Biosystems 2021 Jun 17;204:104408. Epub 2021 Mar 17.
Department of Biochemistry and Molecular Biology, Universitat de València, C. Dr. Moliner 50, 46100, Burjassot, Spain; Institute for Integrative Systems Biology (I(2)SysBio), Universitat de València-CSIC, C. José Beltrán 2, 46980, Paterna, Spain. Electronic address:
The publication in the late 1960s of Lynn Margulis endosymbiotic proposal is a scientific milestone that brought to the fore of evolutionary discussions the issue of the origin of nucleated cells. Although it is true that the times were ripe, the timely publication of Lynn Margulis' original paper was the product of an intellectually bold 29-years old scientist, who based on the critical analysis of the available scientific information produced an all-encompassing, sophisticated narrative scheme on the origin of eukaryotic cells as a result of the evolution of prokaryotic consortia and, in bold intellectual stroke, put it all in the context of planetary evolution. A critical historical reassessment of her original proposal demonstrates that her hypothesis was not a simple archival outline of past schemes, but a renewed historical narrative of prokaryotic evolution and the role of endosymbiosis in the origin of eukaryotes. Read More