132 results match your criteria acnes describe

C1-C2 arthrodesis after spontaneous spondylodiscitis: Case report and literature analysis.

Surg Neurol Int 2018 22;9:14. Epub 2018 Jan 22.

GSpine4, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.

Background: () is a microaerophilic anaerobic Gram-positive rod responsible for acne vulgaris. Although it is often considered to be a skin contaminant, it may act as a virulent agent in implant-associated infections. Conversely, spontaneous infectious processes have been rarely described. Read More

View Article and Full-Text PDF
January 2018

Virome and bacteriome characterization of children with pneumonia and asthma in Mexico City during winter seasons 2014 and 2015.

PLoS One 2018 15;13(2):e0192878. Epub 2018 Feb 15.

Departamento de Investigación en Virología, Instituto Nacional de Enfermedades Respiratorias Ismael Cosio Villegas, Mexico City, Mexico.

Background: Acute asthma exacerbations and pneumonia are important causes of morbidity and mortality in children and may coexist in the same children, although symptom overlap may lead to difficulties in diagnosis. Microbial and viral diversity and differential abundance of either may play an important role in infection susceptibility and the development of acute and chronic respiratory diseases.

Objectives: To describe the virome and bacteriome present in the upper respiratory tract of hospitalized children with a clinical diagnosis of asthma and pneumonia during an acute exacerbation and an acute respiratory illness ARI episode respectively. Read More

View Article and Full-Text PDF

[Periodontal microbiota and microorganisms isolated from heart valves in patients undergoing valve replacement surgery in a clinic in Cali, Colombia].

Biomedica 2017 Dec 1;37(4):516-525. Epub 2017 Dec 1.

Grupo de Investigación en Ciencias Básicas y Clínicas de la Salud, Pontificia Universidad Javeriana - Cali, Cali, Colombia.

Introduction: Periodontitis is an infectious disease that affects the support tissue of the teeth and it is associated with different systemic diseases, including cardiovascular disease. Microbiological studies facilitate the detection of microorganisms from subgingival and cardiovascular samples.

Objective: To describe the cultivable periodontal microbiota and the presence of microorganisms in heart valves from patients undergoing valve replacement surgery in a clinic in Cali. Read More

View Article and Full-Text PDF
December 2017

The human skin microbiome.

Nat Rev Microbiol 2018 03 15;16(3):143-155. Epub 2018 Jan 15.

Microbial Genomics Section, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

Functioning as the exterior interface of the human body with the environment, skin acts as a physical barrier to prevent the invasion of foreign pathogens while providing a home to the commensal microbiota. The harsh physical landscape of skin, particularly the desiccated, nutrient-poor, acidic environment, also contributes to the adversity that pathogens face when colonizing human skin. Despite this, the skin is colonized by a diverse microbiota. Read More

View Article and Full-Text PDF

A Case of Atypical Synovitis-Acne-Pustulosis-Hyperostosis-Osteitis (SAPHO) Syndrome Presenting With Osteomyelitis of the Clavicle.

WMJ 2017 Jun;116(2):87-88

Department of Internal Medicine-Pediatrics Infectious Disease, Tufts Medical Center, Boston, Massachusetts.

Synovitis-acne-pustulosis-hyperostosis-osteitis (SAPHO) syndrome is considered after exclusion of infection and arthritis; however, microbial infection may be present in osteoarticular lesions of these patients. Chronic osteomyelitis and associated bacterial infection were detected in a recurrent osteoarticular lesion in an adolescent patient with a history of clavicle pain, who complained of recurrent swelling in the left clavicle. Most pediatric case reports of SAPHO syndrome describe patients with associated skin conditions. Read More

View Article and Full-Text PDF

Over a Decade of recA and tly Gene Sequence Typing of the Skin Bacterium Propionibacterium acnes: What Have We Learnt?

Andrew McDowell

Microorganisms 2017 Dec 21;6(1). Epub 2017 Dec 21.

Northern Ireland Centre for Stratified Medicine, School of Biomedical Sciences, Ulster University, Londonderry BT47 6SB, UK.

