39 results match your criteria achillea wilhelmsii


A Simple Method for Developing a Hand-Drawn Paper-Based Sensor for Mercury; Using Green Synthesized Silver Nanoparticles and Smartphone as a Hand-Held-Device for Colorimetric Assay.

Glob Chall 2021 Apr 15;5(4):2000099. Epub 2021 Feb 15.

Pharmaceutical Sciences Research Center Health institute Kermanshah University of Medical Sciences Kermanshah 6715847141 Iran.

Mercury ions are highly toxic at trace levels, and its pollution has posed a significant threat to the environment and public health, where current detection methods mainly require laborious operation and expensive instrumentation. Herein, a simple, cost-effective, instrument-free approach for selective detection of Hg based on a hand-drawn paper-based naked-eye colorimetric device is developed. To develop a hand-drawn paper-based device, a crayon is used to build hydrophobic barriers and a paper puncher is applied to obtain patterns as a sensing zone. Read More

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Hydro-alcoholic Extract of C. Koch Reduces the Expression of Cell Death-Associated Genes while Inducing DNA Damage in HeLa Cervical Cancer Cells.

Iran J Med Sci 2020 Sep;45(5):359-367

Cellular and Molecular Research Center, Resistant Tuberculosis Institute, Zahedan University of Medical Sciences, Zahedan, Iran.

Background: C. Koch hydroalcoholic extract (AWHE) is proven to induce cell death. Previous studies suggested that AWHE is an effective inhibitor against the proliferation of prostate cancer cells. Read More

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September 2020

Hydroalcoholic Extract Induces Apoptosis and Alters and Gene Expression in Hela Cervical Cancer Cells.

Rep Biochem Mol Biol 2019 Oct;8(3):318-325

Department of Chemistry, Iran University of Science and Technology; Tehran, Iran.

Background: Inappropriate activation of the proto-oncogene LIN28B and inactivation of the p53 tumor suppressor, have been shown to have a critical role in tumorigenesis. Previous research has shown therapeutic potential for the use of herbal plants as an alternative strategy for cancer treatment. C. Read More

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October 2019

Heavy metal concentrations in roadside plants (Achillea wilhelmsii and Cardaria draba) and soils along some highways in Hamedan, west of Iran.

Environ Sci Pollut Res Int 2020 Apr 4;27(12):13301-13314. Epub 2020 Feb 4.

Department of Agriculture, Sayyed Jamaleddin Asadabadi University, Asadabad, Iran.

The present study was conducted to analyze the effects of traffic volumes on Cd, Cu, Pb, Ni, and Zn contents in roadside soils and in two dominant herbaceous species (Achillea wilhelmsii and Cardaria draba) along highways and to evaluate the dynamic characteristics of these elements and their accumulation by the aerial parts and roots of these herbaceous species. The plant samples were collected along 700 m of a 9-km segment of each of the three major highways in Hamedan Province (West Iran) with different traffic volumes: Hamedan-Goltapeh (HG), Hamedan-Razan (HR), and Hamedan-Kermanshah (HK). The results indicated that the mean contents of Cd, Cu, Pb, Ni, and Zn in the soil samples were 0. Read More

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A Detailed Biological and Chemical Investigation of Sixteen Achillea Species' Essential Oils via Chemometric Approach.

Chem Biodivers 2020 Mar 20;17(3):e1900484. Epub 2020 Feb 20.

Department of Pharmacognosy, Faculty of Pharmacy, Dicle University, 21280, Diyarbakir, Turkey.

Representatives of the Achillea genus are widely used as foods or nutraceuticals. Considering the increasing demand for herbal dietary supplements with health promoting effects, the objective of this research was to evaluate the chemical composition and biological activities of the essential oils obtained from sixteen Achillea species (A. biebersteinii, A. Read More

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Oral acute and sub-acute toxic effects of hydroalcoholic Terminalia chebula Retz and Achillea wilhelmsii extracts in BALB/c mice.

Biomedicine (Taipei) 2019 Dec 21;9(4):25. Epub 2019 Nov 21.

Department of Pathology, School of Veterinary Medicine, Islamic Azad University, Shahrekord, Iran.

Background: This study examined the acute and sub-acute toxic effects of Terminalia chebula and Achillea wilhelmsii extracts on the murine model.

Methods: In both phases, mice were assigned to intervention and control groups. At the end of study, the liver, kidney, and heart tissues were collected for histopathological studies. Read More

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December 2019

Efficacy and safety of Achillea wilhelmsii C. Koch capsules on symptom severity and quality of life in patients with irritable bowel syndrome: a randomized, placebo-controlled clinical trial.

J Complement Integr Med 2019 Aug 23;16(4). Epub 2019 Aug 23.

Pharmaceutical Sciences Research Center, Faculty of Pharmacy, Kermanshah University of Medical Sciences, Kermanshah, Iran.

