,183). Data were collected during the year 2020, between April 01 and June 30 in Spain and between July 13 and September 26, in the other countries studied using a self-administered online survey designed for the assessment of sociodemographic, employment, physical activity, health status, and dietary habits changes. Read More

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Impact of smoking on oxidant/antioxidant status and oxidative stress index levels in serum of the university students.

J Environ Health Sci Eng 2021 Jun 26;19(1):1043-1046. Epub 2021 Apr 26.

Center for Air Pollution Research (CAPR), Institute for Environmental Research (IER), Tehran University of Medical Sciences, Tehran, 1417993359 Iran.

Background: Despite frequent warnings of irreversible side effects of smoking in public media, the consumption of cigarette is increasing dramatically in both developed and developing countries. Cigarette smoke contains different kinds of chemicals, which all capable of inducing free radical production. There are studies supporting the idea that these free radicals have adverse effects in body and causing oxidative stress. Read More

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Preparation of nanoemulsion of oil and evaluation of its larvicidal activity against a main malaria vector .

J Environ Health Sci Eng 2021 Jun 29;19(1):1025-1034. Epub 2021 Apr 29.

Department of Medical Entomology and Vector Control, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

Purpose: There is a growing need to use green and efficient larvicidal as alternatives for conventional chemicals in vector control programs. Nanotechnology has provided a promising approach for research and development of new larvicides. Larvicidal potential of a nanoemulsion of essential oil reports against . Read More

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Novel antimicrobial bioplastic based on PLA-chitosan by addition of TiO and ZnO.

J Environ Health Sci Eng 2021 Jun 10;19(1):415-425. Epub 2021 Feb 10.

Departement of Chemistry, Faculty of Mathematics and Natural Sciences, IPB University, Bogor, Indonesia.

Purpose: The purpose of this study was to develop antimicrobial bioplastics based on Poly Lactic Acid (PLA) with the addition of chitosan-ZnO, and chitosan-TiO to improve antimicrobial properties.

Methods: For the preparation of the bioplastics, PLA with chitosan-ZnO or chitosan-TiO were used. The antimicrobial activity, mechanical and thermal properties, and water vapor permeability of bioplastics were evaluated. Read More

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Comparison of proteolytic, cytotoxic and anticoagulant properties of chromatographically fractionated bromelain to un-fractionated bromelain.

Am J Transl Res 2021 15;13(5):4309-4321. Epub 2021 May 15.

Department of Surgery, University of New South Wales, St. George Hospital Kogarah, NSW, Australia.

Bromelain consisting of a number of proteolytic enzymes possess anticancer and thrombotic properties. Hence, four chromatically separated fractions were examined for their proteolytic, anticancer and antithrombotic activity. Bromelain fractions were separated using ion-exchange column chromatography. Read More

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Evaluation of Antimicrobial and Antibiofilm Activities of Copper Oxide Nanoparticles within Soft Denture Liners against Oral Pathogens.

Bioinorg Chem Appl 2021 4;2021:9939275. Epub 2021 Jun 4.

Department of Parasitology and Mycology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

Objectives: Soft denture liners provide a favorable environment for adhesion and colonization of microorganisms. This in vitro study aimed to examine the efficacy of different concentrations of copper oxide nanoparticles (CuO NPs) incorporation into soft denture liner on the biofilm formation of the microbial species.

Methods: Field Emission Scanning Electron Microscopy (FESEM) images from NPs were recorded. Read More

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The Oxidative Response of Human Monocytes to Surface Modified Commercially Pure Titanium.

Front Immunol 2021 2;12:618002. Epub 2021 Jun 2.

Department of Oral Medicine Infection and Immunity, Harvard University School of Dental medicine, Boston, MA, United States.

Cellular responses to implanted biomaterials are key to understanding osseointegration. The aim of this investigation was to determine the priming and activation of the respiratory burst activity of monocytes in response to surface-modified titanium. Human peripheral blood monocytes of healthy blood donors were separated, then incubated with surface-modified grade 2 commercially pure titanium (CPT) disks with a range of known surface energies and surface roughness for 30- or 60-min. Read More

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Metaproteomic Discovery and Characterization of a Novel Lipolytic Enzyme From an Indian Hot Spring.

Front Microbiol 2021 4;12:672727. Epub 2021 Jun 4.

Department of Microbial Biochemistry, Institute of Biochemistry and Pathobiochemistry, Ruhr University Bochum, Bochum, Germany.

Lipolytic enzymes are produced by animals, plants and microorganisms. With their chemo-, regio-, and enantio-specific characteristics, lipolytic enzymes are important biocatalysts useful in several industrial applications. They are widely used in the processing of fats and oils, detergents, food processing, paper and cosmetics production. Read More

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Changes in Metabolic Activity and Gait Function by Dual-Task Cognitive Game-Based Treadmill System in Parkinson's Disease: Protocol of a Randomized Controlled Trial.

Front Aging Neurosci 2021 4;13:680270. Epub 2021 Jun 4.

Department of Human Anatomy and Cell Science, University of Manitoba, Winnipeg, MB, Canada.