The Gram-positive, anaerobic bacterium forms part of the normal microbiota on human skin and mucosal surfaces. While normally associated with skin health, is also an opportunistic pathogen linked with a range of human infections and clinical conditions. Over the last decade, our knowledge of the intraspecies phylogenetics and taxonomy of this bacterium has increased tremendously due to the introduction of DNA typing schemes based on single and multiple gene loci, as well as whole genomes. Read More

View Article and Full-Text PDF
December 2017

Susceptibility of Enterococcus faecalis and Propionibacterium acnes to antimicrobial photodynamic therapy.

J Photochem Photobiol B 2018 Jan 5;178:545-550. Epub 2017 Dec 5.

Universidade Estadual Paulista (Unesp), Faculdade de Ciências Farmacêuticas, Araraquara. Rodovia Araraquara-Jaú, Km1, Campus Ville, Araraquara, SP, CEP 14800-903, Brazil. Electronic address:

Bacterial resistance to available antibiotics nowadays is a global threat leading researchers around the world to study new treatment modalities for infections. Antimicrobial photodynamic therapy (aPDT) has been considered an effective and promising therapeutic alternative in this scenario. Briefly, this therapy is based on the activation of a non-toxic photosensitizing agent, known as photosensitizer (PS), by light at a specific wavelength generating cytotoxic singlet oxygen and free radicals. Read More

View Article and Full-Text PDF
January 2018

Lateral Cutaneous Nerve Entrapment Syndrome (LACNES): A previously unrecognized cause of intractable flank pain.

Scand J Pain 2017 10 5;17:211-217. Epub 2017 Nov 5.

Department of Surgery, Máxima Medical Center, Veldhoven, The Netherlands; SolviMáx, Center of Expertise for ACNES, Center of Excellence for Chronic Abdominal Wall and Groin Pain, Máxima Medical Center, Eindhoven, The Netherlands.

Background And Aims: Chronic abdominal pain may occasionally be due to terminal endings of intercostal nerves (ACNES, abdominal cutaneous nerve entrapment syndrome) that are entrapped in the abdominal wall. Spontaneous neuropathic flank pain may also be caused by involvement of branches of these intercostal nerves. Aim is to describe a series of patients with flank pain due to nerve entrapment and to increase awareness for an unknown condition coined Lateral Cutaneous Nerve Entrapment Syndrome (LACNES). Read More

View Article and Full-Text PDF
October 2017

Targeted intervention of acute postoperative infection after rotator cuff repair results in good functional outcomes.

Knee Surg Sports Traumatol Arthrosc 2018 Jan 11;26(1):285-291. Epub 2017 Oct 11.

Lovisenberg Diaconal Hospital, Lovisenberggt. 17, 0456, Oslo, Norway.

Purpose: The primary goal of this retrospective review of a prospective database was to document the functional results after acute postoperative deep infection following rotator cuff repair in a single orthopaedic unit over a period of 5 years. Secondary goals were to document the effect of infection on healing of the cuff repair and to describe its incidence, diagnostic challenges, pathogens and management.

Methods: Patients undergoing arthroscopic rotator cuff repair were prospectively registered from 2010 to 2014. Read More

View Article and Full-Text PDF
January 2018

Constrictive pericarditis caused by Cutibacterium (Propionibacterium) acnes: A case report and review of literature.

IDCases 2017 28;10:79-82. Epub 2017 Sep 28.

Department of Medicine; section of Infectious Diseases, Hospital Unit Vest, Herning, Denmark.

Constrictive and effusive-constrictive pericarditis are rare cardiac disorders. Only rarely are the conditions caused by purulent infection, and even more infrequently by anaerobe bacteria. We describe a case of constrictive - and effusive-constrictive pericarditis due to formerly in a 75-year old, immunocompetent and previously healthy patient without any predisposition. Read More

View Article and Full-Text PDF
September 2017

Propionibacterium avidum: A Virulent Pathogen Causing Hip Periprosthetic Joint Infection.

Clin Infect Dis 2018 01;66(1):54-63

Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Switzerland.

Background: Propionibacteria are important members of the human skin microbiota, but are also opportunistic pathogens associated with periprosthetic joint infection (PJI). While the role of Propionibacterium acnes in PJI has been widely described, insight into the capacity of Propionibacterium avidum to cause PJI is limited.