Background Irritable bowel syndrome (IBS) is one of the most common digestive diseases. The aim of this clinical trial was to determine the effectiveness of Achillea wilhelmsii C. Koch on the symptom severity and quality of life (QOL) in patients with IBS. Read More

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Therapeutic effects of hydro-alcoholic extract of Achillea wilhelmsii C. Koch on indomethacin-induced gastric ulcer in rats: a proteomic and metabolomic approach.

BMC Complement Altern Med 2019 Aug 7;19(1):205. Epub 2019 Aug 7.

Department of Basic Sciences, Faculty of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Background: Gastric ulcer is one of the most prevalent diseases worldwide. In Iranian folk medicine, Achillea wilhelmsii (AW) is used as a treatment for gastric ulcer. Previous reports also mentioned Antiulcerogenic properties for this herbal plant. Read More

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Efficacy and safety of a standardized extract from Achillea wilhelmsii C. Koch in patients with ulcerative colitis: A randomized double blind placebo-controlled clinical trial.

Complement Ther Med 2019 Aug 2;45:262-268. Epub 2019 May 2.

Pharmaceutical Sciences Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran. Electronic address:

Background: Using Achillea wilhelmsii as a dietary supplement for gastrointestinal disorders is common in Persian traditional medicine. Its anti-inflammatory, anti-spasmodic and antibacterial properties have been proven by different in vitro and in vivo studies, yet it has not been evaluated in a controlled clinical trial.

Aim: This study intended to evaluate the efficacy and safety of A. Read More

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Elemental Characterization of Medicinal Plants and Soils from Hazarganji Chiltan National Park and Nearby Unprotected Areas of Balochistan, Pakistan.

J Oleo Sci 2019 ;68(5):443-461

Institute of Biochemistry, University of Balochistan.

The aim of this work was to evaluate the variability in elemental composition of seven medicinal plants and their respective soils belonging to protected and nearby unprotected sites of the Hazarganji Chiltan National Park. The medical plants under study were Achillea wilhelmsii C. Koch, Peganum harmala Linn, Sophora mollis (Royle) Baker, Perovskia atriplicifolia Benth, Seriphidium quettense (Podlech. Read More

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A screening of growth inhibitory activity of Iranian medicinal plants on prostate cancer cell lines.

Biomedicine (Taipei) 2018 Jun 28;8(2). Epub 2018 May 28.

Cellular and Molecular Research Center, Basic Health Sciences Institute, Shahrekord University of Medical Sciences, Shahrekord, Iran.

Background: Prostate cancer has been known as one of the most common malignancy in the men and it is therefore very important to prevent and treat this cancer. In this study, the anticancer effects of 20 species of medicinal plants in Iran, especially those grown in Chaharmahal and Bakhtiari province, were investigated on prostate cancer cell lines to identify potential natural alternatives for the development of prostate cancer anticancer drugs.

Methods: The plants were gathered from Chaharmahal va Bakhtyari and their aerial parts extracted through maceration method using ethanol 70%. Read More

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Cardioprotective effects of on the isolated rat heart in ischemia-reperfusion.

J Tradit Complement Med 2017 Oct 6;7(4):501-507. Epub 2017 Feb 6.

Department of Clinical Biochemistry, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Context: There are some reports about protective effects of on the heart.

Objective: We investigated the effect of extract on cardiac function during ischemia-reperfusion (I/R) injury in the isolated rat heart.

Materials And Methods: 60 male Wistar rats were randomly divided into 6 groups; 1: Control group, 2: Control-ischemia (CI) 3: vitamin C (10 mg/kg), 4-6: Extract groups (E 100, E 200 and E 400 mg/kg). Read More

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October 2017

Repellency Effect of Essential Oils of some Native Plants and Synthetic Repellents against Human Flea, (Siphonaptera: Pulicidae).

J Arthropod Borne Dis 2017 Mar 14;11(1):105-115. Epub 2017 Mar 14.

Department of Medical Entomology and Vector Control, Faculty of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.

Background: Fleas are important vectors of human and animal disease, and control measures for protection against their bites and flea-borne diseases are necessary.

Methods: The essential oils (EOs) of four native medicinal plants, , , and were isolated by hydrodistillation technique and analyzed by GC-MC. The repellent activity of EOs and synthetic compounds, DEET and permethrin, were assayed on human subjects against field collected fleas. Read More

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Effect of extract on expression of the human telomerase reverse transcriptase mRNA in the PC3 prostate cancer cell line.

Biomed Rep 2017 Sep 31;7(3):251-256. Epub 2017 Jul 31.

Department of Clinical Biochemistry, School of Medicine, Zahedan University of Medical Sciences, Zahedan 9816743175, Iran.