Balance and gait impairments, and consequently, mobility restrictions and falls are common in Parkinson's disease (PD). Various cognitive deficits are also common in PD and are associated with increased fall risk. These mobility and cognitive deficits are limiting factors in a person's health, ability to perform activities of daily living, and overall quality of life. Read More

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A rat model of polymicrobial infection in full-thickness excision wounds.

J Tissue Viability 2021 Jun 10. Epub 2021 Jun 10.

Department of Drug Development, Institute of Nuclear Medicine and Allied Sciences, Brig S K Mazumdar Marg, Delhi, 110054, India. Electronic address:

Aim: A reproducible animal model is required to study the pathophysiology of wound infections and for development of effective therapeutic interventions. The objective of this study was to produce an infected skin wound model utilizing the cecal microbiota in non-immunocompromised rats.

Materials And Methods: An excision wound was created on the dorsal surface of rats and inoculated with different concentration of cecal slurry (CS). Read More

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Dimethyl fumarate protects the aged brain following chronic cerebral hypoperfusion-related ischemia in rats in Nrf2-dependent manner.

Nutr Neurosci 2021 Jun 19:1-11. Epub 2021 Jun 19.

Department of Physiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

It has been stated that chronic cerebral hypoperfusion (CCH) markedly prompts neuronal damage and affects cognition. Dimethyl fumarate (DMF), a nuclear erythroid 2-related factor 2 (Nrf2) activator, represents a class of molecules exhibiting neuroprotection. We explored the effect of DMF on CCH using a model of permanent left common carotid occlusion. Read More

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Fluorine-fluorodeoxyglucose positron emission tomography for assessment of deep digital flexor tendinopathy: An exploratory study in eight horses with comparison to CT and MRI.

Vet Radiol Ultrasound 2021 Jun 20. Epub 2021 Jun 20.

School of Veterinary Medicine, University of California, Davis, Davis, California, USA.

Lesions of the deep digital flexor tendon (DDFT) are a cause for foot lameness in horses. Positron emission tomography (PET) could provide valuable information regarding the metabolic activity of these lesions. The aims of this exploratory, prospective, methods comparison study were to assess the ability of fluorine-fluorodeoxyglucose ( F-FDG) PET to detect DDFT lesions and to compare the PET findings with CT and MRI findings. Read More

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CircDIP2C ameliorates oxidized low-density lipoprotein-induced cell dysfunction by binding to miR-556-5p to induce TET2 in human umbilical vein endothelial cells.

Vascul Pharmacol 2021 Jun 17:106887. Epub 2021 Jun 17.

Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, China.

Circular RNAs (circRNAs) are a group of conserved noncoding RNAs. Recent reports reveal that circRNAs play vital parts in cardiovascular system, including atherosclerosis (AS). The present study is designed to reveal the role of circRNA DIP2C-disco interacting protein 2 homolog C (circDIP2C) in oxidized low-density lipoprotein (ox-LDL)-triggered damage of human umbilical vein endothelial cells (HUVECs). Read More

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Effective connectivity and spatial selectivity-dependent fMRI changes elicited by microstimulation of pulvinar and LIP.

Neuroimage 2021 Jun 17:118283. Epub 2021 Jun 17.

Decision and Awareness Group, Cognitive Neuroscience Laboratory, German Primate Center, Leibniz Institute for Primate Research, Kellnerweg 4, Goettingen, 37077, Germany; Department of Cognitive Neurology, University of Goettingen, Robert-Koch-Str. 40, Goettingen, 37075, Germany; Leibniz ScienceCampus Primate Cognition, Kellnerweg 4, Goettingen, 37077, Germany.

The thalamic pulvinar and the lateral intraparietal area (LIP) share reciprocal anatomical connections and are part of an extensive cortical and subcortical network involved in spatial attention and oculomotor processing. The goal of this study was to compare the effective connectivity of dorsal pulvinar (dPul) and LIP and to probe the dependency of microstimulation effects on task demands and spatial tuning properties of a given brain region. To this end, we applied unilateral electrical microstimulation in the dPul (mainly medial pulvinar) and LIP in combination with event-related BOLD fMRI in monkeys performing fixation and memory-guided saccade tasks. Read More

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The interplay between tumor necrosis factor alpha, disease activity, and depressive symptoms among Egyptian female patients with systemic lupus erythematosus.

Egypt J Immunol 2021 Jan;28(1):23-32

Department of Internal Medicine & Allergy & Clinical Immunology Unit, Ain Shams University, Cairo, Egypt.

One of the most remarkable presentations of systemic lupus erythematosus (SLE) is depression. Our aim was to elucidate the potential relationship between disease activity, depressive symptoms, and tumor necrosis factor alpha (TNF-α) in patients with SLE. Sixty female patients with SLE and thirty comparable healthy controls were recruited. Read More

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January 2021

Correcting Physiological Noise in Whole-Head Functional Near-Infrared Spectroscopy.

J Neurosci Methods 2021 Jun 16:109262. Epub 2021 Jun 16.