Methods: An unusual cluster of 4 hip PJIs caused by P. Read More

View Article and Full-Text PDF
January 2018

Propionibacterium acnes as an emerging pathogen in skull base osteomyelitis: A case series.

Laryngoscope 2018 02 10;128(2):332-335. Epub 2017 Oct 10.

Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, U.S.A.

Skull base osteomyelitis (SBO) is recognized as a potentially life-threatening infection that has been classically attributed to Pseudomonas aeruginosa. However, growing data shows that the bacteriology of SBO is changing. Traditionally thought of as commensal bacterium, P. Read More

View Article and Full-Text PDF
February 2018

Propionibacterium Acnes: Cause of Cerebrospinal Fluid Shunt Infection.

Pediatr Infect Dis J 2018 06;37(6):e168-e169

Paediatric Infectious Diseases Unit, Department of Paediatrics Hospital Santa Maria, Lisbon, Portugal, Academic Medical Centre.

Infection after implantation of ventriculo-peritoneal shunts is associated with significant morbidity and mortality. We describe a 9-year-old girl with Propionibacterium acnes shunt infection with negative cerebrospinal fluid cultures, diagnosed by broad-range 16S-rRNA gene polymerase chain reaction. This case supports the use of this molecular diagnostic technique in shunt infections, where the offending pathogens are difficult to culture using traditional methods. Read More

View Article and Full-Text PDF

Characterization of a Propionibacterium acnes Surface Protein as a Fibrinogen-Binding Protein.

Sci Rep 2017 07 25;7(1):6428. Epub 2017 Jul 25.

Université Sorbonne Paris Descartes, Faculté de Médecine, INSERM CNRS UMR8104, Institut Cochin U1016, Laboratoire de Dermatologie-CNR Syphilis, Paris, France.

Propionibacterium acnes (P. acnes) is a major skin-associated bacterium that was long considered commensal, until several studies revealed it to be an opportunistic pathogen. We investigated the ability of P. Read More

View Article and Full-Text PDF

Association between post-craniotomy Propionibacterium acnes infection and dural implants: a case-control study.

J Hosp Infect 2017 Dec 8;97(4):389-396. Epub 2017 Jul 8.

University Hospitals of North Midlands NHS Trust, UK.

Background: In 2011, 15 deep-seated Propionibacterium acnes infections were identified in patients following craniotomies in a hospital in the UK.

Aim: To describe the outbreak and report findings from the investigation undertaken in order to identify the source and risk factors and inform control measures.

Methods: Data were obtained from hospital clinical records and included patient and surgical variables. Read More

View Article and Full-Text PDF
December 2017

Groin Pain Characteristics and Recurrence Rates: Three-year Results of a Randomized Controlled Trial Comparing Self-gripping Progrip Mesh and Sutured Polypropylene Mesh for Open Inguinal Hernia Repair.

Ann Surg 2018 06;267(6):1028-1033

Department of General Surgery, Máxima Medical Centre, Veldhoven/Eindhoven, the Netherlands.

Objective: The aim of this study was to investigate long-term groin pain and inguinal hernia recurrence rates of 2 types of mesh and to describe the evolution of postoperative groin sensory disturbances.

Summary Of Background Data: Some patients with an inguinal hernia develop chronic pain following open mesh insertion. Previous trials comparing a semi-resorbable, self-gripping Progrip mesh with a standard sutured polypropylene mesh found conflicting results regarding recurrence rates and residual groin pain. Read More

View Article and Full-Text PDF

Understanding the role of Propionibacterium acnes in acne vulgaris: The critical importance of skin sampling methodologies.

Clin Dermatol 2017 Mar - Apr;35(2):118-129. Epub 2016 Oct 27.

Department of Medical Biosciences/Pathology, Umeå University, Umeå, Sweden. Electronic address:

Acne vulgaris is a chronic inflammatory skin condition classified by the Global Burden of Disease Study as the eighth most prevalent disease worldwide. The pathophysiology of the condition has been extensively studied, with an increase in sebum production, abnormal keratinization of the pilosebaceous follicle, and an inflammatory immune response all implicated in its etiology. One of the most disputed points, however, is the role of the gram-positive anaerobic bacterium Propionibacterium acnes in the development of acne, particularly when this organism is also found in normal sebaceous follicles of healthy skin. Read More

View Article and Full-Text PDF
November 2017

Characterisation of microbial communities within aggressive prostate cancer tissues.