Evidence has indicated that human telomerase reverse transcriptase (hTERT) was overexpressed in prostate cancer (PCa). (AW) is a plant that has been traditionally used for its medicinal properties. The aim of current study was to evaluate the effects of AW extract on a PCa cell line. Read More

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September 2017

Inhibition of Phosphodiesterase 5 and Increasing the Level of Cyclic Guanosine 3',5' Monophosphate by Hydroalcoholic C. Koch Extract in Human Breast Cancer Cell Lines MCF-7 and MDA-Mb-468.

Breast Cancer (Auckl) 2017 23;11:1178223417690178. Epub 2017 Feb 23.

Department of Biology, Faculty of Science, University of Sistan and Baluchestan, Zahedan, Iran.

This study aimed to investigate the effect of hydroalcoholic C. Koch extract (HAWE) on phosphodiesterase 5 (PDE5) gene expression and cyclic guanosine 3',5' monophosphate (cGMP) signaling in the MCF-7 and MDA-Mb-468 cell lines. The effective dose (ED50) of HAWE was examined in both cell lines using a 3-(4,5-dimethylhiazol-2-yl)-2,5-diphenyltetrazolium bromide viability test, and the type of cell death was detected by flow cytometry. Read More

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February 2017

Anti-proliferative and apoptosis inducing potential of hydroalcoholic Achillea wilhelmsii C. Koch extract on human breast adenocarcinoma cell lines MCF-7 and MDA-Mb-468.

Pak J Pharm Sci 2016 Nov;29(6 Suppl):2397-2403

Department of Clinical Biochemistry, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.

Achillea wilhelmsii C. Koch contains a variety of components such as flavonoid. The previous studies showed that flavonoid has anti-cancer properties. Read More

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November 2016

Antibacterial activities of essential oils from Iranian medicinal plants on extended-spectrum β-lactamase-producing Escherichia coli.

Cell Mol Biol (Noisy-le-grand) 2016 Sep 19;62(9):75-82. Epub 2016 Sep 19.

Zabol University of Medical Sciences Zabol Iran

The extended-spectrum beta-lactamase (ESBL) -producing Escherichia coli strains can lead to various infections particularly urinary tract infections. The main objective of this investigation was to evaluate the antibacterial activities of essential oils (EOs) from different Iranian medicinal plants against TEM gene positive ESBL-producing E. coli strains isolated from urine samples of patients with urinary tract infections. Read More

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September 2016

The Chemical Composition of Achillea wilhelmsii C. Koch and Its Desirable Effects on Hyperglycemia, Inflammatory Mediators and Hypercholesterolemia as Risk Factors for Cardiometabolic Disease.

Molecules 2016 Mar 25;21(4):404. Epub 2016 Mar 25.

Department of Natural Drugs, Faculty of Pharmacy, University of Veterinary and Pharmaceutical Sciences, Palackého tř. 1, Brno 61242, Czech Republic.

This study was done to identify the content compounds of Achillea wilhelmsii (A. wilhelmsii) and to evaluate its hypoglycemic and anti-hypercholesterolemic activity and effect on inflammatory mediators. The extracts and fractions of A. Read More

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A comparative study of antimony accumulation in plants growing in two mining areas in Iran, Moghanlo, and Patyar.

Environ Sci Pollut Res Int 2015 Nov 17;22(21):16542-53. Epub 2015 Jun 17.

Department of Genetics, Faculty of Earth and Life Sciences, Vrije Universiteit, De Boelelaan 1085, 1081 HV, Amsterdam, The Netherlands.

Antimony occurs locally at high concentrations in some mineralized soils. Very little is known about behavior of antimony in plants. In this study, we analyzed the soil and vegetation of two mining areas in Iran, Patyar, and Moghanlo. Read More

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November 2015

Chemical composition, antioxidant activity and in vitro antibacterial activity of Achillea wilhelmsii C. Koch essential oil on methicillin-susceptible and methicillin-resistant Staphylococcus aureus spp.

3 Biotech 2015 Feb 5;5(1):39-44. Epub 2014 Feb 5.

, P.O. Box 7, Miki Cho Post Office, 3011-2, Ikenobe, Kagawa-Ken, 761-0799, Japan.

The present study investigated the chemical composition of the essential oil (EO) from aerial parts (flowering stage) of Achillea wilhelmsii C. Koch by GC-MS. In addition, the antioxidant activity of the EO as well as its antimicrobial activity against methicillin-susceptible and methicillin-resistant Staphylococcus aureus (MRSA) strains was tested. Read More

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February 2015

Potential preventive role of Iranian Achillea wilhelmsii C. Koch essential oils in acetaminophen-induced hepatotoxicity.

Bot Stud 2014 Dec 24;55(1):37. Epub 2014 Mar 24.

Department of Biochemistry, Faculty of Sciences, Payame-e-Noor University, Tehran, Iran.