Stephenson School of Biomedical Engineering, University of Oklahoma, Norman, OK, USA; Institute for Biomedical Engineering, Science and Technology, University of Oklahoma, Norman, OK, USA. Electronic address:

Background: Functional near-infrared spectroscopy (fNIRS) has been increasingly employed to monitor cerebral hemodynamics in normal and diseased conditions. However, fNIRS suffers from its susceptibility to superficial activity and systemic physiological noise. The objective of the study was to establish a noise reduction method for fNIRS in a whole-head montage. Read More

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Sarcopenia, oxidative stress and inflammatory process in muscle of cirrhotic rats - Action of melatonin and physical exercise.

Exp Mol Pathol 2021 Jun 16;121:104662. Epub 2021 Jun 16.

Postgraduate in Medicine: Medical Sciences, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil; Experimental Pneumological Sciences and Inflammation Laboratory, Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil. Electronic address:

Sarcopenia is one of the most common features of cirrhosis, contributing to morbidity and mortality in this population. We aimed to evaluate the effect of melatonin (MLT) and exercise (EX) on the quadriceps muscle in rats with biliary cirrhosis induced by bile duct ligation (BDL). We used 48 males (mean weight = 300 g), divided into eight groups. Read More

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[Comparison of acquired immure deficiency syndrome-related knowledge and behavior between persons with and without human immunodeficiency virus- infection among young male students who have sex with men].

Beijing Da Xue Xue Bao Yi Xue Ban 2021 Jun;53(3):511-517

Institute of Child and Adolescent Health, Peking University School of Public Health, Beijing 100191, China.

Objective: To understand the differences between young male students who have sex with men (MSM) with and without human immunodeficiency virus (HIV)-infection in acquired immure deficiency syndrome (AIDS)-related knowledge and behavior, and to provide a scientific reference to make targeted and effective measures in AIDS prevention.

Methods: Using snow balling sampling combined with participants' referral, we conducted a questionnaire survey among 548 young MSM students (in whom there were both HIV-positive and HIV-negative) in Harbin, Tianjin, Xi'an, and Chongqing cities from April 2017 to March 2018. The chi-square test and binary Logistic regression were used to compare the differences in AIDS-related knowledge and behavior between males with and without HIV-infection. Read More

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Comparison of anterior single- and standard two-portal techniques in arthroscopic Bankart repair.

Jt Dis Relat Surg 2021 11;32(2):437-445. Epub 2021 Jun 11.

Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi Ortopedi ve Travmatoloji Anabilim Dalı, 46050 Kahramanmaraş, Türkiye.

Objectives: This study aims to compare the outcomes of patients undergoing a single anterior portal or a standard two-portal arthroscopic procedure for Bankart repair.

Patients And Methods: Between January 2015 and March 2018, a total of 71 consecutive patients (53 males and 18 females; mean age: 33.3±10. Read More

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Considerations on Activity Assay Discrepancies in Factor VIII and Factor IX Products.

J Thromb Haemost 2021 Jun 17. Epub 2021 Jun 17.

Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD, USA.

New modified coagulation factor VIII (FVIII) and factor IX (FIX) products have been designed to improve the treatment of individuals with hemophilia A and B by increasing the interval between dosing. Although these FVIII and FIX molecules have been structurally modified to improve the circulation time, the changes have also influenced their behavior in functional assays in comparison with traditional plasma-derived or recombinant coagulation factors. The assignment of potencies for these products can be problematic because discordance in factor activity values between the commonly used one-stage clotting (OC) and chromogenic substrate (CS) assays is often observed. Read More

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Emotion elicitation during music listening: Subjective self-reports, facial expression, and autonomic reactivity.

Psychophysiology 2021 Jun 18:e13884. Epub 2021 Jun 18.

Facultad de Ciencias de la Salud, Departamento de Psicología Básica, Clínica y Psicobiología, Universitat Jaume I, Castelló de la Plana, Castellón, Spain.

The use of music as emotional stimuli in experimental studies has grown in recent years. However, prior studies have mainly focused on self-reports and central measures, with a few works exploring the time course of psychophysiological correlates. Moreover, most of the previous research has been carried out either from the dimensional or categorical model but not combining both approaches to emotions. Read More

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Comparative transcriptomic and physiological analyses of weedy rice and cultivated rice to identify vital differentially expressed genes and pathways regulating the ABA response.

Sci Rep 2021 Jun 18;11(1):12881. Epub 2021 Jun 18.

Key Laboratory of Northern Japonica Rice Genetics and Breeding, Ministry of Education and Liaoning Province, Key Laboratory of Northeast Rice Biology and Genetics and Breeding, Ministry of Agriculture, Rice Research Institute of Shenyang Agricultural University, Shenyang, 110866, China.

Weedy rice is a valuable germplasm resource characterized by its high tolerance to both abiotic and biotic stresses. Abscisic acid (ABA) serves as a regulatory signal in plant cells as part of their adaptive response to stress. However, a global understanding of the response of weedy rice to ABA remains to be elucidated. Read More

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