Infect Agent Cancer 2017 13;12. Epub 2017 Jan 13.

Genetic Epidemiology Laboratory, Department of Pathology, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, VIC, Australia 3010.

Background: An infectious aetiology for prostate cancer has been conjectured for decades but the evidence gained from questionnaire-based and sero-epidemiological studies is weak and inconsistent, and a causal association with any infectious agent is not established. We describe and evaluate the application of new technology to detect bacterial and viral agents in high-grade prostate cancer tissues. The potential of targeted 16S rRNA gene sequencing and total RNA sequencing was evaluated in terms of its utility to characterise microbial communities within high-grade prostate tumours. Read More

View Article and Full-Text PDF
January 2017

Future surgery after revision shoulder arthroplasty: the impact of unexpected positive cultures.

J Shoulder Elbow Surg 2017 Jun 10;26(6):975-981. Epub 2017 Jan 10.

Department of Orthopaedic Surgery, The Rothman Institute-Thomas Jefferson University Hospital, Philadelphia, PA, USA. Electronic address:

Background: The clinical implications and treatment of unexpected positive cultures (UPCs) in revision shoulder arthroplasty are not well defined. The purpose of this study was to describe results of patients with and without UPCs after revision shoulder arthroplasty.

Methods: A single institutional database was used to retrospectively identify all revision shoulder arthroplasties performed between January 1, 2011, and December 31, 2013. Read More

View Article and Full-Text PDF

Propionibacterium acnes endocarditis: a case series.

Clin Microbiol Infect 2017 Jun 3;23(6):396-399. Epub 2017 Jan 3.

Department of Infectious Disease, Cleveland Clinic, Cleveland, OH, USA. Electronic address:

Objectives: Propionibacterium acnes remains a rare cause of infective endocarditis (IE). It is challenging to diagnose due to the organism's fastidious nature and the indolent presentation of the disease. The purpose of this study was to describe the clinical presentation and management of P. Read More

View Article and Full-Text PDF

Recognition of Propionibacterium acnes by human TLR2 heterodimers.

Int J Med Microbiol 2017 Feb 12;307(2):108-112. Epub 2016 Dec 12.

Freie Universität Berlin, Institute of Pharmacy (Pharmacology and Toxicology), Berlin, Germany. Electronic address:

Propionibacterium acnes has been considered as a crucial contributor to the pathogenesis of acne vulgaris. The interaction between P. acnes and the host is mainly mediated by Toll like receptor (TLR) 2 recognition. Read More

View Article and Full-Text PDF
February 2017

Chronic post-operative iris prosthesis endophthalmitis in a patient with traumatic aniridia: a case report.

BMC Ophthalmol 2016 Nov 9;16(1):197. Epub 2016 Nov 9.

Department of Ophthalmology and Visual Neurosciences, University of Minnesota, 420 Delaware Street SE, MMC 493, Minneapolis, MN, 55455, USA.

Background: Post-operative endophthalmitis is a serious complication of intraocular surgery which may present acutely or chronically. Chronic post-operative endophthalmitis is characterized by decreased visual acuity, mild pain, and low-grade uveitis several weeks or months after intraocular surgery which may be responsive to corticosteroids, but recur upon tapering. Low virulence organisms such as Propionibacterium acnes are the most common culprit organisms, and treatment most often consists of both intravitreal antibiotic injections and surgery. Read More

View Article and Full-Text PDF
November 2016

Emendation of Propionibacterium acnes subsp. acnes (Deiko et al. 2015) and proposal of Propionibacterium acnes type II as Propionibacterium acnes subsp. defendens subsp. nov.

Int J Syst Evol Microbiol 2016 12 25;66(12):5358-5365. Epub 2016 Sep 25.

Centre for Infection & Immunity, School of Medicine, Dentistry & Biomedical Sciences, Queen's University, Belfast, UK.

Recently, it has been proposed that strains of Propionibacterium acnes from the type III genetic division should be classified as P. acnessubsp. elongatum subsp. Read More

View Article and Full-Text PDF
December 2016

Strains of the Propionibacterium acnes type III lineage are associated with the skin condition progressive macular hypomelanosis.