Background: The essential oil of Achillea wilhelmsii C. Koch (100 & 200 mg/kg b.w, i. Read More

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December 2014

Protective effects of Iranian Achillea wilhelmsii essential oil on acetaminophen-induced oxidative stress in rat liver.

Pharm Biol 2015 Feb 22;53(2):220-7. Epub 2014 Sep 22.

Faculty of Medicine, Qom Branch, Islamic Azad University , Qom , Iran .

Context: Achillea wilhelmsii C. Koch (Asteraceae) is widely used in Iranian traditional medicine.

Objective: This in vivo study evaluates the hepatoprotective role of Iranian A. Read More

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February 2015

Chemical composition and biological activities of Iranian Achillea wilhelmsii L. essential oil: a high effectiveness against Candida spp. and Escherichia strains.

Nat Prod Res 2015 Feb 11;29(3):286-8. Epub 2014 Sep 11.

a Department of Horticultural Science , Faculty of Agricultural Science and Natural Resources, Science and Research Branch, Islamic Azad University , Tehran , Iran.

In the case of Achillea wilhelmsii, 30 compounds were identified representing 94.48% of the total oil with a yield of 0.82% w/w. Read More

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February 2015

The role for nitric oxide on the effects of hydroalcoholic extract of Achillea wilhelmsii on seizure.

Avicenna J Phytomed 2014 Jul;4(4):251-9

Department of Biochemistry, School of Medicine, Mashhad University of Medical Sciences, I. R. Iran.

Unlabelled: Objective : Nitric oxide (NO) plays an important role both as a consequence and as a cause of epileptic seizures. Regarding the central nervous system depressant effects of Achillea wilhelmsii (A. wilhelmsii), as well the effects of the plant on NO, this study was aimed to elucidate the possible role for nitric oxide on the effects of hydroalcoholic extract of A. Read More

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Antioxidant effect of Achillea wilhelmsii extract on pentylenetetrazole (seizure model)-induced oxidative brain damage in Wistar rats.

Indian J Physiol Pharmacol 2013 Oct-Dec;57(4):418-24

An important role for oxidative stress both as a consequence and as a cause of epileptic seizures has been suggested. Since Achillea wilhelmsii (A. wilhelmsii) has been considered to have the antioxidant effects as well as central nervous system depressant properties, the anti-seizure effects of the plant extract in addition to its effects on brain tissues oxidative damage were investigated in pentylenetetrazole (PTZ)-induced seizures model. Read More

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Mechanism of vasorelaxation induced by Achillea wilhelmsii in rat isolated thoracic aorta.

Adv Biomed Res 2014 14;3:91. Epub 2014 Mar 14.

Department of Physiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Background: Achillea wilhelmsii (A. wilhelmsii) is used in Iraninan folk medicine for the treatment of hypertension; also, in previous reports, the hypotensive and antihypertensive effects of this plant have been indicated. The aim of the present study is to investigate the vasorelaxant effect of the hydroalcholic extract of A. Read More

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Acute toxicity and antispasmodic activities of Achillea wilhelmsii C. Koch.

Pak J Pharm Sci 2014 Mar;27(2):309-15

Department of Pharmacy, Abasyn University, Peshawar, KP, Pakistan.

Since Achillea wilhelmsii is used as antispasmodic in traditional medicine, we conducted our current work to investigate its rationale on scientific grounds. Acute toxicity studies of crude methanol extract of Achillea wilhelmsii (Aw. CMeOH) is also performed. Read More

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Possible Mechanism(s) of the Relaxant Effects of Achillea wilhelmsii on Guinea-Pig Tracheal Chains.

Iran J Pharm Res 2013 ;12(2):381-7

Applied Physiology Research Center and Dept. of Physiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Achillea wilhelmsii have been used in folk remedies. The relaxant effects of the extract of A. wilhelmsii on tracheal chains of guinea pigs were examined. Read More

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November 2013

Chemical composition and anxiolytic evaluation of Achillea Wilhelmsii C. Koch essential oil in rat.

Res Pharm Sci 2013 Oct;8(4):269-75

Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, I.R. Iran.

Herbal based remedies are used worldwide to treat psychiatric disorders. The aim of this study was to analyse the essential oil composition of Achillea Wilhemsii C. Koch (Asteraceae) and to evaluate its anxiolytic effects in the elevated plus maze (EPM) model of anxiety in rat. Read More

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October 2013

First Report of Orobanche purpurea on Achillea wilhelmsii in Iran.

Plant Dis 2013 May;97(5):694

Department of Agronomy and Plant Breeding, University of Zanjan, Iran.

Achillea wilhelmsii C. Koch (Asteraceae) is a wild herb widely disturbed in Iran and known locally as yarrow. This plant is an important medicinal plant and it has been used for its analgesic, antiphlogistic, antispasmodic, and antibacterial effects in Iranian folk medicine. Read More

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