Sci Rep 2016 08 24;6:31968. Epub 2016 Aug 24.

Centre for Infection &Immunity, School of Medicine, Dentistry &Biomedical Sciences, Queen's University, Belfast, UK.

Progressive macular hypomelanosis (PMH) is a common skin disorder that causes hypopigmentation in a variety of skin types. Although the underlying aetiology of this condition is unclear, there is circumstantial evidence that links the skin bacterium Propionibacterium acnes to the condition. We now describe the first detailed population genetic analysis of P. Read More

View Article and Full-Text PDF

Propionibacterium avidum as an Etiological Agent of Prosthetic Hip Joint Infection.

PLoS One 2016 29;11(6):e0158164. Epub 2016 Jun 29.

School of Medical Sciences, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.

Propionibacterium acnes is well-established as a possible etiologic agent of prosthetic joint infections (PJIs). Other Propionibacterium spp. have occasionally been described as a cause of PJIs, but this has not previously been the case for P. Read More

View Article and Full-Text PDF

Saddle nose with sarcoidosis: "A great imitator" of relapsing polychondritis.

Mod Rheumatol 2018 Nov 20;28(6):1053-1057. Epub 2016 Jun 20.

d Department of Human Pathology , Tokyo Medical and Dental University , Tokyo , Japan.

Sarcoidosis is a systemic granulomatous disease that can affect any organ including the nose. Nasal crusting and congestion are common nasal symptoms of sarcoidosis, whereas cases of saddle-nose deformity are rarely reported. We describe here a case of sarcoidosis that presented with saddle nose resembling relapsing polychondritis. Read More

View Article and Full-Text PDF
November 2018

Propionibacterium Acnes Brain Abscess in an Immunocompetent Man in the Absence of Prior Neurosurgery.

S D Med 2016 Feb;69(2):71-3

Propionibacterium acnes is a rare, but established, cause of intracranial abscesses. We describe a case of P. acnes brain abscess in an immunocompetent man without prior neurosurgery. Read More

View Article and Full-Text PDF
February 2016

Discovery of a Novel Seminal Fluid Microbiome and Influence of Estrogen Receptor Alpha Genetic Status.

Sci Rep 2016 Mar 14;6:23027. Epub 2016 Mar 14.

Bond Life Sciences Center, University of Missouri, Columbia, MO 65211 USA.

Bacteria harbored in the male reproductive system may influence reproductive function and health of the male and result in developmental origins of adult health and disease (DOHaD) effects in his offspring. Such effects could be due to the seminal fluid, which is slightly basic and enriched with carbohydrates; thereby, creating an ideal habitat for microbes or a potential seminal fluid microbiome (SFM). Using wild-type (WT) and estrogen receptor-alpha (ESR1) knockout (KO) male mice, we describe a unique SFM whose inhabitants differ from gut microbes. Read More

View Article and Full-Text PDF

Hyaluronidase in Clinical Isolates of Propionibacterium acnes.

Int J Bacteriol 2015 18;2015:218918. Epub 2015 Feb 18.

Division of Infectious Diseases, Department of Medicine, Mayo Clinic, Rochester, MN, USA; Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.

Objectives. We sought to describe the prevalence of a hyaluronidase gene and hyaluronidase production in 197 clinical isolates of P. acnes; we assessed kinetics of hyaluronidase production in a subset of three isolates. Read More

View Article and Full-Text PDF
February 2016

Compressive spinal epidural mass caused by Propionibacterium acnes.

Spine J 2016 05 22;16(5):e347-51. Epub 2015 Dec 22.

Department of Orthopaedics, Division of Spine Surgery-Adult Spinal Deformity Service, Warren Alpert Medical School of Brown University, 593 Eddy St, Providence, RI 02903, USA.

Background Context: Propionibacterium acnes is a gram-positive and facultative anaerobe bacillus that is found within sebaceous follicles of the human skin and recognized as a cause of infections after spinal surgery. To our knowledge, there has been no previously reported case of symptomatic compressive chronic inflammatory epidural mass caused by P. acnes in a patient with no prior spinal procedures. Read More

View Article and Full-Text PDF